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Science 24 March 2000:
Vol. 287. no. 5461, pp. 2218 - 2220
DOI: 10.1126/science.287.5461.2218
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The Drosophila Genome Sequence: Implications for Biology and Medicine

Thomas B. Kornberg, 1 and Mark A. Krasnow 2

The 120-megabase euchromatic portion of the Drosophila melanogaster genome has been sequenced. Because the genome is compact and many genetic tools are available, and because fly cell biology and development have much in common with mammals, this sequence may be the Rosetta stone for deciphering the human genome.

1 Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA 94143, USA.
2 Howard Hughes Medical Institute and Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA.

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