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Science 29 May 1998:
Vol. 280. no. 5368, p. 1403
DOI: 10.1126/science.280.5368.1403

Research Commentaries

HUMAN GENETICS:
Update: More Deafness Genes

Karen P. Steel and Steve D. M. Brown

Hereditary deafness can be the result of defects in any one of a large number of genes. Two more of these have now been identified, in Nature Genetics and in this issue of Science (see Probst et al. and Wang et al.), as coding for a protein called a-tectorin and an unconventional myosin. In their commentary, Steel and Brown explain how the identification of these and other genes underlying deafness allows a proposal to be put forward for their role in hearing.


K. P. Steel is at the Medical Research Council (MRC), Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK. E-mail: karen{at}ihr.mrc.ac.uk. S. D. M. Brown is in the MRC Mammalian Genetics Unit, Harwell, Oxon OX11 0RD, UK.

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