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Science 8 May 1998:
Vol. 280. no. 5365, pp. 852 - 853
DOI: 10.1126/science.280.5365.852
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Research Commentaries

Also see the archival list of Science's Compass: Research commentaries

BIOCHEMISTRY:
Enhanced: The Era of Pathway Quantification

Daniel E. Koshland Jr.

Biochemistry is in its third era, the Era of Quantification. So argues Koshland in his commentary, in which he describes this era as one in which the rates of production and degradation of substrates and products of biochemical pathways are quantified. In an example of this sort of analysis by Ferrel and Machleder in this issue, cell cycle regulation by the MAP kinase cascade is analyzed.

The author is in the Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. E-mail: dek{at}uclink4.berkeley.edu

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