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Science 8 December 2000:
Vol. 290. no. 5498, pp. 1881 - 1883
DOI: 10.1126/science.290.5498.1881

News Focus

INFECTIOUS DISEASES:
Has Leishmaniasis Become Endemic in the U.S.?

Martin Enserink

Believed to be all but absent from United States, the Leishmania parasite has infected more than 1000 hunting dogs in 21 U.S. states and the Canadian province of Ontario. Nobody is claiming that the disease is about to run riot among the U.S. population. But the widespread outbreak in dogs has experts wondering whether visceral leishmaniasis--which sickens over half a million people yearly in South America, Africa, the Mediterranean, and India--has become an endemic disease in North America.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Incidence and Time Course of Leishmania infantum Infections Examined by Parasitological, Serologic, and Nested-PCR Techniques in a Cohort of Naive Dogs Exposed to Three Consecutive Transmission Seasons.
G. Oliva, A. Scalone, V. Foglia Manzillo, M. Gramiccia, A. Pagano, T. Di Muccio, and L. Gradoni (2006)
J. Clin. Microbiol. 44, 1318-1322
   Abstract »    Full Text »    PDF »
Evaluation of Enzyme-Linked Immunosorbent Assays, an Immunofluorescent-Antibody Test, and Two Rapid Tests (Immunochromatographic-Dipstick and Gel Tests) for Serological Diagnosis of Symptomatic and Asymptomatic Leishmania Infections in Dogs.
M. Mettler, F. Grimm, G. Capelli, H. Camp, and P. Deplazes (2005)
J. Clin. Microbiol. 43, 5515-5519
   Abstract »    Full Text »    PDF »
Polymorphism of Slc11a1 (Nramp1) Gene and Canine Leishmaniasis in a Case-Control Study.
E. Sanchez-Robert, L. Altet, A. Sanchez, and O. Francino (2005)
J. Hered. 96, 755-758
   Abstract »    Full Text »    PDF »
Development of a Dipstick Assay for Detection of Leishmania-Specific Canine Antibodies.
H. D. F. H. Schallig, L. Cardoso, M. Hommers, N. Kroon, G. Belling, M. Rodrigues, S. J. Semiao-Santos, and H. Vetter (2004)
J. Clin. Microbiol. 42, 193-197
   Abstract »    Full Text »    PDF »
Role of ABC transporters in secretion of cholesterol from liver into bile.
D. M. Small (2003)
PNAS 100, 4-6
   Full Text »    PDF »



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