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Science 25 March 1994:
Vol. 263. no. 5154, pp. 1771 - 1774
DOI: 10.1126/science.8134840
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Articles

Science, Vol 263, Issue 5154, 1771-1774
Copyright © 1994 by American Association for the Advancement of Science

articles

Genetic mapping of quantitative trait loci for growth and fatness in pigs

L Andersson, CS Haley, H Ellegren, SA Knott, M Johansson, K Andersson, L Andersson-Eklund, I Edfors-Lilja, M Fredholm, I Hansson, and al. et

Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala.

The European wild boar was crossed with the domesticated Large White pig to genetically dissect phenotypic differences between these populations for growth and fat deposition. The most important effects were clustered on chromosome 4, with a single region accounting for a large part of the breed difference in growth rate, fatness, and length of the small intestine. The study is an advance in genome analyses and documents the usefulness of crosses between divergent outbred populations for the detection and characterization of quantitative trait loci. The genetic mapping of a major locus for fat deposition in the pig could have implications for understanding human obesity.


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