Science 12 August 1994: Vol. 265. no. 5174, pp. 956 - 959 DOI: 10.1126/science.8052854

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Articles

Immunomodulation of Nasal Epithelial Cells by Staphylococcus aureus-Derived Serine Proteases.

C. Rudack, F. Sachse, N. Albert, K. Becker, and C. von Eiff (2009)
J. Immunol. 183, 7592-7601
 |  Abstract »  |  Full Text »  |  PDF »

The 6th Annual World Congress on the Insulin Resistance Syndrome.

Z. T. Bloomgarden (2009)
Diabetes Care 32, e127-e133
 |  Full Text »  |  PDF »

Edward F. Adolph Distinguished Lecture: Muscle as an endocrine organ: IL-6 and other myokines.

B. K. Pedersen (2009)
J Appl Physiol 107, 1006-1014
 |  Abstract »  |  Full Text »  |  PDF »

Soft Tissue Injections in the Athlete.

J. J. Nepple and M. J. Matava (2009)
Sports Health: A Multidisciplinary Approach 1, 396-404
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin Use and Survival After Diagnosis of Colorectal Cancer.

A. T. Chan, S. Ogino, and C. S. Fuchs (2009)
JAMA 302, 649-658
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Low-Dose Aspirin on Acute Inflammatory Responses in Humans.

T. Morris, M. Stables, A. Hobbs, P. de Souza, P. Colville-Nash, T. Warner, J. Newson, G. Bellingan, and D. W. Gilroy (2009)
J. Immunol. 183, 2089-2096
 |  Abstract »  |  Full Text »  |  PDF »

The Orphan Nuclear Receptor Nur77 Suppresses Endothelial Cell Activation Through Induction of I{kappa}B{alpha} Expression.

B. You, Y.-Y. Jiang, S. Chen, G. Yan, and J. Sun (2009)
Circ. Res. 104, 742-749
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor-{kappa}B Activation Contributes to Vascular Endothelial Dysfunction via Oxidative Stress in Overweight/Obese Middle-Aged and Older Humans.

G. L. Pierce, L. A. Lesniewski, B. R. Lawson, S. D. Beske, and D. R. Seals (2009)
Circulation 119, 1284-1292
 |  Abstract »  |  Full Text »  |  PDF »

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6.

B. K. Pedersen and M. A. Febbraio (2008)
Physiol Rev 88, 1379-1406
 |  Abstract »  |  Full Text »  |  PDF »

Induction of paraoxonase 1 and apolipoprotein A-I gene expression by aspirin.

P. Jaichander, K. Selvarajan, M. Garelnabi, and S. Parthasarathy (2008)
J. Lipid Res. 49, 2142-2148
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor-{kappa}B Is a Critical Mediator of Ste20-Like Proline-/Alanine-Rich Kinase Regulation in Intestinal Inflammation.

Y. Yan, G. Dalmasso, H. T. T. Nguyen, T. S. Obertone, L. Charrier-Hisamuddin, S. V. Sitaraman, and D. Merlin (2008)
Am. J. Pathol. 173, 1013-1028
 |  Abstract »  |  Full Text »  |  PDF »

Approaches to Treatment of Pre-Diabetes and Obesity and Promising New Approaches to Type 2 Diabetes.

Z. T. Bloomgarden (2008)
Diabetes Care 31, 1461-1466
 |  Full Text »  |  PDF »

Salicylates Increase Insulin Secretion in Healthy Obese Subjects.

J.-M. Fernandez-Real, A. Lopez-Bermejo, A.-B. Ropero, S. Piquer, A. Nadal, J. Bassols, R. Casamitjana, R. Gomis, E. Arnaiz, I. Perez, et al. (2008)
J. Clin. Endocrinol. Metab. 93, 2523-2530
 |  Abstract »  |  Full Text »  |  PDF »

Effects of isoproterenol treatment for 7 days on inflammatory mediators in the rat aorta.

A. P. C. Davel, L. E. Fukuda, L. L. De Sa, C. D. Munhoz, C. Scavone, D. Sanz-Rosa, V. Cachofeiro, V. Lahera, and L. V. Rossoni (2008)
Am J Physiol Heart Circ Physiol 295, H211-H219
 |  Abstract »  |  Full Text »  |  PDF »

The Apolipoprotein E-mimetic Peptide COG112 Inhibits the Inflammatory Response to Citrobacter rodentium in Colonic Epithelial Cells by Preventing NF-{kappa}B Activation.

K. Singh, R. Chaturvedi, M. Asim, D. P. Barry, N. D. Lewis, M. P. Vitek, and K. T. Wilson (2008)
J. Biol. Chem. 283, 16752-16761
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin and asthma: barking up the right tree?.

A. A Clayton, D. L Forrester, and A. J Knox (2008)
Thorax 63, 485-486
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17-Acetoxyjolkinolide B irreversibly inhibits I{kappa}B kinase and induces apoptosis of tumor cells.

S.-S. Yan, Y. Li, Y. Wang, S.-S. Shen, Y. Gu, H.-B. Wang, G.-W. Qin, and Q. Yu (2008)
Mol. Cancer Ther. 7, 1523-1532
 |  Abstract »  |  Full Text »  |  PDF »

Randomised aspirin assignment and risk of adult-onset asthma in the Women's Health Study.

T Kurth, R G Barr, J M Gaziano, and J E Buring (2008)
Thorax 63, 514-518
 |  Abstract »  |  Full Text »  |  PDF »

Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6.

F. S. Machado, L. Esper, A. Dias, R. Madan, Y. Gu, D. Hildeman, C. N. Serhan, C. L. Karp, and J. Aliberti (2008)
J. Exp. Med. 205, 1077-1086
 |  Abstract »  |  Full Text »  |  PDF »

Peroxisome Proliferator-Activated Receptor-{gamma} Agonist Rosiglitazone Reverses the Adverse Effects of Diet-Induced Obesity on Oocyte Quality.

C. E. Minge, B. D. Bennett, R. J. Norman, and R. L. Robker (2008)
Endocrinology 149, 2646-2656
 |  Abstract »  |  Full Text »  |  PDF »

Antiphospholipid antibodies induce vascular functional changes in mice: a mechanism of vascular lesions in antiphospholipid syndrome?.

C Belizna, A Lartigue, J Favre, D Gilbert, F Tron, H Levesque, C Thuillez, and V Richard (2008)
Lupus 17, 185-194
 |  Abstract »  |  PDF »

Salsalate Improves Glycemia and Inflammatory Parameters in Obese Young Adults.

A. Fleischman, S. E. Shoelson, R. Bernier, and A. B. Goldfine (2008)
Diabetes Care 31, 289-294
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin Enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Mediated Apoptosis in Hormone-Refractory Prostate Cancer Cells through Survivin Down-Regulation.

J. Yoo and Y. J. Lee (2007)
Mol. Pharmacol. 72, 1586-1592
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM.

M.G. Luciani, C. Campregher, and C. Gasche (2007)
Carcinogenesis 28, 2207-2217
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin, COX-2, and the Risk of Colorectal Cancer.

R. Benelli, N. Murashige, M. Kami, M. Ikeda, A. T. Chan, S. Ogino, and C. S. Fuchs (2007)
N. Engl. J. Med. 357, 824-825
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UR-1505, a New Salicylate, Blocks T Cell Activation through Nuclear Factor of Activated T Cells.

J. Roman, A. F. de Arriba, S. Barron, P. Michelena, M. Giral, M. Merlos, E. Bailon, M. Comalada, J. Galvez, A. Zarzuelo, et al. (2007)
Mol. Pharmacol. 72, 269-279
 |  Abstract »  |  Full Text »  |  PDF »

Elevated NF-{kappa}B responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosis.

C. Rae, S. Langa, S. J. Tucker, and D. J. MacEwan (2007)
PNAS 104, 12790-12795
 |  Abstract »  |  Full Text »  |  PDF »

The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.

Z. J. Roberts, N. Goutagny, P.-Y. Perera, H. Kato, H. Kumar, T. Kawai, S. Akira, R. Savan, D. van Echo, K. A. Fitzgerald, et al. (2007)
J. Exp. Med. 204, 1559-1569
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin and the Risk of Colorectal Cancer in Relation to the Expression of COX-2.

A. T. Chan, S. Ogino, and C. S. Fuchs (2007)
N. Engl. J. Med. 356, 2131-2142
 |  Abstract »  |  Full Text »  |  PDF »

Celecoxib Decreases Fatty Acid Synthase Expression via Down-Regulation of c-Jun N-Terminal Kinase-1.

S. Lu and M. C. Archer (2007)
Experimental Biology and Medicine 232, 643-653
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin activates the NF-{kappa}B signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer.

L. A. Stark, K. Reid, O. J. Sansom, F. V. Din, S. Guichard, I. Mayer, D. I. Jodrell, A. R. Clarke, and M. G. Dunlop (2007)
Carcinogenesis 28, 968-976
 |  Abstract »  |  Full Text »  |  PDF »

The Heterogeneity of Diabetes: Unraveling a Dispute: Is Systemic Inflammation Related to Islet Autoimmunity?.

M. Pietropaolo, E. Barinas-Mitchell, and L. H. Kuller (2007)
Diabetes 56, 1189-1197
 |  Abstract »  |  Full Text »  |  PDF »

Salicylates Trigger Protein Synthesis Inhibition in a Protein Kinase R-like Endoplasmic Reticulum Kinase-dependent Manner.

A. M. Silva, D. Wang, A. A. Komar, B. A. Castilho, and B. R. G. Williams (2007)
J. Biol. Chem. 282, 10164-10171
 |  Abstract »  |  Full Text »  |  PDF »

Salicylate-Based Anti-Inflammatory Drugs Inhibit the Early Lesion of Diabetic Retinopathy.

L. Zheng, S. J. Howell, D. A. Hatala, K. Huang, and T. S. Kern (2007)
Diabetes 56, 337-345
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Triflusal and Aspirin in a Rat Model of Cerebral Ischemia.

S. N. Whitehead, N. A. Bayona, G. Cheng, G. V. Allen, V. C. Hachinski, and D. F. Cechetto (2007)
Stroke 38, 381-387
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin and Decreased Adult-Onset Asthma: Randomized Comparisons from the Physicians' Health Study.

R. G. Barr, T. Kurth, M. J. Stampfer, J. E. Buring, C. H. Hennekens, and J. M. Gaziano (2007)
Am. J. Respir. Crit. Care Med. 175, 120-125
 |  Abstract »  |  Full Text »  |  PDF »

Emerging Mechanisms of Immunosuppression in Oral Cancers.

A. Jewett, C. Head, and N.A. Cacalano (2006)
Journal of Dental Research 85, 1061-1073
 |  Abstract »  |  Full Text »  |  PDF »

Essential Role of C-Rel in Nitric-Oxide Synthase-2 Transcriptional Activation: Time-Dependent Control by Salicylate.

K. A. Cieslik, W.-G. Deng, and K. K. Wu (2006)
Mol. Pharmacol. 70, 2004-2014
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory Response After Influenza Vaccination in Men With and Without Carotid Artery Disease.

C. L. Carty, P. Heagerty, K. Nakayama, E. C. McClung, J. Lewis, D. Lum, E. Boespflug, C. McCloud-Gehring, B. R. Soleimani, J. Ranchalis, et al. (2006)
Arterioscler Thromb Vasc Biol 26, 2738-2744
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin and Salicylate Suppress Polymorphonuclear Apoptosis Delay Mediated by Proinflammatory Stimuli.

S. Negrotto, E. Malaver, M. E. Alvarez, N. Pacienza, L. P. D'Atri, R. G. Pozner, R. M. Gomez, and M. Schattner (2006)
J. Pharmacol. Exp. Ther. 319, 972-979
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism.

G. M. Borthwick, A. S. Johnson, M. Partington, J. Burn, R. Wilson, and H. M. Arthur (2006)
FASEB J 20, 2009-2016
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin Induces Apoptosis through the Inhibition of Proteasome Function.

P. Dikshit, M. Chatterjee, A. Goswami, A. Mishra, and N. R. Jana (2006)
J. Biol. Chem. 281, 29228-29235
 |  Abstract »  |  Full Text »  |  PDF »

The Association between Aspirin Use and the Incidence of Colorectal Cancer in Women.

M. Allison, C. Garland, R. Chlebowski, M. Criqui, R. Langer, L. Wu, H. Roy, A. McTiernan, L. Kuller, and for the Women's Health Initiative Investigators (2006)
Am. J. Epidemiol. 164, 567-575
 |  Abstract »  |  Full Text »  |  PDF »

Halofuginone inhibits NF-{kappa}B and p38 MAPK in activated T cells.

M. Leiba, L. Cahalon, A. Shimoni, O. Lider, A. Zanin-Zhorov, I. Hecht, U. Sela, I. Vlodavsky, and A. Nagler (2006)
J. Leukoc. Biol. 80, 399-406
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin regulates expression and function of scavenger receptor-BI in macrophages: studies in primary human macrophages and in mice.

I. Tancevski, A. Wehinger, W. Schgoer, P. Eller, S. Cuzzocrea, B. Foeger, J. R. Patsch, and A. Ritsch (2006)
FASEB J 20, 1328-1335
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor-{kappa}B-Independent Anti-Inflammatory Action of Salicylate in Human Endothelial Cells: Induction of Heme Oxygenase-1 by the c-Jun N-Terminal Kinase/Activator Protein-1 Pathway.

R. Furst, S. B. Blumenthal, A. K. Kiemer, S. Zahler, and A. M. Vollmar (2006)
J. Pharmacol. Exp. Ther. 318, 389-394
 |  Abstract »  |  Full Text »  |  PDF »

Toward a Core Nutraceutical Program for Cancer Management.

M. F. McCarty and K. I. Block (2006)
Integr Cancer Ther 5, 150-171
 |  Abstract »  |  PDF »

Inhibition of Cardiac Hypertrophy by Triflusal (4-Trifluoromethyl Derivative of Salicylate) and Its Active Metabolite.

A. Planavila, R. Rodriguez-Calvo, A. F. de Arriba, R. M. Sanchez, J. C. Laguna, M. Merlos, and M. Vazquez-Carrera (2006)
Mol. Pharmacol. 69, 1174-1181
 |  Abstract »  |  Full Text »  |  PDF »

Lymphoid B cells induce NF-{kappa}B activation in high endothelial cells from human tonsils.

R. Naves, L. I. Reyes, M. Rosemblatt, S. Jacobelli, A. Gonzalez, and M. R. Bono (2006)
Int. Immunol. 18, 259-267
 |  Abstract »  |  Full Text »  |  PDF »

Sodium Salicylate Promotes Neutrophil Apoptosis by Stimulating Caspase-Dependent Turnover of Mcl-1.

M. Derouet, L. Thomas, D. A. Moulding, C. Akgul, A. Cross, R. J. Moots, and S. W. Edwards (2006)
J. Immunol. 176, 957-965
 |  Abstract »  |  Full Text »  |  PDF »

The intracellular domain of CD44 promotes the fusion of macrophages.

W. Cui, J. Z. Ke, Q. Zhang, H.-Z. Ke, C. Chalouni, and A. Vignery (2006)
Blood 107, 796-805
 |  Abstract »  |  Full Text »  |  PDF »

Pretreatment of Acetylsalicylic Acid Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis by Down-regulating BCL-2 Gene Expression.

K. M. Kim, J. J. Song, J. Y. An, Y. T. Kwon, and Y. J. Lee (2005)
J. Biol. Chem. 280, 41047-41056
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitor-{kappa}B kinase-{beta} regulates LPS-induced TNF-{alpha} production in cardiac myocytes through modulation of NF-{kappa}B p65 subunit phosphorylation.

G. Hall, I. S. Singh, L. Hester, J. D. Hasday, and T. B. Rogers (2005)
Am J Physiol Heart Circ Physiol 289, H2103-H2111
 |  Abstract »  |  Full Text »  |  PDF »

Long-term Use of Aspirin and Nonsteroidal Anti-inflammatory Drugs and Risk of Colorectal Cancer.

A. T. Chan, E. L. Giovannucci, J. A. Meyerhardt, E. S. Schernhammer, G. C. Curhan, and C. S. Fuchs (2005)
JAMA 294, 914-923
 |  Abstract »  |  Full Text »  |  PDF »

Interaction Between a Rat Model of Cerebral Ischemia and {beta}-Amyloid Toxicity: II. Effects of Triflusal.

S. Whitehead, G. Cheng, V. Hachinski, and D. F. Cechetto (2005)
Stroke 36, 1782-1789
 |  Abstract »  |  Full Text »  |  PDF »

Nucleolar Sequestration of RelA (p65) Regulates NF-{kappa}B-Driven Transcription and Apoptosis.

L. A. Stark and M. G. Dunlop (2005)
Mol. Cell. Biol. 25, 5985-6004
 |  Abstract »  |  Full Text »  |  PDF »

Mesalazine Improves Replication Fidelity in Cultured Colorectal Cells.

C. Gasche, A. Goel, L. Natarajan, and C. R. Boland (2005)
Cancer Res. 65, 3993-3997
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of p90 Ribosomal S6 Kinase-mediated CCAAT/Enhancer-binding Protein {beta} Activation and Cyclooxygenase-2 Expression by Salicylate.

K. A. Cieslik, Y. Zhu, M. Shtivelband, and K. K. Wu (2005)
J. Biol. Chem. 280, 18411-18417
 |  Abstract »  |  Full Text »  |  PDF »

Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic grafts.

N. R. Barshes, S. Wyllie, and J. A. Goss (2005)
J. Leukoc. Biol. 77, 587-597
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Control of COX-2 via C/EBP{beta}.

K. K. Wu, J.-Y. Liou, and K. Cieslik (2005)
Arterioscler Thromb Vasc Biol 25, 679-685
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor-{kappa}B Decoy Oligodeoxynucleotides Prevent Acute Lung Injury in Mice with Cecal Ligation and Puncture-Induced Sepsis.

N. Matsuda, Y. Hattori, S. Jesmin, and S. Gando (2005)
Mol. Pharmacol. 67, 1018-1025
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Variants in the UGT1A6 Enzyme, Aspirin Use, and the Risk of Colorectal Adenoma.

A. T. Chan, G. J. Tranah, E. L. Giovannucci, D. J. Hunter, and C. S. Fuchs (2005)
J Natl Cancer Inst 97, 457-460
 |  Abstract »  |  Full Text »  |  PDF »

Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1.

M. Arita, F. Bianchini, J. Aliberti, A. Sher, N. Chiang, S. Hong, R. Yang, N. A. Petasis, and C. N. Serhan (2005)
J. Exp. Med. 201, 713-722
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the caspase-8/Bid and Bax pathways in aspirin-induced apoptosis in gastric cancer.

Q. Gu, J. D. Wang, H. H.X. Xia, M. C.M. Lin, H. He, B. Zou, S. P. Tu, Y. Yang, X. G. Liu, S. K. Lam, et al. (2005)
Carcinogenesis 26, 541-546
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Peptide Derived from Vaccinia Virus A52R Protein That Inhibits Cytokine Secretion in Response to TLR-Dependent Signaling and Reduces In Vivo Bacterial-Induced Inflammation.

S. L. McCoy, S. E. Kurtz, C. J. MacArthur, D. R. Trune, and S. H. Hefeneider (2005)
J. Immunol. 174, 3006-3014
 |  Abstract »  |  Full Text »  |  PDF »

A New Pharmacological Effect of Salicylates: Inhibition of NFAT-Dependent Transcription.

M. Aceves, A. Duenas, C. Gomez, E. San Vicente, M. S. Crespo, and C. Garcia-Rodriguez (2004)
J. Immunol. 173, 5721-5729
 |  Abstract »  |  Full Text »  |  PDF »

Dobutamine Inhibits Phorbol-Myristate-Acetate-Induced Activation of Nuclear Factor-{kappa}B in Human T Lymphocytes In Vitro.

T. Loop, T. Bross, M. Humar, A. Hoetzel, R. Schmidt, H. L. Pahl, K. K. Geiger, and B. H. J. Pannen (2004)
Anesth. Analg. 99, 1508-1515
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin inhibits ox-LDL-mediated LOX-1 expression and metalloproteinase-1 in human coronary endothelial cells.

J.L. Mehta, J. Chen, F. Yu, and D.Y. Li (2004)
Cardiovasc Res 64, 243-249
 |  Abstract »  |  Full Text »  |  PDF »

Osmotic Diuretics Induce Adenosine A1 Receptor Expression and Protect Renal Proximal Tubular Epithelial Cells against Cisplatin-mediated Apoptosis.

S. C. Pingle, S. Mishra, A. Marcuzzi, S. G. Bhat, Y. Sekino, L. P. Rybak, and V. Ramkumar (2004)
J. Biol. Chem. 279, 43157-43167
 |  Abstract »  |  Full Text »  |  PDF »

Pioglitazone and Sodium Salicylate Protect Human {beta}-Cells against Apoptosis and Impaired Function Induced by Glucose and Interleukin-1{beta}.

E. Zeender, K. Maedler, D. Bosco, T. Berney, M. Y. Donath, and P. A. Halban (2004)
J. Clin. Endocrinol. Metab. 89, 5059-5066
 |  Abstract »  |  Full Text »  |  PDF »

Interaction between NO and COX pathways in retinal cells exposed to elevated glucose and retina of diabetic rats.

Y. Du, V. P. Sarthy, and T. S. Kern (2004)
Am J Physiol Regulatory Integrative Comp Physiol 287, R735-R741
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide increases IL-8 gene transcription and mRNA stability to enhance IL-8 gene expression in lung epithelial cells.

L. Sparkman and V. Boggaram (2004)
Am J Physiol Lung Cell Mol Physiol 287, L764-L773
 |  Abstract »  |  Full Text »  |  PDF »

Switching leukemia cell phenotype between life and death.

S. J. Tucker, C. Rae, A. F. Littlejohn, A. Paul, and D. J. MacEwan (2004)
PNAS 101, 12940-12945
 |  Abstract »  |  Full Text »  |  PDF »

Nonsteroidal Anti-Inflammatory Drugs Potentiate 1-Methyl-4-phenylpyridinium (MPP+)-Induced Cell Death by Promoting the Intracellular Accumulation of MPP+ in PC12 Cells.

N. Morioka, K. Kumagai, K. Morita, S. Kitayama, and T. Dohi (2004)
J. Pharmacol. Exp. Ther. 310, 800-807
 |  Abstract »  |  Full Text »  |  PDF »

Cyclooxygenase (COX)-2 Inhibitor Celecoxib Abrogates TNF-Induced NF-{kappa}B Activation through Inhibition of Activation of I{kappa}B{alpha} Kinase and Akt in Human Non-Small Cell Lung Carcinoma: Correlation with Suppression of COX-2 Synthesis.

S. Shishodia, D. Koul, and B. B. Aggarwal (2004)
J. Immunol. 173, 2011-2022
 |  Abstract »  |  Full Text »  |  PDF »

15-epi-lipoxin A4-mediated Induction of Nitric Oxide Explains How Aspirin Inhibits Acute Inflammation.

M. J. Paul-Clark, T. van Cao, N. Moradi-Bidhendi, D. Cooper, and D. W. Gilroy (2004)
J. Exp. Med. 200, 69-78
 |  Abstract »  |  Full Text »  |  PDF »

DNA array analysis of the effects of aspirin on colon cancer cells: involvement of Rac1.

J. C. H. Hardwick, M. van Santen, G. R. van den Brink, S. J. H. van Deventer, and M. P. Peppelenbosch (2004)
Carcinogenesis 25, 1293-1298
 |  Abstract »  |  Full Text »  |  PDF »

Thrombosis and Neointima Formation in Vein Grafts Are Inhibited by Locally Applied Aspirin Through Endothelial Protection.

E. Torsney, U. Mayr, Y. Zou, W. D. Thompson, Y. Hu, and Q. Xu (2004)
Circ. Res. 94, 1466-1473
 |  Abstract »  |  Full Text »  |  PDF »

Anti-Inflammatory Effects of Moxifloxacin on Activated Human Monocytic Cells: Inhibition of NF-{kappa}B and Mitogen-Activated Protein Kinase Activation and of Synthesis of Proinflammatory Cytokines.

T. Weiss, I. Shalit, H. Blau, S. Werber, D. Halperin, A. Levitov, and I. Fabian (2004)
Antimicrob. Agents Chemother. 48, 1974-1982
 |  Abstract »  |  Full Text »  |  PDF »

Cooperation between Aspirin-Triggered Lipoxin and Nitric Oxide (NO) Mediates Antiadhesive Properties of 2-(Acetyloxy)benzoic Acid 3-(Nitrooxymethyl)phenyl Ester (NCX-4016) (NO-Aspirin) on Neutrophil-Endothelial Cell Adherence.

S. Fiorucci, E. Distrutti, A. Mencarelli, G. Rizzo, A. R. D. Lorenzo, M. Baldoni, P. del Soldato, A. Morelli, and J. L. Wallace (2004)
J. Pharmacol. Exp. Ther. 309, 1174-1182
 |  Abstract »  |  Full Text »  |  PDF »

Heparin-disaccharide affects T cells: inhibition of NF-{kappa}B activation, cell migration, and modulation of intracellular signaling.

I. Hecht, R. Hershkoviz, S. Shivtiel, T. Lapidot, I. R. Cohen, O. Lider, and L. Cahalon (2004)
J. Leukoc. Biol. 75, 1139-1146
 |  Abstract »  |  Full Text »  |  PDF »

Altered AP-1 (Activating Protein-1) Activity and c-jun Activation in T Cells Exposed to the Amide Class Herbicide 3,4-Dichloropropionanilide (DCPA).

K. M. Brundage, R. Schafer, and J. B. Barnett (2004)
Toxicol. Sci. 79, 98-105
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of cytokines and nitric oxide production, and protection against lethal endotoxemia and viral myocarditis by a new NF-{kappa}B inhibitor.

A. Matsumori, Y. Nunokawa, A. Yamaki, K. Yamamoto, M.-W. Hwang, T. Miyamoto, M. Hara, R. Nishio, K. Kitaura-Inenaga, and K. Ono (2004)
Eur J Heart Fail 6, 137-144
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin and the Risk of Hodgkin's Lymphoma in a Population-Based Case-Control Study.

E. T. Chang, T. Zheng, E. G. Weir, M. Borowitz, R. B. Mann, D. Spiegelman, and N. E. Mueller (2004)
J Natl Cancer Inst 96, 305-315
 |  Abstract »  |  Full Text »  |  PDF »

Specific Inhibition of I{kappa}B Kinase Reduces Hyperalgesia in Inflammatory and Neuropathic Pain Models in Rats.

I. Tegeder, E. Niederberger, R. Schmidt, S. Kunz, H. Guhring, O. Ritzeler, M. Michaelis, and G. Geisslinger (2004)
J. Neurosci. 24, 1637-1645
 |  Abstract »  |  Full Text »  |  PDF »

A Prospective Study of Aspirin Use and the Risk for Colorectal Adenoma.

A. T. Chan, E. L. Giovannucci, E. S. Schernhammer, G. A. Colditz, D. J. Hunter, W. C. Willett, and C. S. Fuchs (2004)
Ann Intern Med 140, 157-166
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin-Mediated COX-2 Transcript Stabilization via Sustained p38 Activation in Human Intestinal Myofibroblasts.

R. C. Mifflin, J. I. Saada, J. F. Di Mari, J. D. Valentich, P. A. Adegboyega, and D. W. Powell (2004)
Mol. Pharmacol. 65, 470-478
 |  Abstract »  |  Full Text »  |  PDF »

Cyclooxygenase-2-Derived E Prostaglandins Down-Regulate Matrix Metalloproteinase-1 Expression in Fibroblast-Like Synoviocytes via Inhibition of Extracellular Signal-Regulated Kinase Activation.

M. H. Pillinger, P. B. Rosenthal, S. N. Tolani, B. Apsel, V. Dinsell, J. Greenberg, E. S. L. Chan, P. F. Gomez, and S. B. Abramson (2003)
J. Immunol. 171, 6080-6089
 |  Abstract »  |  Full Text »  |  PDF »

Growth Inhibition of Human Colon Cancer Cells by Nitric Oxide (NO)-Donating Aspirin Is Associated with Cyclooxygenase-2 Induction and {beta}-Catenin/T-Cell Factor Signaling, Nuclear Factor-{kappa}B, and NO Synthase 2 Inhibition: Implications for Chemoprevention.

J. L. Williams, N. Nath, J. Chen, T. R. Hundley, J. Gao, L. Kopelovich, K. Kashfi, and B. Rigas (2003)
Cancer Res. 63, 7613-7618
 |  Abstract »  |  Full Text »  |  PDF »

Antibiotic cyclic AMP signaling by "primed" leukocytes confers anti-inflammatory cytoprotection.

K. Abeyama, K.-i. Kawahara, S. Iino, T. Hamada, S.-i. Arimura, K. Matsushita, T. Nakajima, and I. Maruyama (2003)
J. Leukoc. Biol. 74, 908-915
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the Angiogenic Factor Thymidine Phosphorylase in THP-1 Monocytes: Induction by Autocrine Tumor Necrosis Factor-{alpha} and Inhibition by Aspirin.

G. H. Zhu and E. L. Schwartz (2003)
Mol. Pharmacol. 64, 1251-1258
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Interferon {gamma} Signaling by the Short Chain Fatty Acid Butyrate.

L. Klampfer, J. Huang, T. Sasazuki, S. Shirasawa, and L. Augenlicht (2003)
Mol. Cancer Res. 1, 855-862
 |  Abstract »  |  Full Text »  |  PDF »

Nonsteroidal antiinflammatory drugs inhibiting prostanoid efflux: As easy as ABC?.

T. D. Warner and J. A. Mitchell (2003)
PNAS 100, 9108-9110
 |  Full Text »  |  PDF »

Aspirin Protects Endothelial Cells From Oxidant Damage Via the Nitric Oxide-cGMP Pathway.

N. Grosser and H. Schroder (2003)
Arterioscler Thromb Vasc Biol 23, 1345-1351
 |  Abstract »  |  Full Text »  |  PDF »

Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival.

H. Liu, Y. Ma, S. M. Cole, C. Zander, K.-H. Chen, J. Karras, and R. M. Pope (2003)
Blood 102, 344-352
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C-associated Kinase Can Activate NF{kappa}B in Both a Kinase-dependent and a Kinase-independent Manner.

S. T. Moran, K. Haider, Y. Ow, P. Milton, L. Chen, and S. Pillai (2003)
J. Biol. Chem. 278, 21526-21533
 |  Abstract »  |  Full Text »  |  PDF »

Hypertonicity Inhibits Lipopolysaccharide-Induced Nitric Oxide Synthase Expression in Smooth Muscle Cells by Inhibiting Nuclear Factor {kappa}B.

S. C. Pingle, J. F. Sanchez, D. M. Hallam, A. L. Williamson, S. B. Maggirwar, and V. Ramkumar (2003)
Mol. Pharmacol. 63, 1238-1247
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B Is Involved in Regulation of CD40 Ligand Expression on Mycobacterium bovis Bacillus Calmette-Guerin-Activated Human T Cells.

P. Mendez-Samperio, H. Ayala, and A. Vazquez (2003)
Clin. Vaccine Immunol. 10, 376-382
 |  Abstract »  |  Full Text »  |  PDF »

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