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Science 7 January 2000:
Vol. 287. no. 5450, pp. 52 - 53
DOI: 10.1126/science.287.5450.52
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Perspectives

BIOCHEMISTRY:
Reading the Worm Genome

Stuart K. Kim

The genome sequencing of complex organisms has reaped a wealth of information about genes. The next step is to find out what the proteins encoded by these genes do and how they interact with each other. In a Perspective, Stuart Kim, discusses the application of yeast two-hybrid technology to working out the complex interactions between the many proteins of the worm C. elegans (Walhout et al.). This new work is a first step in the creation of a global protein interaction map for the nematode.

The author is in the Department of Developmental Biology and Genetics, Stanford University Medical Center, 279 Campus Drive, Stanford, CA 94305-5329, USA. E-mail: kim{at}cmgm.stanford.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Milestone or Genomania? The Relevance of the Human Genome Project to Biological Aging and the Age-Related Diseases.
H. T. Blumenthal (2001)
J. Gerontol. A Biol. Sci. Med. Sci. 56, M529-537
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Science. ISSN 0036-8075 (print), 1095-9203 (online)