Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 5 January 2001:
Vol. 291. no. 5501, pp. 118 - 120
DOI: 10.1126/science.291.5501.118
Prev | Table of Contents | Next

Reports

Broad-Spectrum Mildew Resistance in Arabidopsis thaliana Mediated by RPW8

Shunyuan Xiao, Simon Ellwood, Ozer Calis, Elaine Patrick, Tianxian Li, Mark Coleman, John G. Turner*

Plant disease resistance (R) genes control the recognition of specific pathogens and activate subsequent defense responses. We show that the Arabidopsis thaliana locus RESISTANCE TO POWDERY MILDEW8 (RPW8) contains two naturally polymorphic, dominant R genes, RPW8.1 and RPW8.2, which individually control resistance to a broad range of powdery mildew pathogens. Although the predicted RPW8.1 and RPW8.2 proteins are different from the previously characterized R proteins, they induce localized, salicylic acid-dependent defenses similar to those induced by R genes that control specific resistance. Apparently, broad-spectrum resistance mediated by RPW8 uses the same mechanisms as specific resistance.

School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK.
*   To whom correspondence should be addressed. E-mail: j.g.turner{at}uea.ac.uk

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Specific Targeting of the Arabidopsis Resistance Protein RPW8.2 to the Interfacial Membrane Encasing the Fungal Haustorium Renders Broad-Spectrum Resistance to Powdery Mildew.
W. Wang, Y. Wen, R. Berkey, and S. Xiao (2009)
PLANT CELL 21, 2898-2913
   Abstract »    Full Text »    PDF »
Temporal Global Expression Data Reveal Known and Novel Salicylate-Impacted Processes and Regulators Mediating Powdery Mildew Growth and Reproduction on Arabidopsis.
D. Chandran, Y. C. Tai, G. Hather, J. Dewdney, C. Denoux, D. G. Burgess, F. M. Ausubel, T. P. Speed, and M. C. Wildermuth (2009)
Plant Physiology 149, 1435-1451
   Abstract »    Full Text »    PDF »
An Inositolphosphorylceramide Synthase Is Involved in Regulation of Plant Programmed Cell Death Associated with Defense in Arabidopsis.
W. Wang, X. Yang, S. Tangchaiburana, R. Ndeh, J. E. Markham, Y. Tsegaye, T. M. Dunn, G.-L. Wang, M. Bellizzi, J. F. Parsons, et al. (2008)
PLANT CELL 20, 3163-3179
   Abstract »    Full Text »    PDF »
The Coiled-Coil and Nucleotide Binding Domains of the Potato Rx Disease Resistance Protein Function in Pathogen Recognition and Signaling.
G. J. Rairdan, S. M. Collier, M. A. Sacco, T. T. Baldwin, T. Boettrich, and P. Moffett (2008)
PLANT CELL 20, 739-751
   Abstract »    Full Text »    PDF »
Genome-Wide Expression Profiling Arabidopsis at the Stage of Golovinomyces cichoracearum Haustorium Formation.
G. Fabro, J. A. Di Rienzo, C. A. Voigt, T. Savchenko, K. Dehesh, S. Somerville, and M. E. Alvarez (2008)
Plant Physiology 146, 1421-1439
   Abstract »    Full Text »    PDF »
Identification and Characterization of Nucleotide-Binding Site-Leucine-Rich Repeat Genes in the Model Plant Medicago truncatula.
C. Ameline-Torregrosa, B.-B. Wang, M. S. O'Bleness, S. Deshpande, H. Zhu, B. Roe, N. D. Young, and S. B. Cannon (2008)
Plant Physiology 146, 5-21
   Abstract »    Full Text »    PDF »
Intraspecific Genetic Variations, Fitness Cost and Benefit of RPW8, A Disease Resistance Locus in Arabidopsis thaliana.
U. Orgil, H. Araki, S. Tangchaiburana, R. Berkey, and S. Xiao (2007)
Genetics 176, 2317-2333
   Abstract »    Full Text »    PDF »
Within-Species Flagellin Polymorphism in Xanthomonas campestris pv campestris and Its Impact on Elicitation of Arabidopsis FLAGELLIN SENSING2-Dependent Defenses.
W. Sun, F. M. Dunning, C. Pfund, R. Weingarten, and A. F. Bent (2006)
PLANT CELL 18, 764-779
   Abstract »    Full Text »    PDF »
The Broad-Spectrum Blast Resistance Gene Pi9 Encodes a Nucleotide-Binding Site-Leucine-Rich Repeat Protein and Is a Member of a Multigene Family in Rice.
S. Qu, G. Liu, B. Zhou, M. Bellizzi, L. Zeng, L. Dai, B. Han, and G.-L. Wang (2006)
Genetics 172, 1901-1914
   Abstract »    Full Text »    PDF »
RESISTANCE TO FUSARIUM OXYSPORUM 1, a Dominant Arabidopsis Disease-Resistance Gene, Is Not Race Specific.
A. C. Diener and F. M. Ausubel (2005)
Genetics 171, 305-321
   Abstract »    Full Text »    PDF »
Interaction-Dependent Gene Expression in Mla-Specified Response to Barley Powdery Mildew.
R. A. Caldo, D. Nettleton, and R. P. Wise (2004)
PLANT CELL 16, 2514-2528
   Abstract »    Full Text »    PDF »
Origin and Maintenance of a Broad-Spectrum Disease Resistance Locus in Arabidopsis.
S. Xiao, B. Emerson, K. Ratanasut, E. Patrick, C. O'Neill, I. Bancroft, and J. G. Turner (2004)
Mol. Biol. Evol. 21, 1661-1672
   Abstract »    Full Text »    PDF »
Gene RB cloned from Solanum bulbocastanum confers broad spectrum resistance to potato late blight.
J. Song, J. M. Bradeen, S. K. Naess, J. A. Raasch, S. M. Wielgus, G. T. Haberlach, J. Liu, H. Kuang, S. Austin-Phillips, C. R. Buell, et al. (2003)
PNAS 100, 9128-9133
   Abstract »    Full Text »    PDF »
Genome-Wide Analysis of NBS-LRR-Encoding Genes in Arabidopsis.
B. C. Meyers, A. Kozik, A. Griego, H. Kuang, and R. W. Michelmore (2003)
PLANT CELL 15, 809-834
   Abstract »    Full Text »    PDF »
Enhanced Transcription of the Arabidopsis Disease Resistance Genes RPW8.1 and RPW8.2 via a Salicylic Acid-Dependent Amplification Circuit Is Required for Hypersensitive Cell Death.
S. Xiao, S. Brown, E. Patrick, C. Brearley, and J. G. Turner (2003)
PLANT CELL 15, 33-45
   Abstract »    Full Text »    PDF »
Organization, Expression and Evolution of a Disease Resistance Gene Cluster in Soybean.
M. A. Graham, L. F. Marek, and R. C. Shoemaker (2002)
Genetics 162, 1961-1977
   Abstract »    Full Text »    PDF »
Plant Disease Susceptibility Genes?.
N. A. Eckardt (2002)
PLANT CELL 14, 1983-1986
   Full Text »    PDF »
Ubiquitin ligase-associated protein SGT1 is required for host and nonhost disease resistance in plants.
J. R. Peart, R. Lu, A. Sadanandom, I. Malcuit, P. Moffett, D. C. Brice, L. Schauser, D. A. W. Jaggard, S. Xiao, M. J. Coleman, et al. (2002)
PNAS 99, 10865-10869
   Abstract »    Full Text »    PDF »
Biochemical Characterization of the Kinase Domain of the Rice Disease Resistance Receptor-like Kinase XA21.
G.-Z. Liu, L.-Y. Pi, J. C. Walker, P. C. Ronald, and W.-Y. Song (2002)
J. Biol. Chem. 277, 20264-20269
   Abstract »    Full Text »    PDF »
Arabidopsis SGT1b Is Required for Defense Signaling Conferred by Several Downy Mildew Resistance Genes.
M. Tor, P. Gordon, A. Cuzick, T. Eulgem, E. Sinapidou, F. Mert-Turk, C. Can, J. L. Dangl, and E. B. Holub (2002)
PLANT CELL 14, 993-1003
   Abstract »    Full Text »    PDF »
Epigenetic variation in Arabidopsis disease resistance.
T. L. Stokes, B. N. Kunkel, and E. J. Richards (2002)
Genes & Dev. 16, 171-182
   Abstract »    Full Text »    PDF »
Sentinels of Disease. Plant Resistance Genes.
R. Fluhr (2001)
Plant Physiology 127, 1367-1374
   Full Text »    PDF »
Quantitative Trait Loci Analysis of Powdery Mildew Disease Resistance in the Arabidopsis thaliana Accession Kashmir-1.
I. W. Wilson, C. L. Schiff, D. E. Hughes, and S. C. Somerville (2001)
Genetics 158, 1301-1309
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)