Science 27 January 1995: Vol. 267. no. 5197, pp. 518 - 522 DOI: 10.1126/science.7824950

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Articles

Mutant Parathyroid Hormone-Related Protein, Devoid of the Nuclear Localization Signal, Markedly Inhibits Arterial Smooth Muscle Cell Cycle and Neointima Formation by Coordinate Up-Regulation of p15Ink4b and p27kip1.

N. Fiaschi-Taesch, B. Sicari, K. Ubriani, I. Cozar-Castellano, K. K. Takane, and A. F. Stewart (2009)
Endocrinology 150, 1429-1439
 |  Abstract »  |  Full Text »  |  PDF »

pRb-Dependent Cyclin D3 Protein Stabilization Is Required for Myogenic Differentiation.

F. De Santa, S. Albini, E. Mezzaroma, L. Baron, A. Felsani, and M. Caruso (2007)
Mol. Cell. Biol. 27, 7248-7265
 |  Abstract »  |  Full Text »  |  PDF »

PKC{delta} mediates anti-proliferative, pro-apoptic effects of testosterone on coronary smooth muscle.

D. K. Bowles, K. K. Maddali, V. C. Dhulipala, and D. H. Korzick (2007)
Am J Physiol Cell Physiol 293, C805-C813
 |  Abstract »  |  Full Text »  |  PDF »

Epothilone B Inhibits Neointimal Formation after Rat Carotid Injury through the Regulation of Cell Cycle-Related Proteins.

Y. Lim, T.-J. Kim, Y.-R. Jin, D.-W. Kim, J.-S. Kwon, J.-H. Son, J.-C. Jung, M. A. Avery, D. J. Son, J. T. Hong, et al. (2007)
J. Pharmacol. Exp. Ther. 321, 648-655
 |  Abstract »  |  Full Text »  |  PDF »

l-Caldesmon Regulates Proliferation and Migration of Vascular Smooth Muscle Cells and Inhibits Neointimal Formation After Angioplasty.

K. Yokouchi, Y. Numaguchi, R. Kubota, M. Ishii, H. Imai, R. Murakami, Y. Ogawa, T. Kondo, K. Okumura, D. E. Ingber, et al. (2006)
Arterioscler Thromb Vasc Biol 26, 2231-2237
 |  Abstract »  |  Full Text »  |  PDF »

The role of endothelin-1 in vascular remodeling in vivo.

M. Takahashi (2006)
Cardiovasc Res 71, 4-5
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Macrophage retinoblastoma deficiency leads to enhanced atherosclerosis development in ApoE-deficient mice.

L. S. M. Boesten, A. S. M. Zadelaar, A. van Nieuwkoop, L. Hu, J. Jonkers, B. van de Water, M. J. J. Gijbels, I. van der Made, M. P. J. de Winther, L. M. Havekes, et al. (2006)
FASEB J 20, 953-955
 |  Abstract »  |  Full Text »  |  PDF »

Does gene therapy become pharmacotherapy?.

R. Morishita, M. Aoki, and T. Ogihara (2005)
Exp Physiol 90, 307-313
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy for the Extension of Vein Graft Patency: A Review.

A. Chandiwal, V. Balasubramanian, Z. K. Baldwin, M. S. Conte, and L. B. Schwartz (2005)
Vascular and Endovascular Surgery 39, 1-14
 |  Abstract »  |  PDF »

Antiproliferative effects of calcitonin gene-related peptide in aortic and pulmonary artery smooth muscle cells.

N. N. Chattergoon, F. M. D'Souza, W. Deng, H. Chen, A. L. Hyman, P. J. Kadowitz, and J. R. Jeter Jr. (2005)
Am J Physiol Lung Cell Mol Physiol 288, L202-L211
 |  Abstract »  |  Full Text »  |  PDF »

Current status of catheter- and stent-based gene therapy.

F. Sharif, K. Daly, J. Crowley, and T. O'Brien (2004)
Cardiovasc Res 64, 208-216
 |  Abstract »  |  Full Text »  |  PDF »

Retinoblastoma Protein Purification and Transduction of Retina and Retinoblastoma Cells Using Improved Alphavirus Vectors.

D. P. DiCiommo, A. Duckett, I. Burcescu, R. Bremner, and B. L. Gallie (2004)
Invest. Ophthalmol. Vis. Sci. 45, 3320-3329
 |  Abstract »  |  Full Text »  |  PDF »

Differential cyclin E expression in human in-stent stenosis smooth muscle cells identifies targets for selective anti-restenosis therapy.

M. O'Sullivan, S. D Scott, N. McCarthy, N. Figg, L. M Shapiro, P. Kirkpatrick, and M. R Bennett (2003)
Cardiovasc Res 60, 673-683
 |  Abstract »  |  Full Text »  |  PDF »

Vascular ligation response is independent of p107: stressing the role of the related p130.

J. R. Sindermann, C. Kobbert, F. Bauer, A. Skaletz-Rorowski, H. Hohage, G. Plenz, G. Breithardt, and K. L. March (2003)
Am J Physiol Heart Circ Physiol 285, H915-H918
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Transcription Factors AP-1 and NF-{kappa}B in Murine Chagasic Myocarditis.

H. Huang, S. B. Petkova, A. W. Cohen, B. Bouzahzah, J. Chan, J.-n. Zhou, S. M. Factor, L. M. Weiss, M. Krishnamachary, S. Mukherjee, et al. (2003)
Infect. Immun. 71, 2859-2867
 |  Abstract »  |  Full Text »  |  PDF »

Resveratrol Increases Serine15-Phosphorylated but Transcriptionally Impaired p53 and Induces a Reversible DNA Replication Block in Serum-Activated Vascular Smooth Muscle Cells.

U. G. B. Haider, D. Sorescu, K. K. Griendling, A. M. Vollmar, and V. M. Dirsch (2003)
Mol. Pharmacol. 63, 925-932
 |  Abstract »  |  Full Text »  |  PDF »

The Cyclin-Dependent Kinase Pathway Moves Forward.

K. E. Bornfeldt (2003)
Circ. Res. 92, 345-347
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OxLDL stimulates cell proliferation through a general induction of cell cycle proteins.

M. E. Zettler, M. A. Prociuk, J. A. Austria, H. Massaeli, G. Zhong, and G. N. Pierce (2003)
Am J Physiol Heart Circ Physiol 284, H644-H653
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism of eNOS gene transfer inhibition of vascular smooth muscle cell proliferation.

F. M. D'Souza, R. L. Sparks, H. Chen, P. J. Kadowitz, and J. R. Jeter Jr. (2003)
Am J Physiol Cell Physiol 284, C191-C199
 |  Abstract »  |  Full Text »  |  PDF »

Smooth muscle-specific expression of SV40 large TAg induces SMC proliferation causing adaptive arterial remodeling.

J. R. Sindermann, P. Babij, J. C. Klink, C. Kobbert, G. Plenz, J. Ebbing, L. Fan, and K. L. March (2002)
Am J Physiol Heart Circ Physiol 283, H2714-H2724
 |  Abstract »  |  Full Text »  |  PDF »

Direct evidence for the importance of p130 in injury response and arterial remodeling following carotid artery ligation.

J. R. Sindermann, J. Smith, C. Kobbert, G. Plenz, A. Skaletz-Rorowski, J. L. Solomon, L. Fan, and K. L. March (2002)
Cardiovasc Res 54, 676-683
 |  Abstract »  |  Full Text »  |  PDF »

Adenoviral Activin A Expression Prevents Intimal Hyperplasia in Human and Murine Blood Vessels by Maintaining the Contractile Smooth Muscle Cell Phenotype.

M. A. Engelse, J. H.P. Lardenoye, J. M. Neele, J. M. Grimbergen, M. R. de Vries, M. L.M. Lamfers, H. Pannekoek, P. H.A. Quax, and C. J.M. de Vries (2002)
Circ. Res. 90, 1128-1134
 |  Abstract »  |  Full Text »  |  PDF »

N-myc Promotes Survival and Induces S-Phase Entry of Postmitotic Sympathetic Neurons.

K. Wartiovaara, F. Barnabe-Heider, F. D. Miller, and D. R. Kaplan (2002)
J. Neurosci. 22, 815-824
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy for Cardiovascular Disease: A Case for Cautious Optimism.

R. Khurana, J. F. Martin, and I. Zachary (2001)
Hypertension 38, 1210-1216
 |  Abstract »  |  Full Text »  |  PDF »

Mutated p21/WAF/CIP transgene overexpression reduces smooth muscle cell proliferation, macrophage deposition, oxidation-sensitive mechanisms, and restenosis in hypercholesterolemic apolipoprotein E knockout mice.

G. CONDORELLI, J. K. AYCOCK, G. FRATI, and C. NAPOLI (2001)
FASEB J 15, 2162-2170
 |  Abstract »  |  Full Text »  |  PDF »

L-Arginine Administration Reduces Neointima Formation After Stent Injury in Rats by a Nitric Oxide-Mediated Mechanism.

P. Vermeersch, Z. Nong, E. Stabile, O. Varenne, H. Gillijns, M. Pellens, N. Van Pelt, M. Hoylaerts, I. De Scheerder, D. Collen, et al. (2001)
Arterioscler Thromb Vasc Biol 21, 1604-1609
 |  Abstract »  |  Full Text »  |  PDF »

Bench to Bedside: The Development of Rapamycin and Its Application to Stent Restenosis.

S. O. Marx and A. R. Marks (2001)
Circulation 104, 852-855
 |  Full Text »  |  PDF »

Retinoids: New Insight Into Smooth Muscle Cell Growth Inhibition.

J. M. Miano and B. C. Berk (2001)
Arterioscler Thromb Vasc Biol 21, 724-726
 |  Full Text »  |  PDF »

Cyclin-Dependent Kinase-2 in the Birth and Death of Cardiac Muscle Cells.

M. D. Schneider and W. R. MacLellan (2001)
Circ. Res. 88, 367-369
 |  Full Text »  |  PDF »

Analysis of SM22{alpha}-Deficient Mice Reveals Unanticipated Insights into Smooth Muscle Cell Differentiation and Function.

J. C. L. Zhang, S. Kim, B. P. Helmke, W. W. Yu, K. L. Du, M. M. Lu, M. Strobeck, Q.-C. Yu, and M. S. Parmacek (2001)
Mol. Cell. Biol. 21, 1336-1344
 |  Abstract »  |  Full Text »

Gene and Stem Cell Therapies.

E. H. Kaji and J. M. Leiden (2001)
JAMA 285, 545-550
 |  Abstract »  |  Full Text »  |  PDF »

Growth Suppression of Human Coronary Vascular Smooth Muscle Cells by Gene Transfer of the Transcription Factor E2F-1.

H. S. Shelat, T.-J. Liu, D. L. Hickman-Bick, M. K. Barnhart, T. Vida, P. M. Dillard, J. T. Willerson, and P. Zoldhelyi (2001)
Circulation 103, 407-414
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy for Cardiovascular Disease.

S. L. Meyerson, C. L. Skelly, M. A. Curi, and L. B. Schwartz (2000)
Seminars in Cardiothoracic and Vascular Anesthesia 4, 289-300
 |  Abstract »  |  PDF »

Evidence That Helix-Loop-Helix Proteins Collaborate with Retinoblastoma Tumor Suppressor Protein to Regulate Cortical Neurogenesis.

J. G. Toma, H. El-Bizri, F. Barnabe-Heider, R. Aloyz, and F. D. Miller (2000)
J. Neurosci. 20, 7648-7656
 |  Abstract »  |  Full Text »  |  PDF »

Adenoviral Vectors and Gene Transfer to the Blood Vessel Wall.

T. O'Brien (2000)
Arterioscler Thromb Vasc Biol 20, 1414-1416
 |  Full Text »  |  PDF »

Antisense and gene therapy to prevent restenosis.

A. Ehsan and M. J Mann (2000)
Vascular Medicine 5, 103-114
 |  Abstract »  |  PDF »

Doxazosin Inhibits Retinoblastoma Protein Phosphorylation and G1->S Transition in Human Coronary Smooth Muscle Cells.

U. Kintscher, S. Wakino, S. Kim, S. M. Jackson, E. Fleck, W. A. Hsueh, and R. E. Law (2000)
Arterioscler Thromb Vasc Biol 20, 1216-1224
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy for Restenosis.

M. R. Kibbe, T. R. Billiar, and E. Tzeng (2000)
Circ. Res. 86, 829-833
 |  Full Text »  |  PDF »

Nitric Oxide Modulates Expression of Cell Cycle Regulatory Proteins : A Cytostatic Strategy for Inhibition of Human Vascular Smooth Muscle Cell Proliferation.

F. C. Tanner, P. Meier, H. Greutert, C. Champion, E. G. Nabel, and T. F. Luscher (2000)
Circulation 101, 1982-1989
 |  Abstract »  |  Full Text »  |  PDF »

Local adenovirus-mediated transfer of C-type natriuretic peptide suppresses vascular remodeling in porcine coronary arteries in vivo.

K. Morishige, H. Shimokawa, T. Yamawaki, K. Miyata, Y. Eto, T. Kandabashi, K. Yogo, T. Higo, K. Egashira, H. Ueno, et al. (2000)
J. Am. Coll. Cardiol. 35, 1040-1047
 |  Abstract »  |  Full Text »  |  PDF »

Insights into the molecular pathogenesis of atherosclerosis and therapeutic strategies using gene transfer.

M. O Hiltunen, M. P Turunen, M. Laitinen, and S. Yla-Herttuala (2000)
Vascular Medicine 5, 41-48
 |  Abstract »  |  PDF »

Cyclic AMP Inhibited Proliferation of Human Aortic Vascular Smooth Muscle Cells, Accompanied by Induction of p53 and p21.

S.-i. Hayashi, R. Morishita, H. Matsushita, H. Nakagami, Y. Taniyama, T. Nakamura, M. Aoki, K. Yamamoto, J. Higaki, and T. Ogihara (2000)
Hypertension 35, 237-243
 |  Abstract »  |  Full Text »  |  PDF »

Adenoviral RB2/p130 Gene Transfer Inhibits Smooth Muscle Cell Proliferation and Prevents Restenosis After Angioplasty.

P. P. Claudio, L. Fratta, F. Farina, C. M. Howard, G. Stassi, S.-i. Numata, C. Pacilio, A. Davis, M. Lavitrano, M. Volpe, et al. (1999)
Circ. Res. 85, 1032-1039
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Rat Vascular Smooth Muscle Cell Proliferation In Vitro and In Vivo by Recombinant Replication-Competent Herpes Simplex Virus • Editorial Comment.

S.-I. Miyatake, H. Yukawa, H. Toda, N. Matsuoka, R. Takahashi, N. Hashimoto, and C. D. Kontos (1999)
Stroke 30 , 2431-2439
 |  Abstract »  |  Full Text »  |  PDF »

A Mouse Model of Arterial Gene Transfer : Antigen-Specific Immunity Is a Minor Determinant of the Early Loss of Adenovirus-Mediated Transgene Expression.

G. Vassalli, R. Agah, R. Qiao, C. Aguilar, and D. A. Dichek (1999)
Circ. Res. 85 , e25-e32
 |  Abstract »  |  Full Text »  |  PDF »

NAB2: A Transcriptional Brake for Activated Gene Expression in the Vessel Wall?.

J. M. Miano and B. C. Berk (1999)
Am. J. Pathol. 155, 1009-1012
 |  Full Text »  |  PDF »

Adenovirus-Mediated Expression of a Ribozyme to c-myb mRNA Inhibits Smooth Muscle Cell Proliferation and Neointima Formation In Vivo.

D. G. Macejak, H. Lin, S. Webb, J. Chase, K. Jensen, T. C. Jarvis, J. M. Leiden, and L. Couture (1999)
J. Virol. 73, 7745-7751
 |  Abstract »  |  Full Text »

Flavopiridol Inhibits Smooth Muscle Cell Proliferation In Vitro and Neointimal Formation In Vivo After Carotid Injury in the Rat.

J. Ruef, A. S. Meshel, Z. Hu, C. Horaist, C. A. Ballinger, L. J. Thompson, V. D. Subbarao, J. A. Dumont, and C. Patterson (1999)
Circulation 100, 659-665
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of the p53 Tumor Suppressor Gene Results in Growth of Human Aortic Vascular Smooth Muscle Cells : Potential Role of p53 in Regulation of Vascular Smooth Muscle Cell Growth.

M. Aoki, R. Morishita, H. Matsushita, S.-i. Hayashi, H. Nakagami, K. Yamamoto, A. Moriguchi, Y. Kaneda, J. Higaki, and T. Ogihara (1999)
Hypertension 34, 192-200
 |  Abstract »  |  Full Text »  |  PDF »

Prostacyclin synthase gene transfer inhibits neointimal formation in rat balloon-injured arteries without bleeding complications.

M. Harada, Y. Toki, Y. Numaguchi, H. Osanai, T. Ito, K. Okumura, and T. Hayakawa (1999)
Cardiovasc Res 43, 481-491
 |  Abstract »  |  Full Text »  |  PDF »

Adenovirus-Mediated Local Expression of Human Tissue Factor Pathway Inhibitor Eliminates Shear Stress–Induced Recurrent Thrombosis in the Injured Carotid Artery of the Rabbit.

T. Nishida, H. Ueno, N. Atsuchi, R. Kawano, Y. Asada, Y. Nakahara, Y.-i. Kamikubo, A. Takeshita, and H. Yasui (1999)
Circ. Res. 84, 1446-1452
 |  Abstract »  |  Full Text »  |  PDF »

Retroviral Gene Therapy in ApoE-Deficient Mice : ApoE Expression in the Artery Wall Reduces Early Foam Cell Lesion Formation.

A. H. Hasty, M. F. Linton, S. J. Brandt, V. R. Babaev, L. A. Gleaves, and S. Fazio (1999)
Circulation 99, 2571-2576
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Intimal Thickening After Balloon Angioplasty in Porcine Coronary Arteries by Targeting Regulators of the Cell Cycle.

R. Gallo, A. Padurean, T. Jayaraman, S. Marx, M. Roque, S. Adelman, J. Chesebro, J. Fallon, V. Fuster, A. Marks, et al. (1999)
Circulation 99, 2164-2170
 |  Abstract »  |  Full Text »  |  PDF »

Reversal of GATA-6 Downregulation Promotes Smooth Muscle Differentiation and Inhibits Intimal Hyperplasia in Balloon-Injured Rat Carotid Artery.

T. Mano, Z. Luo, S. L. Malendowicz, T. Evans, and K. Walsh (1999)
Circ. Res. 84, 647-654
 |  Abstract »  |  Full Text »  |  PDF »

Cell cycle regulatory molecules (cyclins, cyclin-dependent kinases and cyclin-dependent kinase inhibitors) and the cardiovascular system; potential targets for therapy?.

J.-M. Li and G. Brooks (1999)
Eur. Heart J. 20, 406-420
 |  PDF »

Prostacyclin Synthase Gene Transfer Accelerates Reendothelialization and Inhibits Neointimal Formation in Rat Carotid Arteries After Balloon Injury.

Y. Numaguchi, K. Naruse, M. Harada, H. Osanai, S. Mokuno, K. Murase, H. Matsui, Y. Toki, T. Ito, K. Okumura, et al. (1999)
Arterioscler Thromb Vasc Biol 19, 727-733
 |  Abstract »  |  Full Text »  |  PDF »

Prevention of Neointimal Formation by a Serine Protease Inhibitor, FUT-175, After Carotid Balloon Injury in Rats • Editorial Comment.

M. Sawada, H. Yanamoto, I. Nagata, N. Hashimoto, I. Nakahara, Y. Akiyama, H. Kikuchi, and R. L. Macdonald (1999)
Stroke 30, 644-650
 |  Abstract »  |  Full Text »  |  PDF »

RNA Antisense Abrogation of MAT1 Induces G1 Phase Arrest and Triggers Apoptosis in Aortic Smooth Muscle Cells.

L. Wu, P. Chen, J.-J. Hwang, L. W. Barsky, K. I. Weinberg, A. Jong, and V. A. Starnes (1999)
J. Biol. Chem. 274, 5564-5572
 |  Abstract »  |  Full Text »  |  PDF »

Vascular Gene Transfer : From Bench to Bedside.

I. J. Kullo, R. D. Simari, and R. S. Schwartz (1999)
Arterioscler Thromb Vasc Biol 19, 196-207
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Intimal Hyperplasia, Arterial Remodeling, and Restenosis: An Overview.

J. Heckenkamp and G. M. Lamuraglia (1999)
Perspectives in Vascular Surgery and Endovascular Therapy 11, 71-94
 |  Abstract »  |  PDF »

Is Gene Therapy for Hypertension Possible?.

M. I. Phillips (1999)
Hypertension 33, 8-13
 |  Full Text »  |  PDF »

Recombinant, Replication-Defective Adenovirus Gene Transfer Vectors Induce Cell Cycle Dysregulation and Inappropriate Expression of Cyclin Proteins.

R. P. Wersto, E. R. Rosenthal, P. K. Seth, N. T. Eissa, and R. E. Donahue (1998)
J. Virol. 72, 9491-9502
 |  Abstract »  |  Full Text »  |  PDF »

GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo.

E. E. Morrisey, Z. Tang, K. Sigrist, M. M. Lu, F. Jiang, H. S. Ip, and M. S. Parmacek (1998)
Genes & Dev. 12, 3579-3590
 |  Abstract »  |  Full Text »

Frontiers in Interventional Cardiology.

E. J. Topol and P. W. Serruys (1998)
Circulation 98, 1802-1820
 |  Full Text »  |  PDF »

Gene transfer to vein graft wall by HVJ-liposome method: time course and localization of gene expression.

H.-z. Bai, Y. Sawa, W.-d. Zhang, T. Yamakawa, R. Morishita, Y. Kaneda, and H. Matsuda (1998)
Ann. Thorac. Surg. 66, 814-819
 |  Abstract »  |  Full Text »  |  PDF »

Local Adenovirus-Mediated Transfer of Human Endothelial Nitric Oxide Synthase Reduces Luminal Narrowing After Coronary Angioplasty in Pigs.

O. Varenne, S. Pislaru, H. Gillijns, N. Van Pelt, R. D. Gerard, P. Zoldhelyi, F. Van de Werf, D. Collen, and S. P. Janssens (1998)
Circulation 98, 919-926
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Cellular Genes in a Chromosomal Context by the Retinoblastoma Tumor Suppressor Protein.

A. M. Buchmann, S. Swaminathan, and B. Thimmapaya (1998)
Mol. Cell. Biol. 18, 4565-4576
 |  Abstract »  |  Full Text »

Cell Cycle Progression : New Therapeutic Target for Vascular Proliferative Disease.

R. C. Braun-Dullaeus, M. J. Mann, and V. J. Dzau (1998)
Circulation 98, 82-89
 |  Abstract »  |  Full Text »  |  PDF »

Gene Transfer Into Normal and Atherosclerotic Human Blood Vessels.

M. D. Rekhter, R. D. Simari, C. W. Work, G. J. Nabel, E. G. Nabel, and D. Gordon (1998)
Circ. Res. 82, 1243-1252
 |  Abstract »  |  Full Text »  |  PDF »

Acute Host-Mediated Endothelial Injury After Adenoviral Gene Transfer in Normal Rabbit Arteries : Impact on Transgene Expression and Endothelial Function.

K. M. Channon, H. Qian, S. A. Youngblood, E. Olmez, G. A. Shetty, V. Neplioueva, M. A. Blazing, and S. E. George (1998)
Circ. Res. 82, 1253-1262
 |  Abstract »  |  Full Text »  |  PDF »

Isolation and Characterization of the 5'-Flanking Regulatory Region of the Human Natriuretic Peptide Receptor C Gene.

N. Yanaka, J. Kotera, and K. Omori (1998)
Endocrinology 139, 1389-1400
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy for Restenosis : Getting Nearer the Heart of the Matter.

S. Baek and K. L. March (1998)
Circ. Res. 82, 295-305
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy for Restenosis : Are We Ready?.

M. B. DeYoung and D. A. Dichek (1998)
Circ. Res. 82, 306-313
 |  Abstract »  |  Full Text »  |  PDF »

Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response.

M. Sata, H. Perlman, D. A. Muruve, M. Silver, M. Ikebe, T. A. Libermann, P. Oettgen, and K. Walsh (1998)
PNAS 95, 1213-1217
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Growth of Human Vascular Smooth Muscle Cells by Overexpression of p21 Gene Through Induction of Apoptosis.

H. Matsushita, R. Morishita, I. Kida, M. Aoki, S.-i. Hayashi, N. Tomita, K. Yamamoto, A. Moriguchi, A. Noda, Y. Kaneda, et al. (1998)
Hypertension 31, 493-498
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of Growth Factor Action : Implications for the Treatment of Cardiovascular Diseases.

J. Waltenberger (1997)
Circulation 96, 4083-4094
 |  Abstract »  |  Full Text »

Inhibition of Platelet-Derived Growth Factor BB–Induced Expression of Glyceraldehyde- 3-Phosphate Dehydrogenase by Sodium Butyrate in Rat Vascular Smooth Muscle Cells.

K. Ranganna and F. M. Yatsu (1997)
Arterioscler Thromb Vasc Biol 17, 3420-3427
 |  Abstract »  |  Full Text »

Intimal Hyperplasia After Balloon Injury Is Attenuated by Blocking Selectins.

M. K. Barron, R. S. Lake, A. J. Buda, and A. N. Tenaglia (1997)
Circulation 96, 3587-3592
 |  Abstract »  |  Full Text »

Possible uses of gene therapy in reducing coronary restenosis.

S NIKOL (1997)
Heart 78, 426-428
 |  Full Text »  |  PDF »

Adenovirus-Mediated Expression of the Secreted Form of Basic Fibroblast Growth Factor (FGF-2) Induces Cellular Proliferation and Angiogenesis In Vivo.

H. Ueno, J.-J. Li, S. Masuda, Z. Qi, H. Yamamoto, and A. Takeshita (1997)
Arterioscler Thromb Vasc Biol 17, 2453-2460
 |  Abstract »  |  Full Text »

Local Expression of C-Type Natriuretic Peptide Markedly Suppresses Neointimal Formation in Rat Injured Arteries Through an Autocrine/Paracrine Loop.

H. Ueno, A. Haruno, N. Morisaki, M. Furuya, K. Kangawa, A. Takeshita, and Y. Saito (1997)
Circulation 96, 2272-2279
 |  Abstract »  |  Full Text »

Adenoviral Constructs Encoding Phosphorylation-Competent Full-length and Truncated Forms of the Human Retinoblastoma Protein Inhibit Myocyte Proliferation and Neointima Formation.

R. C. Smith, K. N. Wills, D. Antelman, H. Perlman, L. N. Truong, K. Krasinski, and K. Walsh (1997)
Circulation 96, 1899-1905
 |  Abstract »  |  Full Text »

Augmented Adenovirus-Mediated Gene Transfer to Atherosclerotic Vessels.

H. Ooboshi, C. D. Rios, Y. Chu, S. D. Christenson, F. M. Faraci, B. L. Davidson, and D. D. Heistad (1997)
Arterioscler Thromb Vasc Biol 17, 1786-1792
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Optimal techniques for arterial gene transfer.

L. J Feldman and G. Steg (1997)
Cardiovasc Res 35, 391-404
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Prevention of vein graft failure: potential applications for gene therapy.

A. H Baker, D. Mehta, S. J George, and G. D Angelini (1997)
Cardiovasc Res 35, 442-450
 |  Abstract »  |  Full Text »  |  PDF »

Adenovirus gene therapy for hypercholesterolemia, thrombosis and restenosis.

R. D Gerard and D. Collen (1997)
Cardiovasc Res 35, 451-458
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Efficient adenoviral gene transfer to early venous bypass grafts: comparison with native vessels.

K. M Channon, G. J Fulton, J. L Gray, B. H Annex, G. A Shetty, M. A Blazing, K. G Peters, P.-O. Hagen, and S. E George (1997)
Cardiovasc Res 35, 505-513
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Percutaneous delivery of the gax gene inhibits vessel stenosis in a rabbit model of balloon angioplasty.

L. Maillard, E. Van Belle, R. C Smith, A. Le Roux, P. Denefle, G. Steg, J. J Barry, D. Branellec, J. M Isner, and K. Walsh (1997)
Cardiovasc Res 35, 536-546
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Vascular Smooth Muscle Cell Proliferation and Neointimal Accumulation by Adenovirus-Mediated Gene Transfer of Cytosine Deaminase.

R. L. Harrell, M. A. S. Rajanayagam, A. M. Doanes, R. J. Guzman, E. A. Hirschowitz, R. G. Crystal, S. E. Epstein, and T. Finkel (1997)
Circulation 96, 621-627
 |  Abstract »  |  Full Text »

Downregulation of Cyclin G1 Expression by Retrovirus-Mediated Antisense Gene Transfer Inhibits Vascular Smooth Muscle Cell Proliferation and Neointima Formation.

N. L. Zhu, L. Wu, P. X. Liu, E. M. Gordon, W. F. Anderson, V. A. Starnes, and F. L. Hall (1997)
Circulation 96, 628-635
 |  Abstract »  |  Full Text »

p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene..

R C Smith, D Branellec, D H Gorski, K Guo, H Perlman, J F Dedieu, C Pastore, A Mahfoudi, P Denefle, J M Isner, et al. (1997)
Genes & Dev. 11, 1674-1689
 |  Abstract »  |  PDF »

Protein Kinase C delta  Inhibits the Proliferation of Vascular Smooth Muscle Cells by Suppressing G1 Cyclin Expression.

S. Fukumoto, Y. Nishizawa, M. Hosoi, H. Koyama, K. Yamakawa, S. Ohno, and H. Morii (1997)
J. Biol. Chem. 272, 13816-13822
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Adenovirus-Mediated Transfer of a Dominant-Negative H-ras Suppresses Neointimal Formation in Balloon-Injured Arteries In Vivo.

H. Ueno, H. Yamamoto, S.-i. Ito, J.-J. Li, and A. Takeshita (1997)
Arterioscler Thromb Vasc Biol 17, 898-904
 |  Abstract »  |  Full Text »

p53 Expression Induces Apoptosis in Hippocampal Pyramidal Neuron Cultures.

J. Jordan, M. F. Galindo, J. H. M. Prehn, R. R. Weichselbaum, M. Beckett, G. D. Ghadge, R. P. Roos, J. M. Leiden, and R. J. Miller (1997)
J. Neurosci. 17, 1397-1405
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The DispatchTM catheter as a delivery tool for arterial gene transfer.

O. Tahlil, M. Brami, L. J Feldman, D. Branellec, and Ph.G. Steg (1997)
Cardiovasc Res 33, 181-187
 |  Abstract »  |  Full Text »  |  PDF »

Accelerated Restitution of Endothelial Integrity and Endothelium-Dependent Function After phVEGF165 Gene Transfer.

T. Asahara, D. Chen, Y. Tsurumi, M. Kearney, S. Rossow, J. Passeri, J. F. Symes, and J. M. Isner (1996)
Circulation 94, 3291-3302
 |  Abstract »  |  Full Text »

Enhancer Stimulation Unmasks Latent Gene Transfer After Adenovirus-Mediated Gene Delivery Into Human Vascular Smooth Muscle Cells.

G. J. Clesham, H. Browne, S. Efstathiou, and P. L. Weissberg (1996)
Circ. Res. 79, 1188-1195
 |  Abstract »  |  Full Text »

In Vivo Gene Transfer and Gene Modulation in Hypertension Research.

V. J. Dzau and M. Horiuchi (1996)
Hypertension 28, 1132-1137
 |  Abstract »  |  Full Text »

Angiotensin II Activation of Cyclin D1-dependent Kinase Activity.

G. Watanabe, R. J. Lee, C. Albanese, W. E. Rainey, D. Batlle, and R. G. Pestell (1996)
J. Biol. Chem. 271, 22570-22577
 |  Abstract »  |  Full Text »  |  PDF »

Intimal Hyperplasia: Prospects for Its Control in the Human.

M. A. Golden (1996)
Vascular and Endovascular Surgery 30, 361-364
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