Science 10 June 1994: Vol. 264. no. 5165, pp. 1593 - 1596 DOI: 10.1126/science.7911253

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Articles

Involvement of Tissue Transglutaminase in Endothelin 1-Induced Hypertrophy in Cultured Neonatal Rat Cardiomyocytes.

X. Li, X.-L. Wei, L.-L. Meng, M.-G. Chi, J.-Q. Yan, X.-Y. Ma, Y.-S. Jia, L. Liang, H.-T. Yan, and J.-Q. Zheng (2009)
Hypertension 54, 839-844
 |  Abstract »  |  Full Text »  |  PDF »

Heparan Sulfate Proteoglycans Are Receptors for the Cell-surface Trafficking and Biological Activity of Transglutaminase-2.

A. Scarpellini, R. Germack, H. Lortat-Jacob, T. Muramatsu, E. Billett, T. Johnson, and E. A. M. Verderio (2009)
J. Biol. Chem. 284, 18411-18423
 |  Abstract »  |  Full Text »  |  PDF »

Transglutaminases and Disease: Lessons From Genetically Engineered Mouse Models and Inherited Disorders.

S. E. Iismaa, B. M. Mearns, L. Lorand, and R. M. Graham (2009)
Physiol Rev 89, 991-1023
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Transglutaminase Promotes or Suppresses Tumors Depending on Cell Context.

A. CHHABRA, A. VERMA, and K. MEHTA (2009)
Anticancer Res 29, 1909-1919
 |  Abstract »  |  Full Text »  |  PDF »

Transglutaminase 2 protects against ischemic insult, interacts with HIF1{beta}, and attenuates HIF1 signaling.

A. J. Filiano, C. D. C. Bailey, J. Tucholski, S. Gundemir, and G. V. W. Johnson (2008)
FASEB J 22, 2662-2675
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipase C-{delta}1 modulates sustained contraction of rat mesenteric small arteries in response to noradrenaline, but not endothelin-1.

C. J. Clarke, S. Forman, J. Pritchett, V. Ohanian, and J. Ohanian (2008)
Am J Physiol Heart Circ Physiol 295, H826-H834
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic Significance of Elevated Tissue Transglutaminase Expression in Pancreatic Cancer.

A. Verma, S. Guha, P. Diagaradjane, A. B. Kunnumakkara, A. M. Sanguino, G. Lopez-Berestein, A. K. Sood, B. B. Aggarwal, S. Krishnan, J. G. Gelovani, et al. (2008)
Clin. Cancer Res. 14, 2476-2483
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Transglutaminase Regulates Focal Adhesion Kinase/AKT Activation by Modulating PTEN Expression in Pancreatic Cancer Cells.

A. Verma, S. Guha, H. Wang, J. Y. Fok, D. Koul, J. Abbruzzese, and K. Mehta (2008)
Clin. Cancer Res. 14, 1997-2005
 |  Abstract »  |  Full Text »  |  PDF »

Hyperosmolarity-Induced Cornification of Human Corneal Epithelial Cells Is Regulated by JNK MAPK.

Z. Chen, L. Tong, Z. Li, K.-C. Yoon, H. Qi, W. Farley, D.-Q. Li, and S. C. Pflugfelder (2008)
Invest. Ophthalmol. Vis. Sci. 49, 539-549
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Transglutaminase Expression and Activity in Normal and Glaucomatous Human Trabecular Meshwork Cells and Tissues.

T. Tovar-Vidales, R. Roque, A. F. Clark, and R. J. Wordinger (2008)
Invest. Ophthalmol. Vis. Sci. 49, 622-628
 |  Abstract »  |  Full Text »  |  PDF »

Increased potency of {alpha}1-adrenergic receptors to induce inositol phosphates production correlates with the up-regulation of {alpha}1d/Gh{alpha}/phospholipase C{delta}1 signaling pathway in term rat myometrium.

M Dupuis, E Houdeau, and S Mhaouty-Kodja (2008)
Reproduction 135, 55-62
 |  Abstract »  |  Full Text »  |  PDF »

Identification of two GTP-independent alternatively spliced forms of tissue transglutaminase in human leukocytes, vascular smooth muscle, and endothelial cells.

T.-S. Lai, Y. Liu, W. Li, and C. S. Greenberg (2007)
FASEB J 21, 4131-4143
 |  Abstract »  |  Full Text »  |  PDF »

Cell-surface transglutaminase undergoes internalization and lysosomal degradation: an essential role for LRP1.

E. A. Zemskov, I. Mikhailenko, D. K. Strickland, and A. M. Belkin (2007)
J. Cell Sci. 120, 3188-3199
 |  Abstract »  |  Full Text »  |  PDF »

Transglutaminase 2 Kinase Activity Facilitates Protein Kinase A-induced Phosphorylation of Retinoblastoma Protein.

S. Mishra, G. Melino, and L. J. Murphy (2007)
J. Biol. Chem. 282, 18108-18115
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism of allosteric regulation of transglutaminase 2 by GTP.

G. E. Begg, L. Carrington, P. H. Stokes, J. M. Matthews, M. A. Wouters, A. Husain, L. Lorand, S. E. Iismaa, and R. M. Graham (2006)
PNAS 103, 19683-19688
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Follicle-Stimulating Hormone-Induced G{alpha}h/Phospholipase C-{delta}1 Signaling Pathway Mediating Rat Sertoli Cell Ca2+-Influx.

Y.-F. Lin, M.-J. Tseng, H.-L. Hsu, Y.-W. Wu, Y.-H. Lee, and Y.-H. Tsai (2006)
Mol. Endocrinol. 20, 2514-2527
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Linking Transglutaminases with G Protein-Coupled Receptor Signaling.

S. E. Iismaa, G. E. Begg, and R. M. Graham (2006)
Sci. STKE 2006, pe34
 |  Abstract »  |  Full Text »  |  PDF »

Tissue-transglutaminase contributes to neutrophil granulocyte differentiation and functions.

Z. Balajthy, K. Csomos, G. Vamosi, A. Szanto, M. Lanotte, and L. Fesus (2006)
Blood 108, 2045-2054
 |  Abstract »  |  Full Text »  |  PDF »

GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis.

L. Xu, S. Begum, J. D. Hearn, and R. O. Hynes (2006)
PNAS 103, 9023-9028
 |  Abstract »  |  Full Text »  |  PDF »

Mutation of a Critical Arginine in the GTP-binding Site of Transglutaminase 2 Disinhibits Intracellular Cross-linking Activity.

G. E. Begg, S. R. Holman, P. H. Stokes, J. M. Matthews, R. M. Graham, and S. E. Iismaa (2006)
J. Biol. Chem. 281, 12603-12609
 |  Abstract »  |  Full Text »  |  PDF »

Syntrophins Regulate {alpha}1D-Adrenergic Receptors through a PDZ Domain-mediated Interaction.

Z. Chen, C. Hague, R. A. Hall, and K. P. Minneman (2006)
J. Biol. Chem. 281, 12414-12420
 |  Abstract »  |  Full Text »  |  PDF »

Cell Surface Transglutaminase Promotes RhoA Activation via Integrin Clustering and Suppression of the Src-p190RhoGAP Signaling Pathway.

A. Janiak, E. A. Zemskov, and A. M. Belkin (2006)
Mol. Biol. Cell 17, 1606-1619
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Histones by Tissue Transglutaminase.

S. Mishra, A. Saleh, P. S. Espino, J. R. Davie, and L. J. Murphy (2006)
J. Biol. Chem. 281, 5532-5538
 |  Abstract »  |  Full Text »  |  PDF »

Proteolysis of Cell-Surface Tissue Transglutaminase by Matrix Metalloproteinase-2 Contributes to the Adhesive Defect and Matrix Abnormalities in Thrombospondin-2-Null Fibroblasts and Mice.

A. Agah, T. R. Kyriakides, and P. Bornstein (2005)
Am. J. Pathol. 167, 81-88
 |  Abstract »  |  Full Text »  |  PDF »

External GTP-bound Transglutaminase 2 Is a Molecular Switch for Chondrocyte Hypertrophic Differentiation and Calcification.

K. A. Johnson and R. A. Terkeltaub (2005)
J. Biol. Chem. 280, 15004-15012
 |  Abstract »  |  Full Text »  |  PDF »

Differential expression of multiple transglutaminases in human colon: impaired keratinocyte transglutaminase expression in ulcerative colitis.

G D'Argenio, M Calvani, N Della Valle, V Cosenza, G D. Matteo, P Giorgio, S Margarucci, O Petillo, F P Jori, U Galderisi, et al. (2005)
Gut 54, 496-502
 |  Abstract »  |  Full Text »  |  PDF »

Distinct pH Modulation for Dual Function of G{alpha}h (Transglutaminase II).

K. Y. Chae, J.-H. Kim, W.-J. Park, Y.-G. Kim, H.-Y. Yun, N. S. Kwon, M.-J. Im, and K. J. Baek (2005)
J. Biochem. 137, 407-413
 |  Abstract »  |  Full Text »  |  PDF »

Development of Magnetic Resonance Imaging Contrast Material for In vivo Mapping of Tissue Transglutaminase Activity.

G. Mazooz, T. Mehlman, T.-S. Lai, C. S. Greenberg, M. W. Dewhirst, and M. Neeman (2005)
Cancer Res. 65, 1369-1375
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Linking Vasomotor Tone and Vascular Remodeling: A Novel Function for Tissue Transglutaminase?.

B. L. Langille and D. Dajnowiec (2005)
Circ. Res. 96, 9-11
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Tissue Transglutaminase Is a Multifunctional BH3-only Protein.

C. Rodolfo, E. Mormone, P. Matarrese, F. Ciccosanti, M. G. Farrace, E. Garofano, L. Piredda, G. M. Fimia, W. Malorni, and M. Piacentini (2004)
J. Biol. Chem. 279, 54783-54792
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Sea Urchin Transglutaminase, a Protein Regulated by Guanine/Adenine Nucleotides.

L. Zanetti, F. Ristoratore, A. Bertoni, and L. Cariello (2004)
J. Biol. Chem. 279, 49289-49297
 |  Abstract »  |  Full Text »  |  PDF »

Analyses of Expression and Localization of Two Mammalian-Type Transglutaminases in Physarum polycephalum, an Acellular Slime Mold.

F. Wada, A. Ogawa, Y. Hanai, A. Nakamura, M. Maki, and K. Hitomi (2004)
J. Biochem. 136, 665-672
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}1B-Adrenoceptor Signaling and Cell Motility: GTPase FUNCTION OF Gh/TRANSGLUTAMINASE 2 INHIBITS CELL MIGRATION THROUGH INTERACTION WITH CYTOPLASMIC TAIL OF INTEGRIN {alpha} SUBUNITS.

S. K. Kang, K. S. Yi, N. S. Kwon, K.-H. Park, U.-H. Kim, K. J. Baek, and M.-J. Im (2004)
J. Biol. Chem. 279, 36593-36600
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Transglutaminase Has Intrinsic Kinase Activity: IDENTIFICATION OF TRANSGLUTAMINASE 2 AS AN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-3 KINASE.

S. Mishra and L. J. Murphy (2004)
J. Biol. Chem. 279, 23863-23868
 |  Abstract »  |  Full Text »  |  PDF »

Functional Coupling of Rat Myometrial {alpha}1-Adrenergic Receptors to Gh{alpha}/Tissue Transglutaminase 2 during Pregnancy.

M. Dupuis, A. Levy, and S. Mhaouty-Kodja (2004)
J. Biol. Chem. 279, 19257-19263
 |  Abstract »  |  Full Text »  |  PDF »

Cell Type-specific Activation of Intracellular Transglutaminase 2 by Oxidative Stress or Ultraviolet Irradiation: IMPLICATIONS OF TRANSGLUTAMINASE 2 IN AGE-RELATED CATARACTOGENESIS.

D.-M. Shin, J.-H. Jeon, C.-W. Kim, S.-Y. Cho, J.-C. Kwon, H.-J. Lee, K.-H. Choi, S.-C. Park, and I.-G. Kim (2004)
J. Biol. Chem. 279, 15032-15039
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Localization and Activity State of Tissue Transglutaminase Differentially Impacts Cell Death.

T. Milakovic, J. Tucholski, E. McCoy, and G. V. W. Johnson (2004)
J. Biol. Chem. 279, 8715-8722
 |  Abstract »  |  Full Text »  |  PDF »

Lessons from the Genome Sequence of Neurospora crassa: Tracing the Path from Genomic Blueprint to Multicellular Organism.

K. A. Borkovich, L. A. Alex, O. Yarden, M. Freitag, G. E. Turner, N. D. Read, S. Seiler, D. Bell-Pedersen, J. Paietta, N. Plesofsky, et al. (2004)
Microbiol. Mol. Biol. Rev. 68, 1-108
 |  Abstract »  |  Full Text »  |  PDF »

Evolutionary specialization of a tryptophan indole group for transition-state stabilization by eukaryotic transglutaminases.

S. E. Iismaa, S. Holman, M. A. Wouters, L. Lorand, R. M. Graham, and A. Husain (2003)
PNAS 100, 12636-12641
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Tissue Transglutaminase as a Novel Molecule Involved In Human CD8+ T Cell Transendothelial Migration.

K. Mohan, D. Pinto, and T. B. Issekutz (2003)
J. Immunol. 171, 3179-3186
 |  Abstract »  |  Full Text »  |  PDF »

Opposing Roles of Ras/Raf Oncogenes and the MEK1/ERK Signaling Module in Regulation of Expression and Adhesive Function of Surface Transglutaminase.

S. S. Akimov and A. M. Belkin (2003)
J. Biol. Chem. 278, 35609-35619
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Novel Gene Expression Targets for the Ras Association Domain Family 1 (RASSF1A) Tumor Suppressor Gene in Non-Small Cell Lung Cancer and Neuroblastoma.

A. Agathanggelou, I. Bieche, J. Ahmed-Choudhury, B. Nicke, R. Dammann, S. Baksh, B. Gao, J. D. Minna, J. Downward, E. R. Maher, et al. (2003)
Cancer Res. 63, 5344-5351
 |  Abstract »  |  Full Text »  |  PDF »

Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme.

B. Ahvazi, K. M. Boeshans, W. Idler, U. Baxa, and P. M. Steinert (2003)
J. Biol. Chem. 278, 23834-23841
 |  Abstract »  |  Full Text »  |  PDF »

Dissecting Cardiac Hypertrophy and Signaling Pathways: Evidence for an Interaction Between Multifunctional G Proteins and Prostanoids.

S. E. Iismaa and R. M. Graham (2003)
Circ. Res. 92, 1059-1061
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COX-2-Dependent Cardiac Failure in Gh/tTG Transgenic Mice.

Z. Zhang, R. Vezza, T. Plappert, P. McNamara, J. A. Lawson, S. Austin, D. Pratico, M. S.-J. Sutton, and G. A. FitzGerald (2003)
Circ. Res. 92, 1153-1161
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the Ras-ERK Pathway Inhibits Retinoic Acid-induced Stimulation of Tissue Transglutaminase Expression in NIH3T3 Cells.

M. A. Antonyak, C. J. McNeill, J. J. Wakshlag, J. E. Boehm, and R. A. Cerione (2003)
J. Biol. Chem. 278, 15859-15866
 |  Abstract »  |  Full Text »  |  PDF »

Transglutaminase Type II Plays a Protective Role in Hepatic Injury.

R. Nardacci, O. Lo Iacono, F. Ciccosanti, L. Falasca, M. Addesso, A. Amendola, G. Antonucci, A. Craxi, G. M. Fimia, V. Iadevaia, et al. (2003)
Am. J. Pathol. 162, 1293-1303
 |  Abstract »  |  Full Text »  |  PDF »

Trifunctional Chemical Probes for the Consolidated Detection and Identification of Enzyme Activities from Complex Proteomes.

G. C. Adam, E. J. Sorensen, and B. F. Cravatt (2002)
Mol. Cell. Proteomics 1, 828-835
 |  Abstract »  |  Full Text »  |  PDF »

Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient.

F. BERNASSOLA, M. FEDERICI, M. CORAZZARI, A. TERRINONI, M. L. HRIBAL, V. DE LAURENZI, M. RANALLI, O. MASSA, G. SESTI, W.H. IRWIN MCLEAN, et al. (2002)
FASEB J 16, 1371-1378
 |  Abstract »  |  Full Text »  |  PDF »

Anti-tissue transglutaminase antibodies from coeliac patients inhibit transglutaminase activity both in vitro and in situ.

C Esposito, F Paparo, I Caputo, M Rossi, M Maglio, D Sblattero, T Not, R Porta, S Auricchio, R Marzari, et al. (2002)
Gut 51, 177-181
 |  Abstract »  |  Full Text »  |  PDF »

Phosphoinositide 3-Kinase Activity Is Required for Retinoic Acid-induced Expression and Activation of the Tissue Transglutaminase.

M. A. Antonyak, J. E. Boehm, and R. A. Cerione (2002)
J. Biol. Chem. 277, 14712-14716
 |  Abstract »  |  Full Text »  |  PDF »

Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin.

S. S. Akimov and A. M. Belkin (2001)
Blood 98, 1567-1576
 |  Abstract »  |  Full Text »  |  PDF »

Pharmacological Separation of the Expression of Tissue Transglutaminase and Apoptosis after Chemotherapeutic Treatment of HepG2 Cells.

I. P. Uray, P. J. A. Davies, and L. Fésüs (2001)
Mol. Pharmacol. 59, 1388-1394
 |  Abstract »  |  Full Text »

Sympathoadrenergic mechanisms in functional regulation and development of cardiac hypertrophy and failure: findings from genetically engineered mice.

X.-J. Du (2001)
Cardiovasc Res 50, 443-453
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A Simple Assay and Histochemical Localization of Transglutaminase Activity Using a Derivative of Green Fluorescent Protein as Substrate.

Y. Furutani, A. Kato, M. Notoya, M. A. Ghoneim, and S. Hirose (2001)
J. Histochem. Cytochem. 49, 247-258
 |  Abstract »  |  Full Text »

Gene Disruption of Tissue Transglutaminase.

V. De Laurenzi and G. Melino (2001)
Mol. Cell. Biol. 21, 148-155
 |  Abstract »  |  Full Text »

Structure, Function, and Control of Phosphoinositide-Specific Phospholipase C.

M. J. Rebecchi and S. N. Pentyala (2000)
Physiol Rev 80, 1291-1335
 |  Abstract »  |  Full Text »  |  PDF »

Cooperation of p27Kip1 and p18INK4c in Progestin-Mediated Cell Cycle Arrest in T-47D Breast Cancer Cells.

A. Swarbrick, C. S. L. Lee, R. L. Sutherland, and E. A. Musgrove (2000)
Mol. Cell. Biol. 20, 2581-2591
 |  Abstract »  |  Full Text »

Sporadic Inclusion Body Myositis Correlates with Increased Expression and Cross-linking by Transglutaminases 1 and 2.

Y.-C. Choi, G. T. Park, T.-S. Kim, I.-N. Sunwoo, P. M. Steinert, and S.-Y. Kim (2000)
J. Biol. Chem. 275, 8703-8710
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Transglutaminase Is an Integrin-Binding Adhesion Coreceptor for Fibronectin.

S. S. Akimov, D. Krylov, L. F. Fleischman, and A. M. Belkin (2000)
J. Cell Biol. 148, 825-838
 |  Abstract »  |  Full Text »  |  PDF »

Opposite Effects of Ca2+ and GTP Binding on Tissue Transglutaminase Tertiary Structure.

A. Di Venere, A. Rossi, F. De Matteis, N. Rosato, A. F. Agro, and G. Mei (2000)
J. Biol. Chem. 275, 3915-3921
 |  Abstract »  |  Full Text »  |  PDF »

Adrenergic and Muscarinic Receptors in the Human Heart.

O.-E. Brodde and M. C. Michel (1999)
Pharmacol. Rev. 51, 651-690
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of "Tissue" Transglutaminase Increases Cell Survival by Preventing Apoptosis.

S. Oliverio, A. Amendola, C. Rodolfo, A. Spinedi, and M. Piacentini (1999)
J. Biol. Chem. 274, 34123-34128
 |  Abstract »  |  Full Text »  |  PDF »

Transglutaminase Type 1 and Its Cross-linking Activity Are Concentrated at Adherens Junctions in Simple Epithelial Cells.

T. Hiiragi, H. Sasaki, A. Nagafuchi, H. Sabe, S. C. Shen, M. Matsuki, K. Yamanishi, and S. Tsukita (1999)
J. Biol. Chem. 274, 34148-34154
 |  Abstract »  |  Full Text »  |  PDF »

Transglutaminase Activity in the Eye: Cross-linking in Epithelia and Connective Tissue Structures.

M. Raghunath, R. Cankay, U. Kubitscheck, J. D. Fauteck, R. Mayne, D. Aeschlimann, and U. Schlotzer-Schrehardt (1999)
Invest. Ophthalmol. Vis. Sci. 40, 2780-2787
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression of Multiple Transglutaminases in Human Brain. INCREASED EXPRESSION AND CROSS-LINKING BY TRANSGLUTAMINASES 1 AND 2 IN ALZHEIMER'S DISEASE.

S.-Y. Kim, P. Grant, J.-H. Lee, H. C. Pant, and P. M. Steinert (1999)
J. Biol. Chem. 274, 30715-30721
 |  Abstract »  |  Full Text »  |  PDF »

Interactions of Gh/transglutaminase with phospholipase Cdelta 1 and with GTP.

S. N. P. Murthy, J. W. Lomasney, E. C. Mak, and L. Lorand (1999)
PNAS 96, 11815-11819
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipase C-delta 1 Is Activated by Capacitative Calcium Entry That Follows Phospholipase C-beta Activation upon Bradykinin Stimulation.

Y.-H. Kim, T.-J. Park, Y. H. Lee, K. J. Baek, P.-G. Suh, S. H. Ryu, and K.-T. Kim (1999)
J. Biol. Chem. 274, 26127-26134
 |  Abstract »  |  Full Text »  |  PDF »

Cardiac Specific Overexpression of Transglutaminase II (Gh) Results in a Unique Hypertrophy Phenotype Independent of Phospholipase C Activation.

K. Small, J.-F. Feng, J. Lorenz, E. T. Donnelly, A. Yu, M.-J. Im, G. W. Dorn II, and S. B. Liggett (1999)
J. Biol. Chem. 274, 21291-21296
 |  Abstract »  |  Full Text »  |  PDF »

Differential Signaling by the Thromboxane Receptor Isoforms via the Novel GTP-binding Protein, Gh.

R. Vezza, A. Habib, and G. A. FitzGerald (1999)
J. Biol. Chem. 274, 12774-12779
 |  Abstract »  |  Full Text »  |  PDF »

Troponin I Degradation and Covalent Complex Formation Accompanies Myocardial Ischemia/Reperfusion Injury.

J. L. McDonough, D. K. Arrell, and J. E. Van Eyk (1999)
Circ. Res. 84, 9-20
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of 101-kDa Transglutaminase from Physarum polycephalum and Identification of LAV1-2 as Substrate.

J. Mottahedeh and R. Marsh (1998)
J. Biol. Chem. 273, 29888-29895
 |  Abstract »  |  Full Text »  |  PDF »

Prolonged Depletion of Guanosine Triphosphate Induces Death of Insulin-Secreting Cells by Apoptosis.

G. Li, V. B. G. Segu, M. E. Rabaglia, R.-H. Luo, A. Kowluru, and S. A. Metz (1998)
Endocrinology 139, 3752-3762
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Transforming Growth Factor-beta 1/Bone Morphogenetic Protein 4 (TGF-beta 1/BMP4) Response Element within the Mouse Tissue Transglutaminase Gene Promoter.

S. J. Ritter and P. J. A. Davies (1998)
J. Biol. Chem. 273, 12798-12806
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Nuclear Localization and Activity of Tissue Transglutaminase.

M. Lesort, K. Attanavanich, J. Zhang, and G. V. W. Johnson (1998)
J. Biol. Chem. 273, 11991-11994
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for the Involvement of Both Retinoic Acid Receptor- and Retinoic X Receptor-Dependent Signaling Pathways in the Induction of Tissue Transglutaminase and Apoptosis in the Human Myeloma Cell Line RPMI 8226 .

B. Joseph, O. Lefebvre, C. Mereau-Richard, P.-M. Danze, M.-T. Belin-Plancot, and P. Formstecher (1998)
Blood 91, 2423-2432
 |  Abstract »  |  Full Text »  |  PDF »

The Intermediate Filament Protein, Vimentin, in the Lens Is a Target for Cross-linking by Transglutaminase.

S. Clement, P. T. Velasco, S. N. P. Murthy, J. H. Wilson, T. J. Lukas, R. D. Goldman, and L. Lorand (1998)
J. Biol. Chem. 273, 7604-7609
 |  Abstract »  |  Full Text »  |  PDF »

Isolation of a cDNA Encoding a Novel Member of the Transglutaminase Gene Family from Human Keratinocytes. DETECTION AND IDENTIFICATION OF TRANSGLUTAMINASE GENE PRODUCTS BASED ON REVERSE TRANSCRIPTION-POLYMERASE CHAIN REACTION WITH DEGENERATE PRIMERS.

D. Aeschlimann, M. K. Koeller, B. L. Allen-Hoffmann, and D. F. Mosher (1998)
J. Biol. Chem. 273, 3452-3460
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the Eukaryotic Initiation Factor 5A as a Retinoic Acid-stimulated Cellular Binding Partner for Tissue Transglutaminase II.

U. S. Singh, Q. Li, and R. Cerione (1998)
J. Biol. Chem. 273, 1946-1950
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of the in Situ Activity of Tissue Transglutaminase by Calcium and GTP.

J. Zhang, M. Lesort, R. P. Guttmann, and G. V. W. Johnson (1998)
J. Biol. Chem. 273, 2288-2295
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Regulation of Human Tissue Transglutaminase Function by Magnesium-Nucleotide Complexes. IDENTIFICATION OF DISTINCT BINDING SITES FOR Mg-GTP AND Mg-ATP.

T.-S. Lai, T. F. Slaughter, K. A. Peoples, J. M. Hettasch, and C. S. Greenberg (1998)
J. Biol. Chem. 273, 1776-1781
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Sphingosylphosphocholine Reduces the Calcium Ion Requirement for Activating Tissue Transglutaminase.

T.-S. Lai, A. Bielawska, K. A. Peoples, Y. A. Hannun, and C. S. Greenberg (1997)
J. Biol. Chem. 272, 16295-16300
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Identification and Characterization of a Calmodulin-binding Domain in Ral-A, a Ras-related GTP-binding Protein Purified from Human Erythrocyte Membrane.

K. L. Wang, M. T. Khan, and B. D. Roufogalis (1997)
J. Biol. Chem. 272, 16002-16009
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Regulation of Phosphoinositide-specific Phospholipase C Isozymes.

S. G. Rhee and Y. S. Bae (1997)
J. Biol. Chem. 272, 15045-15048
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Dimerization of Midkine by Tissue Transglutaminase and Its Functional Implication.

S. Kojima, T. Inui, H. Muramatsu, Y. Suzuki, K. Kadomatsu, M. Yoshizawa, S. Hirose, T. Kimura, S. Sakakibara, and T. Muramatsu (1997)
J. Biol. Chem. 272, 9410-9416
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Phospholipase Cgamma activation and phosphoinositide hydrolysis are essential for embryonal development.

J. Schlessinger (1997)
PNAS 94, 2798-2799
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Expression of GTP-dependent and GTP-independent Tissue-type Transglutaminase in Cytokine-treated Rat Brain Astrocytes.

A. Monsonego, Y. Shani, I. Friedmann, Y. Paas, O. Eizenberg, and M. Schwartz (1997)
J. Biol. Chem. 272, 3724-3732
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Reduced expression of tissue transglutaminase in a human endothelial cell line leads to changes in cell spreading, cell adhesion and reduced polymerisation of fibronectin.

R. Jones, B Nicholas, S Mian, P. Davies, and M Griffin (1997)
J. Cell Sci. 110, 2461-2472
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alpha 1-Adrenergic Receptor Signaling via Gh Is Subtype Specific and Independent of Its Transglutaminase Activity.

S. Chen, F. Lin, S. Iismaa, K. N. Lee, P. J. Birckbichler, and R. M. Graham (1996)
J. Biol. Chem. 271, 32385-32391
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Neurodegenerative diseases and transglutaminase.

L. Lorand (1996)
PNAS 93, 14310-14313
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C-terminal Deletion of Human Tissue Transglutaminase Enhances Magnesium-dependent GTP/ATPase Activity.

T.-S. Lai, T. F. Slaughter, C. M. Koropchak, Z. A. Haroon, and C. S. Greenberg (1996)
J. Biol. Chem. 271, 31191-31195
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Biochemical Effects of Retinoic Acid on GTP-binding Protein/Transglutaminases in HeLa Cells. STIMULATION OF GTP-BINDING AND TRANSGLUTAMINASE ACTIVITY, MEMBRANE ASSOCIATION, AND PHOSPHATIDYLINOSITOL LIPID TURNOVER.

U. S. Singh and R. A. Cerione (1996)
J. Biol. Chem. 271, 27292-27298
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The Transglutaminase 1Enzyme Is Variably Acylated by Myristate and Palmitate during Differentiation in Epidermal Keratinocytes.

P. M. Steinert, S.-Y. Kim, S.-I. Chung, and L. N. Marekov (1996)
J. Biol. Chem. 271, 26242-26250
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Multifunctional G Proteins: Searching for Functions in the Heart.

G. L. Stiles (1996)
Circulation 94, 602-603
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{alpha}1-Adrenergic Receptor Coupling With Gh in the Failing Human Heart.

K.-C. Hwang, C. D. Gray, W. E. Sweet, C. S. Moravec, and M.-J. Im (1996)
Circulation 94, 718-726
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Evidence That Phospholipase delta 1 Is the Effector in the Gh (Transglutaminase II)-mediated Signaling.

J.-F. Feng, S. G. Rhee, and M.-J. Im (1996)
J. Biol. Chem. 271, 16451-16454
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{alpha}1-Adrenergic Receptor Subtypes : Molecular Structure, Function, and Signaling.

R. M. Graham, D. M. Perez, J. Hwa, and M. T. Piascik (1996)
Circ. Res. 78, 737-749
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Identification and Characterization of a Versatile Retinoid Response Element (Retinoic Acid Receptor Response Element-Retinoid X Receptor Response Element) in the Mouse Tissue Transglutaminase Gene Promoter.

L. Nagy, M. Saydak, N. Shipley, S. Lu, J. P. Basilion, Z. H. Yan, P. Syka, R. A. S. Chandraratna, J. P. Stein, R. A. Heyman, et al. (1996)
J. Biol. Chem. 271, 4355-4365
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Interaction Site of GTP Binding G(h) (Transglutaminase II) with Phospholipase C.

K.-C. Hwang, C. D. Gray, N. Sivasubramanian, and M.-J. Im (1995)
J. Biol. Chem. 270, 27058-27062
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