Science 21 July 1995: Vol. 269. no. 5222, pp. 403 - 407 DOI: 10.1126/science.7618106

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Articles

MEK4 Function, Genistein Treatment, and Invasion of Human Prostate Cancer Cells.

L. Xu, Y. Ding, W. J. Catalona, X. J. Yang, W. F. Anderson, B. Jovanovic, K. Wellman, J. Killmer, X. Huang, K. A. Scheidt, et al. (2009)
J Natl Cancer Inst 101, 1141-1155
 |  Abstract »  |  Full Text »  |  PDF »

MAPK signaling pathways in the regulation of hematopoiesis.

C. R. Geest and P. J. Coffer (2009)
J. Leukoc. Biol. 86, 237-250
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}1-Adrenergic Receptor Stimulates Interleukin-6 Expression and Secretion through Both mRNA Stability and Transcriptional Regulation: Involvement of p38 Mitogen-Activated Protein Kinase and Nuclear Factor-{kappa}B.

D. M. Perez, R. S. Papay, and T. Shi (2009)
Mol. Pharmacol. 76, 144-152
 |  Abstract »  |  Full Text »  |  PDF »

Lot1 Is a Key Element of the Pituitary Adenylate Cyclase-activating Polypeptide (PACAP)/Cyclic AMP Pathway That Negatively Regulates Neuronal Precursor Proliferation.

T. Fila, S. Trazzi, C. Crochemore, R. Bartesaghi, and E. Ciani (2009)
J. Biol. Chem. 284, 15325-15338
 |  Abstract »  |  Full Text »  |  PDF »

Complexity in Transcription Control at the Activation Domain-Mediator Interface.

M. A. Balamotis, M. A. Pennella, J. L. Stevens, B. Wasylyk, A. S. Belmont, and A. J. Berk (2009)
Science Signaling 2, ra20
 |  Abstract »  |  Full Text »  |  PDF »

10-Formyltetrahydrofolate Dehydrogenase-Induced c-Jun-NH2-Kinase Pathways Diverge at the c-Jun-NH2-Kinase Substrate Level in Cells with Different p53 Status.

S. Ghose, N. V. Oleinik, N. I. Krupenko, and S. A. Krupenko (2009)
Mol. Cancer Res. 7, 99-107
 |  Abstract »  |  Full Text »  |  PDF »

The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia.

R M Thomas, J Kim, M P Revelo-Penafiel, R Angel, D W Dawson, and A M Lowy (2008)
Gut 57, 1555-1560
 |  Abstract »  |  Full Text »  |  PDF »

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6.

B. K. Pedersen and M. A. Febbraio (2008)
Physiol Rev 88, 1379-1406
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Regulation of EGR-1 by the Interleukin-1-JNK-MKK7-c-Jun Pathway.

E. Hoffmann, J. Ashouri, S. Wolter, A. Doerrie, O. Dittrich-Breiholz, H. Schneider, E. F. Wagner, J. Troppmair, N. Mackman, and M. Kracht (2008)
J. Biol. Chem. 283, 12120-12128
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipase D1 Plays a Key Role in TNF-{alpha} Signaling.

S. Sethu, G. Mendez-Corao, and A. J. Melendez (2008)
J. Immunol. 180, 6027-6034
 |  Abstract »  |  Full Text »  |  PDF »

Prostaglandin F2{alpha} Stimulates the Expression and Secretion of Transforming Growth Factor B1 Via Induction of the Early Growth Response 1 Gene (EGR1) in the Bovine Corpus Luteum.

X. Hou, E. W. Arvisais, C. Jiang, D.-b. Chen, S. K. Roy, J. L. Pate, T. R. Hansen, B. R. Rueda, and J. S. Davis (2008)
Mol. Endocrinol. 22, 403-414
 |  Abstract »  |  Full Text »  |  PDF »

Activated Protein C Decreases Tumor Necrosis Factor Related Apoptosis-Inducing Ligand by an EPCR- Independent Mechanism Involving Egr-1/Erk-1/2 Activation.

L. A. O'Brien, M. A. Richardson, S. F. Mehrbod, D. T. Berg, B. Gerlitz, A. Gupta, and B. W. Grinnell (2007)
Arterioscler Thromb Vasc Biol 27, 2634-2641
 |  Abstract »  |  Full Text »  |  PDF »

Late Endosomal Traffic of the Epidermal Growth Factor Receptor Ensures Spatial and Temporal Fidelity of Mitogen-activated Protein Kinase Signaling.

N. Taub, D. Teis, H. L. Ebner, M. W. Hess, and L. A. Huber (2007)
Mol. Biol. Cell 18, 4698-4710
 |  Abstract »  |  Full Text »  |  PDF »

Early growth response factor-1 in acute lung injury.

N. Ngiam, M. Post, and B. P. Kavanagh (2007)
Am J Physiol Lung Cell Mol Physiol 293, L1089-L1091
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Basic Fibroblast Growth Factor Activates the MAPK and NF{kappa}B Pathways That Converge on Elk-1 to Control Production of Matrix Metalloproteinase-13 by Human Adult Articular Chondrocytes.

P. Muddasani, J. C. Norman, M. Ellman, A. J. van Wijnen, and H.-J. Im (2007)
J. Biol. Chem. 282, 31409-31421
 |  Abstract »  |  Full Text »  |  PDF »

Rev7/MAD2B Links c-Jun N-Terminal Protein Kinase Pathway Signaling to Activation of the Transcription Factor Elk-1.

L. Zhang, S.-H. Yang, and A. D. Sharrocks (2007)
Mol. Cell. Biol. 27, 2861-2869
 |  Abstract »  |  Full Text »  |  PDF »

Controlled Release of Basic Fibroblast Growth Factor From Gelatin Hydrogel Sheet Improves Structural and Physiological Properties of Vein Graft in Rat.

T. Haraguchi, K. Okada, Y. Tabata, Y. Maniwa, Y. Hayashi, and Y. Okita (2007)
Arterioscler Thromb Vasc Biol 27, 548-555
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of the c-Jun N-Terminal Kinase-Mediated Mitochondrial Cell Death Pathway Restores Auditory Function in Sound-Exposed Animals.

J. Wang, J. Ruel, S. Ladrech, C. Bonny, T. R. van de Water, and J.-L. Puel (2007)
Mol. Pharmacol. 71, 654-666
 |  Abstract »  |  Full Text »  |  PDF »

Cell Fate Determination Factor DACH1 Inhibits c-Jun-induced Contact-independent Growth.

K. Wu, M. Liu, A. Li, H. Donninger, M. Rao, X. Jiao, M. P. Lisanti, A. Cvekl, M. Birrer, and R. G. Pestell (2007)
Mol. Biol. Cell 18, 755-767
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of Replicative Senescence of Diploid Human Cells by Nuclear ERK Signaling.

M. Tresini, A. Lorenzini, C. Torres, and V. J. Cristofalo (2007)
J. Biol. Chem. 282, 4136-4151
 |  Abstract »  |  Full Text »  |  PDF »

Genome-Wide Expression Profiling of the Retinoschisin-Deficient Retina in Early Postnatal Mouse Development.

A. Gehrig, T. Langmann, F. Horling, A. Janssen, M. Bonin, M. Walter, S. Poths, and B. H. F. Weber (2007)
Invest. Ophthalmol. Vis. Sci. 48, 891-900
 |  Abstract »  |  Full Text »  |  PDF »

TBP Is Differentially Regulated by c-Jun N-Terminal Kinase 1 (JNK1) and JNK2 through Elk-1, Controlling c-Jun Expression and Cell Proliferation.

S. Zhong, J. Fromm, and D. L. Johnson (2007)
Mol. Cell. Biol. 27, 54-64
 |  Abstract »  |  Full Text »  |  PDF »

Palytoxin: exploiting a novel skin tumor promoter to explore signal transduction and carcinogenesis.

E. V. Wattenberg (2007)
Am J Physiol Cell Physiol 292, C24-C32
 |  Abstract »  |  Full Text »  |  PDF »

Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases.

M. A. Bogoyevitch and B. Kobe (2006)
Microbiol. Mol. Biol. Rev. 70, 1061-1095
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the Gene Encoding Poly(ADP-ribose) Polymerase-1 Is Modulated by Fibronectin during Corneal Wound Healing..

K. Zaniolo, M.-E. Gingras, M. Audette, and S. L. Guerin (2006)
Invest. Ophthalmol. Vis. Sci. 47, 4199-4210
 |  Abstract »  |  Full Text »  |  PDF »

17beta-Estradiol, Genistein, and 4-Hydroxytamoxifen Induce the Proliferation of Thyroid Cancer Cells through the G Protein-Coupled Receptor GPR30.

A. Vivacqua, D. Bonofiglio, L. Albanito, A. Madeo, V. Rago, A. Carpino, A. M. Musti, D. Picard, S. Ando, and M. Maggiolini (2006)
Mol. Pharmacol. 70, 1414-1423
 |  Abstract »  |  Full Text »  |  PDF »

The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation.

J.-H. Chung, M. C. Ostrowski, T. Romigh, T. Minaguchi, K. A. Waite, and C. Eng (2006)
Hum. Mol. Genet. 15, 2553-2559
 |  Abstract »  |  Full Text »  |  PDF »

p300/Cyclic AMP-Responsive Element Binding-Binding Protein Mediates Transcriptional Coactivation by the CD28 T Cell Costimulatory Receptor.

S. L. Nandiwada, W. Li, R. Zhang, and D. L. Mueller (2006)
J. Immunol. 177, 401-413
 |  Abstract »  |  Full Text »  |  PDF »

1-Methoxy-Canthin-6-One Induces c-Jun NH2-Terminal Kinase-Dependent Apoptosis and Synergizes with Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Activity in Human Neoplastic Cells of Hematopoietic or Endodermal Origin..

M. Ammirante, R. Di Giacomo, L. De Martino, A. Rosati, M. Festa, A. Gentilella, M. C. Pascale, M. A. Belisario, A. Leone, M. Caterina Turco, et al. (2006)
Cancer Res. 66, 4385-4393
 |  Abstract »  |  Full Text »  |  PDF »

A Phosphatidylinositol 3-Kinase-regulated Akt-Independent Signaling Promotes Cigarette Smoke-induced FRA-1 Expression.

Q. Zhang, P. Adiseshaiah, D. V. Kalvakolanu, and S. P. Reddy (2006)
J. Biol. Chem. 281, 10174-10181
 |  Abstract »  |  Full Text »  |  PDF »

P38 MAP kinase mediates transforming growth factor-beta2 transcription in human keloid fibroblasts.

W. Xia, M. T. Longaker, and G. P. Yang (2006)
Am J Physiol Regulatory Integrative Comp Physiol 290, R501-R508
 |  Abstract »  |  Full Text »  |  PDF »

Activation of p-ERK1/2 by nicotine in pancreatic tumor cell line AR42J: effects on proliferation and secretion.

C. Bose, H. Zhang, K. B. Udupa, and P. Chowdhury (2005)
Am J Physiol Gastrointest Liver Physiol 289, G926-G934
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of the Transcriptional Activity of c-Fos by ERK: A NOVEL ROLE FOR THE PROLYL ISOMERASE PIN1.

P. Monje, J. Hernandez-Losa, R. J. Lyons, M. D. Castellone, and J. S. Gutkind (2005)
J. Biol. Chem. 280, 35081-35084
 |  Abstract »  |  Full Text »  |  PDF »

Gonadotropin-Releasing Hormone Induction of Extracellular-Signal Regulated Kinase Is Blocked by Inhibition of Calmodulin.

M. S. Roberson, S. P. Bliss, J. Xie, A. M. Navratil, T. A. Farmerie, M. W. Wolfe, and C. M. Clay (2005)
Mol. Endocrinol. 19, 2412-2423
 |  Abstract »  |  Full Text »  |  PDF »

EGF stimulates mesangial cell mitogenesis via PI3-kinase-mediated MAPK-dependent and AKT kinase-independent manner: involvement of c-fos and p27Kip1.

L. Mahimainathan, N. Ghosh-Choudhury, B. A. Venkatesan, R. S. Danda, and G. G. Choudhury (2005)
Am J Physiol Renal Physiol 289, F72-F82
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Carboxyl-terminal Tyrosines Modulates the Specificity of Sprouty-2 Inhibition of Different Signaling Pathways.

C. Rubin, Y. Zwang, N. Vaisman, D. Ron, and Y. Yarden (2005)
J. Biol. Chem. 280, 9735-9744
 |  Abstract »  |  Full Text »  |  PDF »

Loss of Net as Repressor Leads to Constitutive Increased c-fos Transcription in Cervical Cancer Cells.

J. van Riggelen, G. Buchwalter, U. Soto, J. De-Castro Arce, H. z. Hausen, B. Wasylyk, and F. Rosl (2005)
J. Biol. Chem. 280, 3286-3294
 |  Abstract »  |  Full Text »  |  PDF »

Coxsackievirus B3 Infection Induces cyr61 Activation via JNK To Mediate Cell Death.

S.-M. Kim, J.-H. Park, S.-K. Chung, J.-Y. Kim, H.-Y. Hwang, K.-C. Chung, I. Jo, S.-I. Park, and J.-H. Nam (2004)
J. Virol. 78, 13479-13488
 |  Abstract »  |  Full Text »  |  PDF »

Functional Mapping of the Auditory Midbrain during Mate Call Reception.

K. L. Hoke, S. S. Burmeister, R. D. Fernald, A. S. Rand, M. J. Ryan, and W. Wilczynski (2004)
J. Neurosci. 24, 11264-11272
 |  Abstract »  |  Full Text »  |  PDF »

Vav Transformation Requires Activation of Multiple GTPases and Regulation of Gene Expression.

T. R. Palmby, K. Abe, A. E. Karnoub, and C. J. Der (2004)
Mol. Cancer Res. 2, 702-711
 |  Abstract »  |  Full Text »  |  PDF »

Syndecan-4 Regulates ATF-2 Transcriptional Activity in a Rac1-dependent Manner.

S. Saoncella, E. Calautti, W. Neveu, and P. F. Goetinck (2004)
J. Biol. Chem. 279, 47172-47176
 |  Abstract »  |  Full Text »  |  PDF »

Mechanical stretch and progesterone differentially regulate activator protein-1 transcription factors in primary rat myometrial smooth muscle cells.

J. A. Mitchell, O. Shynlova, B. L. Langille, and S. J. Lye (2004)
Am J Physiol Endocrinol Metab 287, E439-E445
 |  Abstract »  |  Full Text »  |  PDF »

A Neuronal Isoform of Protein Kinase G Couples Mitogen-Activated Protein Kinase Nuclear Import to Axotomy-Induced Long-Term Hyperexcitability in Aplysia Sensory Neurons.

Y.-J. Sung, E. T. Walters, and R. T. Ambron (2004)
J. Neurosci. 24, 7583-7595
 |  Abstract »  |  Full Text »  |  PDF »

Sorting nexin 16 regulates EGF receptor trafficking by phosphatidylinositol-3-phosphate interaction with the Phox domain.

J. H. Choi, W.-P. Hong, M. J. Kim, J. H. Kim, S. H. Ryu, and P.-G. Suh (2004)
J. Cell Sci. 117, 4209-4218
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipase C-{gamma}1 is a guanine nucleotide exchange factor for dynamin-1 and enhances dynamin-1-dependent epidermal growth factor receptor endocytosis.

J. H. Choi, J. B. Park, S. S. Bae, S. Yun, H. S. Kim, W.-P. Hong, I.-S. Kim, J. H. Kim, M. Y. Han, S. H. Ryu, et al. (2004)
J. Cell Sci. 117, 3785-3795
 |  Abstract »  |  Full Text »  |  PDF »

ERK1/2 Associates with the c-Met-binding Domain of Growth Factor Receptor-bound Protein 2 (Grb2)-associated Binder-1 (Gab1): ROLE IN ERK1/2 AND EARLY GROWTH RESPONSE FACTOR-1 (Egr-1) NUCLEAR ACCUMULATION.

M. Osawa, S. Itoh, S. Ohta, Q. Huang, B. C. Berk, N.-L. Marmarosh, W. Che, B. Ding, C. Yan, and J.-i. Abe (2004)
J. Biol. Chem. 279, 29691-29699
 |  Abstract »  |  Full Text »  |  PDF »

Coordinate Signaling by Src and p38 Kinases in the Induction of Cortical Cataracts.

J. Zhou and A. S. Menko (2004)
Invest. Ophthalmol. Vis. Sci. 45, 2314-2323
 |  Abstract »  |  Full Text »  |  PDF »

A Linear Signal Transduction Pathway Involving Phosphatidylinositol 3-Kinase, Protein Kinase C{epsilon}, and MAPK in Mesangial Cells Regulates Interferon-{gamma}-induced STAT1{alpha} Transcriptional Activation.

G. G. Choudhury (2004)
J. Biol. Chem. 279, 27399-27409
 |  Abstract »  |  Full Text »  |  PDF »

Mitogen-activated protein kinase pathways and cardiac surgery.

T. A. Khan, C. Bianchi, M. Ruel, P. Voisine, and F. W. Sellke (2004)
J. Thorac. Cardiovasc. Surg. 127, 806-811
 |  Abstract »  |  Full Text »  |  PDF »

Altered Mitogen-Activated Protein Kinase Signal Transduction in Human Skin Fibroblasts During In Vitro Aging: Differential Expression of Low-Density Lipoprotein Receptor.

C. Bose, C. Bhuvaneswaran, and K. B. Udupa (2004)
J. Gerontol. A Biol. Sci. Med. Sci. 59, B126-135
 |  Abstract »  |  Full Text »  |  PDF »

Global Gene Expression Responses of Fission Yeast to Ionizing Radiation.

A. Watson, J. Mata, J. Bahler, A. Carr, and T. Humphrey (2004)
Mol. Biol. Cell 15, 851-860
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A Network of Immediate Early Gene Products Propagates Subtle Differences in Mitogen-Activated Protein Kinase Signal Amplitude and Duration.

L. O. Murphy, J. P. MacKeigan, and J. Blenis (2004)
Mol. Cell. Biol. 24, 144-153
 |  Abstract »  |  Full Text »  |  PDF »

Mice Deficient for the Ets Transcription Factor Elk-1 Show Normal Immune Responses and Mildly Impaired Neuronal Gene Activation.

F. Cesari, S. Brecht, K. Vintersten, L. G. Vuong, M. Hofmann, K. Klingel, J.-J. Schnorr, S. Arsenian, H. Schild, T. Herdegen, et al. (2004)
Mol. Cell. Biol. 24, 294-305
 |  Abstract »  |  Full Text »  |  PDF »

Dexamethasone Inhibits IL-12p40 Production in Lipopolysaccharide-Stimulated Human Monocytic Cells by Down-Regulating the Activity of c-Jun N-Terminal Kinase, the Activation Protein-1, and NF-{kappa}B Transcription Factors.

W. Ma, K. Gee, W. Lim, K. Chambers, J. B. Angel, M. Kozlowski, and A. Kumar (2004)
J. Immunol. 172, 318-330
 |  Abstract »  |  Full Text »  |  PDF »

p57KIP2 Modulates Stress-activated Signaling by Inhibiting c-Jun NH2-terminal Kinase/Stress-activated Protein Kinase.

T.-S. Chang, M. J. Kim, K. Ryoo, J. Park, S.-J. Eom, J. Shim, K. I. Nakayama, K. Nakayama, M. Tomita, K. Takahashi, et al. (2003)
J. Biol. Chem. 278, 48092-48098
 |  Abstract »  |  Full Text »  |  PDF »

TL1A-induced NF-{kappa}B Activation and c-IAP2 Production Prevent DR3-mediated Apoptosis in TF-1 Cells.

L. Wen, L. Zhuang, X. Luo, and P. Wei (2003)
J. Biol. Chem. 278, 39251-39258
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of the Carboxyl-Terminal Transactivation Domain of c-Fos by Extracellular Signal-Regulated Kinase Mediates the Transcriptional Activation of AP-1 and Cellular Transformation Induced by Platelet-Derived Growth Factor.

P. Monje, M. J. Marinissen, and J. S. Gutkind (2003)
Mol. Cell. Biol. 23, 7030-7043
 |  Abstract »  |  Full Text »  |  PDF »

The effect of RU486 on the gene expression profile in an endometrial explant model.

R.D. Catalano, A. Yanaihara, A.L. Evans, D. Rocha, A. Prentice, S. Saidi, C.G. Print, D.S. Charnock-Jones, A.M. Sharkey, and S.K. Smith (2003)
Mol. Hum. Reprod. 9, 465-473
 |  Abstract »  |  Full Text »  |  PDF »

Independent and Cooperative Activation of Chromosomal c-fos Promoter by STAT3.

E. Yang, L. Lerner, D. Besser, and J. E. Darnell Jr. (2003)
J. Biol. Chem. 278, 15794-15799
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Angiogenic Factor Cyr61 during Neuronal Cell Death via the Activation of c-Jun N-terminal Kinase and Serum Response Factor.

K. H. Kim, Y. K. Min, J.-H. Baik, L. F. Lau, B. Chaqour, and K. C. Chung (2003)
J. Biol. Chem. 278, 13847-13854
 |  Abstract »  |  Full Text »  |  PDF »

Mitogen-activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress.

K. J. Cowan and K. B. Storey (2003)
J. Exp. Biol. 206, 1107-1115
 |  Abstract »  |  Full Text »  |  PDF »

p38 Isoforms Have Opposite Effects on AP-1-dependent Transcription through Regulation of c-Jun. THE DETERMINANT ROLE OF THE ISOFORMS IN THE p38 MAPK SIGNAL SPECIFICITY.

R. Pramanik, X. Qi, S. Borowicz, D. Choubey, R. M. Schultz, J. Han, and G. Chen (2003)
J. Biol. Chem. 278, 4831-4839
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Myeloid Zinc Finger Protein 2A Transactivation Activity through Phosphorylation by Mitogen-activated Protein Kinases.

H. Ogawa, A. Murayama, S. Nagata, and R. Fukunaga (2003)
J. Biol. Chem. 278, 2921-2927
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Stress-Inducible Kinase Pathways by Tumorigenic Mutant p53.

Y. Ohiro, A. Usheva, S. Kobayashi, S. L. Duffy, R. Nantz, D. Gius, and N. Horikoshi (2003)
Mol. Cell. Biol. 23, 322-334
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Activation of SAPK/JNK Signaling by Protein Kinase Cdelta in Response to DNA Damage.

K. Yoshida, Y. Miki, and D. Kufe (2002)
J. Biol. Chem. 277, 48372-48378
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of CD44 Expression by Lipopolysaccharide (LPS) and TNF-{alpha} in Human Monocytic Cells: Distinct Involvement of c-Jun N-Terminal Kinase in LPS-Induced CD44 Expression.

K. Gee, W. Lim, W. Ma, D. Nandan, F. Diaz-Mitoma, M. Kozlowski, and A. Kumar (2002)
J. Immunol. 169, 5660-5672
 |  Abstract »  |  Full Text »  |  PDF »

Ras/MAPK Pathway Confers Basement Membrane Dependence upon Endoderm Differentiation of Embryonic Carcinoma Cells.

J. L. Smedberg, E. R. Smith, C. D. Capo-chichi, A. Frolov, D.-H. Yang, A. K. Godwin, and X.-X. Xu (2002)
J. Biol. Chem. 277, 40911-40918
 |  Abstract »  |  Full Text »  |  PDF »

Induction of the Mouse kappa -Opioid Receptor Gene by Retinoic Acid in P19 Cells.

J. Li, S. W. Park, H. H. Loh, and L.-N. Wei (2002)
J. Biol. Chem. 277, 39967-39972
 |  Abstract »  |  Full Text »  |  PDF »

Negative regulatory role of overexpression of PLC{gamma}1 in the expression of early growth response 1 gene in rat 3Y1 fibroblasts.

S. Y. SHIN, J. KO, J.-S. CHANG, D. S. MIN, C. CHOI, S. S. BAE, M. J. KIM, D. S. HYUN, J.-H. KIM, M. Y. HAN, et al. (2002)
FASEB J 16, 1504-1514
 |  Abstract »  |  Full Text »  |  PDF »

Mitogen-activated protein kinases regulate HO-1 gene transcription after ischemia-reperfusion lung injury.

X. Zhang, E. L. Bedard, R. Potter, R. Zhong, J. Alam, A. M. K. Choi, and P. J. Lee (2002)
Am J Physiol Lung Cell Mol Physiol 283, L815-L829
 |  Abstract »  |  Full Text »  |  PDF »

Activation of second messenger pathways in alveolar macrophages by endotoxin.

M.M. Monick and G.W. Hunninghake (2002)
Eur. Respir. J. 20, 210-222
 |  Abstract »  |  Full Text »  |  PDF »

Role of Raf-1 and FAK in cell density-dependent regulation of integrin-dependent activation of MAP kinase.

L. Zhang, M. Bewick, and R. M. Lafrenie (2002)
Carcinogenesis 23, 1251-1258
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of c-Abl with STI571 Attenuates Stress-Activated Protein Kinase Activation and Apoptosis in the Cellular Response to 1-beta -D-Arabinofuranosylcytosine.

D. Raina, N. Mishra, S. Kumar, S. Kharbanda, S. Saxena, and D. Kufe (2002)
Mol. Pharmacol. 61, 1489-1495
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone Inhibits c-Jun N-Terminal Kinase Activity in Rat Osteoblastic Cells by a Protein Kinase A-Dependent Pathway.

T. A. Doggett, J. T. Swarthout, S. C. Jefcoat Jr., D. Wilhelm, A. Dieckmann, P. Angel, and N. C. Partridge (2002)
Endocrinology 143, 1880-1888
 |  Abstract »  |  Full Text »  |  PDF »

Role of Regulatory Elements and the MAPK/ERK or p38 MAPK Pathways for Activation of Human Cytomegalovirus Gene Expression.

J. Chen and M. F. Stinski (2002)
J. Virol. 76, 4873-4885
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Role of p38 and c-Jun N-Terminal Kinases in IL-10-Dependent and IL-10-Independent Regulation of the Costimulatory Molecule B7.2 in Lipopolysaccharide-Stimulated Human Monocytic Cells.

W. Lim, W. Ma, K. Gee, S. Aucoin, D. Nandan, F. Diaz-Mitoma, M. Kozlowski, and A. Kumar (2002)
J. Immunol. 168, 1759-1769
 |  Abstract »  |  Full Text »  |  PDF »

Src Autophosphorylation is an Early Event in Pressure-Mediated Signaling Pathways in Isolated Resistance Arteries.

D. C. Rice, A. D. Dobrian, S. D. Schriver, and R. L. Prewitt (2002)
Hypertension 39, 502-507
 |  Abstract »  |  Full Text »  |  PDF »

Transactivation of Fra-1 and Consequent Activation of AP-1 Occur Extracellular Signal-Regulated Kinase Dependently.

M. R. Young, R. Nair, N. Bucheimer, P. Tulsian, N. Brown, C. Chapp, T.-C. Hsu, and N. H. Colburn (2002)
Mol. Cell. Biol. 22, 587-598
 |  Abstract »  |  Full Text »  |  PDF »

Cell adhesion differentially regulates the nucleocytoplasmic distribution of active MAP kinases.

A. E. Aplin, B. P. Hogan, J. Tomeu, and R. L. Juliano (2002)
J. Cell Sci. 115, 2781-2790
 |  Abstract »  |  Full Text »  |  PDF »

Dominant Negative Mutant of c-Jun Inhibits Cardiomyocyte Hypertrophy Induced by Endothelin 1 and Phenylephrine.

T. Omura, M. Yoshiyama, K. Yoshida, Y. Nakamura, S. Kim, H. Iwao, K. Takeuchi, and J. Yoshikawa (2002)
Hypertension 39, 81-86
 |  Abstract »  |  Full Text »  |  PDF »

Transforming Growth Factor-beta Inhibition of Insulin-like Growth Factor-binding Protein-5 Synthesis in Skeletal Muscle Cells Involves a c-Jun N-terminal Kinase-dependent Pathway.

S. Rousse, F. Lallemand, D. Montarras, C. Pinset, A. Mazars, C. Prunier, A. Atfi, and C. Dubois (2001)
J. Biol. Chem. 276, 46961-46967
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Elk-1, an Ets transcription factor, by glucose and EGF treatment of insulinoma cells.

E. Bernal-Mizrachi, W. Wen, S. Srinivasan, A. Klenk, D. Cohen, and M. A. Permutt (2001)
Am J Physiol Endocrinol Metab 281, E1286-E1299
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation Is Involved in the Activation of Metal-regulatory Transcription Factor 1 in Response to Metal Ions.

O. LaRochelle, V. Gagne, J. Charron, J.-W. Soh, and C. Seguin (2001)
J. Biol. Chem. 276, 41879-41888
 |  Abstract »  |  Full Text »  |  PDF »

Activation of {beta}2-Adrenoceptor Prevents Shiga Toxin 2-Induced TNF-{alpha} Gene Transcription.

A. NAKAMURA, E. J. JOHNS, A. IMAIZUMI, Y. YANAGAWA, and T. KOHSAKA (2001)
J. Am. Soc. Nephrol. 12, 2288-2299
 |  Abstract »  |  Full Text »  |  PDF »

Early Postnatal Cardiac Changes and Premature Death in Transgenic Mice Overexpressing a Mutant Form of Serum Response Factor.

X. Zhang, J. Chai, G. Azhar, P. Sheridan, A. M. Borras, M. C. Furr, K. Khrapko, J. Lawitts, R. P. Misra, and J. Y. Wei (2001)
J. Biol. Chem. 276, 40033-40040
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Mitogen-Activated Protein Kinase Phosphatase Is an Important Negative Regulator of Lipopolysaccharide-Mediated c-Jun N-Terminal Kinase Activation in Mouse Macrophage Cell Lines.

T. Matsuguchi, T. Musikacharoen, T. R. Johnson, A. S. Kraft, and Y. Yoshikai (2001)
Mol. Cell. Biol. 21, 6999-7009
 |  Abstract »  |  Full Text »  |  PDF »

ERK2- and p90Rsk2-dependent Pathways Regulate the CCAAT/Enhancer-binding Protein-beta Interaction with Serum Response Factor.

M. Hanlon, T. W. Sturgill, and L. Sealy (2001)
J. Biol. Chem. 276, 38449-38456
 |  Abstract »  |  Full Text »  |  PDF »

Fucosyltransferases: structure/function studies.

T. de Vries, R. M.A. Knegtel, E. H. Holmes, and B. A. Macher (2001)
Glycobiology 11, 119R-128R
 |  Abstract »  |  Full Text »  |  PDF »

Essential role for extracellular Ca2+ in JNK activation by mechanical stretch in bladder smooth muscle cells.

N. Kushida, Y. Kabuyama, O. Yamaguchi, and Y. Homma (2001)
Am J Physiol Cell Physiol 281, C1165-C1172
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the actin cytoskeleton regulates cytokine-induced iNOS expression.

C. Zeng and A. R. Morrison (2001)
Am J Physiol Cell Physiol 281, C932-C940
 |  Abstract »  |  Full Text »  |  PDF »

Inducible Expression of the Megakarocyte-specific Gene Glycoprotein IX Is Mediated through an Ets Binding Site and Involves Upstream Activation of Extracellular Signal-regulated Kinase.

M. Eisbacher, L. M. Khachigian, T. H. Khin, M. L. Holmes, and B. H. Chong (2001)
Cell Growth Differ. 12, 435-445
 |  Abstract »  |  Full Text »  |  PDF »

CD28 Signaling Augments Elk-1-Dependent Transcription at the c-fos Gene During Antigen Stimulation.

W. Li, C. D. Whaley, J. L. Bonnevier, A. Mondino, M. E. Martin, K. M. Aagaard-Tillery, and D. L. Mueller (2001)
J. Immunol. 167, 827-835
 |  Abstract »  |  Full Text »  |  PDF »

Complex Functions of AP-1 Transcription Factors in Differentiation and Survival of PC12 Cells.

S. Leppa, M. Eriksson, R. Saffrich, W. Ansorge, and D. Bohmann (2001)
Mol. Cell. Biol. 21, 4369-4378
 |  Abstract »  |  Full Text »  |  PDF »

AP-1 Repressor Protein JDP-2: Inhibition of UV-Mediated Apoptosis through p53 Down-Regulation.

F. Piu, A. Aronheim, S. Katz, and M. Karin (2001)
Mol. Cell. Biol. 21, 3012-3024
 |  Abstract »  |  Full Text »

Organ-specific Activation of Activator Protien-1 in Transgenic Mice by 12-O-Tetradecanoylphorbol-13-acetate with Different Administration Methods.

S. Zhong, J. A. Quealy, A. M. Bode, M. Nomura, A. Kaji, W.-Y. Ma, and Z. Dong (2001)
Cancer Res. 61, 4084-4091
 |  Abstract »  |  Full Text »

Ceramide Inhibits Lipopolysaccharide-Mediated Nitric Oxide Synthase and Cyclooxygenase-2 Induction in Macrophages: Effects on Protein Kinases and Transcription Factors.

Y.-W. Hsu, K.-H. Chi, W.-C. Huang, and W.-W. Lin (2001)
J. Immunol. 166, 5388-5397
 |  Abstract »  |  Full Text »  |  PDF »

Integrin-Mediated Adhesion Regulates ERK Nuclear Translocation and Phosphorylation of Elk-1.

A. E. Aplin, S. A. Stewart, R. K. Assoian, and R.L. Juliano (2001)
J. Cell Biol. 153, 273-282
 |  Abstract »  |  Full Text »  |  PDF »

Zn2+ Induces Stimulation of the c-Jun N-Terminal Kinase Signaling Pathway through Phosphoinositide 3-Kinase.

S.-J. Eom, E. Y. Kim, J. E. Lee, H. J. Kang, J. Shim, S. U. Kim, B. J. Gwag, and E.-J. Choi (2001)
Mol. Pharmacol. 59, 981-986
 |  Abstract »  |  Full Text »

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation.

J. M. Kyriakis and J. Avruch (2001)
Physiol Rev 81, 807-869
 |  Abstract »  |  Full Text »  |  PDF »

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