Science 14 July 1995: Vol. 269. no. 5221, pp. 234 - 238 DOI: 10.1126/science.7618085

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Articles

Role of Bone Marrow-Derived Cells in the Genetic Control of Restenosis.

N. Langwieser, J. B.K. Schwarz, C. Reichenbacher, B. Stemmer, S. Massberg, N. N. Langwieser, and D. Zohlnhofer (2009)
Arterioscler Thromb Vasc Biol 29, 1551-1557
 |  Abstract »  |  Full Text »  |  PDF »

Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis.

N. Jin, S.-N. Cho, M. G. Raso, I. Wistuba, Y. Smith, Y. Yang, J. M. Kurie, R. Yen, C. M. Evans, T. Ludwig, et al. (2009)
Development 136, 3347-3356
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Placental and Embryonic Growth Restriction in Mice With Reduced Function Epidermal Growth Factor Receptor Alleles.

J. Dackor, K. M. Caron, and D. W. Threadgill (2009)
Genetics 183, 207-218
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Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice.

C. J. Barrick, R. B. Roberts, M. Rojas, N. M. Rajamannan, C. B. Suitt, K. D. O'Brien, S. S. Smyth, and D. W. Threadgill (2009)
Am J Physiol Heart Circ Physiol 297, H65-H75
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Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB-EGF and TGF-{alpha}.

Y. Wang, B. S. Maciejewski, D. Soto-Reyes, H.-S. Lee, D. Warburton, and J. Sanchez-Esteban (2009)
J. Physiol. 587, 1739-1753
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Potential for Molecularly Targeted Therapy against Epidermal Growth Factor Receptor Ligands.

S. MIYAMOTO, T. FUKAMI, H. YAGI, M. KUROKI, and F. YOTSUMOTO (2009)
Anticancer Res 29, 823-830
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Conditional Inactivation of TACE by a Sox9 Promoter Leads to Osteoporosis and Increased Granulopoiesis via Dysregulation of IL-17 and G-CSF.

K. Horiuchi, T. Kimura, T. Miyamoto, K. Miyamoto, H. Akiyama, H. Takaishi, H. Morioka, T. Nakamura, Y. Okada, C. P. Blobel, et al. (2009)
J. Immunol. 182, 2093-2101
 |  Abstract »  |  Full Text »  |  PDF »

Human ESC-derived Neural Rosettes and Neural Stem Cell Progression.

Y. Elkabetz and L. Studer (2009)
Cold Spring Harb Symp Quant Biol
 |  Abstract »  |  PDF »

Transient Receptor Potential Type Vanilloid 1 Suppresses Skin Carcinogenesis.

A. M. Bode, Y.-Y. Cho, D. Zheng, F. Zhu, M. E. Ericson, W.-Y. Ma, K. Yao, and Z. Dong (2009)
Cancer Res. 69, 905-913
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency of TNF{alpha} Converting Enzyme (TACE/ADAM17) Causes a Lean, Hypermetabolic Phenotype in Mice.

R. W. Gelling, W. Yan, S. Al-Noori, A. Pardini, G. J. Morton, K. Ogimoto, M. W. Schwartz, and P. J. Dempsey (2008)
Endocrinology 149, 6053-6064
 |  Abstract »  |  Full Text »  |  PDF »

GPR48 Regulates Epithelial Cell Proliferation and Migration by Activating EGFR during Eyelid Development.

C. Jin, F. Yin, M. Lin, H. Li, Z. Wang, J. Weng, M. Liu, X. Da Dong, J. Qu, and L. Tu (2008)
Invest. Ophthalmol. Vis. Sci. 49, 4245-4253
 |  Abstract »  |  Full Text »  |  PDF »

Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction.

V. Rajagopalan, I. H. Zucker, J. A. Jones, M. Carlson, and Y. J. Ma (2008)
Am J Physiol Heart Circ Physiol 295, H543-H554
 |  Abstract »  |  Full Text »  |  PDF »

Beyond Wavy Hairs: The Epidermal Growth Factor Receptor and Its Ligands in Skin Biology and Pathology.

M. R. Schneider, S. Werner, R. Paus, and E. Wolf (2008)
Am. J. Pathol. 173, 14-24
 |  Abstract »  |  Full Text »  |  PDF »

Absence of LPA1 Signaling Results in Defective Cortical Development.

G. Estivill-Torrus, P. Llebrez-Zayas, E. Matas-Rico, L. Santin, C. Pedraza, I. De Diego, I. Del Arco, P. Fernandez-Llebrez, J. Chun, and F. R. De Fonseca (2008)
Cereb Cortex 18, 938-950
 |  Abstract »  |  Full Text »  |  PDF »

ErbB4 deletion leads to changes in lung function and structure similar to bronchopulmonary dysplasia.

E. Purevdorj, K. Zscheppang, H. G. Hoymann, A. Braun, D. von Mayersbach, M.-J. Brinkhaus, A. Schmiedl, and C. E. L. Dammann (2008)
Am J Physiol Lung Cell Mol Physiol 294, L516-L522
 |  Abstract »  |  Full Text »  |  PDF »

Nucleotide P2Y1 receptor regulates EGF receptor mitogenic signaling and expression in epithelial cells.

S. Buvinic, M. Bravo-Zehnder, J. L. Boyer, J. P. Huidobro-Toro, and A. Gonzalez (2007)
J. Cell Sci. 120, 4289-4301
 |  Abstract »  |  Full Text »  |  PDF »

The EGF receptor is required for efficient liver regeneration.

A. Natarajan, B. Wagner, and M. Sibilia (2007)
PNAS 104, 17081-17086
 |  Abstract »  |  Full Text »  |  PDF »

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.

U. Schaeper, R. Vogel, J. Chmielowiec, J. Huelsken, M. Rosario, and W. Birchmeier (2007)
PNAS 104, 15376-15381
 |  Abstract »  |  Full Text »  |  PDF »

Differential ErbB1 Signaling in Squamous Cell versus Basal Cell Carcinoma of the Skin.

L. Rittie, S. Kansra, S. W. Stoll, Y. Li, J. E. Gudjonsson, Y. Shao, L. E. Michael, G. J. Fisher, T. M. Johnson, and J. T. Elder (2007)
Am. J. Pathol. 170, 2089-2099
 |  Abstract »  |  Full Text »  |  PDF »

Early Embryonic Lethality of Mice Lacking the Essential Protein SNEV.

K. Fortschegger, B. Wagner, R. Voglauer, H. Katinger, M. Sibilia, and J. Grillari (2007)
Mol. Cell. Biol. 27, 3123-3130
 |  Abstract »  |  Full Text »  |  PDF »

Astroglial Cells in Development, Regeneration, and Repair.

F. M. Vaccarino, D. M. Fagel, Y. Ganat, M. E. Maragnoli, L. R. Ment, Y. Ohkubo, M. L. Schwartz, J. Silbereis, and K. M. Smith (2007)
Neuroscientist 13, 173-185
 |  Abstract »  |  PDF »

Non-Cell Autonomous Expression of TNF-{alpha}-Converting Enzyme ADAM17 Is Required for Normal Lymphocyte Development.

N. Li, K. Boyd, P. J. Dempsey, and D. A. A. Vignali (2007)
J. Immunol. 178, 4214-4221
 |  Abstract »  |  Full Text »  |  PDF »

Pregnancy in the Brown Norway Rat: A Model for Investigating the Genetics of Placentation.

T. Konno, L. A. Rempel, J. A. Arroyo, and M. J. Soares (2007)
Biol Reprod 76, 709-718
 |  Abstract »  |  Full Text »  |  PDF »

Luteinizing Hormone-Dependent Activation of the Epidermal Growth Factor Network Is Essential for Ovulation.

M. Hsieh, D. Lee, S. Panigone, K. Horner, R. Chen, A. Theologis, D. C. Lee, D. W. Threadgill, and M. Conti (2007)
Mol. Cell. Biol. 27, 1914-1924
 |  Abstract »  |  Full Text »  |  PDF »

Somatic Excision Demonstrates that c-Jun Induces Cellular Migration and Invasion through Induction of Stem Cell Factor.

S. Katiyar, X. Jiao, E. Wagner, M. P. Lisanti, and R. G. Pestell (2007)
Mol. Cell. Biol. 27, 1356-1369
 |  Abstract »  |  Full Text »  |  PDF »

p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis.

D. Teis, N. Taub, R. Kurzbauer, D. Hilber, M. E. de Araujo, M. Erlacher, M. Offterdinger, A. Villunger, S. Geley, G. Bohn, et al. (2006)
J. Cell Biol. 175, 861-868
 |  Abstract »  |  Full Text »  |  PDF »

Diacylglycerol kinase {delta} regulates protein kinase C and epidermal growth factor receptor signaling.

T. Crotty, J. Cai, F. Sakane, A. Taketomi, S. M. Prescott, and M. K. Topham (2006)
PNAS 103, 15485-15490
 |  Abstract »  |  Full Text »  |  PDF »

Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes..

M. Kasper, H. Schnidar, G. W. Neill, M. Hanneder, S. Klingler, L. Blaas, C. Schmid, C. Hauser-Kronberger, G. Regl, M. P. Philpott, et al. (2006)
Mol. Cell. Biol. 26, 6283-6298
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal growth factor receptor activation: an upstream signal for transition of quiescent astrocytes into reactive astrocytes after neural injury..

B. Liu, H. Chen, T. G. Johns, and A. H. Neufeld (2006)
J. Neurosci. 26, 7532-7540
 |  Abstract »  |  Full Text »  |  PDF »

Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor.

T. B. El-Abaseri, S. Putta, and L. A. Hansen (2006)
Carcinogenesis 27, 225-231
 |  Abstract »  |  Full Text »  |  PDF »

AP-2{alpha}: a regulator of EGF receptor signaling and proliferation in skin epidermis.

X. Wang, D. Bolotin, D. H. Chu, L. Polak, T. Williams, and E. Fuchs (2006)
J. Cell Biol. 172, 409-421
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of EGFR and ErbB2 by the Novel Dual EGFR and ErbB2 Tyrosine Kinase Inhibitor GW572016 Sensitizes Human Colon Carcinoma GEO Cells to Apoptosis.

Y. Zhou, S. Li, Y. P. Hu, J. Wang, J. Hauser, A. N. Conway, M. A. Vinci, L. Humphrey, E. Zborowska, J. K.V. Willson, et al. (2006)
Cancer Res. 66, 404-411
 |  Abstract »  |  Full Text »  |  PDF »

HB-EGF promotes epithelial cell migration in eyelid development.

N. Mine, R. Iwamoto, and E. Mekada (2005)
Development 132, 4317-4326
 |  Abstract »  |  Full Text »  |  PDF »

Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin.

M. D. Sternlicht, S. W. Sunnarborg, H. Kouros-Mehr, Y. Yu, D. C. Lee, and Z. Werb (2005)
Development 132, 3923-3933
 |  Abstract »  |  Full Text »  |  PDF »

ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo.

D. Thumkeo, Y. Shimizu, S. Sakamoto, S. Yamada, and S. Narumiya (2005)
Genes Cells 10, 825-834
 |  Abstract »  |  Full Text »  |  PDF »

A Structural Model for the Membrane-bound Form of the Juxtamembrane Domain of the Epidermal Growth Factor Receptor.

K. Choowongkomon, C. R. Carlin, and F. D. Sonnichsen (2005)
J. Biol. Chem. 280, 24043-24052
 |  Abstract »  |  Full Text »  |  PDF »

Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing.

Y. Shirakata, R. Kimura, D. Nanba, R. Iwamoto, S. Tokumaru, C. Morimoto, K. Yokota, M. Nakamura, K. Sayama, E. Mekada, et al. (2005)
J. Cell Sci. 118, 2363-2370
 |  Abstract »  |  Full Text »  |  PDF »

The Membrane-anchoring Domain of Epidermal Growth Factor Receptor Ligands Dictates Their Ability to Operate in Juxtacrine Mode.

J. Dong, L. K. Opresko, W. Chrisler, G. Orr, R. D. Quesenberry, D. A. Lauffenburger, and H. S. Wiley (2005)
Mol. Biol. Cell 16, 2984-2998
 |  Abstract »  |  Full Text »  |  PDF »

Dynamic Assembly of the Urokinase-type Plasminogen Activator Signaling Receptor Complex Determines the Mitogenic Activity of Urokinase-type Plasminogen Activator.

M. Jo, K. S. Thomas, N. Marozkina, T. J. Amin, C. M. Silva, S. J. Parsons, and S. L. Gonias (2005)
J. Biol. Chem. 280, 17449-17457
 |  Abstract »  |  Full Text »  |  PDF »

ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles.

Y. Shimizu, D. Thumkeo, J. Keel, T. Ishizaki, H. Oshima, M. Oshima, Y. Noda, F. Matsumura, M. M. Taketo, and S. Narumiya (2005)
J. Cell Biol. 168, 941-953
 |  Abstract »  |  Full Text »  |  PDF »

Combined Targeting of the Estrogen Receptor and the Epidermal Growth Factor Receptor in Non-Small Cell Lung Cancer Shows Enhanced Antiproliferative Effects.

L. P. Stabile, J. S. Lyker, C. T. Gubish, W. Zhang, J. R. Grandis, and J. M. Siegfried (2005)
Cancer Res. 65, 1459-1470
 |  Abstract »  |  Full Text »  |  PDF »

Gefitinib ("Iressa", ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses Breast Cancer Resistance Protein/ABCG2-Mediated Drug Resistance.

Y. Nakamura, M. Oka, H. Soda, K. Shiozawa, M. Yoshikawa, A. Itoh, Y. Ikegami, J. Tsurutani, K. Nakatomi, T. Kitazaki, et al. (2005)
Cancer Res. 65, 1541-1546
 |  Abstract »  |  Full Text »  |  PDF »

Myelinogenesis and Axonal Recognition by Oligodendrocytes in Brain Are Uncoupled in Olig1-Null Mice.

M. Xin, T. Yue, Z. Ma, F.-f. Wu, A. Gow, and Q. R. Lu (2005)
J. Neurosci. 25, 1354-1365
 |  Abstract »  |  Full Text »  |  PDF »

Amphiregulin Is a Novel Growth Factor Involved in Normal Bone Development and in the Cellular Response to Parathyroid Hormone Stimulation.

L. Qin, J. Tamasi, L. Raggatt, X. Li, J. H. M. Feyen, D. C. Lee, E. DiCicco-Bloom, and N. C. Partridge (2005)
J. Biol. Chem. 280, 3974-3981
 |  Abstract »  |  Full Text »  |  PDF »

ADAM10 Mediates Ectodomain Shedding of the Betacellulin Precursor Activated by p-Aminophenylmercuric Acetate and Extracellular Calcium Influx.

M. P. Sanderson, S. N. Erickson, P. J. Gough, K. J. Garton, P. T. Wille, E. W. Raines, A. J. Dunbar, and P. J. Dempsey (2005)
J. Biol. Chem. 280, 1826-1837
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal Growth Factor Receptor-deficient Mice Have Delayed Primary Endochondral Ossification Because of Defective Osteoclast Recruitment.

K. Wang, H. Yamamoto, J. R. Chin, Z. Werb, and T. H. Vu (2004)
J. Biol. Chem. 279, 53848-53856
 |  Abstract »  |  Full Text »  |  PDF »

Embryo-Uterine Interactions via the Neuregulin Family of Growth Factors During Implantation in the Mouse.

N. Brown, K. Deb, B. C. Paria, S. K. Das, and J. Reese (2004)
Biol Reprod 71, 2003-2011
 |  Abstract »  |  Full Text »  |  PDF »

Epiregulin Is Not Essential for Development of Intestinal Tumors but Is Required for Protection from Intestinal Damage.

D. Lee, R. S. Pearsall, S. Das, S. K. Dey, V. L. Godfrey, and D. W. Threadgill (2004)
Mol. Cell. Biol. 24, 8907-8916
 |  Abstract »  |  Full Text »  |  PDF »

Targeted Disruption of the Protein Kinase SGK3/CISK Impairs Postnatal Hair Follicle Development.

J. A. McCormick, Y. Feng, K. Dawson, M. J. Behne, B. Yu, J. Wang, A. W. Wyatt, G. Henke, F. Grahammer, T. M. Mauro, et al. (2004)
Mol. Biol. Cell 15, 4278-4288
 |  Abstract »  |  Full Text »  |  PDF »

Phenotypic Variation Resulting From a Deficiency of Epidermal Growth Factor Receptor in Mice Is Caused by Extensive Genetic Heterogeneity That Can Be Genetically and Molecularly Partitioned.

K. E. Strunk, V. Amann, and D. W. Threadgill (2004)
Genetics 167, 1821-1832
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Mechanisms Determine the Patterns of Differential Activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by Receptors for Growth Factors or Antigen.

A. Ehrhardt, M. D. David, G. R. A. Ehrhardt, and J. W. Schrader (2004)
Mol. Cell. Biol. 24, 6311-6323
 |  Abstract »  |  Full Text »  |  PDF »

Selective Roles for Tumor Necrosis Factor {alpha}-converting Enzyme/ADAM17 in the Shedding of the Epidermal Growth Factor Receptor Ligand Family: THE JUXTAMEMBRANE STALK DETERMINES CLEAVAGE EFFICIENCY.

C. L. Hinkle, S. W. Sunnarborg, D. Loiselle, C. E. Parker, M. Stevenson, W. E. Russell, and D. C. Lee (2004)
J. Biol. Chem. 279, 24179-24188
 |  Abstract »  |  Full Text »  |  PDF »

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.

U. Sahin, G. Weskamp, K. Kelly, H.-M. Zhou, S. Higashiyama, J. Peschon, D. Hartmann, P. Saftig, and C. P. Blobel (2004)
J. Cell Biol. 164, 769-779
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Second egfr Gene in Xiphophorus Uncovers an Expansion of the Epidermal Growth Factor Receptor Family in Fish.

A. Gomez, J.-N. Volff, U. Hornung, M. Schartl, and C. Wellbrock (2004)
Mol. Biol. Evol. 21, 266-275
 |  Abstract »  |  Full Text »  |  PDF »

Mechanical Stretch Induces Fetal Type II Cell Differentiation Via an Epidermal Growth Factor Receptor-Extracellular-Regulated Protein Kinase Signaling Pathway.

J. Sanchez-Esteban, Y. Wang, P. A. Gruppuso, and L. P. Rubin (2004)
Am. J. Respir. Cell Mol. Biol. 30, 76-83
 |  Abstract »  |  Full Text »  |  PDF »

Velvet, a Dominant Egfr Mutation That Causes Wavy Hair and Defective Eyelid Development in Mice.

X. Du, K. Tabeta, K. Hoebe, H. Liu, N. Mann, S. Mudd, K. Crozat, S. Sovath, X. Gong, and B. Beutler (2004)
Genetics 166, 331-340
 |  Abstract »  |  Full Text »  |  PDF »

Small-Molecule Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.

M. L. Janmaat and G. Giaccone (2003)
Oncologist 8, 576-586
 |  Abstract »  |  Full Text »  |  PDF »

Cbl-3-Deficient Mice Exhibit Normal Epithelial Development.

E. K. Griffiths, O. Sanchez, P. Mill, C. Krawczyk, C. V. Hojilla, E. Rubin, M. M. Nau, R. Khokha, S. Lipkowitz, C.-c. Hui, et al. (2003)
Mol. Cell. Biol. 23, 7708-7718
 |  Abstract »  |  Full Text »  |  PDF »

Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart.

M. Sibilia, B. Wagner, A. Hoebertz, C. Elliott, S. Marino, W. Jochum, and E. F. Wagner (2003)
Development 130, 4515-4525
 |  Abstract »  |  Full Text »  |  PDF »

Spatial and temporal patterns of ERK signaling during mouse embryogenesis.

L. B. Corson, Y. Yamanaka, K.-M. V. Lai, and J. Rossant (2003)
Development 130, 4527-4537
 |  Abstract »  |  Full Text »  |  PDF »

Role of extracellular subdomains of p185c-neu and the epidermal growth factor receptor in ligand-independent association and transactivation.

T. Kumagai, M. Katsumata, A. Hasegawa, K. Furuuchi, T. Funakoshi, I. Kawase, and M. I. Greene (2003)
PNAS 100, 9220-9225
 |  Abstract »  |  Full Text »  |  PDF »

Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality.

H. Tidcombe, A. Jackson-Fisher, K. Mathers, D. F. Stern, M. Gassmann, and J. P. Golding (2003)
PNAS 100, 8281-8286
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle.

K. K. L. Mak and S. Y. Chan (2003)
J. Biol. Chem. 278, 26120-26126
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Wound Healing by Growth Factors and Cytokines.

S. WERNER and R. GROSE (2003)
Physiol Rev 83, 835-870
 |  Abstract »  |  Full Text »  |  PDF »

Cell-specific and developmental expression of phospholipase C-gamma and diacylglycerol in fetal lung.

S. M. Ramadurai, W.-Y. Chen, G. B. Yerozolimsky, M. Zagami, C. E. L. Dammann, and H. C. Nielsen (2003)
Am J Physiol Lung Cell Mol Physiol 284, L808-L816
 |  Abstract »  |  Full Text »  |  PDF »

Mutation of Threonine 766 in the Epidermal Growth Factor Receptor Reveals a Hotspot for Resistance Formation against Selective Tyrosine Kinase Inhibitors.

S. Blencke, A. Ullrich, and H. Daub (2003)
J. Biol. Chem. 278, 15435-15440
 |  Abstract »  |  Full Text »  |  PDF »

Downregulation of the Epidermal Growth Factor Receptor by Human Cytomegalovirus Infection in Human Fetal Lung Fibroblasts.

T. Beutler, C. Hoflich, P. A. Stevens, D. H. Kruger, and S. Prosch (2003)
Am. J. Respir. Cell Mol. Biol. 28, 86-94
 |  Abstract »  |  Full Text »  |  PDF »

EGF and TGF-{alpha} Expression Influence the Developmental Toxicity of TCDD: Dose Response and AhR Phenotype in EGF, TGF-{alpha}, and EGF + TGF-{alpha} Knockout Mice.

B. D. Abbott, A. R. Buckalew, M. J. DeVito, D. Ross, P. L. Bryant, and J. E. Schmid (2003)
Toxicol. Sci. 71, 84-95
 |  Abstract »  |  Full Text »  |  PDF »

The ADAMs family of metalloproteases: multidomain proteins with multiple functions.

D. F. Seals and S. A. Courtneidge (2003)
Genes & Dev. 17, 7-30
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Increased Expression of Epidermal Growth Factor Receptor Induces Sequestration of Extracellular Signal-Related Kinases and Selective Attenuation of Specific Epidermal Growth Factor-Mediated Signal Transduction Pathways.

A. A. Habib, S. J. Chun, B. G. Neel, and T. Vartanian (2003)
Mol. Cancer Res. 1, 219-233
 |  Abstract »  |  Full Text »

Effect of breast milk and weaning on epithelial growth of the small intestine in humans.

A G Cummins and F M Thompson (2002)
Gut 51, 748-754
 |  Abstract »  |  Full Text »  |  PDF »

ErbB Signaling Regulates Lineage Determination of Developing Pancreatic Islet Cells in Embryonic Organ Culture.

M.-A. Huotari, P. J. Miettinen, J. Palgi, T. Koivisto, J. Ustinov, D. Harari, Y. Yarden, and T. Otonkoski (2002)
Endocrinology 143, 4437-4446
 |  Abstract »  |  Full Text »  |  PDF »

Gab1 and SHP-2 promote Ras/MAPK regulation of epidermal growth and differentiation.

T. Cai, K. Nishida, T. Hirano, and P. A. Khavari (2002)
J. Cell Biol. 159, 103-112
 |  Abstract »  |  Full Text »  |  PDF »

An Activator Protein-1 Complex Mediates Epidermal Growth Factor Regulation of Equine Glycoprotein {alpha} Subunit Expression in Trophoblast Cells.

T. M. Thway and M. W. Wolfe (2002)
Biol Reprod 67, 972-980
 |  Abstract »  |  Full Text »  |  PDF »

Emerging Roles of TACE as a Key Protease in ErbB Ligand Shedding.

P. J. Dempsey, K. Garton, and E. W. Raines (2002)
Mol. Interv. 2, 136-141
 |  Abstract »  |  Full Text »

Tumor Necrosis Factor-alpha Converting Enzyme (TACE) Regulates Epidermal Growth Factor Receptor Ligand Availability.

S. W. Sunnarborg, C. L. Hinkle, M. Stevenson, W. E. Russell, C. S. Raska, J. J. Peschon, B. J. Castner, M. J. Gerhart, R. J. Paxton, R. A. Black, et al. (2002)
J. Biol. Chem. 277, 12838-12845
 |  Abstract »  |  Full Text »  |  PDF »

Novel ENU-induced eye mutations in the mouse: models for human eye disease.

C. Thaung, K. West, B. J. Clark, L. McKie, J. E. Morgan, K. Arnold, P. M. Nolan, J. Peters, A. J. Hunter, S. D. M. Brown, et al. (2002)
Hum. Mol. Genet. 11, 755-767
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture.

A. E. DeWitt, J. Y. Dong, H. S. Wiley, and D. A. Lauffenburger (2002)
J. Cell Sci. 114, 2301-2313
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Pharmacodynamic Studies of the Epidermal Growth Factor Receptor Inhibitor ZD1839 in Skin From Cancer Patients: Histopathologic and Molecular Consequences of Receptor Inhibition.

J. Albanell, F. Rojo, S. Averbuch, A. Feyereislova, J. M. Mascaro, R. Herbst, P. LoRusso, D. Rischin, S. Sauleda, J. Gee, et al. (2002)
J. Clin. Oncol. 20, 110-124
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Transforming Growth Factor {alpha}: A Promoter of Motoneuron Survival of Potential Biological Relevance.

S. Boillee, J. Cadusseau, M. Coulpier, G. Grannec, and M.-P. Junier (2001)
J. Neurosci. 21, 7079-7088
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Activated Extracellular Signal-regulated Kinases: Association with Epidermal Growth Factor Receptor/Transforming Growth Factor {alpha} Expression in Head and Neck Squamous Carcinoma and Inhibition by Anti-Epidermal Growth Factor Receptor Treatments.

J. Albanell, J. Codony-Servat, F. Rojo, J. M. Del Campo, S. Sauleda, J. Anido, G. Raspall, J. Giralt, J. Rosello, R. I. Nicholson, et al. (2001)
Cancer Res. 61, 6500-6510
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The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle.

T. Ellis, L. Gambardella, M. Horcher, S. Tschanz, J. Capol, P. Bertram, W. Jochum, Y. Barrandon, and M. Busslinger (2001)
Genes & Dev. 15, 2307-2319
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Regulation of Epidermal Growth Factor Receptor Signaling by Endocytosis and Intracellular Trafficking.

P. Burke, K. Schooler, and H. S. Wiley (2001)
Mol. Biol. Cell 12, 1897-1910
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Transgenic Studies of Pain and Analgesia: Mutation or Background Genotype?.

W. R. Lariviere, E. J. Chesler, and J. S. Mogil (2001)
J. Pharmacol. Exp. Ther. 297, 467-473
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A Ser365{->}Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.

L. Chen, C. Li, W. Qiao, X. Xu, and C. Deng (2001)
Hum. Mol. Genet. 10, 457-465
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Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase.

D Nath, N. Williamson, R Jarvis, and G Murphy (2001)
J. Cell Sci. 114, 1213-1220
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Surfactant protein A and lipid are internalized via the coated-pit pathway by type II pneumocytes.

P. A. Stevens, H. Wissel, S. Zastrow, D. Sieger, and K.-P. Zimmer (2001)
Am J Physiol Lung Cell Mol Physiol 280, L141-L151
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Transgenic study of energy homeostasis equation: implications and confounding influences.

A. INUI (2000)
FASEB J 14, 2158-2170
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Selective Alterations in Organ Sizes in Mice with a Targeted Disruption of the Insulin-Like Growth Factor Binding Protein-2 Gene.

T. L. Wood, L. E. Rogler, M. E. Czick, A. G.P. Schuller, and J. E. Pintar (2000)
Mol. Endocrinol. 14, 1472-1482
 |  Abstract »  |  Full Text »

The Epidermal Growth Factor Receptor Is Required to Maintain the Proliferative Population in the Basal Compartment of Epidermal Tumors.

L. A. Hansen, R. L. Woodson II, S. Holbus, K. Strain, Y.-C. Lo, and S. H. Yuspa (2000)
Cancer Res. 60, 3328-3332
 |  Abstract »  |  Full Text »

Basic Fibroblast Growth Factor (Fgf2) Is Necessary for Cell Proliferation and Neurogenesis in the Developing Cerebral Cortex.

R. Raballo, J. Rhee, R. Lyn-Cook, J. F. Leckman, M. L. Schwartz, and F. M. Vaccarino (2000)
J. Neurosci. 20, 5012-5023
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Mild spherocytic hereditary elliptocytosis and altered levels of alpha - and gamma -adducins in beta -adducin-deficient mice.

A. F. Muro, M. L. Marro, S. Gajovic, F. Porro, L. Luzzatto, and F. E. Baralle (2000)
Blood 95, 3978-3985
 |  Abstract »  |  Full Text »  |  PDF »

Antisense Inhibition of Epidermal Growth Factor Receptor Decreases Expression of Human Surfactant Protein A.

J. M. Klein, T. A. McCarthy, J. M. Dagle, and J. M. Snyder (2000)
Am. J. Respir. Cell Mol. Biol. 22, 676-684
 |  Abstract »  |  Full Text »

Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells.

H. J. McKenna, K. L. Stocking, R. E. Miller, K. Brasel, T. De Smedt, E. Maraskovsky, C. R. Maliszewski, D. H. Lynch, J. Smith, B. Pulendran, et al. (2000)
Blood 95, 3489-3497
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Jumonji, a Nuclear Protein That Is Necessary for Normal Heart Development.

Y. Lee, A. J. Song, R. Baker, B. Micales, S. J. Conway, and G. E. Lyons (2000)
Circ. Res. 86, 932-938
 |  Abstract »  |  Full Text »  |  PDF »

Review Article: Use of Transgenic Animals for Carcinogenicity Testing: Considerations and Implications for Risk Assessment.

D. Gulezian, D. Jacobson-Kram, C. B. Mccullough, H. Olson, L. Recio, D. Robinson, R. Storer, R. Tennant, J. M. Ward, and D. A. Neumann (2000)
Toxicol Pathol 28, 482-499
 |  Abstract »  |  PDF »

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