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Science 27 June 1997:
Vol. 276. no. 5321, pp. 2054 - 2057
DOI: 10.1126/science.276.5321.2054
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Reports

Receptor-Mediated Activation of a MAP Kinase in Pathogen Defense of Plants

Wilco Ligterink, Thomas Kroj, Uta zur Nieden, Heribert Hirt, * Dierk Scheel

Parsley cells recognize the fungal plant pathogen Phytophthora sojae through a plasma membrane receptor. A pathogen-derived oligopeptide elicitor binds to this receptor and thereby stimulates a multicomponent defense response through sequential activation of ion channels and an oxidative burst. An elicitor-responsive mitogen-activated protein (MAP) kinase was identified that acts downstream of the ion channels but independently or upstream of the oxidative burst. Upon receptor-mediated activation, the MAP kinase is translocated to the nucleus where it might interact with transcription factors that induce expression of defense genes.

W. Ligterink and H. Hirt, Institute of Microbiology and Genetics, Vienna Biocenter, Dr.-Bohr-Gasse 9, A-1030 Vienna, Austria.
T. Kroj, U. zur Nieden, D. Scheel, Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle/Saale, Germany.
*   To whom correspondence should be addressed. E-mail: hehi{at}gem.univie.ac.at

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