Science 25 February 1994: Vol. 263. no. 5150, pp. 1128 - 1130 DOI: 10.1126/science.8108730

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Articles

Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice.

A. A. Tomilov, V. Bicocca, R. A. Schoenfeld, M. Giorgio, E. Migliaccio, J. J. Ramsey, K. Hagopian, P. G. Pelicci, and G. A. Cortopassi (2010)
J. Biol. Chem. 285, 1153-1165
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondrial Telomerase Reverse Transcriptase Binds to and Protects Mitochondrial DNA and Function From Damage.

J. Haendeler, S. Drose, N. Buchner, S. Jakob, J. Altschmied, C. Goy, I. Spyridopoulos, A. M. Zeiher, U. Brandt, and S. Dimmeler (2009)
Arterioscler Thromb Vasc Biol 29, 929-935
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Glucose-6-phosphate Dehydrogenase Extends the Life Span of Drosophila melanogaster.

S. K. Legan, I. Rebrin, R. J. Mockett, S. N. Radyuk, V. I. Klichko, R. S. Sohal, and W. C. Orr (2008)
J. Biol. Chem. 283, 32492-32499
 |  Abstract »  |  Full Text »  |  PDF »

Protein Repair L-Isoaspartyl Methyltransferase1 Is Involved in Both Seed Longevity and Germination Vigor in Arabidopsis.

L. Oge, G. Bourdais, J. Bove, B. Collet, B. Godin, F. Granier, J.-P. Boutin, D. Job, M. Jullien, and P. Grappin (2008)
PLANT CELL 20, 3022-3037
 |  Abstract »  |  Full Text »  |  PDF »

How to Live Long and Prosper: Autophagy, Mitochondria, and Aging.

W.-L. Yen and D. J. Klionsky (2008)
Physiology 23, 248-262
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative Stress Stimulates Testicular Orphan Receptor 4 through Forkhead Transcription Factor Forkhead Box O3a.

G. Li, Y.-F. Lee, S. Liu, Y. Cai, S. Xie, N.-C. Liu, B.-Y. Bao, Z. Chen, and C. Chang (2008)
Endocrinology 149, 3490-3499
 |  Abstract »  |  Full Text »  |  PDF »

Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance.

M.-C. Gomez-Cabrera, E. Domenech, M. Romagnoli, A. Arduini, C. Borras, F. V Pallardo, J. Sastre, and J. Vina (2008)
Am. J. Clinical Nutrition 87, 142-149
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Redox-Signaling Is Essential for Apoptosis Inhibition in Endothelial Cells Important Role for Nuclear Thioredoxin-1.

P. Schroeder, R. Popp, B. Wiegand, J. Altschmied, and J. Haendeler (2007)
Arterioscler Thromb Vasc Biol 27, 2325-2331
 |  Abstract »  |  Full Text »  |  PDF »

Octopamine-Mediated Neuronal Plasticity in Honeybees: Implications for Olfactory Dysfunction in Humans.

T. Farooqui (2007)
Neuroscientist 13, 304-322
 |  Abstract »  |  PDF »

Sir2p-dependent protein segregation gives rise to a superior reactive oxygen species management in the progeny of Saccharomyces cerevisiae.

N. Erjavec and T. Nystrom (2007)
PNAS 104, 10877-10881
 |  Abstract »  |  Full Text »  |  PDF »

Cardiac mitochondrial bioenergetics, oxidative stress, and aging.

S. Judge and C. Leeuwenburgh (2007)
Am J Physiol Cell Physiol 292, C1983-C1992
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative Stress, Mitochondrial DNA Mutation, and Apoptosis in Aging.

H.-C. Lee and Y.-H. Wei (2007)
Experimental Biology and Medicine 232, 592-606
 |  Abstract »  |  Full Text »  |  PDF »

Reactive oxygen species detoxification by catalase is a major determinant of fecundity in the mosquito Anopheles gambiae.

R. J. DeJong, L. M. Miller, A. Molina-Cruz, L. Gupta, S. Kumar, and C. Barillas-Mury (2007)
PNAS 104, 2121-2126
 |  Abstract »  |  Full Text »  |  PDF »

The mitochondrial energy transduction system and the aging process.

A. Navarro and A. Boveris (2007)
Am J Physiol Cell Physiol 292, C670-C686
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: A Drosophila model for age-associated changes in sleep:wake cycles.

K. Koh, J. M. Evans, J. C. Hendricks, and A. Sehgal (2006)
PNAS 103, 13843-13847
 |  Abstract »  |  Full Text »  |  PDF »

daf-16 Protects the Nematode Caenorhabditis elegans During Food Deprivation..

S. T. Henderson, M. Bonafe, and T. E. Johnson (2006)
J. Gerontol. A Biol. Sci. Med. Sci. 61, 444-460
 |  Abstract »  |  Full Text »  |  PDF »

Reactive Oxygen Species-Mediated Mitochondria-to-Nucleus Signaling: A Key to Aging and Radical-Caused Diseases.

P. Storz (2006)
Sci. STKE 2006, re3
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative Damage and Aging: Spotlight on Mitochondria..

N. J. Linford, S. E. Schriner, and P. S. Rabinovitch (2006)
Cancer Res. 66, 2497-2499
 |  Abstract »  |  Full Text »  |  PDF »

Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency.

G. López-Lluch, N. Hunt, B. Jones, M. Zhu, H. Jamieson, S. Hilmer, M. V. Cascajo, J. Allard, D. K. Ingram, P. Navas, et al. (2006)
PNAS 103, 1768-1773
 |  Abstract »  |  Full Text »  |  PDF »

Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice.

C.-C. Hsieh and J. Papaconstantinou (2006)
FASEB J 20, 259-268
 |  Abstract »  |  Full Text »  |  PDF »

Reactive oxygen species and redox-regulation of skeletal muscle adaptations to exercise.

M. J Jackson (2005)
Phil Trans R Soc B 360, 2285-2291
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative stress and ageing: is ageing a cysteine deficiency syndrome?.

W. Droge (2005)
Phil Trans R Soc B 360, 2355-2372
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production.

A. Trifunovic, A. Hansson, A. Wredenberg, A. T. Rovio, E. Dufour, I. Khvorostov, J. N. Spelbrink, R. Wibom, H. T. Jacobs, and N.-G. Larsson (2005)
PNAS 102, 17993-17998
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondrial Genetics of Aging: Intergenomic Conflict Resolution.

D. M. Rand (2005)
Sci. Aging Knowl. Environ. 2005, re5
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative Aging and Insulin Receptor Signaling.

W. Droge (2005)
J. Gerontol. A Biol. Sci. Med. Sci. 60, 1378-1385
 |  Abstract »  |  Full Text »  |  PDF »

Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress.

A. B. Salmon, S. Murakami, A. Bartke, J. Kopchick, K. Yasumura, and R. A. Miller (2005)
Am J Physiol Endocrinol Metab 289, E23-E29
 |  Abstract »  |  Full Text »  |  PDF »

Reactive Oxygen Species and Aging: Evolving Questions.

L. L. Dugan and K. L. Quick (2005)
Sci. Aging Knowl. Environ. 2005, pe20
 |  Abstract »  |  Full Text »

Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria.

S. E. Schriner, N. J. Linford, G. M. Martin, P. Treuting, C. E. Ogburn, M. Emond, P. E. Coskun, W. Ladiges, N. Wolf, H. Van Remmen, et al. (2005)
Science 308, 1909-1911
 |  Abstract »  |  Full Text »  |  PDF »

Why Females Live Longer Than Males: Control of Longevity by Sex Hormones.

J. Vina, C. Borras, J. Gambini, J. Sastre, and F. V. Pallardo (2005)
Sci. Aging Knowl. Environ. 2005, pe17
 |  Abstract »  |  Full Text »

Manganese Superoxide Dismutase Protects the Proliferative Capacity of Confluent Normal Human Fibroblasts.

E. H. Sarsour, M. Agarwal, T. K. Pandita, L. W. Oberley, and P. C. Goswami (2005)
J. Biol. Chem. 280, 18033-18041
 |  Abstract »  |  Full Text »  |  PDF »

MnSOD and Catalase Transgenes Demonstrate That Protection of Islets From Oxidative Stress Does Not Alter Cytokine Toxicity.

H. Chen, X. Li, and P. N. Epstein (2005)
Diabetes 54, 1437-1446
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondria, Reactive Oxygen Species, and Aging.

N. J. Linford, S. E. Schriner, and P. S. Rabinovitch (2005)
Am. Assoc. Cancer Res. Educ. Book 2005, 264-266
 |  Full Text »  |  PDF »

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands.

S. J. Broughton, M. D. W. Piper, T. Ikeya, T. M. Bass, J. Jacobson, Y. Driege, P. Martinez, E. Hafen, D. J. Withers, S. J. Leevers, et al. (2005)
PNAS 102, 3105-3110
 |  Abstract »  |  Full Text »  |  PDF »

Longevity and Metabolism in Drosophila melanogaster: Genetic Correlations Between Life Span and Age-Specific Metabolic Rate in Populations Artificially Selected for Long Life.

A. A. Khazaeli, W. Van Voorhies, and J. W. Curtsinger (2005)
Genetics 169, 231-242
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative Trait Loci Affecting Life Span in Replicated Populations of Drosophila melanogaster. I. Composite Interval Mapping.

S. N. Forbes, R. K. Valenzuela, P. Keim, and P. M. Service (2004)
Genetics 168, 301-311
 |  Abstract »  |  Full Text »  |  PDF »

An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster.

J. H. Bauer, S. Goupil, G. B. Garber, and S. L. Helfand (2004)
PNAS 101, 12980-12985
 |  Abstract »  |  Full Text »  |  PDF »

Multiple-stress analysis for isolation of Drosophila longevity genes.

H.-D. Wang, P. Kazemi-Esfarjani, and S. Benzer (2004)
PNAS 101, 12610-12615
 |  Abstract »  |  Full Text »  |  PDF »

Antioxidant Effects of Statins via S-Nitrosylation and Activation of Thioredoxin in Endothelial Cells: A Novel Vasculoprotective Function of Statins.

J. Haendeler, J. Hoffmann, A. M. Zeiher, and S. Dimmeler (2004)
Circulation 110, 856-861
 |  Abstract »  |  Full Text »  |  PDF »

Ticking Fast or Ticking Slow, Through Shc Must You Go?.

F. M. Martin and J. S. Friedman (2004)
Sci. Aging Knowl. Environ. 2004, pe32
 |  Abstract »  |  Full Text »

Sex-Specific Effects of Interventions That Extend Fly Life Span.

J. M. S. Burger and D. E. L. Promislow (2004)
Sci. Aging Knowl. Environ. 2004, pe30
 |  Abstract »  |  Full Text »

From the Cover: Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl.

D. W. Walker and S. Benzer (2004)
PNAS 101, 10290-10295
 |  Abstract »  |  Full Text »  |  PDF »

S.W.A.T.--SOD Weapons and Tactics.

J. N. Sampayo and G. J. Lithgow (2004)
Sci. Aging Knowl. Environ. 2004, pe27
 |  Abstract »  |  Full Text »

Aging: The Reality: Demography of Human Supercentenarians.

L. S. Coles (2004)
J. Gerontol. A Biol. Sci. Med. Sci. 59, B579-B586
 |  Abstract »  |  Full Text »  |  PDF »

Antioxidants Inhibit Nuclear Export of Telomerase Reverse Transcriptase and Delay Replicative Senescence of Endothelial Cells.

J. Haendeler, J. Hoffmann, J. F. Diehl, M. Vasa, I. Spyridopoulos, A. M. Zeiher, and S. Dimmeler (2004)
Circ. Res. 94, 768-775
 |  Abstract »  |  Full Text »  |  PDF »

Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan.

J. D. Parker, K. M. Parker, B. H. Sohal, R. S. Sohal, and L. Keller (2004)
PNAS 101, 3486-3489
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional regulation of the Drosophila catalase gene by the DRE/DREF system.

S. Y. Park, Y.-S. Kim, D.-J. Yang, and M.-A. Yoo (2004)
Nucleic Acids Res. 32, 1318-1324
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of L-Isoaspartate O-Methyltransferase in Escherichia coli Increases Heat Shock Survival by a Mechanism Independent of Methyltransferase Activity.

J. Kindrachuk, J. Parent, G. F. Davies, M. Dinsmore, S. Attah-Poku, and S. Napper (2003)
J. Biol. Chem. 278, 50880-50886
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondrial formation of reactive oxygen species.

J. F Turrens (2003)
J. Physiol. 552, 335-344
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Biology of Aging.

S. Kim (2003)
Arch Surg 138, 1051-1054
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of c-Myc Oncoprotein Limits the Growth of Human Melanoma Cells by Inducing Cellular Crisis.

A. Biroccio, S. Amodei, A. Antonelli, B. Benassi, and G. Zupi (2003)
J. Biol. Chem. 278, 35693-35701
 |  Abstract »  |  Full Text »  |  PDF »

Calorie restriction and aging: review of the literature and implications for studies in humans.

L. K Heilbronn and E. Ravussin (2003)
Am. J. Clinical Nutrition 78, 361-369
 |  Abstract »  |  Full Text »  |  PDF »

Effect of DNA Repair on Aging of Transgenic Drosophila melanogaster: I. mei-41 Locus.

S. Symphorien and R. C. Woodruff (2003)
J. Gerontol. A Biol. Sci. Med. Sci. 58, B782-787
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Overexpression of Copper-Zinc and Manganese Superoxide Dismutases, Catalase, and Thioredoxin Reductase Genes on Longevity in Drosophila melanogaster.

W. C. Orr, R. J. Mockett, J. J. Benes, and R. S. Sohal (2003)
J. Biol. Chem. 278, 26418-26422
 |  Abstract »  |  Full Text »  |  PDF »

A homologue of elongation factor 1{gamma} regulates methionine sulfoxide reductase A gene expression in Saccharomyces cerevisiae.

I. Hanbauer, E. S. Boja, and J. Moskovitz (2003)
PNAS 100, 8199-8204
 |  Abstract »  |  Full Text »  |  PDF »

RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress.

K. Kirby, J. Hu, A. J. Hilliker, and J. P. Phillips (2002)
PNAS 99, 16162-16167
 |  Abstract »  |  Full Text »  |  PDF »

Endothelial cells maintain a reduced redox environment even as mitochondrial function declines.

R. Carlisle, C. A. Rhoads, T. Y. Aw, and L. Harrison (2002)
Am J Physiol Cell Physiol 283, C1675-C1686
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression and Localization of Mn and Fe Superoxide Dismutases in the Heterocystous Cyanobacterium Anabaena sp. Strain PCC 7120.

T. Li, X. Huang, R. Zhou, Y. Liu, B. Li, C. Nomura, and J. Zhao (2002)
J. Bacteriol. 184, 5096-5103
 |  Abstract »  |  Full Text »  |  PDF »

Induced Overexpression of Mitochondrial Mn-Superoxide Dismutase Extends the Life Span of Adult Drosophila melanogaster.

J. Sun, D. Folk, T. J. Bradley, and J. Tower (2002)
Genetics 161, 661-672
 |  Abstract »  |  Full Text »  |  PDF »

Genes, Culture, and Aging Flies--What the Lab Can and Cannot Tell Us About Natural Genetic Variation for Senescence.

C. C. Spencer and D. E. L. Promislow (2002)
Sci. Aging Knowl. Environ. 2002, pe6-6
 |  Abstract »  |  Full Text »

Both lipid and protein intakes stimulate increased generation of reactive oxygen species by polymorphonuclear leukocytes and mononuclear cells.

P. Mohanty, H. Ghanim, W. Hamouda, A. Aljada, R. Garg, and P. Dandona (2002)
Am. J. Clinical Nutrition 75, 767-772
 |  Abstract »  |  Full Text »  |  PDF »

Redundancy, phylogeny and differential expression of Histoplasma capsulatum catalases.

C. H. Johnson, M. G. Klotz, J. L. York, V. Kruft, and J. E. McEwen (2002)
Microbiology 148, 1129-1142
 |  Abstract »  |  Full Text »  |  PDF »

High-quality life extension by the enzyme peptide methionine sulfoxide reductase.

H. Ruan, X. D. Tang, M.-L. Chen, M.-L. A. Joiner, G. Sun, N. Brot, H. Weissbach, S. H. Heinemann, L. Iverson, C.-F. Wu, et al. (2002)
PNAS 99, 2748-2753
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Copper Zinc Superoxide Dismutase Suppresses Human Glioma Cell Growth.

Y. Zhang, W. Zhao, H. J. Zhang, F. E. Domann, and L. W. Oberley (2002)
Cancer Res. 62, 1205-1212
 |  Abstract »  |  Full Text »  |  PDF »

Erythromycin Slows Aging of Saccharomyces cerevisiae.

M. A. Holbrook and J. R. Menninger (2002)
J. Gerontol. A Biol. Sci. Med. Sci. 57, B29-36
 |  Abstract »  |  Full Text »  |  PDF »

Free Radicals in the Physiological Control of Cell Function.

W. Droge (2002)
Physiol Rev 82, 47-95
 |  Abstract »  |  Full Text »  |  PDF »

Aging Research Grows Up.

M. Leslie (2001)
Sci. Aging Knowl. Environ. 2001, oa1-1
 |  Abstract »  |  Full Text »  |  PDF »

The Two Faces of Oxygen.

R. Tuma (2001)
Sci. Aging Knowl. Environ. 2001, oa5-5
 |  Abstract »  |  Full Text »  |  PDF »

Mutant Models of Prolonged Life Span.

J. F. Mahler (2001)
Toxicol Pathol 29, 673-676
 |  Abstract »  |  PDF »

Direct Selection for Paraquat Resistance in Drosophila Results in a Different Extended Longevity Phenotype.

J. Vettraino, S. Buck, and R. Arking (2001)
J. Gerontol. A Biol. Sci. Med. Sci. 56, B415-425
 |  Abstract »  |  Full Text »  |  PDF »

Respiration Capacity of the Fermenting Bacterium Lactococcus lactis and Its Positive Effects on Growth and Survival.

P. Duwat, S. Sourice, B. Cesselin, G. Lamberet, K. Vido, P. Gaudu, Y. Le Loir, F. Violet, P. Loubiere, and A. Gruss (2001)
J. Bacteriol. 183, 4509-4516
 |  Abstract »  |  Full Text »  |  PDF »

Genes That Prolong Life: Relationships of Growth Hormone and Growth to Aging and Life Span.

A. Bartke, K. Coschigano, J. Kopchick, V. Chandrashekar, J. Mattison, B. Kinney, and S. Hauck (2001)
J. Gerontol. A Biol. Sci. Med. Sci. 56, B340-349
 |  Abstract »  |  Full Text »  |  PDF »

Heat Shock Protein Accumulation Is Upregulated in a Long-Lived Mutant of Caenorhabditis elegans.

G. A. Walker, T. M. White, G. McColl, N. L. Jenkins, S. Babich, E. P. M. Candido, T. E. Johnson, and G. J. Lithgow (2001)
J. Gerontol. A Biol. Sci. Med. Sci. 56, B281-287
 |  Abstract »  |  Full Text »  |  PDF »

Hormesis: a quest for virtuality?.

O Toussaint, J Remacle, J-F Dierick, T Pascal, C Frippiat, J P Magalhaes, and F Chainaux (2001)
Human and Experimental Toxicology 20, 311-314
 |  PDF »

Free Radical Defenses in the Liver and Kidney of Human Growth Hormone Transgenic Mice: Possible Mechanisms of Early Mortality.

S. J. Hauck and A. Bartke (2001)
J. Gerontol. A Biol. Sci. Med. Sci. 56, 153B-162
 |  Abstract »  |  Full Text »

Caloric Restriction Mimetics: Metabolic Interventions.

R. Weindruch, K. P. Keenan, J. M. Carney, G. Fernandes, R. J. Feuers, R. A. Floyd, J. B. Halter, J. J. Ramsey, A. Richardson, G. S. Roth, et al. (2001)
J. Gerontol. A Biol. Sci. Med. Sci. 56, 20-33
 |  Abstract »  |  Full Text »  |  PDF »

Cell Senescence and Its Implications for Nephrology.

A. MELK and P. F. HALLORAN (2001)
J. Am. Soc. Nephrol. 12, 385-393
 |  Full Text »

Reversible Effects of Long-Term Caloric Restriction on Protein Oxidative Damage.

M. J. Forster, B. H. Sohal, and R. S. Sohal (2000)
J. Gerontol. A Biol. Sci. Med. Sci. 55, 522B-529
 |  Abstract »  |  Full Text »

Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics.

S. Melov, J. Ravenscroft, S. Malik, M. S. Gill, D. W. Walker, P. E. Clayton, D. C. Wallace, B. Malfroy, S. R. Doctrow, and G. J. Lithgow (2000)
Science 289, 1567-1569
 |  Abstract »  |  Full Text »

Sip2p and its partner Snf1p kinase affect aging in S. cerevisiae.

K. Ashrafi, S. S. Lin, J. K. Manchester, and J. I. Gordon (2000)
Genes & Dev. 14, 1872-1885
 |  Abstract »  |  Full Text »

Quantitative Trait Loci for Life Span in Drosophila melanogaster: Interactions With Genetic Background and Larval Density.

J. Leips and T. F. C. Mackay (2000)
Genetics 155, 1773-1788
 |  Abstract »  |  Full Text »

Cloning and Expression of the Bioluminescent Photoprotein Pholasin from the Bivalve Mollusc Pholas dactylus.

S. L. Dunstan, G. B. Sala-Newby, A. B. Fajardo, K. M. Taylor, and A. K. Campbell (2000)
J. Biol. Chem. 275, 9403-9409
 |  Abstract »  |  Full Text »  |  PDF »

Genotype-Environment Interaction for Quantitative Trait Loci Affecting Life Span in Drosophila melanogaster.

C. Vieira, E. G. Pasyukova, Z.-B. Zeng, J. B. Hackett, R. F. Lyman, and T. F. C. Mackay (2000)
Genetics 154, 213-227
 |  Abstract »  |  Full Text »

Aging: Is Oxidative Stress a Marker or Is It Causal?.

N. K. Fukagawa (1999)
Experimental Biology and Medicine 222, 293-298
 |  Abstract »  |  Full Text »

Overexpression of glutathione reductase extends survival in transgenic Drosophila melanogaster under hyperoxia but not normoxia.

R. J. MOCKETT, R. S. SOHAL, and W. C. ORR (1999)
FASEB J 13, 1733-1742
 |  Abstract »  |  Full Text »

Oxidative Stress Defense and Deterioration of Growth-arrested Escherichia coli Cells.

S. Dukan and T. Nystrom (1999)
J. Biol. Chem. 274, 26027-26032
 |  Abstract »  |  Full Text »  |  PDF »

Gene Expression Profile of Aging and Its Retardation by Caloric Restriction.

C. Lee, R. G. Klopp, R. Weindruch, and T. A. Prolla (1999)
Science 285, 1390-1393
 |  Abstract »  |  Full Text »

The Activation of the Rat Copper/Zinc Superoxide Dismutase Gene by Hydrogen Peroxide through the Hydrogen Peroxide-responsive Element and by Paraquat and Heat Shock through the Same Heat Shock Element.

H. Y. Yoo, M. S. Chang, and H. M. Rho (1999)
J. Biol. Chem. 274, 23887-23892
 |  Abstract »  |  Full Text »  |  PDF »

The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans.

Y. HONDA and S. HONDA (1999)
FASEB J 13, 1385-1393
 |  Abstract »  |  Full Text »

Influence of Sex, Smoking and Age on Human hprt Mutation Frequencies and Spectra.

J. Curry, L. Karnaoukhova, G. C. Guenette, and B. W. Glickman (1999)
Genetics 152, 1065-1077
 |  Abstract »  |  Full Text »

Chimeras of human extracellular and intracellular superoxide dismutases. Analysis of structure and function of the individual domains.

P. Stenlund and L. A.E. Tibell (1999)
Protein Eng. Des. Sel. 12, 319-325
 |  Abstract »  |  Full Text »  |  PDF »

FLP Recombinase-Mediated Induction of Cu/Zn-Superoxide Dismutase Transgene Expression Can Extend the Life Span of Adult Drosophila melanogaster Flies.

J. Sun and J. Tower (1999)
Mol. Cell. Biol. 19, 216-228
 |  Abstract »  |  Full Text »  |  PDF »

The Human Copper-Zinc Superoxide Dismutase Gene (SOD1) Proximal Promoter Is Regulated by Sp1, Egr-1, and WT1 via Non-canonical Binding Sites.

E. Minc, P. de Coppet, P. Masson, L. Thiery, S. Dutertre, M. Amor-Gueret, and C. Jaulin (1999)
J. Biol. Chem. 274, 503-509
 |  Abstract »  |  Full Text »  |  PDF »

Extended Life-Span and Stress Resistance in the Drosophila Mutant methuselah.

Y. Lin, L. Seroude, and S. Benzer (1998)
Science 282, 943-946
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Molecular Cloning and Expression Analysis of the Rhodobacter capsulatus sodB Gene, Encoding an Iron Superoxide Dismutase.

N. Cortez, N. Carrillo, C. Pasternak, A. Balzer, and G. Klug (1998)
J. Bacteriol. 180, 5413-5420
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Lower intracellular hydrogen peroxide levels in cells overexpressing CuZn-superoxide dismutase.

H. D. Teixeira, R. I. Schumacher, and R. Meneghini (1998)
PNAS 95, 7872-7875
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The Free Radical Theory of Aging Matures.

K. B. BECKMAN and B. N. AMES (1998)
Physiol Rev 78, 547-581
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Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats.

C. Leeuwenburgh, P. Hansen, A. Shaish, J. O. Holloszy, and J. W. Heinecke (1998)
Am J Physiol Regulatory Integrative Comp Physiol 274, R453-R461
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Psoralen photoactivation promotes morphological and functional changes in fibroblasts in vitro reminiscent of cellular senescence.

G Herrmann, P Brenneisen, M Wlaschek, J Wenk, K Faisst, G Quel, C Hommel, G Goerz, T Ruzicka, T Krieg, et al. (1998)
J. Cell Sci. 111, 759-767
 |  Abstract »  |  PDF »

Cloning, Expression, and Characterization of Two Manganese Superoxide Dismutases from Caenorhabditis elegans.

T. Hunter, W. H. Bannister, and G. J. Hunter (1997)
J. Biol. Chem. 272, 28652-28659
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Telomeres, Cancer, and Aging: Altering the Human Life Span.

D. A. Banks and M. Fossel (1997)
JAMA 278, 1345-1348
 |  Abstract »  |  PDF »

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