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Science 6 June 1997:
Vol. 276. no. 5318, pp. 1551 - 1555
DOI: 10.1126/science.276.5318.1551
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Reports

Orientation Selectivity in Pinwheel Centers in Cat Striate Cortex

Pedro E. Maldonado, *dagger Imke Gödecke, * Charles M. Gray, Tobias Bonhoeffer

In primary visual cortex of higher mammals neurons are grouped according to their orientation preference, forming "pinwheels" around "orientation centers." Although the general structure of orientation maps is largely resolved, the microscopic arrangement of neuronal response properties in the orientation centers has remained elusive. The tetrode technique, enabling multiple single-unit recordings, in combination with intrinsic signal imaging was used to reveal the fine-grain structure of orientation maps in these locations. The results show that orientation centers represent locations where orientation columns converge containing normal, sharply tuned neurons of different orientation preference lying in close proximity.

P. E. Maldonado, Max-Planck-Institute for Psychiatry, Am Klopferspitz 18A, 82152 München-Martinsried, Germany, and The Center for Neuroscience, University of California, Davis, CA 95616, USA.
I. Gödecke and T. Bonhoeffer, Max-Planck-Institute for Psychiatry, Am Klopferspitz 18A, 82152 München-Martinsried, Germany.
C. M. Gray, The Center for Neuroscience and the Section of Neurobiology, Physiology and Behavior, University of California, Davis, CA 95616, USA.
*   These authors contributed equally to the work.

dagger    To whom correspondence should be addressed at The Center for Neuroscience, University of California, Davis, CA 95616, USA. E-mail: pedro{at}chaos.ucdavis.edu

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