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Science 30 May 1997:
Vol. 276. no. 5317, p. 1309
DOI: 10.1126/science.276.5317.1309n

This Week in Science

Understanding the mechanism of transport of viral RNA from the nucleus to the cytoplasm of the infected cell is important in studying the replication cycle of the virus and in shedding light on normal cellular processes. Tang et al. found that the constitutive transport element (CTE) of simian retrovirus interacted with a cellular protein, helicase A. Both proteins then moved from the nucleus to the cytoplasm. The role of CTE in exporting RNA was shown to be associated with its ability to bind helicase A.





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