Science 18 March 1994: Vol. 263. no. 5153, pp. 1612 - 1615 DOI: 10.1126/science.7510419

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Articles

Inducible Nitric-oxide Synthase Expression Is Regulated by Mitogen-activated Protein Kinase Phosphatase-1.

X. Wang, Q. Zhao, R. Matta, X. Meng, X. Liu, C.-G. Liu, L. D. Nelin, and Y. Liu (2009)
J. Biol. Chem. 284, 27123-27134
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic Induction of Endothelin-1 by Tumor Necrosis Factor {alpha} and Interferon {gamma} Is due to Enhanced NF-{kappa}B Binding and Histone Acetylation at Specific {kappa}B Sites.

S. J. Wort, M. Ito, P.-C. Chou, S. K. Mc Master, R. Badiger, E. Jazrawi, P. de Souza, T. W. Evans, J. A. Mitchell, L. Pinhu, et al. (2009)
J. Biol. Chem. 284, 24297-24305
 |  Abstract »  |  Full Text »  |  PDF »

Induction of iNOS by Chlamydophila pneumoniae requires MyD88-dependent activation of JNK.

N. Rodriguez, R. Lang, N. Wantia, C. Cirl, T. Ertl, S. Durr, H. Wagner, and T. Miethke (2008)
J. Leukoc. Biol. 84, 1585-1593
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{gamma}-Induced TNF-{alpha} Expression Is Regulated by Interferon Regulatory Factors 1 and 8 in Mouse Macrophages.

V. Vila-del Sol, C. Punzon, and M. Fresno (2008)
J. Immunol. 181, 4461-4470
 |  Abstract »  |  Full Text »  |  PDF »

Toll-like receptor (TLR) 2 induced through TLR4 signaling initiated by Helicobacter pylori cooperatively amplifies iNOS induction in gastric epithelial cells.

K. Uno, K. Kato, T. Atsumi, T. Suzuki, J. Yoshitake, H. Morita, S. Ohara, Y. Kotake, T. Shimosegawa, and T. Yoshimura (2007)
Am J Physiol Gastrointest Liver Physiol 293, G1004-G1012
 |  Abstract »  |  Full Text »  |  PDF »

Fate of a Burkholderia pseudomallei Lipopolysaccharide Mutant in the Mouse Macrophage Cell Line RAW 264.7: Possible Role for the O-Antigenic Polysaccharide Moiety of Lipopolysaccharide in Internalization and Intracellular Survival.

S. Arjcharoen, C. Wikraiphat, M. Pudla, K. Limposuwan, D. E. Woods, S. Sirisinha, and P. Utaisincharoen (2007)
Infect. Immun. 75, 4298-4304
 |  Abstract »  |  Full Text »  |  PDF »

Lipopolysaccharide enhances interferon-{gamma}-induced nitric oxide (NO) production in murine vascular endothelial cells via augmentation of interferon regulatory factor-1 activation.

N. Koide, Mya Mya Mu, F. Hassan, S. Islam, G. Tumurkhuu, J. Dagvadorj, Y. Naiki, I. Mori, T. Yoshida, and T. Yokochi (2007)
Innate Immunity 13, 167-175
 |  Abstract »  |  PDF »

Requirement of tumor necrosis factor {alpha} and nuclear factor-{kappa}B in the induction by IFN-{gamma} of inducible nitric oxide synthase in macrophages.

V. Vila-del Sol, M. D. Diaz-Munoz, and M. Fresno (2007)
J. Leukoc. Biol. 81, 272-283
 |  Abstract »  |  Full Text »  |  PDF »

Essential Role of C-Rel in Nitric-Oxide Synthase-2 Transcriptional Activation: Time-Dependent Control by Salicylate.

K. A. Cieslik, W.-G. Deng, and K. K. Wu (2006)
Mol. Pharmacol. 70, 2004-2014
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for licensing of IFN-{gamma}-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.

H. Negishi, Y. Fujita, H. Yanai, S. Sakaguchi, X. Ouyang, M. Shinohara, H. Takayanagi, Y. Ohba, T. Taniguchi, and K. Honda (2006)
PNAS 103, 15136-15141
 |  Abstract »  |  Full Text »  |  PDF »

A suppressive role of nitric oxide in MIP-2 production by macrophages upon coculturing with apoptotic cells.

T. Shibata, K. Nagata, and Y. Kobayashi (2006)
J. Leukoc. Biol. 80, 744-752
 |  Abstract »  |  Full Text »  |  PDF »

Prostasin attenuates inducible nitric oxide synthase expression in lipopolysaccharide-induced urinary bladder inflammation.

L.-M. Chen, C. Wang, M. Chen, M. R. Marcello, J. Chao, L. Chao, and K. X. Chai (2006)
Am J Physiol Renal Physiol 291, F567-F577
 |  Abstract »  |  Full Text »  |  PDF »

Phosphoinositide 3-Kinase in Nitric Oxide Synthesis in Macrophage: CRITICAL DIMERIZATION OF INDUCIBLE NITRIC-OXIDE SYNTHASE.

K. Sakai, H. Suzuki, H. Oda, T. Akaike, Y. Azuma, T. Murakami, K. Sugi, T. Ito, H. Ichinose, S. Koyasu, et al. (2006)
J. Biol. Chem. 281, 17736-17742
 |  Abstract »  |  Full Text »  |  PDF »

IFN{gamma}-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice.

T. Hanada, T. Kobayashi, T. Chinen, K. Saeki, H. Takaki, K. Koga, Y. Minoda, T. Sanada, T. Yoshioka, H. Mimata, et al. (2006)
J. Exp. Med. 203, 1391-1397
 |  Abstract »  |  Full Text »  |  PDF »

Differential expression of inducible nitric oxide synthase and IL-12 between peritoneal and splenic macrophages stimulated with LPS plus IFN-{gamma} is associated with the activation of extracellular signal-related kinase.

Y.-N. Zhu, Y.-F. Yang, S. Ono, X.-G. Zhong, Y.-H. Feng, Y.-X. Ren, J. Ni, Y.-F. Fu, W. Tang, and J.-P. Zuo (2006)
Int. Immunol. 18, 981-990
 |  Abstract »  |  Full Text »  |  PDF »

The transcription factor interferon regulatory factor-1 mediates liver damage during ischemia-reperfusion injury.

A. Tsung, M. T. Stang, A. Ikeda, N. D. Critchlow, K. Izuishi, A. Nakao, M. H. Chan, G. Jeyabalan, J. H. Yim, and D. A. Geller (2006)
Am J Physiol Gastrointest Liver Physiol 290, G1261-G1268
 |  Abstract »  |  Full Text »  |  PDF »

Toll-like receptor-independent triggering of dendritic cell maturation by viruses..

C. B. Lopez, J. S. Yount, and T. M. Moran (2006)
J. Virol. 80, 3128-3134
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Requirement of norD for Brucella suis Virulence in a Murine Model of In Vitro and In Vivo Infection.

S. Loisel-Meyer, M. P. Jimenez de Bagues, E. Basseres, J. Dornand, S. Kohler, J.-P. Liautard, and V. Jubier-Maurin (2006)
Infect. Immun. 74, 1973-1976
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Inducible Nitric-Oxide Synthase Expression by (5R)-5-Hydroxytriptolide in Interferon-{gamma}- and Bacterial Lipopolysaccharide-Stimulated Macrophages.

R. Zhou, S.-X. Zheng, W. Tang, P.-L. He, X.-Y. Li, Y.-F. Yang, Y.-C. Li, J.-G. Geng, and J.-P. Zuo (2006)
J. Pharmacol. Exp. Ther. 316, 121-128
 |  Abstract »  |  Full Text »  |  PDF »

Human Serum from Patients with Septic Shock Activates Transcription Factors STAT1, IRF1, and NF-{kappa}B and Induces Apoptosis in Human Cardiac Myocytes.

A. Kumar, A. Kumar, P. Michael, D. Brabant, A. M. Parissenti, C. V. Ramana, X. Xu, and J. E. Parrillo (2005)
J. Biol. Chem. 280, 42619-42626
 |  Abstract »  |  Full Text »  |  PDF »

Interferon function is not required for recovery from a secondary poxvirus infection.

V. Panchanathan, G. Chaudhri, and G. Karupiah (2005)
PNAS 102, 12921-12926
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory Cytokines Induce Apoptosis of Corneal Endothelium through Nitric Oxide.

P. Sagoo, G. Chan, D. F. P. Larkin, and A. J. T. George (2004)
Invest. Ophthalmol. Vis. Sci. 45, 3964-3973
 |  Abstract »  |  Full Text »  |  PDF »

B Lymphocyte-Induced Maturation Protein (Blimp)-1, IFN Regulatory Factor (IRF)-1, and IRF-2 Can Bind to the Same Regulatory Sites.

T. C. Kuo and K. L. Calame (2004)
J. Immunol. 173, 5556-5563
 |  Abstract »  |  Full Text »  |  PDF »

Reduction of Nitric Oxide Synthase 2 Expression by Distamycin A Improves Survival from Endotoxemia.

R. M. Baron, I. M. Carvajal, X. Liu, R. O. Okabe, L. E. Fredenburgh, A. A. Macias, Y.-H. Chen, K. Ejima, M. D. Layne, and M. A. Perrella (2004)
J. Immunol. 173, 4147-4153
 |  Abstract »  |  Full Text »  |  PDF »

iNOS (NOS2) at a glance.

C. J. Lowenstein and E. Padalko (2004)
J. Cell Sci. 117, 2865-2867
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Toll-Like Receptor 4 Dependence of Innate and Adaptive Immunity to Salmonella: Importance of the Kupffer Cell Network.

A. Vazquez-Torres, B. A. Vallance, M. A. Bergman, B. B. Finlay, B. T. Cookson, J. Jones-Carson, and F. C. Fang (2004)
J. Immunol. 172, 6202-6208
 |  Abstract »  |  Full Text »  |  PDF »

Aerosolized Gamma Interferon (IFN-{gamma}) Induces Expression of the Genes Encoding the IFN-{gamma}-Inducible 10-Kilodalton Protein but Not Inducible Nitric Oxide Synthase in the Lung during Tuberculosis.

B. Raju, Y. Hoshino, K. Kuwabara, I. Belitskaya, S. Prabhakar, A. Canova, J. A. Gold, R. Condos, R. I. Pine, S. Brown, et al. (2004)
Infect. Immun. 72, 1275-1283
 |  Abstract »  |  Full Text »  |  PDF »

Posttranscriptional Inhibition of Gene Expression by Mycobacterium tuberculosis Offsets Transcriptional Synergism with IFN-{gamma} and Posttranscriptional Up-Regulation by IFN-{gamma}.

Y. Qiao, S. Prabhakar, A. Canova, Y. Hoshino, M. Weiden, and R. Pine (2004)
J. Immunol. 172, 2935-2943
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{gamma}: an overview of signals, mechanisms and functions.

K. Schroder, P. J. Hertzog, T. Ravasi, and D. A. Hume (2004)
J. Leukoc. Biol. 75, 163-189
 |  Abstract »  |  Full Text »  |  PDF »

Interferon Regulatory Factor-1 Mediates PPAR{gamma}-Induced Apoptosis in Vascular Smooth Muscle Cells.

Y. Lin, X. Zhu, F. L. Mclntee, H. Xiao, J. Zhang, M. Fu, and Y. E. Chen (2004)
Arterioscler Thromb Vasc Biol 24, 257-263
 |  Abstract »  |  Full Text »

Regulation of Inducible Nitric Oxide Synthase Expression by p300 and p50 Acetylation.

W.-G. Deng and K. K. Wu (2003)
J. Immunol. 171, 6581-6588
 |  Abstract »  |  Full Text »  |  PDF »

Role of Antiproliferative B Cell Translocation Gene-1 as an Apoptotic Sensitizer in Activation-Induced Cell Death of Brain Microglia.

H. Lee, S. Cha, M.-S. Lee, G. J. Cho, W. S. Choi, and K. Suk (2003)
J. Immunol. 171, 5802-5811
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{gamma}-Induced MHC Class II Expression: Transactivation of Class II Transactivator Promoter IV by IFN Regulatory Factor-1 is Regulated by Protein Kinase C-{alpha}.

M. Giroux, M. Schmidt, and A. Descoteaux (2003)
J. Immunol. 171, 4187-4194
 |  Abstract »  |  Full Text »  |  PDF »

Role for Nuclear Factor-{kappa}B and Signal Transducer and Activator of Transcription 1/Interferon Regulatory Factor-1 in Cytokine-Induced Endothelin-1 Release in Human Vascular Smooth Muscle Cells.

M. Woods, E. G. Wood, S. C. Bardswell, D. Bishop-Bailey, S. Barker, S. J. Wort, J. A. Mitchell, and T. D. Warner (2003)
Mol. Pharmacol. 64, 923-931
 |  Abstract »  |  Full Text »  |  PDF »

Nramp1 Functionality Increases Inducible Nitric Oxide Synthase Transcription Via Stimulation of IFN Regulatory Factor 1 Expression.

G. Fritsche, M. Dlaska, H. Barton, I. Theurl, K. Garimorth, and G. Weiss (2003)
J. Immunol. 171, 1994-1998
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of IFN-{gamma}-Mediated Inducible Nitric Oxide Synthase Induction by the Peroxisome Proliferator-Activated Receptor {gamma} Agonist, 15-Deoxy-{Delta}12,14-Prostaglandin J2, Involves Inhibition of the Upstream Janus Kinase/STAT1 Signaling Pathway.

C.-W. Chen, Y.-H. Chang, C.-J. Tsi, and W.-W. Lin (2003)
J. Immunol. 171, 979-988
 |  Abstract »  |  Full Text »  |  PDF »

Protection from autoimmune brain inflammation in mice lacking IFN-regulatory factor-1 is associated with Th2-type cytokines.

T. Buch, C. Uthoff-Hachenberg, and A. Waisman (2003)
Int. Immunol. 15, 855-859
 |  Abstract »  |  Full Text »  |  PDF »

STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation.

W. Xu, S. A. A. Comhair, S. Zheng, S. C. Chu, J. Marks-Konczalik, J. Moss, S. J. Haque, and S. C. Erzurum (2003)
Am J Physiol Lung Cell Mol Physiol 285, L137-L148
 |  Abstract »  |  Full Text »  |  PDF »

Inducible nitric oxide synthase expression inhibition by adenovirus E1A.

W. Cao, C. Bao, and C. J. Lowenstein (2003)
PNAS 100, 7773-7778
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Beta Interferon in Enhancing Inducible Nitric Oxide Synthase Production and Antimicrobial Activity of Burkholderiapseudomallei-Infected Macrophages.

P. Utaisincharoen, N. Anuntagool, K. Limposuwan, P. Chaisuriya, and S. Sirisinha (2003)
Infect. Immun. 71, 3053-3057
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Lipopolysaccharide Sensitivity by IFN Regulatory Factor-2.

N. Cuesta, C. A. Salkowski, K. E. Thomas, and S. N. Vogel (2003)
J. Immunol. 170, 5739-5747
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant Gamma Interferon Stimulates Signal Transduction and Gene Expression in Alveolar Macrophages In Vitro and in Tuberculosis Patients.

R. Condos, B. Raju, A. Canova, B.-Y. Zhao, M. Weiden, W. N. Rom, and R. Pine (2003)
Infect. Immun. 71, 2058-2064
 |  Abstract »  |  Full Text »

Role of the NF-{kappa}B Signaling Pathway and {kappa}B cis-Regulatory Elements on the IRF-1 and iNOS Promoter Regions in Mycobacterial Lipoarabinomannan Induction of Nitric Oxide.

K. R. Morris, R. D. Lutz, H.-S. Choi, T. Kamitani, K. Chmura, and E. D. Chan (2003)
Infect. Immun. 71, 1442-1452
 |  Abstract »  |  Full Text »  |  PDF »

Complex Formation of the Interferon (IFN) Consensus Sequence-binding Protein with IRF-1 Is Essential for Murine Macrophage IFN-gamma -induced iNOS Gene Expression.

H. Xiong, C. Zhu, H. Li, F. Chen, L. Mayer, K. Ozato, J. C. Unkeless, and S. E. Plevy (2003)
J. Biol. Chem. 278, 2271-2277
 |  Abstract »  |  Full Text »  |  PDF »

Identification of IFN Regulatory Factor-1 Binding Site in IL-12 p40 Gene Promoter.

S. Maruyama, K. Sumita, H. Shen, M. Kanoh, X. Xu, M. Sato, M. Matsumoto, H. Shinomiya, and Y. Asano (2003)
J. Immunol. 170, 997-1001
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Cyclooxygenase-2 Expression by Macrophages in Response to Double-Stranded RNA and Viral Infection.

S. A. Steer, J. M. Moran, L. B. Maggi Jr., R. M. L. Buller, H. Perlman, and J. A. Corbett (2003)
J. Immunol. 170, 1070-1076
 |  Abstract »  |  Full Text »  |  PDF »

Salicylate Suppresses Macrophage Nitric-oxide Synthase-2 and Cyclo-oxygenase-2 Expression by Inhibiting CCAAT/Enhancer-binding Protein-beta Binding via a Common Signaling Pathway.

K. Cieslik, Y. Zhu, and K. K. Wu (2002)
J. Biol. Chem. 277, 49304-49310
 |  Abstract »  |  Full Text »  |  PDF »

Virulence Criteria for Brucella abortus Strains as Determined by Interferon Regulatory Factor 1-Deficient Mice.

J. Ko, A. Gendron-Fitzpatrick, T. A. Ficht, and G. A. Splitter (2002)
Infect. Immun. 70, 7004-7012
 |  Abstract »  |  Full Text »  |  PDF »

Bacterial Colonization and the Expression of Inducible Nitric Oxide Synthase in Murine Wounds.

E. Mahoney, J. Reichner, L. Robinson Bostom, B. Mastrofrancesco, W. Henry, and J. Albina (2002)
Am. J. Pathol. 161, 2143-2152
 |  Abstract »  |  Full Text »  |  PDF »

Dysregulation of IFN-{gamma} Signaling Pathways in the Absence of TGF-{beta}1.

N. L. McCartney-Francis and S. M. Wahl (2002)
J. Immunol. 169, 5941-5947
 |  Abstract »  |  Full Text »  |  PDF »

Virulent Mycobacterium fortuitum Restricts NO Production by a Gamma Interferon-Activated J774 Cell Line and Phagosome-Lysosome Fusion.

T. R. M. da Silva, J. R. de Freitas, Q. C. Silva, C. P. Figueira, E. Roxo, S. C. Leao, L. A. R. de Freitas, and P. S. T. Veras (2002)
Infect. Immun. 70, 5628-5634
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Immunoproteasome Subunit Expression In Vivo Following Pathogenic Fungal Infection.

L. F. Barton, M. Cruz, R. Rangwala, G. S. Deepe Jr., and J. J. Monaco (2002)
J. Immunol. 169, 3046-3052
 |  Abstract »  |  Full Text »  |  PDF »

Complement Factor B Gene Regulation: Synergistic Effects of TNF-{alpha} and IFN-{gamma} in Macrophages.

Y. Huang, P. M. Krein, D. A. Muruve, and B. W. Winston (2002)
J. Immunol. 169, 2627-2635
 |  Abstract »  |  Full Text »  |  PDF »

Enhancement of the inducible NO synthase activation by retinoic acid is mimicked by RARalpha agonist in vivo.

C. Seguin-Devaux, Y. Devaux, V. Latger-Cannard, S. Grosjean, C. Rochette-Egly, F. Zannad, C. Meistelman, P.-M. Mertes, and D. Longrois (2002)
Am J Physiol Endocrinol Metab 283, E525-E535
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Transactivating Factor That Regulates Interferon-gamma -dependent Gene Expression.

J. Hu, Q. Meng, S. K. Roy, A. Raha, J. Hu, J. Zhang, K. Hashimoto, and D. V. Kalvakolanu (2002)
J. Biol. Chem. 277, 30253-30263
 |  Abstract »  |  Full Text »  |  PDF »

Developmental and Functional Defects of Thymic and Epidermal V{gamma}3 Cells in IL-15-Deficient and IFN Regulatory Factor-1-Deficient Mice.

A. De Creus, K. Van Beneden, F. Stevenaert, V. Debacker, J. Plum, and G. Leclercq (2002)
J. Immunol. 168, 6486-6493
 |  Abstract »  |  Full Text »  |  PDF »

Host Defense Responses to Infection by Mycobacterium tuberculosis. INDUCTION OF IRF-1 AND A SERINE PROTEASE INHIBITOR.

Y. Qiao, S. Prabhakar, E. M. Coccia, M. Weiden, A. Canova, E. Giacomini, and R. Pine (2002)
J. Biol. Chem. 277, 22377-22385
 |  Abstract »  |  Full Text »  |  PDF »

Transcription Factor IRF-1 in Kidney Transplants Mediates Resistance to Graft Necrosis during Rejection.

M. Afrouzian, V. Ramassar, J. Urmson, L.-F. Zhu, and P. F. Halloran (2002)
J. Am. Soc. Nephrol. 13, 1199-1209
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{alpha} as an immunotherapeutic protein.

D. L. Brassard, M. J. Grace, and R. W. Bordens (2002)
J. Leukoc. Biol. 71, 565-581
 |  Abstract »  |  Full Text »  |  PDF »

Transmembrane TNF Induces an Efficient Cell-Mediated Immunity and Resistance to Mycobacterium bovis Bacillus Calmette-Guerin Infection in the Absence of Secreted TNF and Lymphotoxin-{alpha}.

M. L. Olleros, R. Guler, N. Corazza, D. Vesin, H.-P. Eugster, G. Marchal, P. Chavarot, C. Mueller, and I. Garcia (2002)
J. Immunol. 168, 3394-3401
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Nuclear Gamma Interferon Gene Expression by Interleukin 12 (IL-12) and IL-2 Represents a Novel Form of Posttranscriptional Control.

D. L. Hodge, A. Martinez, J. G. Julias, L. S. Taylor, and H. A. Young (2002)
Mol. Cell. Biol. 22, 1742-1753
 |  Abstract »  |  Full Text »  |  PDF »

Pulmonary Inflammation Induced by Pseudomonas aeruginosa Lipopolysaccharide, Phospholipase C, and Exotoxin A: Role of Interferon Regulatory Factor 1.

C. W. Wieland, B. Siegmund, G. Senaldi, M. L. Vasil, C. A. Dinarello, and G. Fantuzzi (2002)
Infect. Immun. 70, 1352-1358
 |  Abstract »  |  Full Text »  |  PDF »

Susceptibility of IFN Regulatory Factor-1 and IFN Consensus Sequence Binding Protein-Deficient Mice to Brucellosis.

J. Ko, A. Gendron-Fitzpatrick, and G. A. Splitter (2002)
J. Immunol. 168, 2433-2440
 |  Abstract »  |  Full Text »  |  PDF »

Viral IFN-Regulatory Factors Inhibit Activation-Induced Cell Death Via Two Positive Regulatory IFN-Regulatory Factor 1-Dependent Domains in the CD95 Ligand Promoter.

S. Kirchhoff, T. Sebens, S. Baumann, A. Krueger, R. Zawatzky, M. Li-Weber, E. Meinl, F. Neipel, B. Fleckenstein, and P. H. Krammer (2002)
J. Immunol. 168, 1226-1234
 |  Abstract »  |  Full Text »  |  PDF »

Role of Interferon Regulatory Factor-1 in Double-stranded RNA-induced iNOS Expression by Mouse Islets.

L. A. Blair, L. B. Maggi Jr., A. L. Scarim, and J. A. Corbett (2002)
J. Biol. Chem. 277, 359-365
 |  Abstract »  |  Full Text »

Induction of Gamma Interferon and Nitric Oxide by Truncated Pneumolysin That Lacks Pore-Forming Activity.

H. Baba, I. Kawamura, C. Kohda, T. Nomura, Y. Ito, T. Kimoto, I. Watanabe, S. Ichiyama, and M. Mitsuyama (2002)
Infect. Immun. 70, 107-113
 |  Abstract »  |  Full Text »  |  PDF »

Immunity, Inflammation, and Remodeling in the Airway Epithelial Barrier: Epithelial-Viral-Allergic Paradigm.

M. J. Holtzman, J. D. Morton, L. P. Shornick, J. W. Tyner, M. P. O'Sullivan, A. Antao, M. Lo, M. Castro, and M. J. Walter (2002)
Physiol Rev 82, 19-46
 |  Abstract »  |  Full Text »  |  PDF »

Molecular mechanisms of iNOS induction by IL-1beta and IFN-gamma in rat aortic smooth muscle cells.

X. Teng, H. Zhang, C. Snead, and J. D. Catravas (2002)
Am J Physiol Cell Physiol 282, C144-C152
 |  Abstract »  |  Full Text »  |  PDF »

Lipopolysaccharide-induced Expression of Interferon-beta Mediates the Timing of Inducible Nitric-oxide Synthase Induction in RAW 264.7 Macrophages.

A. T. Jacobs and L. J. Ignarro (2001)
J. Biol. Chem. 276, 47950-47957
 |  Abstract »  |  Full Text »  |  PDF »

Specific Inhibition of Interferon Signal Transduction Pathways by Adenoviral Infection.

T. D. Joseph and D. C. Look (2001)
J. Biol. Chem. 276, 47136-47142
 |  Abstract »  |  Full Text »  |  PDF »

Trypanocidal Drug Benznidazole Impairs Lipopolysaccharide Induction of Macrophage Nitric Oxide Synthase Gene Transcription Through Inhibition of NF-{kappa}B Activation.

E. Piaggio, J. Sanceau, S. Revelli, O. Bottasso, J. Wietzerbin, and E. Serra (2001)
J. Immunol. 167, 3422-3426
 |  Abstract »  |  Full Text »  |  PDF »

Cyclooxygenase-2 downregulates inducible nitric oxide synthase in rat intestinal epithelial cells.

O. Kobayashi, H. Miwa, S. Watanabe, M. Tsujii, R. N. Dubois, and N. Sato (2001)
Am J Physiol Gastrointest Liver Physiol 281, G688-G696
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the actin cytoskeleton regulates cytokine-induced iNOS expression.

C. Zeng and A. R. Morrison (2001)
Am J Physiol Cell Physiol 281, C932-C940
 |  Abstract »  |  Full Text »  |  PDF »

Down-Regulation of IL-12 p40 Gene in Plasmodium berghei-Infected Mice.

X. Xu, K. Sumita, C. Feng, X. Xiong, H. Shen, S. Maruyama, M. Kanoh, and Y. Asano (2001)
J. Immunol. 167, 235-241
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide synthase 2 through an autocrine loop via respiratory epithelial cell-derived mediator.

K. Uetani, M. J. Thomassen, and S. C. Erzurum (2001)
Am J Physiol Lung Cell Mol Physiol 280, L1179-L1188
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TNF-{{alpha}} Controls Intracellular Mycobacterial Growth by Both Inducible Nitric Oxide Synthase-Dependent and Inducible Nitric Oxide Synthase-Independent Pathways.

L.-G. Bekker, S. Freeman, P. J. Murray, B. Ryffel, and G. Kaplan (2001)
J. Immunol. 166, 6728-6734
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Intersection of Interferon and Hypoxia Signal Transduction Pathways in Nitric Oxide-induced Tumor Apoptosis.

D. S. Tendler, C. Bao, T. Wang, E. L. Huang, E. A. Ratovitski, D. A. Pardoll, and C. J. Lowenstein (2001)
Cancer Res. 61, 3682-3688
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Engineering of Macrophages to Produce IFN-{{gamma}} in Response to Hypoxia.

L. Carta, S. Pastorino, G. Melillo, M. C. Bosco, S. Massazza, and L. Varesio (2001)
J. Immunol. 166, 5374-5380
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Induction of Inducible Nitric Oxide Synthase-NO{middle dot} by Lipoarabinomannan of Mycobacterium tuberculosis Is Mediated by MEK1-ERK, MKK7-JNK, and NF-{kappa}B Signaling Pathways.

E. D. Chan, K. R. Morris, J. T. Belisle, P. Hill, L. K. Remigio, P. J. Brennan, and D. W. H. Riches (2001)
Infect. Immun. 69, 2001-2010
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Requirement for STAT1 in LPS-induced gene expression in macrophages.

Y. Ohmori and T. A. Hamilton (2001)
J. Leukoc. Biol. 69, 598-604
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IFN-{{gamma}}/TNF-{{alpha}} Synergism as the Final Effector in Autoimmune Diabetes: A Key Role for STAT1/IFN Regulatory Factor-1 Pathway in Pancreatic {{beta}} Cell Death.

K. Suk, S. Kim, Y.-H. Kim, K.-A. Kim, I. Chang, H. Yagita, M. Shong, and M.-S. Lee (2001)
J. Immunol. 166, 4481-4489
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Growth Suppression of the Hepatocellular Carcinoma Cell Line Hepa1-6 by an Activatable Interferon Regulatory Factor-1 in Mice.

A. Kröger, D. Ortmann, T. U. Krohne, L. Mohr, H. E. Blum, H. Hauser, and M. Geissler (2001)
Cancer Res. 61, 2609-2617
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IFN-{gamma} + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38mapk in a mouse macrophage cell line.

E. D. Chan and D. W. H. Riches (2001)
Am J Physiol Cell Physiol 280, C441-C450
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Role of Nitric Oxide Synthase Type 2 in Acute Infection with Murine Cytomegalovirus.

S. Noda, K. Tanaka, S.-a. Sawamura, M. Sasaki, T. Matsumoto, K. Mikami, Y. Aiba, H. Hasegawa, N. Kawabe, and Y. Koga (2001)
J. Immunol. 166, 3533-3541
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Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production.

R. Rutschman, R. Lang, M. Hesse, J. N. Ihle, T. A. Wynn, and P. J. Murray (2001)
J. Immunol. 166, 2173-2177
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Expression of the Nitric Oxide Synthase 2 Gene Is Not Essential for Early Control of Mycobacterium tuberculosis in the Murine Lung.

A. M. Cooper, J. E. Pearl, J. V. Brooks, S. Ehlers, and I. M. Orme (2000)
Infect. Immun. 68, 6879-6882
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Retinoic acid and host-pathogen interactions: effects on inducible nitric oxide synthase in vivo.

Y. Devaux, S. Grosjean, C. Seguin, C. David, B. Dousset, F. Zannad, C. Meistelman, N. De Talance, P.-M. Mertes, and D. Ungureanu-Longrois (2000)
Am J Physiol Endocrinol Metab 279, E1045-E1053
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Characterization of a Novel Human Herpesvirus 8-Encoded Protein, vIRF-3, That Shows Homology to Viral and Cellular Interferon Regulatory Factors.

B. Lubyova and P. M. Pitha (2000)
J. Virol. 74, 8194-8201
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Deficiency in the Transcription Factor Interferon Regulatory Factor (Irf)-2 Leads to Severely Compromised Development of Natural Killer and T Helper Type 1 Cells.

M. Lohoff, G. S. Duncan, D. Ferrick, H.-W. Mittrucker, S. Bischof, S. Prechtl, M. Rollinghoff, E. Schmitt, A. Pahl, and T. W. Mak (2000)
J. Exp. Med. 192, 325-336
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Central Role of Double-Stranded RNA-Activated Protein Kinase in Microbial Induction of Nitric Oxide Synthase.

K. Uetani, S. D. Der, M. Zamanian-Daryoush, C. de la Motte, B. Y. Lieberman, B. R. G. Williams, and S. C. Erzurum (2000)
J. Immunol. 165, 988-996
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IFN-{gamma} and IL-4 differently regulate inducible NO synthase gene expression through IRF-1 modulation.

E. M. Coccia, E. Stellacci, G. Marziali, G. Weiss, and A. Battistini (2000)
Int. Immunol. 12, 977-985
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Interferon Regulatory Factor (Irf)-1 and Irf-2 Regulate Interferon {gamma}-Dependent Cyclooxygenase 2 Expression.

J. C. G. Blanco, C. Contursi, C. A. Salkowski, D. L. DeWitt, K. Ozato, and S. N. Vogel (2000)
J. Exp. Med. 191, 2131-2144
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Molecular Mechanisms of Increased Nitric Oxide (NO) in Asthma: Evidence for Transcriptional and Post-Translational Regulation of NO Synthesis.

F. H. Guo, S. A. A. Comhair, S. Zheng, R. A. Dweik, N. T. Eissa, M. J. Thomassen, W. Calhoun, and S. C. Erzurum (2000)
J. Immunol. 164, 5970-5980
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The Cytotoxic Enterotoxin of Aeromonas hydrophila Induces Proinflammatory Cytokine Production and Activates Arachidonic Acid Metabolism in Macrophages.

A. K. Chopra, X.-J. Xu, D. Ribardo, M. Gonzalez, K. Kuhl, J. W. Peterson, and C. W. Houston (2000)
Infect. Immun. 68, 2808-2818
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CCAAT/Enhancer-binding Protein-beta Regulates Interferon-induced Transcription through a Novel Element.

S. K. Roy, S. J. Wachira, X. Weihua, J. Hu, and D. V. Kalvakolanu (2000)
J. Biol. Chem. 275, 12626-12632
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Interferon-{gamma} Induces AT2 Receptor Expression in Fibroblasts by Jak/STAT Pathway and Interferon Regulatory Factor-1.

M. Horiuchi, W. Hayashida, M. Akishita, S. Yamada, J. Y. A. Lehtonen, K. Tamura, L. Daviet, Y. E. Chen, M. Hamai, T.-X. Cui, et al. (2000)
Circ. Res. 86, 233-240
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Inflammation influences vascular remodeling through AT2 receptor expression and signaling.

M. AKISHITA, M. HORIUCHI, H. YAMADA, L. ZHANG, G. SHIRAKAMI, K. TAMURA, Y. OUCHI, and V. J. DZAU (2000)
Physiol Genomics 2, 13-20
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Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex.

K. Ohashi, V. Burkart, S. Flohe, and H. Kolb (2000)
J. Immunol. 164, 558-561
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Can Murine Uterine Natural Killer Cells Give Insights Into the Pathogenesis of Preeclampsia?.

B. A. Croy, A. A. Ashkar, K. Minhas, and J. D. Greenwood (2000)
Reproductive Sciences 7, 12-20
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