Science 10 June 1994: Vol. 264. no. 5165, pp. 1599 - 1601 DOI: 10.1126/science.8202713

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Articles

Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response.

S. Deindl, T. A. Kadlecek, X. Cao, J. Kuriyan, and A. Weiss (2009)
PNAS 106, 20699-20704
 |  Abstract »  |  Full Text »  |  PDF »

TCR Signal Transduction: Opening the Black Box.

A. Weiss (2009)
J. Immunol. 183, 4821-4827
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Inhibition of ZAP-70 Kinase Activity via an Analog-sensitive Allele Blocks T Cell Receptor and CD28 Superagonist Signaling.

S. E. Levin, C. Zhang, T. A. Kadlecek, K. M. Shokat, and A. Weiss (2008)
J. Biol. Chem. 283, 15419-15430
 |  Abstract »  |  Full Text »  |  PDF »

Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.

T. Ilani, C. Khanna, M. Zhou, T. D. Veenstra, and A. Bretscher (2007)
J. Cell Biol. 179, 733-746
 |  Abstract »  |  Full Text »  |  PDF »

ZAP-70 Expression in Normal Pro/Pre B Cells, Mature B Cells, and in B-Cell Acute Lymphoblastic Leukemia.

M. Crespo, N. Villamor, E. Gine, A. Muntanola, D. Colomer, T. Marafioti, M. Jones, M. Camos, E. Campo, E. Montserrat, et al. (2006)
Clin. Cancer Res. 12, 726-734
 |  Abstract »  |  Full Text »  |  PDF »

Biased exon/intron distribution of cryptic and de novo 3' splice sites.

J. Kralovicova, M. B. Christensen, and I. Vorechovsky (2005)
Nucleic Acids Res. 33, 4882-4898
 |  Abstract »  |  Full Text »  |  PDF »

Carboxyl-Terminal Src Kinase Homologous Kinase Negatively Regulates the Chemokine Receptor CXCR4 through YY1 and Impairs CXCR4/CXCL12 (SDF-1{alpha})-Mediated Breast Cancer Cell Migration.

B.-C. Lee, T.-H. Lee, R. Zagozdzon, S. Avraham, A. Usheva, and H. K. Avraham (2005)
Cancer Res. 65, 2840-2845
 |  Abstract »  |  Full Text »  |  PDF »

The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine: IMPLICATIONS FOR THE DESIGN OF SELECTIVE INHIBITORS.

L. Jin, S. Pluskey, E. C. Petrella, S. M. Cantin, J. C. Gorga, M. J. Rynkiewicz, P. Pandey, J. E. Strickler, R. E. Babine, D. T. Weaver, et al. (2004)
J. Biol. Chem. 279, 42818-42825
 |  Abstract »  |  Full Text »  |  PDF »

The tandem Src homology 2 domain of the Syk kinase: A molecular device that adapts to interphosphotyrosine distances.

S. Kumaran, R. A. Grucza, and G. Waksman (2003)
PNAS 100, 14828-14833
 |  Abstract »  |  Full Text »  |  PDF »

G-protein-coupled receptor signaling in Syk-deficient neutrophils and mast cells.

A. Mocsai, H. Zhang, Z. Jakus, J. Kitaura, T. Kawakami, and C. A. Lowell (2003)
Blood 101, 4155-4163
 |  Abstract »  |  Full Text »  |  PDF »

The N-terminal SH2 Domains of Syk and ZAP-70 Mediate Phosphotyrosine-independent Binding to Integrin beta Cytoplasmic Domains.

D. G. Woodside, A. Obergfell, A. Talapatra, D. A. Calderwood, S. J. Shattil, and M. H. Ginsberg (2002)
J. Biol. Chem. 277, 39401-39408
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of T Cell Receptor-induced Activation of the Ras-ERK Pathway by Diacylglycerol Kinase zeta.

X.-P. Zhong, E. A. Hainey, B. A. Olenchock, H. Zhao, M. K. Topham, and G. A. Koretzky (2002)
J. Biol. Chem. 277, 31089-31098
 |  Abstract »  |  Full Text »  |  PDF »

Reconstitution of lymphoid development and function in ZAP-70-deficient mice following gene transfer into bone marrow cells.

M. Otsu, M. Steinberg, C. Ferrand, P. Merida, C. Rebouissou, P. Tiberghien, N. Taylor, F. Candotti, and N. Noraz (2002)
Blood 100, 1248-1256
 |  Abstract »  |  Full Text »  |  PDF »

Signaling through ZAP-70 is required for CXCL12-mediated T-cell transendothelial migration.

M. Ticchioni, C. Charvet, N. Noraz, L. Lamy, M. Steinberg, A. Bernard, and M. Deckert (2002)
Blood 99, 3111-3118
 |  Abstract »  |  Full Text »  |  PDF »

Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin.

S. M. Stepkowski, R. A. Erwin-Cohen, F. Behbod, M.-E. Wang, X. Qu, N. Tejpal, Z. S. Nagy, B. D. Kahan, and R. A. Kirken (2002)
Blood 99, 680-689
 |  Abstract »  |  Full Text »  |  PDF »

Requirement for Tyrosine Residues 315 and 319 within {zeta} Chain-Associated Protein 70 for T Cell Development.

Q. Gong, X. Jin, A. M. Akk, N. Foger, M. White, G. Gong, J. B. Wardenburg, and A. C. Chan (2001)
J. Exp. Med. 194, 507-518
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of NK Cell-Mediated Cytotoxicity by the Adaptor Protein 3BP2.

D. Jevremovic, D. D. Billadeau, R. A. Schoon, C. J. Dick, and P. J. Leibson (2001)
J. Immunol. 166, 7219-7228
 |  Abstract »  |  Full Text »  |  PDF »

ZAP-70 and SLP-76 Regulate Protein Kinase C-{{theta}} and NF-{{kappa}}B Activation in Response to Engagement of CD3 and CD28.

T. M. Herndon, X. C. Shan, G. C. Tsokos, and R. L. Wange (2001)
J. Immunol. 166, 5654-5664
 |  Abstract »  |  Full Text »  |  PDF »

Human equivalent of the mouse Nude/SCID phenotype: long-term evaluation of immunologic reconstitution after bone marrow transplantation.

C. Pignata, L. Gaetaniello, A. M. Masci, J. Frank, A. Christiano, E. Matrecano, and L. Racioppi (2001)
Blood 97, 880-885
 |  Abstract »  |  Full Text »  |  PDF »

Distinct T Cell Developmental Consequences in Humans and Mice Expressing Identical Mutations in the DLAARN Motif of ZAP-70.

M. E. Elder, S. Skoda-Smith, T. A. Kadlecek, F. Wang, J. Wu, and A. Weiss (2001)
J. Immunol. 166, 656-661
 |  Abstract »  |  Full Text »  |  PDF »

Differential Requirement of ZAP-70 for CD2-Mediated Activation Pathways of Mature Human T Cells.

E. Meinl, D. Lengenfelder, N. Blank, R. Pirzer, L. Barata, and C. Hivroz (2000)
J. Immunol. 165, 3578-3583
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Functional Requirement for SAP in 2B4-Mediated Activation of Human Natural Killer Cells as Revealed by the X-Linked Lymphoproliferative Syndrome.

S. G. Tangye, J. H. Phillips, L. L. Lanier, and K. E. Nichols (2000)
J. Immunol. 165, 2932-2936
 |  Abstract »  |  Full Text »  |  PDF »

Defective p56Lck activity in T cells from an adult patient with idiopathic CD4+ lymphocytopenia.

P. Hubert, F. Bergeron, V. Ferreira, M. Seligmann, E. Oksenhendler, P. Debre, and B. Autran (2000)
Int. Immunol. 12, 449-457
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory and Signaling Properties of the Vav Family.

X. R. Bustelo (2000)
Mol. Cell. Biol. 20, 1461-1477
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Resting Lymphocyte Kinase (Rlk/Txk) Targets Lymphoid Adaptor SLP-76 in the Cooperative Activation of Interleukin-2 Transcription in T-cells.

H. Schneider, B. Guerette, C. Guntermann, and C. E. Rudd (2000)
J. Biol. Chem. 275, 3835-3840
 |  Abstract »  |  Full Text »  |  PDF »

KinMutBase, a database of human disease-causing protein kinase mutations.

K. A. E. Stenberg, P. T. Riikonen, and M. Vihinen (2000)
Nucleic Acids Res. 28, 369-371
 |  Abstract »  |  Full Text »  |  PDF »

Point Mutation of a Tyrosine in the Linker Region of Syk Results in a Gain of Function.

K. Sada, J. Zhang, and R. P. Siraganian (2000)
J. Immunol. 164, 338-344
 |  Abstract »  |  Full Text »  |  PDF »

p56lck, ZAP-70, SLP-76, and Calcium-regulated Effectors Are Involved in NF-kappa B Activation by Bisperoxovanadium Phosphotyrosyl Phosphatase Inhibitors in Human T Cells.

M. Ouellet, B. Barbeau, and M. J. Tremblay (1999)
J. Biol. Chem. 274, 35029-35036
 |  Abstract »  |  Full Text »  |  PDF »

Requirement for B Cell Linker Protein (BLNK) in B Cell Development.

R. Pappu, A. M. Cheng, B. Li, Q. Gong, C. Chiu, N. Griffin, M. White, B. P. Sleckman, and A. C. Chan (1999)
Science 286, 1949-1954
 |  Abstract »  |  Full Text »

CD45 Is Essential for Fc{epsilon}RI Signaling by ZAP70, But Not Syk, in Syk-Negative Mast Cells.

J. Zhang and R. P. Siraganian (1999)
J. Immunol. 163, 2508-2516
 |  Abstract »  |  Full Text »  |  PDF »

Pre-T Cell Receptor Signals Are Responsible for the Down-Regulation of Syk Protein Tyrosine Kinase Expression.

D. H. Chu, N. S. C. van Oers, M. Malissen, J. Harris, M. Elder, and A. Weiss (1999)
J. Immunol. 163, 2610-2620
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Activation Stimulates the Association of Enzymatically Active Tyrosine-phosphorylated ZAP-70 with the Crk Adapter Proteins.

S. Gelkop and N. Isakov (1999)
J. Biol. Chem. 274, 21519-21527
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Dissection of Sle Pathogenesis: Sle3 on Murine Chromosome 7 Impacts T Cell Activation, Differentiation, and Cell Death.

C. Mohan, Y. Yu, L. Morel, P. Yang, and E. K. Wakeland (1999)
J. Immunol. 162, 6492-6502
 |  Abstract »  |  Full Text »  |  PDF »

Tyrosine 319, a Newly Identified Phosphorylation Site of ZAP-70, Plays a Critical Role in T Cell Antigen Receptor Signaling.

V. Di Bartolo, D. Mege, V. Germain, M. Pelosi, E. Dufour, F. Michel, G. Magistrelli, A. Isacchi, and O. Acuto (1999)
J. Biol. Chem. 274, 6285-6294
 |  Abstract »  |  Full Text »  |  PDF »

The Lck SH3 Domain Is Required for Activation of the Mitogen-activated Protein Kinase Pathway but Not the Initiation of T-cell Antigen Receptor Signaling.

M. F. Denny, H. C. Kaufman, A. C. Chan, and D. B. Straus (1999)
J. Biol. Chem. 274, 5146-5152
 |  Abstract »  |  Full Text »  |  PDF »

Interdomain B in ZAP-70 Regulates but Is Not Required for ZAP-70 Signaling Function in Lymphocytes.

Q. Zhao, B. L. Williams, R. T. Abraham, and A. Weiss (1999)
Mol. Cell. Biol. 19, 948-956
 |  Abstract »  |  Full Text »  |  PDF »

Src-Related Protein Tyrosine Kinases in Hematopoiesis.

S. J. Corey and S. M. Anderson (1999)
Blood 93, 1-14
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ZAP-70 Association with T Cell Receptor {zeta} (TCR{zeta}): Fluorescence Imaging of Dynamic Changes upon Cellular Stimulation.

J. Sloan-Lancaster, J. Presley, J. Ellenberg, T. Yamazaki, J. Lippincott-Schwartz, and L. E. Samelson (1998)
J. Cell Biol. 143, 613-624
 |  Abstract »  |  Full Text »  |  PDF »

Differential Requirements for ZAP-70 in TCR Signaling and T Cell Development.

T. A. Kadlecek, N. S. C. van Oers, L. Lefrancois, S. Olson, D. Finlay, D. H. Chu, K. Connolly, N. Killeen, and A. Weiss (1998)
J. Immunol. 161, 4688-4694
 |  Abstract »  |  Full Text »  |  PDF »

An Improved Retroviral Gene Transfer Technique Demonstrates Inhibition of CD4-CD8- Thymocyte Development by Kinase-Inactive ZAP-70.

T. Sugawara, V. Di Bartolo, T. Miyazaki, H. Nakauchi, O. Acuto, and Y. Takahama (1998)
J. Immunol. 161, 2888-2894
 |  Abstract »  |  Full Text »  |  PDF »

Tyrosine 474 of ZAP-70 Is Required for Association with the Shc Adaptor and for T-cell Antigen Receptor-dependent Gene Activation.

S. Pacini, C. Ulivieri, M. M. Di Somma, A. Isacchi, L. Lanfrancone, P. G. Pelicci, J. L. Telford, and C. T. Baldari (1998)
J. Biol. Chem. 273, 20487-20493
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Receptor-initiated Calcium Release Is Uncoupled from Capacitative Calcium Entry in Itk-deficient T Cells.

K.-Q. Liu, S. C. Bunnell, C. B. Gurniak, and L. J. Berg (1998)
J. Exp. Med. 187, 1721-1727
 |  Abstract »  |  Full Text »  |  PDF »

Nocodazole Inhibits Signal Transduction by the T Cell Antigen Receptor.

R. D. J. Huby, A. Weiss, and S. C. Ley (1998)
J. Biol. Chem. 273, 12024-12031
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Evidence of a Role for Lck in T-Cell Receptor Function Independent or Downstream of ZAP-70/Syk Protein Tyrosine Kinases.

J. Wong, D. Straus, and A. C. Chan (1998)
Mol. Cell. Biol. 18, 2855-2866
 |  Abstract »  |  Full Text »  |  PDF »

Natural and Engineered Disorders of Lymphocyte Development.

A. Fischer and B. Malissen (1998)
Science 280, 237-243
 |  Abstract »  |  Full Text »

Genetic Evidence for Differential Coupling of Syk Family Kinases to the T-Cell Receptor: Reconstitution Studies in a ZAP-70-Deficient Jurkat T-Cell Line.

B. L. Williams, K. L. Schreiber, W. Zhang, R. L. Wange, L. E. Samelson, P. J. Leibson, and R. T. Abraham (1998)
Mol. Cell. Biol. 18, 1388-1399
 |  Abstract »  |  Full Text »  |  PDF »

A High-Capacity Scintillation Proximity Assay for the Discovery and Evaluation of ZAP-70 Tandem SH2 Domain Antagonists.

M. P. Sheets, U. P. Warrior, H. Yoon, K. W. Mollison, S. W. Djuric, and J. M. Trevillyan (1998)
J Biomol Screen 3, 139-144
 |  Abstract »  |  PDF »

Cytoskeletal Polarization of T Cells Is Regulated by an Immunoreceptor Tyrosine-based Activation Motif-dependent Mechanism.

B. Lowin-Kropf, V. S. Shapiro, and A. Weiss (1998)
J. Cell Biol. 140, 861-871
 |  Abstract »  |  Full Text »  |  PDF »

Functional Role for Syk Tyrosine Kinase in Natural Killer Cell-mediated Natural Cytotoxicity.

K. M. Brumbaugh, B. A. Binstadt, D. D. Billadeau, R. A. Schoon, C. J. Dick, R. M. Ten, and P. J. Leibson (1997)
J. Exp. Med. 186, 1965-1974
 |  Abstract »  |  Full Text »  |  PDF »

Primary Immunodeficiency Diseases.

J. M. Puck (1997)
JAMA 278, 1835-1841
 |  Abstract »  |  PDF »

Regulation of ZAP-70 Intracellular Localization: Visualization with the Green Fluorescent Protein.

J. Sloan-Lancaster, W. Zhang, J. Presley, B. L. Williams, R. T. Abraham, J. Lippincott-Schwartz, and L. E. Samelson (1997)
J. Exp. Med. 186, 1713-1724
 |  Abstract »  |  Full Text »  |  PDF »

The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling.

A. M. Cheng, I. Negishi, S. J. Anderson, A. C. Chan, J. Bolen, D. Y. Loh, and T. Pawson (1997)
PNAS 94, 9797-9801
 |  Abstract »  |  Full Text »  |  PDF »

Perturbation of the T Lymphocyte Lineage In Transgenic Mice Expressing a Constitutive Repressor of Nuclear Factor (NF)-{kappa}B.

M. R. Boothby, A. L. Mora, D. C. Scherer, J. A. Brockman, and D. W. Ballard (1997)
J. Exp. Med. 185, 1897-1907
 |  Abstract »  |  Full Text »  |  PDF »

Development and function of T cells in T cell antigen receptor/CD3 zeta  knockout mice reconstituted with Fcvarepsilon RI gamma.

C.-P. Liu, W.-J. Lin, M. Huang, J. W. Kappler, and P. Marrack (1997)
PNAS 94, 616-621
 |  Abstract »  |  Full Text »  |  PDF »

Peripheral Expression of Jak3 Is Required to Maintain T Lymphocyte Function.

D. C. Thomis and L. J. Berg (1997)
J. Exp. Med. 185, 197-206
 |  Abstract »  |  Full Text »  |  PDF »

Mutation of Tyrosines 492/493 in the Kinase Domain of ZAP-70 Affects Multiple T-cell Receptor Signaling Pathways.

D. Mege, V. Di Bartolo, V. Germain, L. Tuosto, F. Michel, and O. Acuto (1996)
J. Biol. Chem. 271, 32644-32652
 |  Abstract »  |  Full Text »  |  PDF »

Differential Intrinsic Enzymatic Activity of Syk and Zap-70 Protein-tyrosine Kinases.

S. Latour, L. M.L. Chow, and A. Veillette (1996)
J. Biol. Chem. 271, 22782-22790
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of SLP-76 by the ZAP-70 Protein-tyrosine Kinase Is Required for T-cell Receptor Function.

J. B. Wardenburg, C. Fu, J. K. Jackman, H. Flotow, S. E. Wilkinson, D. H. Williams, R. Johnson, G. Kong, A. C. Chan, and P. R. Findell (1996)
J. Biol. Chem. 271, 19641-19644
 |  Abstract »  |  Full Text »  |  PDF »

An Activated Epidermal Growth Factor Receptor/Lck Chimera Restores Early T Cell Receptor-mediated Calcium Response in a CD45-deficient T Cell Line.

P. Duplay, A. Alcover, C. Fargeas, R. P. Sekaly, and P. E. Branton (1996)
J. Biol. Chem. 271, 17896-17902
 |  Abstract »  |  Full Text »  |  PDF »

Purification and Characterization of Human ZAP-70 Protein-tyrosine Kinase from a Baculovirus Expression System.

N. Isakov, R. L. Wange, J. D. Watts, R. Aebersold, and L. E. Samelson (1996)
J. Biol. Chem. 271, 15753-15761
 |  Abstract »  |  Full Text »  |  PDF »

SH2 Domain Function Is Essential for the Role of the Lck Tyrosine Kinase in T Cell Receptor Signal Transduction.

D. B. Straus, A. C. Chan, B. Patai, and A. Weiss (1996)
J. Biol. Chem. 271, 9976-9981
 |  Abstract »  |  Full Text »  |  PDF »

p120[IMAGE] Is a Major Substrate of Tyrosine Phosphorylation upon B Cell Antigen Receptor Stimulation and Interacts in Vivo with Fyn and Syk Tyrosine Kinases, Grb2 and Shc Adaptors, and the p85 Subunit of Phosphatidylinositol 3-Kinase.

G. Panchamoorthy, T. Fukazawa, S. Miyake, S. Soltoff, K. Reedquist, B. Druker, S. Shoelson, L. Cantley, and H. Band (1996)
J. Biol. Chem. 271, 3187-3194
 |  Abstract »  |  Full Text »  |  PDF »

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor.

J. H. Hanke, J. P. Gardner, R. L. Dow, P. S. Changelian, W. H. Brissette, E. J. Weringer, B. A. Pollok, and P. A. Connelly (1996)
J. Biol. Chem. 271, 695-701
 |  Abstract »  |  Full Text »  |  PDF »

Syk Mutation in Jurkat E6-derived Clones Results in Lack of p72[IMAGE] Expression.

J. Fargnoli, A. L. Burkhardt, M. Laverty, S. A. Kut, N. S. C. van Oers, A. Weiss, and J. B. Bolen (1995)
J. Biol. Chem. 270, 26533-26537
 |  Abstract »  |  Full Text »  |  PDF »

An SH3-binding Site Conserved in Bruton's Tyrosine Kinase and Related Tyrosine Kinases Mediates Specific Protein Interactions in Vitro and in Vivo.

W. Yang, S. N. Malek, and S. Desiderio (1995)
J. Biol. Chem. 270, 20832-20840
 |  Abstract »  |  Full Text »  |  PDF »

The Primary Immunodeficiencies.

F. S. Rosen, M. D. Cooper, and R. J.P. Wedgwood (1995)
N. Engl. J. Med. 333, 431-440
 |  Full Text »  |  PDF »

Activating and Inhibitory Mutations in Adjacent Tyrosines in the Kinase Domain of ZAP-70.

R. L. Wange, R.ón Guitián, N. Isakov, J. D. Watts, R. Aebersold, and L. E. Samelson (1995)
J. Biol. Chem. 270, 18730-18733
 |  Abstract »  |  Full Text »  |  PDF »

A role for CD5 in TCR-mediated signal transduction and thymocyte selection.

A Tarakhovsky, S. Kanner, J Hombach, J. Ledbetter, W Muller, N Killeen, and K Rajewsky (1995)
Science 269, 535-537
 |  Abstract »  |  PDF »

Interaction between lck and syk Family Tyrosine Kinases in Fc[IMAGE] Receptor-initiated Activation of Natural Killer Cells.

A. T. Ting, C. J. Dick, R. A. Schoon, L. M. Karnitz, R. T. Abraham, and P. J. Leibson (1995)
J. Biol. Chem. 270, 16415-16421
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Zap-70 by Src Family Tyrosine Protein Kinases in an Antigen-specific T-cell Line.

R. Weil, J.-F.ço. Cloutier, M. Fournel, and A. Veillette (1995)
J. Biol. Chem. 270, 2791-2799
 |  Abstract »  |  Full Text »  |  PDF »

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists.

J Madrenas, R. Wange, J. Wang, N Isakov, L. Samelson, and R. Germain (1995)
Science 267, 515-518
 |  Abstract »  |  PDF »

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase.

M. Elder, D Lin, J Clever, A. Chan, T. Hope, A Weiss, and T. Parslow (1994)
Science 264, 1596-1599
 |  Abstract »  |  PDF »

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency.

A. Chan, T. Kadlecek, M. Elder, A. Filipovich, W. Kuo, M Iwashima, T. Parslow, and A Weiss (1994)
Science 264, 1599-1601
 |  Abstract »  |  PDF »

Structural Characterization of Protein Kinase A as a Function of Nucleotide Binding. HYDROGEN-DEUTERIUM EXCHANGE STUDIES USING MATRIX-ASSISTED LASER DESORPTION IONIZATION-TIME OF FLIGHT MASS SPECTROMETRY DETECTION.

M. D. Andersen, J. Shaffer, P. A. Jennings, and J. A. Adams (2001)
J. Biol. Chem. 276, 14204-14211
 |  Abstract »  |  Full Text »  |  PDF »

Specific Dephosphorylation of the Lck Tyrosine Protein Kinase at Tyr-394 by the SHP-1 Protein-tyrosine Phosphatase.

G. G. Chiang and B. M. Sefton (2001)
J. Biol. Chem. 276, 23173-23178
 |  Abstract »  |  Full Text »  |  PDF »

Herpesvirus saimiri Replaces ZAP-70 for CD3- and CD2-mediated T Cell Activation.

E. Meinl, T. Derfuss, R. Pirzer, N. Blank, D. Lengenfelder, A. Blancher, F. Le Deist, B. Fleckenstein, and C. Hivroz (2001)
J. Biol. Chem. 276, 36902-36908
 |  Abstract »  |  Full Text »  |  PDF »

Alternative Antigen Receptor (TCR) Signaling in T Cells Derived from ZAP-70-deficient Patients Expressing High Levels of Syk.

N. Noraz, K. Schwarz, M. Steinberg, V. Dardalhon, C. Rebouissou, R. Hipskind, W. Friedrich, H. Yssel, K. Bacon, and N. Taylor (2000)
J. Biol. Chem. 275, 15832-15838
 |  Abstract »  |  Full Text »  |  PDF »

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