Science 1 April 1994: Vol. 264. no. 5155, pp. 101 - 104 DOI: 10.1126/science.8140412

Prev | Table of Contents | Next

Articles

Trps1 Functions Downstream of Bmp7 in Kidney Development.

Z. Gai, G. Zhou, S. Itoh, Y. Morimoto, H. Tanishima, I. Hatamura, K. Uetani, M. Ito, and Y. Muragaki (2009)
J. Am. Soc. Nephrol. 20, 2403-2411
 |  Abstract »  |  Full Text »  |  PDF »

Dominant-Negative ALK2 Allele Associates With Congenital Heart Defects.

K. A. Smith, I. C. Joziasse, S. Chocron, M. van Dinther, V. Guryev, M. C. Verhoeven, H. Rehmann, J. J. van der Smagt, P. A. Doevendans, E. Cuppen, et al. (2009)
Circulation 119, 3062-3069
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Bone Morphogenetic Protein Receptor (BMPR) during Perinatal Ovary Development and Primordial Follicle Formation in the Hamster: Possible Regulation by FSH.

C. Wang and S. K. Roy (2009)
Endocrinology 150, 1886-1896
 |  Abstract »  |  Full Text »  |  PDF »

Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways..

M. Murakami, H. Kawachi, K. Ogawa, Y. Nishino, and M. Funaba (2009)
Genes Cells 14, 469-482
 |  Abstract »  |  Full Text »  |  PDF »

Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes.

M. Asai-Coakwell, C. R. French, M. Ye, K. Garcha, K. Bigot, A. G. Perera, K. Staehling-Hampton, S. C. Mema, B. Chanda, A. Mushegian, et al. (2009)
Hum. Mol. Genet. 18, 1110-1121
 |  Abstract »  |  Full Text »  |  PDF »

Review of the activation of TGF-{beta} in immunity.

A. W. Taylor (2009)
J. Leukoc. Biol. 85, 29-33
 |  Abstract »  |  Full Text »  |  PDF »

Transforming Growth Factor {beta}-Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth.

A. C. Daly, R. A. Randall, and C. S. Hill (2008)
Mol. Cell. Biol. 28, 6889-6902
 |  Abstract »  |  Full Text »  |  PDF »

Structure Analysis of Bone Morphogenetic Protein-2 Type I Receptor Complexes Reveals a Mechanism of Receptor Inactivation in Juvenile Polyposis Syndrome.

A. Kotzsch, J. Nickel, A. Seher, K. Heinecke, L. van Geersdaele, T. Herrmann, W. Sebald, and T. D. Mueller (2008)
J. Biol. Chem. 283, 5876-5887
 |  Abstract »  |  Full Text »  |  PDF »

Cripto Is a Noncompetitive Activin Antagonist That Forms Analogous Signaling Complexes with Activin and Nodal.

J. A. Kelber, G. Shani, E. C. Booker, W. W. Vale, and P. C. Gray (2008)
J. Biol. Chem. 283, 4490-4500
 |  Abstract »  |  Full Text »  |  PDF »

Functional Characterization of Bone Morphogenetic Protein Binding Sites and Smad1/5 Activation in Human Vascular Cells.

P. D. Upton, L. Long, R. C. Trembath, and N. W. Morrell (2008)
Mol. Pharmacol. 73, 539-552
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms for Asporin Function and Regulation in Articular Cartilage.

M. Nakajima, H. Kizawa, M. Saitoh, I. Kou, K. Miyazono, and S. Ikegawa (2007)
J. Biol. Chem. 282, 32185-32192
 |  Abstract »  |  Full Text »  |  PDF »

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis.

M. Scharpfenecker, M. van Dinther, Z. Liu, R.L. van Bezooijen, Q. Zhao, L. Pukac, C. W. G. M. Lowik, and P. ten Dijke (2007)
J. Cell Sci. 120, 964-972
 |  Abstract »  |  Full Text »  |  PDF »

Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells.

L. David, C. Mallet, S. Mazerbourg, J.-J. Feige, and S. Bailly (2007)
Blood 109, 1953-1961
 |  Abstract »  |  Full Text »  |  PDF »

The structural basis of TGF-{beta}, bone morphogenetic protein, and activin ligand binding..

S J. Lin, T. F Lerch, R. W Cook, T. S Jardetzky, and T. K Woodruff (2006)
Reproduction 132, 179-190
 |  Abstract »  |  Full Text »  |  PDF »

Genomic analyses facilitate identification of receptors and signalling pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein/growth differentiation factor ligands.

S. Mazerbourg and A. J.W. Hsueh (2006)
Hum. Reprod. Update 12, 373-383
 |  Abstract »  |  Full Text »  |  PDF »

Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease.

S A Abdalla and M Letarte (2006)
J. Med. Genet. 43, 97-110
 |  Abstract »  |  Full Text »  |  PDF »

The contribution of transforming growth factor-{beta} and epidermal growth factor signalling to airway remodelling in chronic asthma.

C. Boxall, S. T. Holgate, and D. E. Davies (2006)
Eur. Respir. J. 27, 208-229
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of furin-like proprotein convertases in the arterial response to injury.

J. P.G. Sluijter, R. E. Verloop, W. P.C. Pulskens, E. Velema, J. M. Grimbergen, P. H. Quax, M.-J. Goumans, G. Pasterkamp, and D. P.V. de Kleijn (2005)
Cardiovasc Res 68, 136-143
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Receptors and Signaling Pathways for Orphan Bone Morphogenetic Protein/Growth Differentiation Factor Ligands Based on Genomic Analyses.

S. Mazerbourg, K. Sangkuhl, C.-W. Luo, S. Sudo, C. Klein, and A. J. W. Hsueh (2005)
J. Biol. Chem. 280, 32122-32132
 |  Abstract »  |  Full Text »  |  PDF »

Variation in pituitary expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and type-I and type-II activin receptors during the chicken ovulatory cycle.

T M Lovell, P G Knight, and R T Gladwell (2005)
J. Endocrinol. 186, 447-455
 |  Abstract »  |  Full Text »  |  PDF »

BMP-4 inhibits follicle-stimulating hormone secretion in ewe pituitary.

M-O Faure, L Nicol, S Fabre, J Fontaine, N Mohoric, A McNeilly, and C Taragnat (2005)
J. Endocrinol. 186, 109-121
 |  Abstract »  |  Full Text »  |  PDF »

Bone Morphogenetic Protein (BMP) Type II Receptor Deletion Reveals BMP Ligand-specific Gain of Signaling in Pulmonary Artery Smooth Muscle Cells.

P. B. Yu, H. Beppu, N. Kawai, E. Li, and K. D. Bloch (2005)
J. Biol. Chem. 280, 24443-24450
 |  Abstract »  |  Full Text »  |  PDF »

BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways.

T. K. Jeffery, P. D. Upton, R. C. Trembath, and N. W. Morrell (2005)
Am J Physiol Lung Cell Mol Physiol 288, L370-L378
 |  Abstract »  |  Full Text »  |  PDF »

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation.

A. Wilson, M. J. Murphy, T. Oskarsson, K. Kaloulis, M. D. Bettess, G. M. Oser, A.-C. Pasche, C. Knabenhans, H. R. MacDonald, and A. Trumpp (2004)
Genes & Dev. 18, 2747-2763
 |  Abstract »  |  Full Text »  |  PDF »

The Bone Morphogenetic Protein Type Ib Receptor Is a Major Mediator of Glial Differentiation and Cell Survival in Adult Hippocampal Progenitor Cell Culture.

A. Brederlau, R. Faigle, M. Elmi, A. Zarebski, S. Sjoberg, M. Fujii, K. Miyazono, and K. Funa (2004)
Mol. Biol. Cell 15, 3863-3875
 |  Abstract »  |  Full Text »  |  PDF »

Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells.

V. Kaartinen, M. Dudas, A. Nagy, S. Sridurongrit, M. M. Lu, and J. A. Epstein (2004)
Development 131, 3481-3490
 |  Abstract »  |  Full Text »  |  PDF »

Receptor Internalization-Independent Activation of Smad2 in Activin Signaling.

Y. Zhou, S. Scolavino, S. F. Funderburk, L. F. Ficociello, X. Zhang, and A. Klibanski (2004)
Mol. Endocrinol. 18, 1818-1826
 |  Abstract »  |  Full Text »  |  PDF »

Activin A in the Regulation of Corneal Neovascularization and Vascular Endothelial Growth Factor Expression.

V. Poulaki, N. Mitsiades, F. E. Kruse, S. Radetzky, E. Iliaki, B. Kirchhof, and A. M. Joussen (2004)
Am. J. Pathol. 164, 1293-1302
 |  Abstract »  |  Full Text »  |  PDF »

The Bone Morphogenetic Protein System In Mammalian Reproduction.

S. Shimasaki, R. K. Moore, F. Otsuka, and G. F. Erickson (2004)
Endocr. Rev. 25, 72-101
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Activation of Mouse Mast Cell Protease-7 by Activin and Transforming Growth Factor-{beta} Is Inhibited by Microphthalmia-associated Transcription Factor.

M. Funaba, T. Ikeda, M. Murakami, K. Ogawa, K. Tsuchida, H. Sugino, and M. Abe (2003)
J. Biol. Chem. 278, 52032-52041
 |  Abstract »  |  Full Text »  |  PDF »

Spatial Expression Patterns of Activin and Its Signaling System in the Zebrafish Ovarian Follicle: Evidence for Paracrine Action of Activin on the Oocytes.

Y. Wang and W. Ge (2003)
Biol Reprod 69, 1998-2006
 |  Abstract »  |  Full Text »  |  PDF »

SB-431542 and Gleevec Inhibit Transforming Growth Factor-{beta}-Induced Proliferation of Human Osteosarcoma Cells.

S. Matsuyama, M. Iwadate, M. Kondo, M. Saitoh, A. Hanyu, K. Shimizu, H. Aburatani, H. K. Mishima, T. Imamura, K. Miyazono, et al. (2003)
Cancer Res. 63, 7791-7798
 |  Abstract »  |  Full Text »  |  PDF »

Arterial Endothelium-Specific Activin Receptor-Like Kinase 1 Expression Suggests Its Role in Arterialization and Vascular Remodeling.

T. Seki, J. Yun, and S. P. Oh (2003)
Circ. Res. 93, 682-689
 |  Abstract »  |  Full Text »  |  PDF »

cGMP/Protein Kinase G-Dependent Potentiation of Glutamatergic Transmission Induced by Nitric Oxide in Immature Rat Rostral Ventrolateral Medulla Neurons in Vitro.

C.-C. Huang, S. H. H. Chan, and K.-S. Hsu (2003)
Mol. Pharmacol. 64, 521-532
 |  Abstract »  |  Full Text »  |  PDF »

Normal Reproductive Function in InhBP/p120-Deficient Mice.

D. J. Bernard, K. H. Burns, B. Haupt, M. M. Matzuk, and T. K. Woodruff (2003)
Mol. Cell. Biol. 23, 4882-4891
 |  Abstract »  |  Full Text »  |  PDF »

Induction of the Sry-Related Factor SOX6 Contributes to Bone Morphogenetic Protein-2-Induced Chondroblastic Differentiation of C3H10T1/2 Cells.

R. Fernandez-Lloris, F. Vinals, T. Lopez-Rovira, V. Harley, R. Bartrons, J. L. Rosa, and F. Ventura (2003)
Mol. Endocrinol. 17, 1332-1343
 |  Abstract »  |  Full Text »  |  PDF »

Vascular morphogenesis: tales of two syndromes.

D. A. Marchuk, S. Srinivasan, T. L. Squire, and J. S. Zawistowski (2003)
Hum. Mol. Genet. 12, R97-112
 |  Abstract »  |  Full Text »  |  PDF »

Kruppel-like Factor 4 (KLF4/GKLF) Is a Target of Bone Morphogenetic Proteins and Transforming Growth Factor beta 1 in the Regulation of Vascular Smooth Muscle Cell Phenotype.

K. E. King, V. P. Iyemere, P. L. Weissberg, and C. M. Shanahan (2003)
J. Biol. Chem. 278, 11661-11669
 |  Abstract »  |  Full Text »  |  PDF »

Autocrine Transforming Growth Factor-beta Signaling Mediates Smad-independent Motility in Human Cancer Cells.

N. Dumont, A. V. Bakin, and C. L. Arteaga (2003)
J. Biol. Chem. 278, 3275-3285
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of ALK-1 Signaling by the Nuclear Receptor LXRbeta.

J. Mo, S. J. Fang, W. Chen, and G. C. Blobe (2002)
J. Biol. Chem. 277, 50788-50794
 |  Abstract »  |  Full Text »  |  PDF »

Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis.

S. Lamouille, C. Mallet, J.-J. Feige, and S. Bailly (2002)
Blood 100, 4495-4501
 |  Abstract »  |  Full Text »  |  PDF »

Transforming Growth Factor beta (TGFbeta ) Signaling via Differential Activation of Activin Receptor-like Kinases 2 and 5 during Cardiac Development. ROLE IN REGULATING PARASYMPATHETIC RESPONSIVENESS.

S. M. Ward, J. S. Desgrosellier, X. Zhuang, J. V. Barnett, and J. B. Galper (2002)
J. Biol. Chem. 277, 50183-50189
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Analysis of the Mammalian Transforming Growth Factor-{beta} Superfamily.

H. Chang, C. W. Brown, and M. M. Matzuk (2002)
Endocr. Rev. 23, 787-823
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Activation of the BMP-Signaling Components in Human Fracture Nonunions.

P. Kloen, S. B. Doty, E. Gordon, I. F. Rubel, M.-J. Goumans, and D. L. Helfet (2002)
J. Bone Joint Surg. Am. 84, 1909-1918
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of Smad2-mediated Signaling by Extracellular Signal-regulated Kinase.

M. Funaba, C. M. Zimmerman, and L. S. Mathews (2002)
J. Biol. Chem. 277, 41361-41368
 |  Abstract »  |  Full Text »  |  PDF »

Functional Heterogeneity of Bone Morphogenetic Protein Receptor-II Mutants Found in Patients with Primary Pulmonary Hypertension.

A. Nishihara, T. Watabe, T. Imamura, and K. Miyazono (2002)
Mol. Biol. Cell 13, 3055-3063
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Bone Morphogenetic Protein/Smad Signaling in Bronchial Epithelial Cells during Airway Inflammation.

A. Rosendahl, E. Pardali, M. Speletas, P. ten Dijke, C.-H. Heldin, and P. Sideras (2002)
Am. J. Respir. Cell Mol. Biol. 27, 160-169
 |  Abstract »  |  Full Text »  |  PDF »

SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-beta Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7.

G. J. Inman, F. J. Nicolas, J. F. Callahan, J. D. Harling, L. M. Gaster, A. D. Reith, N. J. Laping, and C. S. Hill (2002)
Mol. Pharmacol. 62, 65-74
 |  Abstract »  |  Full Text »  |  PDF »

Transforming growth factor {beta} signal transduction.

S. Dennler, M.-J. Goumans, and P. ten Dijke (2002)
J. Leukoc. Biol. 71, 731-740
 |  Abstract »  |  Full Text »  |  PDF »

Differential Effect of Activin A and BMP-7 on Myofibroblast Differentiation and the Role of the Smad Signaling Pathway.

L. You and F. E. Kruse (2002)
Invest. Ophthalmol. Vis. Sci. 43, 72-81
 |  Abstract »  |  Full Text »  |  PDF »

Autosomal Recessive Segregation of a Truncating Mutation of Anti-Mullerian Type II Receptor in a Family Affected by the Persistent Mullerian Duct Syndrome Contrasts with Its Dominant Negative Activity in Vitro.

L. Messika-Zeitoun, L. Gouedard, C. Belville, M. Dutertre, L. Lins, S. Imbeaud, I. A. Hughes, J.-Y. Picard, N. Josso, and N. di Clemente (2001)
J. Clin. Endocrinol. Metab. 86, 4390-4397
 |  Abstract »  |  Full Text »  |  PDF »

The Serine/Threonine Transmembrane Receptor ALK2 Mediates Mullerian Inhibiting Substance Signaling.

J. A. Visser, R. Olaso, M. Verhoef-Post, P. Kramer, A. P. N. Themmen, and H. A. Ingraham (2001)
Mol. Endocrinol. 15, 936-945
 |  Abstract »  |  Full Text »  |  PDF »

Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons.

C.-C. Huang, S.-W. Lo, and K.-S. Hsu (2001)
J. Physiol. 532, 731-748
 |  Abstract »  |  Full Text »  |  PDF »

The Crystal Structure of the BMP-2:BMPR-IA Complex and the Generation of BMP-2 Antagonists.

J. Nickel, M. K. Dreyer, T. Kirsch, and W. Sebald (2001)
J. Bone Joint Surg. Am. 83, S7-14
 |  Abstract »  |  Full Text »  |  PDF »

The Crystal Structure of the BMP-2:BMPR-IA Complex and the Generation of BMP-2 Antagonists.

J. Nickel, M. K. Dreyer, T. Kirsch, and W. Sebald (2001)
J. Bone Joint Surg. Am. 83, S7-S14
 |  Abstract »  |  Full Text »  |  PDF »

Truncated Activin Type I Receptor Alk4 Isoforms Are Dominant Negative Receptors Inhibiting Activin Signaling.

Y. Zhou, H. Sun, D. C. Danila, S. R. Johnson, D. P. Sigai, X. Zhang, and A. Klibanski (2000)
Mol. Endocrinol. 14, 2066-2075
 |  Abstract »  |  Full Text »

Smad7 selectively interferes with different pathways of activin signaling and inhibits erythroid leukemia cell differentiation.

K. Kitamura, S.-i. Aota, R. Sakamoto, S.-I. Yoshikawa, and K. Okazaki (2000)
Blood 95, 3371-3379
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of ALK-1 and endoglin in newborns from families with hereditary hemorrhagic telangiectasia type 2.

S. A. Abdalla, N. Pece-Barbara, S. Vera, E. Tapia, E. Paez, C. Bernabeu, and M. Letarte (2000)
Hum. Mol. Genet. 9, 1227-1237
 |  Abstract »  |  Full Text »  |  PDF »

Synergy of Activin and Ciliary Neurotrophic Factor Signaling Pathways in the Induction of Vasoactive Intestinal Peptide Gene Expression.

A. J. Symes, R. L. Pitts, J. Conover, K. Kos, and J. Coulombe (2000)
Mol. Endocrinol. 14, 429-439
 |  Abstract »  |  Full Text »

Hereditary Hemorrhagic Telangiectasia : A Model for Blood Vessel Growth and Enlargement.

B. S. Jacobson (2000)
Am. J. Pathol. 156, 737-742
 |  Full Text »  |  PDF »

A Caenorhabditis elegans type I TGF beta receptor can function in the absence of type II kinase to promote larval development.

C. Gunther, L. Georgi, and D. Riddle (2000)
Development 127, 3337-3347
 |  Abstract »  |  PDF »

Specificity, diversity, and regulation in TGF-{beta} superfamily signaling.

E. PIEK, C.-H. HELDIN, and P. TEN DIJKE (1999)
FASEB J 13, 2105-2124
 |  Abstract »  |  Full Text »

Human Ovarian Cancer, Cell Lines, and Primary Ascites Cells Express the Human Mullerian Inhibiting Substance (MIS) Type II Receptor, Bind, and Are Responsive to MIS.

P. T. Masiakos, D. T. MacLaughlin, S. Maheswaran, J. Teixeira, A. F. Fuller Jr., P. C. Shah, D. J. Kehas, M. K. Kenneally, D. M. Dombkowski, T. U. Ha, et al. (1999)
Clin. Cancer Res. 5, 3488-3499
 |  Abstract »  |  Full Text »  |  PDF »

Roles of Bone Morphogenetic Protein Type I Receptors and Smad Proteins in Osteoblast and Chondroblast Differentiation.

M. Fujii, K. Takeda, T. Imamura, H. Aoki, T. K. Sampath, S. Enomoto, M. Kawabata, M. Kato, H. Ichijo, and K. Miyazono (1999)
Mol. Biol. Cell 10, 3801-3813
 |  Abstract »  |  Full Text »

In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: A potential new therapy for hepatic fibrosis.

J. George, D. Roulot, V. E. Koteliansky, and D. M. Bissell (1999)
PNAS 96, 12719-12724
 |  Abstract »  |  Full Text »  |  PDF »

Rare diseases bullet 4: Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations: issues in clinical management and review of pathogenic mechanisms.

C. L Shovlin and M. Letarte (1999)
Thorax 54, 714-729
 |  Full Text »

Molecular Evolution of a Developmental Pathway: Phylogenetic Analyses of Transforming Growth Factor-ß Family Ligands, Receptors and Smad Signal Transducers.

S. J. Newfeld, R. G. Wisotzkey, and S. Kumar (1999)
Genetics 152, 783-795
 |  Abstract »  |  Full Text »

Assignment of Transforming Growth Factor beta 1 and beta 3 and a Third New Ligand to the Type I Receptor ALK-1.

A. Lux, L. Attisano, and D. A. Marchuk (1999)
J. Biol. Chem. 274, 9984-9992
 |  Abstract »  |  Full Text »  |  PDF »

Smad1 Recognition and Activation by the ALK1 Group of Transforming Growth Factor-beta Family Receptors.

Y.-G. Chen and J. Massague (1999)
J. Biol. Chem. 274, 3672-3677
 |  Abstract »  |  Full Text »  |  PDF »

TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells.

E Piek, A Moustakas, A Kurisaki, C. Heldin, and P ten Dijke (1999)
J. Cell Sci. 112, 4557-4568
 |  Abstract »  |  PDF »

Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation.

T Ebisawa, K Tada, I Kitajima, K Tojo, T. Sampath, M Kawabata, K Miyazono, and T Imamura (1999)
J. Cell Sci. 112, 3519-3527
 |  Abstract »  |  PDF »

Endoglin Is an Accessory Protein That Interacts with the Signaling Receptor Complex of Multiple Members of the Transforming Growth Factor-beta Superfamily.

N. P. Barbara, J. L. Wrana, and M. Letarte (1999)
J. Biol. Chem. 274, 584-594
 |  Abstract »  |  Full Text »  |  PDF »

The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo.

Z Gu, E. Reynolds, J Song, H Lei, A Feijen, L Yu, W He, D. MacLaughlin, J van den Eijnden-van Raaij, P. Donahoe, et al. (1999)
Development 126, 2551-2561
 |  Abstract »  |  PDF »

BMP Receptors in Limb and Tooth Formation.

S. Cheifetz (1999)
Critical Reviews in Oral Biology & Medicine 10, 182-198
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and characterization of a naturally occurring soluble form of TGF-beta type I receptor.

M. E. Choi (1999)
Am J Physiol Renal Physiol 276, F88-F95
 |  Abstract »  |  Full Text »  |  PDF »

Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2.

M. Macias-Silva, P. A. Hoodless, S. J. Tang, M. Buchwald, and J. L. Wrana (1998)
J. Biol. Chem. 273, 25628-25636
 |  Abstract »  |  Full Text »  |  PDF »

Smad7 Is an Activin-inducible Inhibitor of Activin-induced Growth Arrest and Apoptosis in Mouse B Cells.

A. Ishisaki, K. Yamato, A. Nakao, K. Nonaka, M. Ohguchi, P. ten Dijke, and T. Nishihara (1998)
J. Biol. Chem. 273, 24293-24296
 |  Abstract »  |  Full Text »  |  PDF »

Determinants of specificity in TGF-beta signal transduction.

Y.-G. Chen, A. Hata, R. S. Lo, D. Wotton, Y. Shi, N. Pavletich, and J. Massagué (1998)
Genes & Dev. 12, 2144-2152
 |  Abstract »  |  Full Text »

Development of Bone Morphogenetic Protein Receptors in the Nervous System and Possible Roles in Regulating trkC Expression.

D. Zhang, M. F. Mehler, Q. Song, and J. A. Kessler (1998)
J. Neurosci. 18, 3314-3326
 |  Abstract »  |  Full Text »  |  PDF »

The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse.

Z. Gu, M. Nomura, B. B. Simpson, H. Lei, A. Feijen, J. van den Eijnden-van Raaij, P. K. Donahoe, and E. Li (1998)
Genes & Dev. 12, 844-857
 |  Abstract »  |  Full Text »

JunB Is Involved in the Inhibition of Myogenic Differentiation by Bone Morphogenetic Protein-2.

E. Chalaux, T. Lopez-Rovira, J. L. Rosa, R. Bartrons, and F. Ventura (1998)
J. Biol. Chem. 273, 537-543
 |  Abstract »  |  Full Text »  |  PDF »

BMP-2 and OP-1 exert direct and opposite effects on renal branching morphogenesis.

T. D. Piscione, T. D. Yager, I. R. Gupta, B. Grinfeld, Y. Pei, L. Attisano, J. L. Wrana, and N. D. Rosenblum (1997)
Am J Physiol Renal Physiol 273, F961-F975
 |  Abstract »  |  Full Text »  |  PDF »

Smad8 mediates the signaling of the receptor serine kinase.

Y. Chen, A. Bhushan, and W. Vale (1997)
PNAS 94, 12938-12943
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-beta Signaling.

S. Souchelnytskyi, K. Tamaki, U. Engstrom, C. Wernstedt, P. ten Dijke, and C.-H. Heldin (1997)
J. Biol. Chem. 272, 28107-28115
 |  Abstract »  |  Full Text »  |  PDF »

Osteogenic Protein-1 and Insulin-Like Growth Factor I Synergistically Stimulate Rat Osteoblastic Cell Differentiation and Proliferation.

L.-C. C. Yeh, M. L. Adamo, M. S. Olson, and J. C. Lee (1997)
Endocrinology 138, 4181-4190
 |  Abstract »  |  Full Text »  |  PDF »

Expression of TGF-{beta} Superfamily Receptors in Dental Pulp.

T. Toyono, M. Nakashima, S. Kuhara, and A. Akamine (1997)
Journal of Dental Research 76, 1555-1560
 |  Abstract »  |  PDF »

Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage.

H. Zou, R. Wieser, J. Massague, and L. Niswander (1997)
Genes & Dev. 11, 2191-2203
 |  Abstract »  |  Full Text »  |  PDF »

Transforming Growth Factor (TGF-beta )-specific Signaling by Chimeric TGF-beta Type II Receptor with Intracellular Domain of Activin Type IIB Receptor.

U. Persson, S. Souchelnytskyi, P. Franzen, K. Miyazono, P. ten Dijke, and C.-H. Heldin (1997)
J. Biol. Chem. 272, 21187-21194
 |  Abstract »  |  Full Text »  |  PDF »

The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse..

S P Oh and E Li (1997)
Genes & Dev. 11, 1812-1826
 |  Abstract »  |  PDF »

Inhibin Interferes with Activin Signaling at the Level of the Activin Receptor Complex in Chinese Hamster Ovary Cells.

J. W. M. Martens, J. P. de Winter, M. A. Timmerman, A. McLuskey, R. H. N. van Schaik, A. P. N. Themmen, and F. H. de Jong (1997)
Endocrinology 138, 2928-2936
 |  Abstract »  |  Full Text »  |  PDF »

The Type II Transforming Growth Factor-beta Receptor Autophosphorylates Not Only on Serine and Threonine but Also on Tyrosine Residues.

S. Lawler, X.-H. Feng, R.-H. Chen, E. M. Maruoka, C. W. Turck, I. Griswold-Prenner, and R. Derynck (1997)
J. Biol. Chem. 272, 14850-14859
 |  Abstract »  |  Full Text »  |  PDF »

Bovine Activin Receptor Type IIB Messenger Ribonucleic Acid Displays Alternative Splicing Involving a Sequence Homologous to Src-Homology 3 domain Binding Sites.

J.-F. Ethier, J. G. Lussier, and D. W. Silversides (1997)
Endocrinology 138, 2425-2434
 |  Abstract »  |  Full Text »  |  PDF »

Loss of functional cell surface transforming growth factor beta  (TGF-beta ) type 1 receptor correlates with insensitivity to TGF-beta in chronic lymphocytic leukemia.

J. F. DeCoteau, P. I. Knaus, H. Yankelev, M. D. Reis, R. Lowsky, H. F. Lodish, and M. E. Kadin (1997)
PNAS 94, 5877-5881
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Smad2, a Human Mad-related Protein in the Transforming Growth Factor beta Signaling Pathway.

A. Nakao, E. Roijer, T. Imamura, S. Souchelnytskyi, G. Stenman, C.-H. Heldin, and P. ten Dijke (1997)
J. Biol. Chem. 272, 2896-2900
 |  Abstract »  |  Full Text »  |  PDF »

Patterning the Xenopus blastula.

J Heasman (1997)
Development 124, 4179-4191
 |  Abstract »  |  PDF »

A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis.

C Chang, P. Wilson, L. Mathews, and A Hemmati-Brivanlou (1997)
Development 124, 827-837
 |  Abstract »  |  PDF »

A Novel Type I Receptor Serine-Threonine Kinase Predominantly Expressed in the Adult Central Nervous System.

M. Ryden, T. Imamura, H. Jornvall, N. Belluardo, I. Neveu, M. Trupp, T. Okadome, P. ten Dijke, and C. F. Ibanez (1996)
J. Biol. Chem. 271, 30603-30609
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Type I and Type II Serine/Threonine Kinase Receptors for Growth/Differentiation Factor-5.

H. Nishitoh, H. Ichijo, M. Kimura, T. Matsumoto, F. Makishima, A. Yamaguchi, H. Yamashita, S. Enomoto, and K. Miyazono (1996)
J. Biol. Chem. 271, 21345-21352
 |  Abstract »  |  Full Text »  |  PDF »

Adenovirus-mediated Transfer of a Truncated Transforming Growth Factor-beta (TGF-beta ) Type II Receptor Completely and Specifically Abolishes Diverse Signaling by TGF-beta in Vascular Wall Cells in Primary Culture.

H. Yamamoto, H. Ueno, A. Ooshima, and A. Takeshita (1996)
J. Biol. Chem. 271, 16253-16259
 |  Abstract »  |  Full Text »  |  PDF »

Ligand-independent Activation of Transforming Growth Factor (TGF) beta Signaling Pathways by Heteromeric Cytoplasmic Domains of TGF-beta Receptors.

X.-H. Feng and R. Derynck (1996)
J. Biol. Chem. 271, 13123-13129
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products