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Science 11 December 1998:
Vol. 282. no. 5396, pp. 2003 - 2004
DOI: 10.1126/science.282.5396.2003
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Perspectives

MOLECULAR BIOLOGY:
Nuclear Functions Charge Ahead

Anita K. Hopper

A new study in this issue of Science on nuclei of the frog Xenopus (Lund and Dahlberg) shows that, after being transcribed from DNA, transfer RNA molecules must be attached to their amino acid before being exported from the nucleus. This departure from the standard dogma is discussed by Hopper in her Perspective, as is the applicability of this system to other RNAs and other species.

The author is in the Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. E-mail: ahopper{at}psu.edu

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