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Science 28 July 2000:
Vol. 289. no. 5479, pp. 563 - 564
DOI: 10.1126/science.289.5479.563
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Perspectives

BIOCHEMISTRY:
All in the Ubiquitin Family

Mark Hochstrasser

The job of a protein can be altered by addition of molecules such as ubiquitin or the related ubiquitin-like modifiers, which bring about changes in the protein's localization, conformation, or its interactions with other proteins. In a comprehensive Perspective, Hochstrasser brings us up to date with the many new members of the ubiquitin modifier family and their multitudinous and diverse protein targets.

The author is at Yale University, Department of Molecular Biophysics and Biochemistry, 266 Whitney Avenue, New Haven, CT 06520, USA. E-mail: mark.hochstrasser{at}yale.edu

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