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Science 30 September 1994:
Vol. 265. no. 5181, pp. 2077 - 2082
DOI: 10.1126/science.8091229
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Articles

Science, Vol 265, Issue 5181, 2077-2082
Copyright © 1994 by American Association for the Advancement of Science

articles

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII

M Johnston, S Andrews, R Brinkman, J Cooper, H Ding, J Dover, Z Du, A Favello, L Fulton, S Gattung, and al. et

Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110.

The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII reveals that it contains 269 predicted or known genes (300 base pairs or larger). Fifty-nine of these genes (22 percent) were previously identified. Of the 210 novel genes, 65 are predicted to encode proteins that are similar to other proteins of known or predicted function. Sixteen genes appear to be relatively recently duplicated. On average, there is one gene approximately every 2 kilobases. Although the coding density and base composition across the chromosome are not uniform, no regular pattern of variation is apparent.


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