Science 28 January 1994: Vol. 263. no. 5146, pp. 526 - 529 DOI: 10.1126/science.8290962

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Articles

Binding of Extracellular Maspin to {beta}1 Integrins Inhibits Vascular Smooth Muscle Cell Migration.

R. Bass, L. Wagstaff, L. Ravenhill, and V. Ellis (2009)
J. Biol. Chem. 284, 27712-27720
 |  Abstract »  |  Full Text »  |  PDF »

Motility Induction in Breast Carcinoma by Mammary Epithelial Laminin 332 (Laminin 5).

P. M. Carpenter, A. V. Dao, Z. S. Arain, M. K. Chang, H. P. Nguyen, S. Arain, J. Wang-Rodriguez, S.-Y. Kwon, and S. P. Wilczynski (2009)
Mol. Cancer Res. 7, 462-475
 |  Abstract »  |  Full Text »  |  PDF »

Focused PCR Screen Reveals p53 Dependence of Nitric Oxide-Induced Apoptosis and Up-Regulation of Maspin and Plasminogen Activator Inhibitor-1 in Tumor Cells.

S. Lim, A. C. Hung, and A. G. Porter (2009)
Mol. Cancer Res. 7, 55-66
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Serpins in T cell immunity.

M. Bots and J. P. Medema (2008)
J. Leukoc. Biol. 84, 1238-1247
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Hot Topic: Prepubertal Ovariectomy Alters the Development of Myoepithelial Cells in the Bovine Mammary Gland.

K. Ballagh, N. Korn, L. Riggs, S. L. Pratt, F. Dessauge, R. M. Akers, and S. Ellis (2008)
J Dairy Sci 91, 2992-2995
 |  Abstract »  |  Full Text »  |  PDF »

RIN1 Is a Breast Tumor Suppressor Gene.

M. Milstein, C. K. Mooser, H. Hu, M. Fejzo, D. Slamon, L. Goodglick, S. Dry, and J. Colicelli (2007)
Cancer Res. 67, 11510-11516
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of Elafin in Normal and Tumor-Derived Mammary Epithelial Cells Is Mediated by CCAAT/Enhancer Binding Protein.

T. Yokota, T. Bui, Y. Liu, M. Yi, K. K. Hunt, and K. Keyomarsi (2007)
Cancer Res. 67, 11272-11283
 |  Abstract »  |  Full Text »  |  PDF »

Angiogenesis Inhibitors and the Need for Anti-angiogenic Therapeutics.

C.R. Dass, T.M.N. Tran, and P.F.M. Choong (2007)
Journal of Dental Research 86, 927-936
 |  Abstract »  |  Full Text »  |  PDF »

SERPINB11 Is a New Noninhibitory Intracellular Serpin: COMMON SINGLE NUCLEOTIDE POLYMORPHISMS IN THE SCAFFOLD IMPAIR CONFORMATIONAL CHANGE.

D. J. Askew, S. Cataltepe, V. Kumar, C. Edwards, S. M. Pace, R. N. Howarth, S. C. Pak, Y. S. Askew, D. Bromme, C. J. Luke, et al. (2007)
J. Biol. Chem. 282, 24948-24960
 |  Abstract »  |  Full Text »  |  PDF »

Maspin Binds to Urokinase-type and Tissue-type Plasminogen Activator through Exosite-Exosite Interactions.

M. Al-Ayyoubi, B. S. Schwartz, and P. G. W. Gettins (2007)
J. Biol. Chem. 282, 19502-19509
 |  Abstract »  |  Full Text »  |  PDF »

Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2.

J. Xue, D. Zhou, H. Yao, O. Gavrialov, M. J. McConnell, B. D. Gelb, and G. G. Haddad (2007)
Am J Physiol Regulatory Integrative Comp Physiol 292, R2406-R2416
 |  Abstract »  |  Full Text »  |  PDF »

Altered protein expression at early-stage rat hepatic neoplasia.

Q. Luo, L. Siconolfi-Baez, P. Annamaneni, M. T. Bielawski, P. M. Novikoff, and R. H. Angeletti (2007)
Am J Physiol Gastrointest Liver Physiol 292, G1272-G1282
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear and cytoplasmic Maspin expression in primary non-small cell lung cancer.

M. Woenckhaus, L. Bubendorf, P. Dalquen, J. Foerster, H. Blaszyk, M. Mirlacher, M. Soler, W. Dietmaier, G. Sauter, A. Hartmann, et al. (2007)
J. Clin. Pathol. 60, 483-486
 |  Abstract »  |  Full Text »  |  PDF »

Reduced Levels of ATF-2 Predispose Mice to Mammary Tumors.

T. Maekawa, T. Shinagawa, Y. Sano, T. Sakuma, S. Nomura, K. Nagasaki, Y. Miki, F. Saito-Ohara, J. Inazawa, T. Kohno, et al. (2007)
Mol. Cell. Biol. 27, 1730-1744
 |  Abstract »  |  Full Text »  |  PDF »

Simultaneous evaluation of maspin and CXCR4 in patients with breast cancer.

E. Tsoli, P. K Tsantoulis, A. Papalambros, B. Perunovic, D. England, D. A Rawlands, G. M Reynolds, D. Vlachodimitropoulos, S. L Morgan, C. A Spiliopoulou, et al. (2007)
J. Clin. Pathol. 60, 261-266
 |  Abstract »  |  Full Text »  |  PDF »

Convergence of p53 and Transforming Growth Factor beta (TGFbeta) Signaling on Activating Expression of the Tumor Suppressor Gene maspin in Mammary Epithelial Cells.

S. E. Wang, A. Narasanna, C. W. Whitell, F. Y. Wu, D. B. Friedman, and C. L. Arteaga (2007)
J. Biol. Chem. 282, 5661-5669
 |  Abstract »  |  Full Text »  |  PDF »

Multivariable Difference Gel Electrophoresis and Mass Spectrometry: A Case Study on Transforming Growth Factor-{beta} and ERBB2 Signaling.

D. B. Friedman, S. E. Wang, C. W. Whitwell, R. M. Caprioli, and C. L. Arteaga (2007)
Mol. Cell. Proteomics 6, 150-169
 |  Abstract »  |  Full Text »  |  PDF »

Maspin: The New Frontier.

Z. Khalkhali-Ellis (2006)
Clin. Cancer Res. 12, 7279-7283
 |  Abstract »  |  Full Text »  |  PDF »

Significance, detection and markers of disseminated breast cancer cells.

M. Lacroix (2006)
Endocr. Relat. Cancer 13, 1033-1067
 |  Abstract »  |  Full Text »  |  PDF »

Epigenetic regulation of maspin expression in the human placenta.

A. Dokras, J. Coffin, L. Field, A. Frakes, H. Lee, A. Madan, T. Nelson, G.-Y. Ryu, J.-G. Yoon, and A. Madan (2006)
Mol. Hum. Reprod. 12, 611-617
 |  Abstract »  |  Full Text »  |  PDF »

Endogenous inhibition of histone deacetylase 1 by tumor-suppressive maspin..

X. Li, S. Yin, Y. Meng, W. Sakr, and S. Sheng (2006)
Cancer Res. 66, 9323-9329
 |  Abstract »  |  Full Text »  |  PDF »

Maspin is physically associated with {beta}1 integrin regulating cell adhesion in mammary epithelial cells.

N. Cella, A. Contreras, K. Latha, J. M. Rosen, and M. Zhang (2006)
FASEB J 20, 1510-1512
 |  Abstract »  |  Full Text »  |  PDF »

The Regulation of Exosome Secretion: a Novel Function of the p53 Protein..

X. Yu, S. L. Harris, and A. J. Levine (2006)
Cancer Res. 66, 4795-4801
 |  Abstract »  |  Full Text »  |  PDF »

Maspin Retards Cell Detachment via a Novel Interaction with the Urokinase-Type Plasminogen Activator/Urokinase-Type Plasminogen Activator Receptor System..

S. Yin, J. Lockett, Y. Meng, H. Biliran Jr., G. E. Blouse, X. Li, N. Reddy, Z. Zhao, X. Lin, J. Anagli, et al. (2006)
Cancer Res. 66, 4173-4181
 |  Abstract »  |  Full Text »  |  PDF »

Aberrant maspin expression in gallbladder epithelium is associated with intestinal metaplasia in patients with cholelithiasis..

C Maesawa, S Ogasawara, A Yashima-Abo, T Kimura, K Kotani, S Masuda, Y Nagata, T Iwaya, K Suzuki, T Oyake, et al. (2006)
J. Clin. Pathol. 59, 328-330
 |  Abstract »  |  Full Text »  |  PDF »

Headpin: A Serpin with Endogenous and Exogenous Suppression of Angiogenesis.

T. D. Shellenberger, A. Mazumdar, Y. Henderson, K. Briggs, M. Wang, C. Chattopadhyay, A. Jayakumar, M. Frederick, and G. L. Clayman (2005)
Cancer Res. 65, 11501-11509
 |  Abstract »  |  Full Text »  |  PDF »

Maspin expression in carcinoma ex pleomorphic adenoma.

M T Martins, A Altemani, L Freitas, and V C Araujo (2005)
J. Clin. Pathol. 58, 1311-1314
 |  Abstract »  |  Full Text »  |  PDF »

Tumor-suppressive Maspin Regulates Cell Response to Oxidative Stress by Direct Interaction with Glutathione S-Transferase.

S. Yin, X. Li, Y. Meng, R. L. Finley Jr., W. Sakr, H. Yang, N. Reddy, and S. Sheng (2005)
J. Biol. Chem. 280, 34985-34996
 |  Abstract »  |  Full Text »  |  PDF »

Mammary Serine Protease Inhibitor (Maspin) Binds Directly to Interferon Regulatory Factor 6: IDENTIFICATION OF A NOVEL SERPIN PARTNERSHIP.

C. M. Bailey, Z. Khalkhali-Ellis, S. Kondo, N. V. Margaryan, R. E. B. Seftor, W. W. Wheaton, S. Amir, M. R. Pins, B. C. Schutte, and M. J. C. Hendrix (2005)
J. Biol. Chem. 280, 34210-34217
 |  Abstract »  |  Full Text »  |  PDF »

The High Resolution Crystal Structure of the Human Tumor Suppressor Maspin Reveals a Novel Conformational Switch in the G-helix.

R. H. P. Law, J. A. Irving, A. M. Buckle, K. Ruzyla, M. Buzza, T. A. Bashtannyk-Puhalovich, T. C. Beddoe, K. Nguyen, D. M. Worrall, S. P. Bottomley, et al. (2005)
J. Biol. Chem. 280, 22356-22364
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Maspin in Mammary Gland Tumors of the Dog.

A. Espinosa de los Monteros, M. Y. Millan, G. A. Ramirez, J. Ordas, C. Reymundo, and J. Martin de las Mulas (2005)
Vet. Pathol. 42, 250-257
 |  Abstract »  |  Full Text »  |  PDF »

Maspin Mediates Increased Tumor Cell Apoptosis upon Induction of the Mitochondrial Permeability Transition.

K. Latha, W. Zhang, N. Cella, H. Y. Shi, and M. Zhang (2005)
Mol. Cell. Biol. 25, 1737-1748
 |  Abstract »  |  Full Text »  |  PDF »

Prognostic Significance of the Tumor Suppressor Gene Maspin in Non-Small Cell Lung Cancer.

K. Hirai, K. Koizumi, S. Haraguchi, T. Hirata, I. Mikami, M. Fukushima, S. Yamagishi, T. Kawashima, D. Okada, K. Shimizu, et al. (2005)
Ann. Thorac. Surg. 79, 248-253
 |  Abstract »  |  Full Text »  |  PDF »

Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: REACTIVE CENTER LOOP OF MASPIN IS EXPOSED BUT CONSTRAINED.

M. Al-Ayyoubi, P. G. W. Gettins, and K. Volz (2004)
J. Biol. Chem. 279, 55540-55544
 |  Abstract »  |  Full Text »  |  PDF »

Maspin Expression Is Transactivated by p63 and Is Critical for the Modulation of Lung Cancer Progression.

S. Kim, J. Han, J. Kim, and C. Park (2004)
Cancer Res. 64, 6900-6905
 |  Abstract »  |  Full Text »  |  PDF »

Discrepancy between mRNA and protein expression of tumour suppressor maspin in synovial tissue may contribute to synovial hyperplasia in rheumatoid arthritis.

J Schedel, O Distler, M Woenckhaus, R E Gay, B Simmen, B A Michel, U Muller-Ladner, and S Gay (2004)
Ann Rheum Dis 63, 1205-1211
 |  Abstract »  |  Full Text »  |  PDF »

Mammaglobin Expression in Leukapheresis Products Is a Predictive Marker of Poor Prognosis in Women with High-Risk Breast Cancer.

P. F. Ferrucci, C. Rabascio, C. Mazzetta, E. Cocorocchio, A. Agazzi, A. Vanazzi, S. Cinieri, F. A. Peccatori, M. Paolucci, F. Bertolini, et al. (2004)
Clin. Cancer Res. 10, 6039-6046
 |  Abstract »  |  Full Text »  |  PDF »

Do antiangiogenic protein fragments have amyloid properties?.

M. F. B. G. Gebbink, E. E. Voest, and A. Reijerkerk (2004)
Blood 104, 1601-1605
 |  Abstract »  |  Full Text »  |  PDF »

Hormonal Defect in Maspin Heterozygous Mice Reveals a Role of Progesterone in Pubertal Ductal Development.

H. Y. Shi, J. P. Lydon, and M. Zhang (2004)
Mol. Endocrinol. 18, 2196-2207
 |  Abstract »  |  Full Text »  |  PDF »

Decreased Pigment Epithelium-Derived Factor Is Associated with Metastatic Phenotype in Human and Rat Prostate Tumors.

S. Halin, P. Wikstrom, S. H. Rudolfsson, P. Stattin, J. A. Doll, S. E. Crawford, and A. Bergh (2004)
Cancer Res. 64, 5664-5671
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Suppressor Maspin Is Up-Regulated during Keratinocyte Senescence, Exerting a Paracrine Antiangiogenic Activity.

B. J. Nickoloff, M. W. Lingen, B.-D. Chang, M. Shen, M. Swift, J. Curry, P. Bacon, B. Bodner, and I. B. Roninson (2004)
Cancer Res. 64, 2956-2961
 |  Abstract »  |  Full Text »  |  PDF »

Maspin plays an essential role in early embryonic development.

F. Gao, H. Y. Shi, C. Daughty, N. Cella, and M. Zhang (2004)
Development 131, 1479-1489
 |  Abstract »  |  Full Text »  |  PDF »

Bax Mediates the Apoptosis-Sensitizing Effect of Maspin.

J. Liu, S. Yin, N. Reddy, C. Spencer, and S. Sheng (2004)
Cancer Res. 64, 1703-1711
 |  Abstract »  |  Full Text »  |  PDF »

Regulating the Tumor Suppressor Gene Maspin in Breast Cancer Cells: A Potential Mechanism for the Anticancer Properties of Tamoxifen.

Z. Khalkhali-Ellis, A. L. Christian, D. A. Kirschmann, E. M. Edwards, M. Rezaie-Thompson, M. A. Vasef, L. M. Gruman, R. E. B. Seftor, L. E. Norwood, and M. J. C. Hendrix (2004)
Clin. Cancer Res. 10, 449-454
 |  Abstract »  |  Full Text »  |  PDF »

Cell-Type-Specific Repression of the Maspin Gene Is Disrupted Frequently by Demethylation at the Promoter Region in Gastric Intestinal Metaplasia and Cancer Cells.

Y. Akiyama, C. Maesawa, S. Ogasawara, M. Terashima, and T. Masuda (2003)
Am. J. Pathol. 163, 1911-1919
 |  Abstract »  |  Full Text »  |  PDF »

Sufficiency of the Reactive Site Loop of Maspin for Induction of Cell-Matrix Adhesion and Inhibition of Cell Invasion: CONVERSION OF OVALBUMIN TO A MASPIN-LIKE MOLECULE.

C. Ngamkitidechakul, D. J. Warejcka, J. M. Burke, W. J. O'Brien, and S. S. Twining (2003)
J. Biol. Chem. 278, 31796-31806
 |  Abstract »  |  Full Text »  |  PDF »

Pdef Expression in Human Breast Cancer Is Correlated with Invasive Potential and Altered Gene Expression.

R. J. Feldman, V. I. Sementchenko, M. Gayed, M. M. Fraig, and D. K. Watson (2003)
Cancer Res. 63, 4626-4631
 |  Abstract »  |  Full Text »  |  PDF »

Identification of 9 Genes Differentially Expressed in Head and Neck Squamous Cell Carcinoma.

H. E. Gonzalez, M. Gujrati, M. Frederick, Y. Henderson, J. Arumugam, P. W. Spring, K. Mitsudo, H.-W. Kim, and G. L. Clayman (2003)
Arch Otolaryngol Head Neck Surg 129, 754-759
 |  Abstract »  |  Full Text »  |  PDF »

Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis.

M. L. Cher, H. R. Biliran Jr., S. Bhagat, Y. Meng, M. Che, J. Lockett, J. Abrams, R. Fridman, M. Zachareas, and S. Sheng (2003)
PNAS 100, 7847-7852
 |  Abstract »  |  Full Text »  |  PDF »

Modeling tissue-specific signaling and organ function in three dimensions.

K. L. Schmeichel and M. J. Bissell (2003)
J. Cell Sci. 116, 2377-2388
 |  Abstract »  |  Full Text »  |  PDF »

Amyloid Endostatin Induces Endothelial Cell Detachment by Stimulation of the Plasminogen Activation System.

A. Reijerkerk, L. O. Mosnier, O. Kranenburg, B. N. Bouma, P. Carmeliet, T. Drixler, J. C.M. Meijers, E. E. Voest, and M. F.B.G. Gebbink (2003)
Mol. Cancer Res. 1, 561-568
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide Regulation of Maspin Expression in Normal Mammary Epithelial and Breast Cancer Cells.

Z. Khalkhali-Ellis and M. J. C. Hendrix (2003)
Am. J. Pathol. 162, 1411-1417
 |  Abstract »  |  Full Text »  |  PDF »

Maspin Inhibits Cell Migration in the Absence of Protease Inhibitory Activity.

R. Bass, A.-M. M. Fernandez, and V. Ellis (2002)
J. Biol. Chem. 277, 46845-46848
 |  Abstract »  |  Full Text »  |  PDF »

Distribution of the Human Intracellular Serpin Protease Inhibitor 8 in Human Tissues.

M. C. Strik, B. A. Bladergroen, D. Wouters, W. Kisiel, J. H. Hooijberg, A. R. Verlaan, P. L. Hordijk, P. Schneider, C. E. Hack, and J. A. Kummer (2002)
J. Histochem. Cytochem. 50, 1443-1454
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Confirmation of a Module of Coexpressed Genes.

H. G. R. Thompson, J. W. Harris, B. J. Wold, S. R. Quake, and J. P. Brody (2002)
Genome Res. 12, 1517-1522
 |  Abstract »  |  Full Text »  |  PDF »

Investigation in Liver Tissues and Cell Lines of the Transcription of 13 Genes Mapping to the 16q24 Region That Are Frequently Deleted in Hepatocellular Carcinoma.

P. Riou, R. Saffroy, J. Comoy, M. Gross-Goupil, J.-P. Thiery, J.-F. Emile, D. Azoulay, D. Piatier-Tonneau, A. Lemoine, and B. Debuire (2002)
Clin. Cancer Res. 8, 3178-3186
 |  Abstract »  |  Full Text »  |  PDF »

The Paradoxical Expression of Maspin in Ovarian Carcinoma.

A. K. Sood, M. S. Fletcher, L. M. Gruman, J. E. Coffin, S. Jabbari, Z. Khalkhali-Ellis, N. Arbour, E. A. Seftor, and M. J. C. Hendrix (2002)
Clin. Cancer Res. 8, 2924-2932
 |  Abstract »  |  Full Text »  |  PDF »

Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness.

N. Jessani, Y. Liu, M. Humphrey, and B. F. Cravatt (2002)
PNAS 99, 10335-10340
 |  Abstract »  |  Full Text »  |  PDF »

Maspin Expression Profile in Human Prostate Cancer (CaP) and in Vitro Induction of Maspin Expression by Androgen Ablation.

Z. Zou, W. Zhang, D. Young, M. G. Gleave, P. Rennie, T. Connell, R. Connelly, J. Moul, S. Srivastava, and I. Sesterhenn (2002)
Clin. Cancer Res. 8, 1172-1177
 |  Abstract »  |  Full Text »  |  PDF »

Functional Diversification During Evolution of the Murine {alpha}1-Proteinase Inhibitor Family: Role of the Hypervariable Reactive Center Loop.

K. W. Barbour, R. L. Goodwin, F. Guillonneau, Y. Wang, H. Baumann, and F. G. Berger (2002)
Mol. Biol. Evol. 19, 718-727
 |  Abstract »  |  Full Text »  |  PDF »

Plasminogen activator inhibitor type 2: a regulator of monocyte proliferation and differentiation.

H. Yu, F. Maurer, and R. L. Medcalf (2002)
Blood 99, 2810-2818
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for a Direct Interaction between the Tumor Suppressor Serpin, Maspin, and Types I and III Collagen.

O. E. Blacque and D. M. Worrall (2002)
J. Biol. Chem. 277, 10783-10788
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: a novel protective mechanism for tumor cells to circumvent the immune system?.

B. A. Bladergroen, C. J. L. M. Meijer, R. L. ten Berge, C. E. Hack, J. J. F. Muris, D. F. Dukers, A. Chott, Y. Kazama, J. J. Oudejans, O. van Berkum, et al. (2002)
Blood 99, 232-237
 |  Abstract »  |  Full Text »  |  PDF »

Maspin: Synthesis by Human Cornea and Regulation of In Vitro Stromal Cell Adhesion to Extracellular Matrix.

C. Ngamkitidechakul, J. M. Burke, W. J. O'Brien, and S. S. Twining (2001)
Invest. Ophthalmol. Vis. Sci. 42, 3135-3141
 |  Abstract »  |  Full Text »  |  PDF »

Pleiotrophic Inhibition of Pericellular Urokinase-type Plasminogen Activator System by Endogenous Tumor Suppressive Maspin.

H. Biliran Jr. and S. Sheng (2001)
Cancer Res. 61, 8676-8682
 |  Abstract »  |  Full Text »  |  PDF »

Blocking Tumor Growth, Invasion, and Metastasis by Maspin in a Syngeneic Breast Cancer Model.

H. Y Shi, W. Zhang, R. Liang, S. Abraham, F. S. Kittrell, D. Medina, and M. Zhang (2001)
Cancer Res. 61, 6945-6951
 |  Abstract »  |  Full Text »  |  PDF »

Nucleocytoplasmic Distribution of the Ovalbumin Serpin PI-9 Requires a Nonconventional Nuclear Import Pathway and the Export Factor Crm1.

C. H. Bird, E. J. Blink, C. E. Hirst, M. S. Buzza, P. M. Steele, J. Sun, D. A. Jans, and P. I. Bird (2001)
Mol. Cell. Biol. 21, 5396-5407
 |  Abstract »  |  Full Text »  |  PDF »

Microvillar cell surface as a natural defense system against xenobiotics: a new interpretation of multidrug resistance.

K. Lange and J. Gartzke (2001)
Am J Physiol Cell Physiol 281, C369-C385
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the Tumor Suppressor Gene Maspin in Human Pancreatic Cancers.

N. Maass, T. Hojo, M. Ueding, J. Lüttges, G. Klöppel, W. Jonat, and K. Nagasaki (2001)
Clin. Cancer Res. 7, 812-817
 |  Abstract »  |  Full Text »

Expression of Tissue Factor Pathway Inhibitor 2 Inversely Correlates during the Progression of Human Gliomas.

C. N. Rao, S. S. Lakka, Y. Kin, S. D. Konduri, G. N. Fuller, S. Mohanam, and J. S. Rao (2001)
Clin. Cancer Res. 7, 570-576
 |  Abstract »  |  Full Text »

A Novel Serine-dependent Proteolytic Activity Is Responsible for Truncated Signal Transducer and Activator of Transcription Proteins in Acute Myeloid Leukemia Blasts.

Z. Xia, R. R. Salzler, D. P. Kunz, M. R. Baer, L. Kazim, H. Baumann, and M. Wetzler (2001)
Cancer Res. 61, 1747-1753
 |  Abstract »  |  Full Text »

Metastasis-Suppressor Genes: a Review and Perspective on an Emerging Field.

B. A. Yoshida, M. M. Sokoloff, D. R. Welch, and C. W. Rinker-Schaeffer (2000)
J Natl Cancer Inst 92, 1717-1730
 |  Abstract »  |  Full Text »  |  PDF »

The necrotic Gene in Drosophila Corresponds to One of a Cluster of Three Serpin Transcripts Mapping at 43A1.2.

C. Green, E. Levashina, C. McKimmie, T. Dafforn, J.-M. Reichhart, and D. Gubb (2000)
Genetics 156, 1117-1127
 |  Abstract »  |  Full Text »

The Serpin Secreted by Brugia malayi Microfilariae, Bm-SPN-2, Elicits Strong, but Short-Lived, Immune Responses in Mice and Humans.

X. Zang, A. K. Atmadja, P. Gray, J. E. Allen, C. A. Gray, R. A. Lawrence, M. Yazdanbakhsh, and R. M. Maizels (2000)
J. Immunol. 165, 5161-5169
 |  Abstract »  |  Full Text »  |  PDF »

Detection of Circulating Tumor by Reverse Transcriptase Polymerase Chain Reaction.

J.-C. Goeminne, T. Guillaume, M. Federico, R. Sabbatini, M. Morselli, R. Depenni, K. Cagossi, M. Luppi, G. Torelli, and V. Silingardi (2000)
J. Clin. Oncol. 18, 3196-3197
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The Surface of Prostate Carcinoma DU145 Cells Mediates the Inhibition of Urokinase-type Plasminogen Activator by Maspin.

R. McGowen, H. Biliran Jr., R. Sager, and S. Sheng (2000)
Cancer Res. 60, 4771-4778
 |  Abstract »  |  Full Text »

Detection of Circulating Tumor Cells by Reverse Transcriptase Polymerase Chain Reaction of Maspin in Patients With Breast Cancer Undergoing Conventional-Dose Chemotherapy.

R. Sabbatini, M. Federico, M. Morselli, R. Depenni, K. Cagossi, M. Luppi, G. Torelli, and V. Silingardi (2000)
J. Clin. Oncol. 18, 1914-1920
 |  Abstract »  |  Full Text »  |  PDF »

Linking Gene Expression Patterns to Therapeutic Groups in Breast Cancer.

K. J. Martin, B. M. Kritzman, L. M. Price, B. Koh, C.-P. Kwan, X. Zhang, A. Mackay, M. J. O’Hare, C. M. Kaelin, G. L. Mutter, et al. (2000)
Cancer Res. 60, 2232-2238
 |  Abstract »  |  Full Text »

AZU-1: A Candidate Breast Tumor Suppressor and Biomarker for Tumor Progression.

H.-M. Chen, K. L. Schmeichel, I. S. Mian, S. Lelièvre, O. W. Petersen, and M. J. Bissell (2000)
Mol. Biol. Cell 11, 1357-1367
 |  Abstract »  |  Full Text »

Characterization of a Human Angiotensinogen Cleaved in Its Reactive Center Loop by a Proteolytic Activity from Chinese Hamster Ovary Cells.

J. Celerier, G. Schmid, J.-P. Le Caer, A.-P. Gimenez-Roqueplo, D. Bur, A. Friedlein, H. Langen, P. Corvol, and X. Jeunemaitre (2000)
J. Biol. Chem. 275, 10648-10654
 |  Abstract »  |  Full Text »  |  PDF »

p53 Regulates the Expression of the Tumor Suppressor Gene Maspin.

Z. Zou, C. Gao, A. K. Nagaich, T. Connell, S.'i. Saito, J. W. Moul, P. Seth, E. Appella, and S. Srivastava (2000)
J. Biol. Chem. 275, 6051-6054
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Megsin mRNA, a Novel Mesangium-Predominant Gene, in the Renal Tissues of Various Glomerular Diseases.

D. SUZUKI, T. MIYATA, M. NANGAKU, H. TAKANO, N. SAOTOME, M. TOYODA, Y. MORI, S.-Y. ZHANG, R. INAGI, M. ENDOH, et al. (1999)
J. Am. Soc. Nephrol. 10, 2606-2613
 |  Abstract »  |  Full Text »

Three-state Unfolding and Self-association of Maspin, a Tumor-suppressing Serpin.

T. Liu, P. A. Pemberton, and A. D. Robertson (1999)
J. Biol. Chem. 274, 29628-29632
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Serpin Expressed by Blood-Borne Microfilariae of the Parasitic Nematode Brugia malayi Inhibits Human Neutrophil Serine Proteinases.

X. Zang, M. Yazdanbakhsh, H. Jiang, M. R. Kanost, and R. M. Maizels (1999)
Blood 94, 1418-1428
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Nuclear Targeting Domain in the Insertion between Helices C and D in Protease Inhibitor-10.

T. L. Chuang and R. R. Schleef (1999)
J. Biol. Chem. 274, 11194-11198
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Cloning of a Candidate Tumor Suppressor Gene, DLC1, from Chromosome 3p21.3.

Y. Daigo, T. Nishiwaki, T. Kawasoe, M. Tamari, E. Tsuchiya, and Y. Nakamura (1999)
Cancer Res. 59, 1966-1972
 |  Abstract »  |  Full Text »  |  PDF »

The Intracellular Serpin Proteinase Inhibitor 6 Is Expressed in Monocytes and Granulocytes and Is a Potent Inhibitor of the Azurophilic Granule Protease, Cathepsin G.

F. L. Scott, C. E. Hirst, J. Sun, C. H. Bird, S. P. Bottomley, and P. I. Bird (1999)
Blood 93, 2089-2097
 |  Abstract »  |  Full Text »  |  PDF »

The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival.

K. M. Dougherty, J. M. Pearson, A. Y. Yang, R. J. Westrick, M. S. Baker, and D. Ginsburg (1999)
PNAS 96, 686-691
 |  Abstract »  |  Full Text »  |  PDF »

Breast and Prostate Cancer: An Analysis of Common Epidemiological, Genetic, and Biochemical Features.

C. Lopez-Otin and E. P. Diamandis (1998)
Endocr. Rev. 19, 365-396
 |  Abstract »  |  Full Text »  |  PDF »

Isolation, Purification, and Characterization of a Collagen-associated Serpin, Caspin, Produced by Murine Colon Adenocarcinoma Cells.

K.-i. Kozaki, O. Miyaishi, O. Koiwai, Y. Yasui, A. Kashiwai, Y. Nishikawa, S. Shimizu, and S. Saga (1998)
J. Biol. Chem. 273, 15125-15130
 |  Abstract »  |  Full Text »  |  PDF »

The Serine Proteinase Inhibitor (Serpin) Plasminogen Activation Inhibitor Type 2 Protects against Viral Cytopathic Effects by Constitutive Interferon {alpha}/{beta} Priming.

T. M. Antalis, M. La Linn, K. Donnan, L. Mateo, J. Gardner, J. L. Dickinson, K. Buttigieg, and A. Suhrbier (1998)
J. Exp. Med. 187, 1799-1811
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Bomapin, a Novel Human Serpin, in Normal/Malignant Hematopoiesis and in the Monocytic Cell Lines THP-1 and AML-193.

M. Riewald, T. Chuang, A. Neubauer, H. Riess, and R. R. Schleef (1998)
Blood 91, 1256-1262
 |  Abstract »  |  Full Text »  |  PDF »

Tissue-type plasminogen activator is a target of the tumor suppressor gene maspin.

S. Sheng, B. Truong, D. Fredrickson, R. Wu, A. B. Pardee, and R. Sager (1998)
PNAS 95, 499-504
 |  Abstract »  |  Full Text »  |  PDF »

Maspin Is an Intracellular Serpin That Partitions into Secretory Vesicles and Is Present at the Cell Surface.

P. A. Pemberton, A. R. Tipton, N. Pavloff, J. Smith, J. R. Erickson, Z. M. Mouchabeck, and M. C. Kiefer (1997)
J. Histochem. Cytochem. 45, 1697-1706
 |  Abstract »  |  Full Text »  |  PDF »

Purification, cDNA Cloning, and Characterization of a New Serpin with Megakaryocyte Maturation Activity.

M. Tsujimoto, N. Tsuruoka, N. Ishida, T. Kurihara, F. Iwasa, K. Yamashiro, T. Rogi, S. Kodama, N. Katsuragi, M. Adachi, et al. (1997)
J. Biol. Chem. 272, 15373-15380
 |  Abstract »  |  Full Text »  |  PDF »

A New Family of 10 Murine Ovalbumin Serpins Includes Two Homologs of Proteinase Inhibitor 8 and Two Homologs of the Granzyme B Inhibitor (Proteinase Inhibitor 9).

J. Sun, L. Ooms, C. H. Bird, V. R. Sutton, J. A. Trapani, and P. I. Bird (1997)
J. Biol. Chem. 272, 15434-15441
 |  Abstract »  |  Full Text »  |  PDF »

Expression of maspin in prostate cells is regulated by a positive Ets element and a negative hormonal responsive element site recognized by androgen receptor.

M. Zhang, D. Magit, and R. Sager (1997)
PNAS 94, 5673-5678
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}1-Antitrypsin Blocks the Release of Transforming Growth Factor-{alpha} from MCF-7 Human Breast Cancer Cells.

J. Yavelow, A. Tuccillo, S. S. Kadner, J. Katz, and T. H. Finlay (1997)
J. Clin. Endocrinol. Metab. 82, 745-752
 |  Abstract »  |  Full Text »  |  PDF »

Growth-inhibitory Activity and Downregulation of the Class II Tumor-suppressor Gene H-rev107 in Tumor Cell Lines and Experimental Tumors.

C. Sers, U. Emmenegger, K. Husmann, K. Bucher, A.-C. Andres, and R. Schafer (1997)
J. Cell Biol. 136, 935-944
 |  Abstract »  |  Full Text »  |  PDF »

Expression genetics in cancer: Shifting the focus from DNA to RNA.

R. Sager (1997)
PNAS 94, 952-955
 |  Abstract »  |  Full Text »  |  PDF »

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