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Science 27 November 1998:
Vol. 282. no. 5394, p. 1609
DOI: 10.1126/science.282.5394.1609i
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Progression through the cell cycle is governed in part by the anaphase promoting complex, which causes the controlled degradation of kinases and phosphatases that are involved in orchestrating DNA replication and cell division. Zachariae et al. (p. 1721) describe a protein, Hct1, that controls the activity of the anaphase promoting complex and restricts its activity to the correct phase of the cell cycle.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)