Science 19 August 1994: Vol. 265. no. 5175, pp. 1098 - 1101 DOI: 10.1126/science.8066449

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Articles

Zebrafish kidney stromal cell lines support multilineage hematopoiesis.

D. L. Stachura, J. R. Reyes, P. Bartunek, B. H. Paw, L. I. Zon, and D. Traver (2009)
Blood 114, 279-289
 |  Abstract »  |  Full Text »  |  PDF »

Derivation of functional mature neutrophils from human embryonic stem cells.

Y. Yokoyama, T. Suzuki, M. Sakata-Yanagimoto, K. Kumano, K. Higashi, T. Takato, M. Kurokawa, S. Ogawa, and S. Chiba (2009)
Blood 113, 6584-6592
 |  Abstract »  |  Full Text »  |  PDF »

Expression of AA4.1 marks lymphohematopoietic progenitors in early mouse development.

T. Yamane, N. Hosen, H. Yamazaki, and I. L. Weissman (2009)
PNAS 106, 8953-8958
 |  Abstract »  |  Full Text »  |  PDF »

Development of CD4+CD25+FoxP3+ regulatory T cells from cord blood hematopoietic progenitor cells.

J. F. Hutton, T. Gargett, T. J. Sadlon, S. Bresatz, C. Y. Brown, H. Zola, M. F. Shannon, R. J. D'Andrea, and S. C. Barry (2009)
J. Leukoc. Biol. 85, 445-451
 |  Abstract »  |  Full Text »  |  PDF »

Two distinct types of murine blast colony-forming cells are multipotential hematopoietic precursors.

D. Metcalf, K. T. Greig, C. A. de Graaf, S. J. Loughran, W. S. Alexander, M. Kauppi, C. D. Hyland, L. Di Rago, and S. Mifsud (2008)
PNAS 105, 18501-18506
 |  Abstract »  |  Full Text »  |  PDF »

AML1/RUNX1 Works as a Negative Regulator of c-Mpl in Hematopoietic Stem Cells.

Y. Satoh, I. Matsumura, H. Tanaka, S. Ezoe, K. Fukushima, M. Tokunaga, M. Yasumi, H. Shibayama, M. Mizuki, T. Era, et al. (2008)
J. Biol. Chem. 283, 30045-30056
 |  Abstract »  |  Full Text »  |  PDF »

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells.

H. Nishikii, K. Eto, N. Tamura, K. Hattori, B. Heissig, T. Kanaji, A. Sawaguchi, S. Goto, J. Ware, and H. Nakauchi (2008)
J. Exp. Med. 205, 1917-1927
 |  Abstract »  |  Full Text »  |  PDF »

Notch-dependent control of myelopoiesis is regulated by fucosylation.

L. Zhou, L. W. Li, Q. Yan, B. Petryniak, Y. Man, C. Su, J. Shim, S. Chervin, and J. B. Lowe (2008)
Blood 112, 308-319
 |  Abstract »  |  Full Text »  |  PDF »

In vitro induction of natural killer T cells from embryonic stem cells prepared using somatic cell nuclear transfer.

H. Wakao, R. Wakao, S. Sakata, K. Iwabuchi, A. Oda, and H. Fujita (2008)
FASEB J 22, 2223-2231
 |  Abstract »  |  Full Text »  |  PDF »

Bloodlines of haematopoietic stem cell research in Japan.

H. Ema and H. Nakauchi (2008)
Phil Trans R Soc B 363, 2089-2097
 |  Abstract »  |  Full Text »  |  PDF »

Neural stem cells: involvement in adult neurogenesis and CNS repair.

H. Okano and K. Sawamoto (2008)
Phil Trans R Soc B 363, 2111-2122
 |  Abstract »  |  Full Text »  |  PDF »

Cdx gene deficiency compromises embryonic hematopoiesis in the mouse.

Y. Wang, A. Yabuuchi, S. McKinney-Freeman, D. M. K. Ducharme, M. K. Ray, K. Chawengsaksophak, T. K. Archer, and G. Q. Daley (2008)
PNAS 105, 7756-7761
 |  Abstract »  |  Full Text »  |  PDF »

Hematopoiesis and immunity of HOXB4-transduced embryonic stem cell-derived hematopoietic progenitor cells.

K.-M. Chan, S. Bonde, H. Klump, and N. Zavazava (2008)
Blood 111, 2953-2961
 |  Abstract »  |  Full Text »  |  PDF »

AKT signaling promotes derivation of embryonic germ cells from primordial germ cells.

T. Kimura, M. Tomooka, N. Yamano, K. Murayama, S. Matoba, H. Umehara, Y. Kanai, and T. Nakano (2008)
Development 135, 869-879
 |  Abstract »  |  Full Text »  |  PDF »

Identification of an Insulin-regulated Lysophospholipase with Homology to Neuropathy Target Esterase.

P. C. Kienesberger, A. Lass, K. Preiss-Landl, H. Wolinski, S. D. Kohlwein, R. Zimmermann, and R. Zechner (2008)
J. Biol. Chem. 283, 5908-5917
 |  Abstract »  |  Full Text »  |  PDF »

Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice.

S. Chappaz, L. Flueck, A. G. Farr, A. G. Rolink, and D. Finke (2007)
Blood 110, 3862-3870
 |  Abstract »  |  Full Text »  |  PDF »

The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.

O. Tanabe, Y. Shen, Q. Liu, A. D. Campbell, T. Kuroha, M. Yamamoto, and J. D. Engel (2007)
Genes & Dev. 21, 2832-2844
 |  Abstract »  |  Full Text »  |  PDF »

Functional Human Antigen-Specific T Cells Produced In Vitro Using Retroviral T Cell Receptor Transfer into Hematopoietic Progenitors.

A. U. van Lent, M. Nagasawa, M. M. van Loenen, R. Schotte, T. N. M. Schumacher, M. H. M. Heemskerk, H. Spits, and N. Legrand (2007)
J. Immunol. 179, 4959-4968
 |  Abstract »  |  Full Text »  |  PDF »

Bone Marrow-Derived Hemopoietic Precursors Commit to the T Cell Lineage Only after Arrival in the Thymic Microenvironment.

K. Heinzel, C. Benz, V. C. Martins, I. D. Haidl, and C. C. Bleul (2007)
J. Immunol. 178, 858-868
 |  Abstract »  |  Full Text »  |  PDF »

AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis.

M. Nakagawa, M. Ichikawa, K. Kumano, S. Goyama, M. Kawazu, T. Asai, S. Ogawa, M. Kurokawa, and S. Chiba (2006)
Blood 108, 3329-3334
 |  Abstract »  |  Full Text »  |  PDF »

Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development.

H. Sakamoto, G. Dai, K. Tsujino, K. Hashimoto, X. Huang, T. Fujimoto, M. Mucenski, J. Frampton, and M. Ogawa (2006)
Blood 108, 896-903
 |  Abstract »  |  Full Text »  |  PDF »

Discordant developmental waves of angioblasts and hemangioblasts in the early gastrulating mouse embryo..

C. Furuta, H. Ema, S.-i. Takayanagi, T. Ogaeri, D. Okamura, Y. Matsui, and H. Nakauchi (2006)
Development 133, 2771-2779
 |  Abstract »  |  Full Text »  |  PDF »

Creation of Engineered Cardiac Tissue In Vitro From Mouse Embryonic Stem Cells.

X.-M. Guo, Y.-S. Zhao, H.-X. Chang, C.-Y. Wang, L.-L. E, X.-A. Zhang, C.-M. Duan, L.-Z. Dong, H. Jiang, J. Li, et al. (2006)
Circulation 113, 2229-2237
 |  Abstract »  |  Full Text »  |  PDF »

Notch Signaling Requires GATA-2 to Inhibit Myelopoiesis from Embryonic Stem Cells and Primary Hemopoietic Progenitors.

R. F. de Pooter, T. M. Schmitt, J. L. de la Pompa, Y. Fujiwara, S. H. Orkin, and J. C. Zuniga-Pflucker (2006)
J. Immunol. 176, 5267-5275
 |  Abstract »  |  Full Text »  |  PDF »

Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells.

M. W. Lensch and G. Q. Daley (2006)
Blood 107, 2605-2612
 |  Abstract »  |  Full Text »  |  PDF »

The Notch ligand delta-1 is a hematopoietic development cofactor for plasmacytoid dendritic cells.

A. Olivier, E. Lauret, P. Gonin, and A. Galy (2006)
Blood 107, 2694-2701
 |  Abstract »  |  Full Text »  |  PDF »

Multipotential differentiation ability of GATA-1-null erythroid-committed cells..

K. Kitajima, J. Zheng, H. Yen, D. Sugiyama, and T. Nakano (2006)
Genes & Dev. 20, 654-659
 |  Abstract »  |  Full Text »  |  PDF »

Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B.

W. Dontje, R. Schotte, T. Cupedo, M. Nagasawa, F. Scheeren, R. Gimeno, H. Spits, and B. Blom (2006)
Blood 107, 2446-2452
 |  Abstract »  |  Full Text »  |  PDF »

Redirecting differentiation of hematopoietic progenitors by a transcription factor, GATA-2.

K. Kitajima, M. Tanaka, J. Zheng, H. Yen, A. Sato, D. Sugiyama, H. Umehara, E. Sakai, and T. Nakano (2006)
Blood 107, 1857-1863
 |  Abstract »  |  Full Text »  |  PDF »

Designer blood: creating hematopoietic lineages from embryonic stem cells.

A. L. Olsen, D. L. Stachura, and M. J. Weiss (2006)
Blood 107, 1265-1275
 |  Abstract »  |  Full Text »  |  PDF »

OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis.

N. E. Wolins, B. K. Quaynor, J. R. Skinner, A. Tzekov, C. Park, K. Choi, and P. E. Bickel (2006)
J. Lipid Res. 47, 450-460
 |  Abstract »  |  Full Text »  |  PDF »

Differential effects of GATA-1 on proliferation and differentiation of erythroid lineage cells.

J. Zheng, K. Kitajima, E. Sakai, T. Kimura, N. Minegishi, M. Yamamoto, and T. Nakano (2006)
Blood 107, 520-527
 |  Abstract »  |  Full Text »  |  PDF »

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells.

D. K. Fogg, C. Sibon, C. Miled, S. Jung, P. Aucouturier, D. R. Littman, A. Cumano, and F. Geissmann (2006)
Science 311, 83-87
 |  Abstract »  |  Full Text »  |  PDF »

Subversion of Protein Kinase C{alpha} Signaling in Hematopoietic Progenitor Cells Results in the Generation of a B-Cell Chronic Lymphocytic Leukemia-Like Population In vivo.

R. Nakagawa, J. W. Soh, and A. M. Michie (2006)
Cancer Res. 66, 527-534
 |  Abstract »  |  Full Text »  |  PDF »

Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1.

D. L. Stachura, S. T. Chou, and M. J. Weiss (2006)
Blood 107, 87-97
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic stem cell-derived hematopoietic stem cells.

Y. Wang, F. Yates, O. Naveiras, P. Ernst, and G. Q. Daley (2005)
PNAS 102, 19081-19086
 |  Abstract »  |  Full Text »  |  PDF »

Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells.

L. Yao, T. Yokota, L. Xia, P. W. Kincade, and R. P. McEver (2005)
Blood 106, 4093-4101
 |  Abstract »  |  Full Text »  |  PDF »

A critical function for B-Raf at multiple stages of myelopoiesis.

T. Kamata, J. Kang, T.-H. Lee, L. Wojnowski, C. A. Pritchard, and A. D. Leavitt (2005)
Blood 106, 833-840
 |  Abstract »  |  Full Text »  |  PDF »

IL-6 blocks a discrete early step in lymphopoiesis.

K. Maeda, Y. Baba, Y. Nagai, K. Miyazaki, A. Malykhin, K. Nakamura, P. W. Kincade, N. Sakaguchi, and K. M. Coggeshall (2005)
Blood 106, 879-885
 |  Abstract »  |  Full Text »  |  PDF »

T/B lineage choice occurs prior to intrathymic Notch signaling.

B. C. Harman, W. E. Jenkinson, S. M. Parnell, S. W. Rossi, E. J. Jenkinson, and G. Anderson (2005)
Blood 106, 886-892
 |  Abstract »  |  Full Text »  |  PDF »

A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision.

C. Benz and C. C. Bleul (2005)
J. Exp. Med. 202, 21-31
 |  Abstract »  |  Full Text »  |  PDF »

Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation.

T. Morisada, Y. Oike, Y. Yamada, T. Urano, M. Akao, Y. Kubota, H. Maekawa, Y. Kimura, M. Ohmura, T. Miyamoto, et al. (2005)
Blood 105, 4649-4656
 |  Abstract »  |  Full Text »  |  PDF »

High level of endothelial cell-specific gene expression by a combination of the 5' flanking region and the 5' half of the first intron of the VE-cadherin gene.

H. Hisatsune, K. Matsumura, M. Ogawa, A. Uemura, N. Kondo, J. K. Yamashita, H. Katsuta, S. Nishikawa, T. Chiba, and S.-I. Nishikawa (2005)
Blood 105, 4657-4663
 |  Abstract »  |  Full Text »  |  PDF »

Graded Levels of GATA-1 Expression Modulate Survival, Proliferation, and Differentiation of Erythroid Progenitors.

X. Pan, O. Ohneda, K. Ohneda, F. Lindeboom, F. Iwata, R. Shimizu, M. Nagano, N. Suwabe, S. Philipsen, K.-C. Lim, et al. (2005)
J. Biol. Chem. 280, 22385-22394
 |  Abstract »  |  Full Text »  |  PDF »

Tyrosine phosphatase SHP-1 acts at different stages of development to regulate hematopoiesis.

N. R. D. Paling and M. J. Welham (2005)
Blood 105, 4290-4297
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic stem cell differentiation: emergence of a new era in biology and medicine.

G. Keller (2005)
Genes & Dev. 19, 1129-1155
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic Stem Cells: Prospects for Developmental Biology and Cell Therapy.

A. M. Wobus and K. R. Boheler (2005)
Physiol Rev 85, 635-678
 |  Abstract »  |  Full Text »  |  PDF »

Identification of cardiac stem cells with FLK1, CD31, and VE-cadherin expression during embryonic stem cell differentiation.

M. Iida, T. Heike, M. Yoshimoto, S. Baba, H. Doi, and T. Nakahata (2005)
FASEB J 19, 371-378
 |  Abstract »  |  Full Text »  |  PDF »

Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal.

T. Yamane, S. J. Dylla, M. Muijtjens, and I. L. Weissman (2005)
PNAS 102, 3312-3317
 |  Abstract »  |  Full Text »  |  PDF »

The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential.

G. Balciunaite, R. Ceredig, and A. G. Rolink (2005)
Blood 105, 1930-1936
 |  Abstract »  |  Full Text »  |  PDF »

Notch Signals Inhibit the Development of Erythroid/Megakaryocytic Cells by Suppressing GATA-1 Activity through the Induction of HES1.

E. Ishiko, I. Matsumura, S. Ezoe, K. Gale, J. Ishiko, Y. Satoh, H. Tanaka, H. Shibayama, M. Mizuki, T. Era, et al. (2005)
J. Biol. Chem. 280, 4929-4939
 |  Abstract »  |  Full Text »  |  PDF »

Directing oncogenic fusion genes into stem cells via an SCL enhancer.

M. Eguchi, M. Eguchi-Ishimae, A. Green, T. Enver, and M. Greaves (2005)
PNAS 102, 1133-1138
 |  Abstract »  |  Full Text »  |  PDF »

Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential.

M. A. Vodyanik, J. A. Bork, J. A. Thomson, and I. I. Slukvin (2005)
Blood 105, 617-626
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of hematopoietic and endothelial cell differentiation from mouse embryonic stem cells by different culture conditions.

W. J. Zhang, C. Park, E. Arentson, and K. Choi (2005)
Blood 105, 111-114
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B Family Proteins Participate in Multiple Steps of Hematopoiesis through Elimination of Reactive Oxygen Species.

S. Nakata, I. Matsumura, H. Tanaka, S. Ezoe, Y. Satoh, J. Ishikawa, T. Era, and Y. Kanakura (2004)
J. Biol. Chem. 279, 55578-55586
 |  Abstract »  |  Full Text »  |  PDF »

Leukemogenesis Caused by Incapacitated GATA-1 Function.

R. Shimizu, T. Kuroha, O. Ohneda, X. Pan, K. Ohneda, S. Takahashi, S. Philipsen, and M. Yamamoto (2004)
Mol. Cell. Biol. 24, 10814-10825
 |  Abstract »  |  Full Text »  |  PDF »

The ETS Transcription Factor Spi-B Is Required for Human Plasmacytoid Dendritic Cell Development.

R. Schotte, M. Nagasawa, K. Weijer, H. Spits, and B. Blom (2004)
J. Exp. Med. 200, 1503-1509
 |  Abstract »  |  Full Text »  |  PDF »

Differentiation status dependent function of FOG-1.

M. Tanaka, J. Zheng, K. Kitajima, K. Kita, H. Yoshikawa, and T. Nakano (2004)
Genes Cells 9, 1213-1226
 |  Abstract »  |  Full Text »  |  PDF »

The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region.

S. Goyama, Y. Yamaguchi, Y. Imai, M. Kawazu, M. Nakagawa, T. Asai, K. Kumano, K. Mitani, S. Ogawa, S. Chiba, et al. (2004)
Blood 104, 3558-3564
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Notch1 Function by In Vitro T Cell Differentiation of Pax5 Mutant Lymphoid Progenitors.

S. Hoflinger, K. Kesavan, M. Fuxa, C. Hutter, B. Heavey, F. Radtke, and M. Busslinger (2004)
J. Immunol. 173, 3935-3944
 |  Abstract »  |  Full Text »  |  PDF »

Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells.

S. Carotta, S. Pilat, A. Mairhofer, U. Schmidt, H. Dolznig, P. Steinlein, and H. Beug (2004)
Blood 104, 1873-1880
 |  Abstract »  |  Full Text »  |  PDF »

Cross Talk between Retinoic Acid Signaling and Transcription Factor GATA-2.

S. Tsuzuki, K. Kitajima, T. Nakano, A. Glasow, A. Zelent, and T. Enver (2004)
Mol. Cell. Biol. 24, 6824-6836
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic Stem Cells As an Alternate Marrow Donor Source: Engraftment without Graft-Versus-Host Disease.

R. K. Burt, L. Verda, D.-A. Kim, Y. Oyama, K. Luo, and C. Link (2004)
J. Exp. Med. 199, 895-904
 |  Abstract »  |  Full Text »  |  PDF »

Development of definitive endoderm from embryonic stem cells in culture.

A. Kubo, K. Shinozaki, J. M. Shannon, V. Kouskoff, M. Kennedy, S. Woo, H. J. Fehling, and G. Keller (2004)
Development 131, 1651-1662
 |  Abstract »  |  Full Text »  |  PDF »

Production of functional platelets by differentiated embryonic stem (ES) cells in vitro.

T.-T. Fujimoto, S. Kohata, H. Suzuki, H. Miyazaki, and K. Fujimura (2003)
Blood 102, 4044-4051
 |  Abstract »  |  Full Text »  |  PDF »

In vitro generation of T lymphocytes from embryonic stem cell-derived prehematopoietic progenitors.

R. F. de Pooter, S. K. Cho, J. R. Carlyle, and J. C. Zuniga-Pflucker (2003)
Blood 102, 1649-1653
 |  Abstract »  |  Full Text »  |  PDF »

Maintenance of Mouse Male Germ Line Stem Cells In Vitro.

M. Nagano, B.-Y. Ryu, C. J. Brinster, M. R. Avarbock, and R. L. Brinster (2003)
Biol Reprod 68, 2207-2214
 |  Abstract »  |  Full Text »  |  PDF »

Cell context-specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors.

S. Wong, J. McLaughlin, D. Cheng, and O. N. Witte (2003)
Blood 101, 4088-4097
 |  Abstract »  |  Full Text »  |  PDF »

Generation and genetic modification of dendritic cells derived from mouse embryonic stem cells.

S. Senju, S. Hirata, H. Matsuyoshi, M. Masuda, Y. Uemura, K. Araki, K.-i. Yamamura, and Y. Nishimura (2003)
Blood 101, 3501-3508
 |  Abstract »  |  Full Text »  |  PDF »

Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis.

T. Schroeder, S. T. Fraser, M. Ogawa, S. Nishikawa, C. Oka, G. W. Bornkamm, S.-I. Nishikawa, T. Honjo, and U. Just (2003)
PNAS 100, 4018-4023
 |  Abstract »  |  Full Text »  |  PDF »

Neuropilin-1 on hematopoietic cells as a source of vascular development.

Y. Yamada, Y. Oike, H. Ogawa, Y. Ito, H. Fujisawa, T. Suda, and N. Takakura (2003)
Blood 101, 1801-1809
 |  Abstract »  |  Full Text »  |  PDF »

The role of nuclear factor-kappa B essential modulator (NEMO) in B cell development and survival.

S. Kim, R. N. A. La Motte-Mohs, D. Rudolph, J. C. Zuniga-Pflucker, and T. W. Mak (2003)
PNAS 100, 1203-1208
 |  Abstract »  |  Full Text »  |  PDF »

Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo.

H. K. A. Mikkola, Y. Fujiwara, T. M. Schlaeger, D. Traver, and S. H. Orkin (2003)
Blood 101, 508-516
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Characterization of Ehox, a Novel Homeobox Gene Essential for Embryonic Stem Cell Differentiation.

M. Jackson, J. W. Baird, N. Cambray, J. D. Ansell, L. M. Forrester, and G. J. Graham (2002)
J. Biol. Chem. 277, 38683-38692
 |  Abstract »  |  Full Text »  |  PDF »

The Common Myelolymphoid Progenitor: A Key Intermediate Stage in Hemopoiesis Generating T and B Cells.

M. Lu, H. Kawamoto, Y. Katsube, T. Ikawa, and Y. Katsura (2002)
J. Immunol. 169, 3519-3525
 |  Abstract »  |  Full Text »  |  PDF »

Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling.

K. Eto, R. Murphy, S. W. Kerrigan, A. Bertoni, H. Stuhlmann, T. Nakano, A. D. Leavitt, and S. J. Shattil (2002)
PNAS 99, 12819-12824
 |  Abstract »  |  Full Text »  |  PDF »

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro.

G. Lacaud, L. Gore, M. Kennedy, V. Kouskoff, P. Kingsley, C. Hogan, L. Carlsson, N. Speck, J. Palis, and G. Keller (2002)
Blood 100, 458-466
 |  Abstract »  |  Full Text »  |  PDF »

Orderly and Nonstochastic Acquisition of CD94/NKG2 Receptors by Developing NK Cells Derived from Embryonic Stem Cells In Vitro.

R. H. Lian, M. Maeda, S. Lohwasser, M. Delcommenne, T. Nakano, R. E. Vance, D. H. Raulet, and F. Takei (2002)
J. Immunol. 168, 4980-4987
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the earliest prethymic bipotent T/NK progenitor in murine fetal liver.

I. Douagi, F. Colucci, J. P. Di Santo, and A. Cumano (2002)
Blood 99, 463-471
 |  Abstract »  |  Full Text »  |  PDF »

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects.

X.-M. Dai, G. R. Ryan, A. J. Hapel, M. G. Dominguez, R. G. Russell, S. Kapp, V. Sylvestre, and E. R. Stanley (2002)
Blood 99, 111-120
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency of phospholipase C-{gamma}1 impairs renal development and hematopoiesis.

M. Shirane, H. Sawa, Y. Kobayashi, T. Nakano, K. Kitajima, Y. Shinkai, K. Nagashima, and I. Negishi (2001)
Development 128, 5173-5180
 |  Abstract »  |  Full Text »  |  PDF »

Expression and function of CD105 during the onset of hematopoiesis from Flk1+ precursors.

S. K. Cho, A. Bourdeau, M. Letarte, and J. C. Zuniga-Pflucker (2001)
Blood 98, 3635-3642
 |  Abstract »  |  Full Text »  |  PDF »

Stromal cells expressing ephrin-B2 promote the growth and sprouting of ephrin-B2+ endothelial cells.

X.-Q. Zhang, N. Takakura, Y. Oike, T. Inada, N. W. Gale, G. D. Yancopoulos, and T. Suda (2001)
Blood 98, 1028-1037
 |  Abstract »  |  Full Text »  |  PDF »

Fetal liver myelopoiesis occurs through distinct, prospectively isolatable progenitor subsets.

D. Traver, T. Miyamoto, J. Christensen, J. Iwasaki-Arai, K. Akashi, and I. L. Weissman (2001)
Blood 98, 627-635
 |  Abstract »  |  Full Text »  |  PDF »

Bone morphogenetic protein 4 induces efficient hematopoietic differentiation of rhesus monkey embryonic stem cells in vitro.

F. Li, S. Lu, L. Vida, J. A. Thomson, and G. R. Honig (2001)
Blood 98, 335-342
 |  Abstract »  |  Full Text »  |  PDF »

Exogenous clustered neuropilin 1 enhances vasculogenesis and angiogenesis.

Y. Yamada, N. Takakura, H. Yasue, H. Ogawa, H. Fujisawa, and T. Suda (2001)
Blood 97, 1671-1678
 |  Abstract »  |  Full Text »  |  PDF »

Immature Multipotent Hemopoietic Progenitors Lacking Long-Term Bone Marrow-Reconstituting Activity in the Aorta-Gonad-Mesonephros Region of Murine Day 10 Fetuses.

K. Ohmura, H. Kawamoto, M. Lu, T. Ikawa, S. Ozaki, K. Nakao, and Y. Katsura (2001)
J. Immunol. 166, 3290-3296
 |  Abstract »  |  Full Text »  |  PDF »

Signal Via Lymphotoxin-{{beta}}R on Bone Marrow Stromal Cells Is Required for an Early Checkpoint of NK Cell Development.

Q. Wu, Y. Sun, J. Wang, X. Lin, Y. Wang, L. E. Pegg, A. Futterer, K. Pfeffer, and Y.-X. Fu (2001)
J. Immunol. 166, 1684-1689
 |  Abstract »  |  Full Text »  |  PDF »

The Latent Transforming Growth Factor-beta -binding Protein-1 Promotes In Vitro Differentiation of Embryonic Stem Cells into Endothelium.

A. Gualandris, J. P. Annes, M. Arese, I. Noguera, V. Jurukovski, and D. B. Rifkin (2000)
Mol. Biol. Cell 11, 4295-4308
 |  Abstract »  |  Full Text »

VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis.

K. Hamada, Y. Oike, N. Takakura, Y. Ito, L. Jussila, D. J. Dumont, K. Alitalo, and T. Suda (2000)
Blood 96, 3793-3800
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.

M. Schuldiner, O. Yanuka, J. Itskovitz-Eldor, D. A. Melton, and N. Benvenisty (2000)
PNAS 97, 11307-11312
 |  Abstract »  |  Full Text »  |  PDF »

ESOP-1, a secreted protein expressed in the hematopoietic, nervous, and reproductive systems of embryonic and adult mice.

K. Kato, A. M. Morrison, T. Nakano, K. Tashiro, and T. Honjo (2000)
Blood 96, 362-364
 |  Abstract »  |  Full Text »  |  PDF »

Impairment of B lymphopoiesis in precocious aging (klotho) mice.

S. Okada, T. Yoshida, Z. Hong, G. Ishii, M. Hatano, M. Kuro-o, Y. Nabeshima, Y.-i. Nabeshima, and T. Tokuhisa (2000)
Int. Immunol. 12, 861-871
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of B Lymphocyte and Macrophage Development by Graded Expression of PU.1.

R. P. DeKoter and H. Singh (2000)
Science 288, 1439-1441
 |  Abstract »  |  Full Text »

Vascular endothelial growth factor synergistically enhances bone morphogenetic protein-4-dependent lymphohematopoietic cell generation from embryonic stem cells in vitro.

N. Nakayama, J. Lee, and L. Chiu (2000)
Blood 95, 2275-2283
 |  Abstract »  |  Full Text »  |  PDF »

Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate.

T. Era and O. N. Witte (2000)
PNAS 97, 1737-1742
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of hematopoietic lineage-specific gene expression by ES cell in vitro differentiation induction system.

T. Era, T. Takagi, T. Takahashi, J.-C. Bories, and T. Nakano (2000)
Blood 95, 870-878
 |  Abstract »  |  Full Text »  |  PDF »

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