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Science 9 July 1999:
Vol. 285. no. 5425, pp. 175 - 177
DOI: 10.1126/science.285.5425.175
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News of the Week

NEUROBIOLOGY:
An Immunization Against Alzheimer's?

Marcia Barinaga

New findings raise the startling possibility of someday immunizing people to prevent or even reverse the mental devastation of Alzheimer's disease. A team reports this week in Nature that, in mice genetically engineered to develop an Alzheimer's-like condition, immunization with b-amyloid (Ab), the protein fragment that forms the plaques in the brain that are the hallmark of the disease, reversed or prevented plaque formation and neural damage. One big question mark, however, is that even if immunization prevented plaque formation in humans, no one is certain yet that plaque actually causes Alzheimer's symptoms.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Vaccine Protects Mice from Alzheimer-Like Disease.
(1999)
Journal Watch Neurology 1999, 15
   Full Text »
Vaccine Protects Mice from Alzheimer-Like Disease.
(1999)
Journal Watch (General) 1999, 3
   Full Text »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)