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Science 11 August 1995: Vol. 269. no. 5225, pp. 843 - 846 DOI: 10.1126/science.7638602
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Articles
Science, Vol 269, Issue 5225, 843-846
Copyright © 1995 by American Association for the Advancement of Science
Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance
MR Grant,
L Godiard,
E Straube,
T Ashfield,
J Lewald,
A Sattler,
RW Innes,
and
JL Dangl
Max-Delbruck Laboratory, Koln, Germany.
Plants can recognize pathogens through the action of disease resistance (R) genes, which confer resistance to pathogens expressing unique corresponding avirulence (avr) genes. The molecular basis of this gene-for-gene specificity is unknown. The Arabidopsis thaliana RPM1 gene enables dual specificity to pathogens expressing either of two unrelated Pseudomonas syringae avr genes. Despite this function, RPM1 encodes a protein sharing molecular features with recently described single-specificity R genes. Surprisingly, RPM1 is lacking from naturally occurring, disease-susceptible Arabidopsis accessions.
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12, 2033-2046
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- Evidence for a Role of the N Terminus and Leucine-Rich Repeat Region of the Mi Gene Product in Regulation of Localized Cell Death.
- C.-F. Hwang, A. V. Bhakta, G. M. Truesdell, W. M. Pudlo, and V. M. Williamson (2000)
PLANT CELL
12, 1319-1330
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- Comparative Genetics of Nucleotide Binding Site-Leucine Rich Repeat Resistance Gene Homologues in the Genomes of Two Dicotyledons: Tomato and Arabidopsis.
- Q. Pan, Y.-S. Liu, O. Budai-Hadrian, M. Sela, L. Carmel-Goren, D. Zamir, and R. Fluhr (2000)
Genetics
155, 309-322
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- Members of the Arabidopsis HRT/RPP8 Family of Resistance Genes Confer Resistance to Both Viral and Oomycete Pathogens.
- M. B. Cooley, S. Pathirana, H.-J. Wu, P. Kachroo, and D. F. Klessig (2000)
PLANT CELL
12, 663-676
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- Reply: Establishing a Paradigm for the Generation of New S Alleles.
- D. P. Matton, D. T. Luu, D. Morse, and M. Cappadocia (2000)
PLANT CELL
12, 313-316
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- The Mla (Powdery Mildew) Resistance Cluster Is Associated With Three NBS-LRR Gene Families and Suppressed Recombination Within a 240-kb DNA Interval on Chromosome 5S (1HS) of Barley.
- F. Wei, K. Gobelman-Werner, S. M. Morroll, J. Kurth, L. Mao, R. Wing, D. Leister, P. Schulze-Lefert, and R. P. Wise (1999)
Genetics
153, 1929-1948
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- Production of an S RNase with Dual Specificity Suggests a Novel Hypothesis for the Generation of New S Alleles.
- D. P. Matton, D. T. Luu, Q. Xike, G. Laublin, M. O'Brien, O. Maes, D. Morse, and M. Cappadocia (1999)
PLANT CELL
11, 2087-2098
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- High gene density is conserved at syntenic loci of small and large grass genomes.
- C. Feuillet and B. Keller (1999)
PNAS
96, 8265-8270
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- Molecular Characterization of the Maize Rp1-D Rust Resistance Haplotype and Its Mutants.
- N. Collins, J. Drake, M. Ayliffe, Q. Sun, J. Ellis, S. Hulbert, and T. Pryor (1999)
PLANT CELL
11, 1365-1376
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- The Rx Gene from Potato Controls Separate Virus Resistance and Cell Death Responses.
- A. Bendahmane, K. Kanyuka, and D. C. Baulcombe (1999)
PLANT CELL
11, 781-792
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- Isolation of Ethylene-Insensitive Soybean Mutants That Are Altered in Pathogen Susceptibility and Gene-for-Gene Disease Resistance.
- T. Hoffman, J. S. Schmidt, X. Zheng, and A. F. Bent (1999)
Plant Physiology
119, 935-950
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- Diversity and molecular evolution of the RPS2 resistance gene in Arabidopsis thaliana.
- A. L. Caicedo, B. A. Schaal, and B. N. Kunkel (1999)
PNAS
96, 302-306
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- Suppressors of the Arabidopsis lsd5 Cell Death Mutation Identify Genes Involved in Regulating Disease Resistance Responses.
- J.-B. Morel and J. L. Dangl (1999)
Genetics
151, 305-319
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- Independent deletions of a pathogen-resistance gene in Brassica and Arabidopsis.
- M. R. Grant, J. M. McDowell, A. G. Sharpe, M. de Torres Zabala, D. J. Lydiate, and J. L. Dangl (1998)
PNAS
95, 15843-15848
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- The Arabidopsis thaliana RPM1 disease resistance gene product is a peripheral plasma membrane protein that is degraded coincident with the hypersensitive response.
- D. C. Boyes, J. Nam, and J. L. Dangl (1998)
PNAS
95, 15849-15854
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