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Science 14 June 1996:
Vol. 272. no. 5268, pp. 1665 - 1668
DOI: 10.1126/science.272.5268.1665
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Reports

Optical Imaging of Functional Organization in the Monkey Inferotemporal Cortex

Gang Wang, Keiji Tanaka, * Manabu Tanifuji

To investigate the functional organization of object recognition, the technique of optical imaging was applied to the primate inferotemporal cortex, which is thought to be essential for object recognition. The features critical for the activation of single cells were first determined in unit recordings with electrodes. In the subsequent optical imaging, presentation of the critical features activated patchy regions around 0.5 millimeters in diameter, covering the site of the electrode penetration at which the critical feature had been determined. Because signals in optical imaging reflect average neuronal activities in the regions, the result directly indicates the regional clustering of cells responding to similar features.

G. Wang, Laboratory for Neural Information Processing, Frontier Research Program, Institute of Physical and Chemical Research (RIKEN), and Department of Physiology II, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima-shi, Kagoshima, 890, Japan.
K. Tanaka, Laboratory for Neural Information Processing, Frontier Research Program, and Information Science Laboratory, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama, 351-01, Japan.
M. Tanifuji, Department of Information Science, Fukui University, and Precursory Research for Embryonic Science and Technology (PRESTO), Research Development Corporation of Japan, 3-9-1 Bunkyo, Fukui, 910, Japan.
* To whom correspondence should be addressed.


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