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Science 2 May 1997:
Vol. 276. no. 5313, pp. 707 - 712
DOI: 10.1126/science.276.5313.707
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Articles

Microbial Pathogenesis: Genomics and Beyond

Evelyn J. Strauss, * Stanley Falkow

The growing number of complete microbial genome sequences provides a powerful tool for studying the biology of microorganisms. In combination with assays for function, genomic-based approaches can facilitate efficient and directed research strategies to elucidate mechanisms of bacterial pathogenicity. As genomic information accrues, the challenge remains to construct a picture of the biology that accurately reflects how individual genes collaborate to create the complex world of microbial specialization.

The authors are in the Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305-5402, USA.
*   To whom correspondence should be addressed. E-mail: estrauss{at}cmgm.stanford.edu

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