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Science 17 November 1995:
Vol. 270. no. 5239, p. 1159
DOI: 10.1126/science.270.5239.1159
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Perspectives

Louis H. Philipson

In an update of a previous Perspective [L. H. Philipson and D. F. Steiner, Science 268, 372 (1995)], Philipson discusses the molecular basis for Ksubscript ATP, a potassium current that mediates glucose regulation of insulin secretion. A prediction in the previous Perspective is borne out by a paper in this issue of Science (Inagaki et al., p. 1166), which reports the cloning of a new inward rectifier potassium channel and shows that Ksubscript ATP is formed when this channel combines with the sulfonylurea receptor.

The author is in the Department of Medicine and is on the Committee on Cell Physiology, University of Chicago, Chicago, IL 60637, USA. E-mail: l-philipson@uchicago.edu


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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