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Science 11 August 1995:
Vol. 269. no. 5225, pp. 843 - 846
DOI: 10.1126/science.7638602

Articles

Science, Vol 269, Issue 5225, 843-846
Copyright © 1995 by American Association for the Advancement of Science


articles

Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance

MR Grant, L Godiard, E Straube, T Ashfield, J Lewald, A Sattler, RW Innes, and JL Dangl

Max-Delbruck Laboratory, Koln, Germany.

Plants can recognize pathogens through the action of disease resistance (R) genes, which confer resistance to pathogens expressing unique corresponding avirulence (avr) genes. The molecular basis of this gene-for-gene specificity is unknown. The Arabidopsis thaliana RPM1 gene enables dual specificity to pathogens expressing either of two unrelated Pseudomonas syringae avr genes. Despite this function, RPM1 encodes a protein sharing molecular features with recently described single-specificity R genes. Surprisingly, RPM1 is lacking from naturally occurring, disease-susceptible Arabidopsis accessions.


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D. P. Matton, D. T. Luu, Q. Xike, G. Laublin, M. O'Brien, O. Maes, D. Morse, and M. Cappadocia (1999)
PLANT CELL 11, 2087-2098
   Abstract »    Full Text »
High gene density is conserved at syntenic loci of small and large grass genomes.
C. Feuillet and B. Keller (1999)
PNAS 96, 8265-8270
   Abstract »    Full Text »    PDF »
Molecular Characterization of the Maize Rp1-D Rust Resistance Haplotype and Its Mutants.
N. Collins, J. Drake, M. Ayliffe, Q. Sun, J. Ellis, S. Hulbert, and T. Pryor (1999)
PLANT CELL 11, 1365-1376
   Abstract »    Full Text »
The Rx Gene from Potato Controls Separate Virus Resistance and Cell Death Responses.
A. Bendahmane, K. Kanyuka, and D. C. Baulcombe (1999)
PLANT CELL 11, 781-792
   Abstract »    Full Text »
Isolation of Ethylene-Insensitive Soybean Mutants That Are Altered in Pathogen Susceptibility and Gene-for-Gene Disease Resistance.
T. Hoffman, J. S. Schmidt, X. Zheng, and A. F. Bent (1999)
Plant Physiology 119, 935-950
   Abstract »    Full Text »
Diversity and molecular evolution of the RPS2 resistance gene in Arabidopsis thaliana.
A. L. Caicedo, B. A. Schaal, and B. N. Kunkel (1999)
PNAS 96, 302-306
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Suppressors of the Arabidopsis lsd5 Cell Death Mutation Identify Genes Involved in Regulating Disease Resistance Responses.
J.-B. Morel and J. L. Dangl (1999)
Genetics 151, 305-319
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Independent deletions of a pathogen-resistance gene in Brassica and Arabidopsis.
M. R. Grant, J. M. McDowell, A. G. Sharpe, M. de Torres Zabala, D. J. Lydiate, and J. L. Dangl (1998)
PNAS 95, 15843-15848
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The Arabidopsis thaliana RPM1 disease resistance gene product is a peripheral plasma membrane protein that is degraded coincident with the hypersensitive response.
D. C. Boyes, J. Nam, and J. L. Dangl (1998)
PNAS 95, 15849-15854
   Abstract »    Full Text »    PDF »



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