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Science 24 March 2000:
Vol. 287. no. 5461, p. 2183
DOI: 10.1126/science.287.5461.2183

News

Are Sequencers Ready to 'Annotate' the Human Genome?

Elizabeth Pennisi

To be useful, a genome must be annotated--that is, documented to provide at a minimum the putative start, stop, and structure of each gene. The genomics community is now scrambling to figure out the best way to annotate the human genome, the rough draft of which is due out this spring. The challenge will be even more daunting than the one faced by fruit fly biologists in analyzing the Drosophila genome (see main text).

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
PeerGAD: a peer-review-based and community-centric web application for viewing and annotating prokaryotic genome sequences.
M. D. D'Ascenzo, A. Collmer, and G. B. Martin (2004)
Nucleic Acids Res. 32, 3124-3135
   Abstract »    Full Text »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)