Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 26 March 1999:
Vol. 283. no. 5410, pp. 2027 - 2028
DOI: 10.1126/science.283.5410.2027
Prev | Table of Contents | Next

Perspectives

GENOMICS:
Mix and Match in the Tree of Life

James A. Lake, Ravi Jain, Maria C. Rivera

Genes for ribosomal RNA have been used to decipher the evolutionary relationship between eukaryotes and prokaryotes. However, as Lake and colleagues point out in their Perspective, the availability of complete genome sequences for many bacteria (prokaryotes) and for the yeast (a eukaryote) has called into question long-held views about the evolutionary tree of life. The Perspective discusses the emerging notion of chimerism in prokaryotic and eukaryotic genomes, which arises through transfer of groups of functionally similar genes between organisms.

The authors are in the Molecular Biology Institute and MCD Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA. E-mail: lake{at}mbi.ucla.edu

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Inferring Phylogenetic Networks by the Maximum Parsimony Criterion: A Case Study.
G. Jin, L. Nakhleh, S. Snir, and T. Tuller (2007)
Mol. Biol. Evol. 24, 324-337
   Abstract »    Full Text »    PDF »
Computing prokaryotic gene ubiquity: Rescuing the core from extinction.
R. L. Charlebois and W. F. Doolittle (2004)
Genome Res. 14, 2469-2477
   Abstract »    Full Text »    PDF »
Should names reflect the evolution of bacterial species?.
F. Dellaglio, G. E. Felis, and J.-E. Germond (2004)
Int J Syst Evol Microbiol 54, 279-281
   Abstract »    Full Text »    PDF »
GAPDH Gene Diversity in Spirochetes: A Paradigm for Genetic Promiscuity.
R. M. Figge and R. Cerff (2001)
Mol. Biol. Evol. 18, 2240-2249
   Abstract »    Full Text »    PDF »
Evolution of Cell Recognition by Viruses.
E. Baranowski, C. M. Ruiz-Jarabo, and E. Domingo (2001)
Science 292, 1102-1105
   Abstract »    Full Text »
A Hypothesis for DNA Viruses as the Origin of Eukaryotic Replication Proteins.
L. P. Villarreal and V. R. DeFilippis (2000)
J. Virol. 74, 7079-7084
   Abstract »    Full Text »
Whole-genome Trees Based on the Occurrence of Folds and Orthologs: Implications for Comparing Genomes on Different Levels.
J. Lin and M. Gerstein (2000)
Genome Res. 10, 808-818
   Abstract »    Full Text »
Cloning, Expression, and Substrate Specificity of a Fungal Chymotrypsin. EVIDENCE FOR LATERAL GENE TRANSFER FROM AN ACTINOMYCETE BACTERIUM.
S. E. Screen and R. J. St. Leger (2000)
J. Biol. Chem. 275, 6689-6694
   Abstract »    Full Text »    PDF »
Similarities between the DNA replication initiators of Gram-negative bacteria plasmids (RepA) and eukaryotes (Orc4p)/archaea (Cdc6p).
R. Giraldo and R. Diaz-Orejas (2001)
PNAS 98, 4938-4943
   Abstract »    Full Text »    PDF »
Horizontal transfer of oncogenes by uptake of apoptotic bodies.
A. Bergsmedh, A. Szeles, M. Henriksson, A. Bratt, M. J. Folkman, A.-L. Spetz, and L. Holmgren (2001)
PNAS 98, 6407-6411
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)