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It has been assumed that the new members of the p53 protein family, p63 and p73, would have the same job as p53, namely, forcing cells to die if they or their DNA is damaged. Now, as Morrison and Kinoshita explain in their Perspective, one particular form of p73 has been found to be a survival factor rather than a death factor for sympathetic neurons during development (Pozniak et al.).
The authors are in the Department of Neurological Surgery, University of Washington School of Medicine, Box 356470, Seattle, WA 98195-6470, USA. E-mail: yael{at}u.washington.edu
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In Science Magazine
PERSPECTIVES
Neil A. R. Gow, Alistair J. P. Brown, and Frank C. Odds (14 July 2000) Science289 (5477), 256.
[DOI: 10.1126/science.289.5477.256] |Summary »|Full Text »
REPORTS
Christine D. Pozniak, Stevo Radinovic, Annie Yang, Frank McKeon, David R. Kaplan, and Freda D. Miller (14 July 2000) Science289 (5477), 304.
[DOI: 10.1126/science.289.5477.304] |Abstract »|Full Text »|PDF »
REPORTS
Christina M. Hull, Ryan M. Raisner, and Alexander D. Johnson (14 July 2000) Science289 (5477), 307.
[DOI: 10.1126/science.289.5477.307] |Abstract »|Full Text »|PDF »
REPORTS
B. B. Magee and P. T. Magee (14 July 2000) Science289 (5477), 310.
[DOI: 10.1126/science.289.5477.310] |Abstract »|Full Text »|PDF »
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