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Science 4 December 1998:
Vol. 282. no. 5395, pp. 1844 - 1845
DOI: 10.1126/science.282.5395.1844
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Perspectives

AMERSHAM PHARMACIA BIOTECH & SCIENCE PRIZE:
The Rotary Enzyme of the Cell: The Rotation of F1-ATPase

Hiroyuki Noji

The winner of this year's Amersham Pharmacia Biotech & Science Prize is Hiroyuki Noji, from Japan. In his winning essay , Noji describes his thesis experiments in which he visualized the rotation of the gamma subunit of F1-ATPase by attaching long actin molecules. This result proved that the gamma subunit does indeed rotate within the bearing-like structure created by the alpha and beta subunits. F1-ATPase is a true molecular motor, converting chemical to mechanical energy on a very small scale.

The author is with the "Genetic Programming" Team 13, Teikyo University Biotechnology Research Center 3F, Nogawa, Kawasaki, Japan. E-mail: noji{at}phys.keio.ac.jp

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Oxidative Phosphorylation at the fin de siècle.
M. Saraste (1999)
Science 283, 1488-1493
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