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Science 31 July 1998:
Vol. 281. no. 5377, pp. 658 - 659
DOI: 10.1126/science.281.5377.658
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Perspectives

PROTEIN SYNTHESIS:
All You Need Is RNA

Paul Schimmel and Rebecca Alexander

What does it take to string amino acids together to form a protein? This essential process of life, synthesis of peptide bonds, can be accomplished by naked RNA molecules, as Schimmel and Alexander explain in their Perspective. This notion, bolstered by the results of Nitta et al. in this week's issue, paints a picture of how the first proteins may have been synthesized in an ancient world where RNA molecules were the precursors of life.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A Mutation in GRS1, a Glycyl-tRNA Synthetase, Affects 3'-End Formation in Saccharomyces cerevisiae.
C. Magrath and L. E. Hyman (1999)
Genetics 152, 129-141
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