Science 12 November 1993: Vol. 262. no. 5136, pp. 1069 - 1072 DOI: 10.1126/science.7694367

Prev | Table of Contents | Next

Articles

Increased Mitogen-Activated Protein Kinase Kinase/Extracellularly Regulated Kinase Activity in Human Endometrial Stromal Fibroblasts of Women with Endometriosis Reduces 3',5'-Cyclic Adenosine 5'-Monophosphate Inhibition of Cyclin D1.

M. C. Velarde, L. Aghajanova, C. R. Nezhat, and L. C. Giudice (2009)
Endocrinology 150, 4701-4712
 |  Abstract »  |  Full Text »  |  PDF »

Fibrinogen binding to ICAM-1 promotes EGFR-dependent mucin production in human airway epithelial cells.

S. Kim and J. A. Nadel (2009)
Am J Physiol Lung Cell Mol Physiol 297, L174-L183
 |  Abstract »  |  Full Text »  |  PDF »

Long-Term Culture and Growth Kinetics of Murine Corneal Epithelial Cells Expanded from Single Corneas.

X. Ma, S. Shimmura, H. Miyashita, S. Yoshida, M. Kubota, T. Kawakita, and K. Tsubota (2009)
Invest. Ophthalmol. Vis. Sci. 50, 2716-2721
 |  Abstract »  |  Full Text »  |  PDF »

Human Uterine Smooth Muscle and Leiomyoma Cells Differ in Their Rapid 17{beta}-Estradiol Signaling: Implications for Proliferation.

E. N. Nierth-Simpson, M. M. Martin, T.-C. Chiang, L. I. Melnik, L. V. Rhodes, S. E. Muir, M. E. Burow, and J. A. McLachlan (2009)
Endocrinology 150, 2436-2445
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic AMP Inhibits the Proliferation of Thyroid Carcinoma Cell Lines through Regulation of CDK4 Phosphorylation.

A. S. Rocha, S. Paternot, K. Coulonval, J. E. Dumont, P. Soares, and P. P. Roger (2008)
Mol. Biol. Cell 19, 4814-4825
 |  Abstract »  |  Full Text »  |  PDF »

The influence of methylmercury on the nitric oxide production of alveolar macrophages.

T. Kuo (2008)
Toxicology and Industrial Health 24, 531-538
 |  Abstract »  |  PDF »

Network topology determines dynamics of the mammalian MAPK1,2 signaling network: bifan motif regulation of C-Raf and B-Raf isoforms by FGFR and MC1R.

M. Muller, M. Obeyesekere, G. B. Mills, and P. T. Ram (2008)
FASEB J 22, 1393-1403
 |  Abstract »  |  Full Text »  |  PDF »

Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats.

H. Obata, Y. Sakai, S. Ohnishi, S. Takeshita, H. Mori, M. Kodama, K. Kangawa, Y. Aizawa, and N. Nagaya (2008)
Am. J. Respir. Crit. Care Med. 177, 195-201
 |  Abstract »  |  Full Text »  |  PDF »

Role of cAMP inhibition of p44/p42 mitogen-activated protein kinase in potentiation of protein secretion in rat lacrimal gland.

C. Funaki, R. R. Hodges, and D. A. Dartt (2007)
Am J Physiol Cell Physiol 293, C1551-C1560
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic Adenosine 3',5'Monophosphate/Protein Kinase A and Mitogen-Activated Protein Kinase 3/1 Pathways Are Involved in Adenylate Cyclase-Activating Polypeptide 1-Induced Common Alpha-Glycoprotein Subunit Gene (Cga) Expression in Mouse Pituitary Gonadotroph LbetaT2 Cells.

T. Harada, H. Kanasaki, S. Mutiara, A. Oride, and K. Miyazaki (2007)
Biol Reprod 77, 707-716
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic AMP-Dependent, Protein Kinase A-Independent Activation of Extracellular Signal-Regulated Kinase 1/2 Following Adenosine Receptor Stimulation in Human Umbilical Vein Endothelial Cells: Role of Exchange Protein Activated by cAMP 1 (Epac1).

Y. Fang and M. E. Olah (2007)
J. Pharmacol. Exp. Ther. 322, 1189-1200
 |  Abstract »  |  Full Text »  |  PDF »

Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2.

C. A. Barlow, T. F. Barrett, A. Shukla, B. T. Mossman, and K. M. Lounsbury (2007)
Am J Physiol Lung Cell Mol Physiol 292, L1361-L1369
 |  Abstract »  |  Full Text »  |  PDF »

In Melanoma, RAS Mutations Are Accompanied by Switching Signaling from BRAF to CRAF and Disrupted Cyclic AMP Signaling.

N. Dumaz, R. Hayward, J. Martin, L. Ogilvie, D. Hedley, J. A. Curtin, B. C. Bastian, C. Springer, and R. Marais (2006)
Cancer Res. 66, 9483-9491
 |  Abstract »  |  Full Text »  |  PDF »

CUTL1 Is Phosphorylated by Protein Kinase A, Modulating Its Effects on Cell Proliferation and Motility.

P. Michl, B. Knobel, and J. Downward (2006)
J. Biol. Chem. 281, 15138-15144
 |  Abstract »  |  Full Text »  |  PDF »

Beyond the dogma: novel {beta}2-adrenoceptor signalling in the airways..

M. A. Giembycz and R. Newton (2006)
Eur. Respir. J. 27, 1286-1306
 |  Abstract »  |  Full Text »  |  PDF »

The GNAS1 T393C Polymorphism Predicts Survival in Patients with Clear Cell Renal Cell Carcinoma.

U. H. Frey, G. Lummen, T. Jager, K.-H. Jockel, K. W. Schmid, H. Rubben, N. Muller, W. Siffert, and A. Eisenhardt (2006)
Clin. Cancer Res. 12, 759-763
 |  Abstract »  |  Full Text »  |  PDF »

Pituitary tumour pathogenesis..

A. P. Heaney (2006)
Br. Med. Bull. 75-76, 81-97
 |  Abstract »  |  Full Text »  |  PDF »

Type I Collagen Structure Regulates Cell Morphology and EGF Signaling in Primary Rat Hepatocytes through cAMP-dependent Protein Kinase A.

J. Fassett, D. Tobolt, and L. K. Hansen (2006)
Mol. Biol. Cell 17, 345-356
 |  Abstract »  |  Full Text »  |  PDF »

Epac Activation Converts cAMP from a Proliferative into a Differentiation Signal in PC12 Cells.

S. Kiermayer, R. M. Biondi, J. Imig, G. Plotz, J. Haupenthal, S. Zeuzem, and A. Piiper (2005)
Mol. Biol. Cell 16, 5639-5648
 |  Abstract »  |  Full Text »  |  PDF »

Formation of E-Cadherin-Mediated Cell-Cell Adhesion Activates Akt and Mitogen Activated Protein Kinase via Phosphatidylinositol 3 Kinase and Ligand-Independent Activation of Epidermal Growth Factor Receptor in Ovarian Cancer Cells.

P. Reddy, L. Liu, C. Ren, P. Lindgren, K. Boman, Y. Shen, E. Lundin, U. Ottander, M. Rytinki, and K. Liu (2005)
Mol. Endocrinol. 19, 2564-2578
 |  Abstract »  |  Full Text »  |  PDF »

Raf: A Strategic Target for Therapeutic Development Against Cancer.

M. Beeram, A. Patnaik, and E. K. Rowinsky (2005)
J. Clin. Oncol. 23, 6771-6790
 |  Abstract »  |  Full Text »  |  PDF »

Human Telomerase Reverse Transcriptase Immortalizes Bovine Lens Epithelial Cells and Suppresses Differentiation through Regulation of the ERK Signaling Pathway.

J. Wang, H. Feng, X.-Q. Huang, H. Xiang, Y.-W. Mao, J.-P. Liu, Q. Yan, W.-B. Liu, Y. Liu, M. Deng, et al. (2005)
J. Biol. Chem. 280, 22776-22787
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Inhibitor of Metalloproteinase-2 Promotes Neuronal Differentiation by Acting as an Anti-Mitogenic Signal.

L. Perez-Martinez and D. M. Jaworski (2005)
J. Neurosci. 25, 4917-4929
 |  Abstract »  |  Full Text »  |  PDF »

Cell Signaling through the Protein Kinases cAMP-dependent Protein Kinase, Protein Kinase C{epsilon}, and RAF-1 Regulates Amphotropic Murine Leukemia Virus Envelope Protein-induced Syncytium Formation.

W. Wang, Z. Jobbagy, T. H. Bird, M. V. Eiden, and W. B. Anderson (2005)
J. Biol. Chem. 280, 16772-16783
 |  Abstract »  |  Full Text »  |  PDF »

The T393C Polymorphism of the G{alpha}s Gene (GNAS1) Is a Novel Prognostic Marker in Bladder Cancer.

U. H. Frey, A. Eisenhardt, G. Lummen, H. Rubben, K.-H. Jockel, K. W. Schmid, and W. Siffert (2005)
Cancer Epidemiol. Biomarkers Prev. 14, 871-877
 |  Abstract »  |  Full Text »  |  PDF »

Co-activation of ERK, NF-{kappa}B, and GADD45{beta} in Response to Ionizing Radiation.

T. Wang, Y.-C. Hu, S. Dong, M. Fan, D. Tamae, M. Ozeki, Q. Gao, D. Gius, and J. J. Li (2005)
J. Biol. Chem. 280, 12593-12601
 |  Abstract »  |  Full Text »  |  PDF »

Insulin-Like Growth Factor 1 Inhibits Extracellular Signal-Regulated Kinase to Promote Neuronal Survival via the Phosphatidylinositol 3-Kinase/Protein Kinase A/c-Raf Pathway.

S. Subramaniam, N. Shahani, J. Strelau, C. Laliberte, R. Brandt, D. Kaplan, and K. Unsicker (2005)
J. Neurosci. 25, 2838-2852
 |  Abstract »  |  Full Text »  |  PDF »

Differential regulation of mesangial cell mitogenesis by cAMP phosphodiesterase isozymes 3 and 4.

J. Cheng, M. A. Thompson, H. J. Walker, C. E. Gray, M. M. Diaz Encarnacion, G. M. Warner, and J. P. Grande (2004)
Am J Physiol Renal Physiol 287, F940-F953
 |  Abstract »  |  Full Text »  |  PDF »

Fourier Transform Infrared Spectroscopy on the Rap{middle dot}RapGAP Reaction, GTPase Activation without an Arginine Finger.

P. P. Chakrabarti, Y. Suveyzdis, A. Wittinghofer, and K. Gerwert (2004)
J. Biol. Chem. 279, 46226-46233
 |  Abstract »  |  Full Text »  |  PDF »

cAMP-dependent Protein Kinase Type I Regulates Ethanol-induced cAMP Response Element-mediated Gene Expression via Activation of CREB-binding Protein and Inhibition of MAPK.

A. Constantinescu, M. Wu, O. Asher, and I. Diamond (2004)
J. Biol. Chem. 279, 43321-43329
 |  Abstract »  |  Full Text »  |  PDF »

Locally applied cilostazol suppresses neointimal hyperplasia by inhibiting tenascin-c synthesis and smooth muscle cell proliferation in free artery grafts.

K. Fujinaga, K. Onoda, K. Yamamoto, K. Imanaka-Yoshida, M. Takao, T. Shimono, H. Shimpo, T. Yoshida, and I. Yada (2004)
J. Thorac. Cardiovasc. Surg. 128, 357-363
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Roles for Src Tyrosine Kinase in {beta}2-Adrenergic Receptor Signaling to MAPK and in Receptor Internalization.

J. Huang, Y. Sun, and X.-Y. Huang (2004)
J. Biol. Chem. 279, 21637-21642
 |  Abstract »  |  Full Text »  |  PDF »

Dynamic Changes in C-Raf Phosphorylation and 14-3-3 Protein Binding in Response to Growth Factor Stimulation: DIFFERENTIAL ROLES OF 14-3-3 PROTEIN BINDING SITES.

M. Hekman, S. Wiese, R. Metz, S. Albert, J. Troppmair, J. Nickel, M. Sendtner, and U. R. Rapp (2004)
J. Biol. Chem. 279, 14074-14086
 |  Abstract »  |  Full Text »  |  PDF »

Prostacyclin Induces Apoptosis of Vascular Smooth Muscle Cells by a cAMP-Mediated Inhibition of Extracellular Signal-Regulated Kinase Activity and Can Counteract the Mitogenic Activity of Endothelin-1 or Basic Fibroblast Growth Factor.

R.-c. Li, T. Cindrova-Davies, J. N. Skepper, and L. A. Sellers (2004)
Circ. Res. 94, 759-767
 |  Abstract »  |  Full Text »  |  PDF »

{Delta}Raf-1:ER* Bypasses the Cyclic AMP Block of Extracellular Signal-Regulated Kinase 1 and 2 Activation but Not CDK2 Activation or Cell Cycle Reentry.

K. Balmanno, T. Millar, M. McMahon, and S. J. Cook (2003)
Mol. Cell. Biol. 23, 9303-9317
 |  Abstract »  |  Full Text »  |  PDF »

A Predominant Role for Inhibition of the Adenylate Cyclase/Protein Kinase A Pathway in ERK Activation by Cannabinoid Receptor 1 in N1E-115 Neuroblastoma Cells.

M. I. Davis, J. Ronesi, and D. M. Lovinger (2003)
J. Biol. Chem. 278, 48973-48980
 |  Abstract »  |  Full Text »  |  PDF »

Cyclooxygenase-2-Derived E Prostaglandins Down-Regulate Matrix Metalloproteinase-1 Expression in Fibroblast-Like Synoviocytes via Inhibition of Extracellular Signal-Regulated Kinase Activation.

M. H. Pillinger, P. B. Rosenthal, S. N. Tolani, B. Apsel, V. Dinsell, J. Greenberg, E. S. L. Chan, P. F. Gomez, and S. B. Abramson (2003)
J. Immunol. 171, 6080-6089
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory Role of cAMP on Expression of Cdk4 and p27Kip1 by Inhibiting Phosphatidylinositol 3-kinase in Corneal Endothelial Cells.

H. T. Lee and E. P. Kay (2003)
Invest. Ophthalmol. Vis. Sci. 44, 3816-3825
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase A Blocks Raf-1 Activity by Stimulating 14-3-3 Binding and Blocking Raf-1 Interaction with Ras.

N. Dumaz and R. Marais (2003)
J. Biol. Chem. 278, 29819-29823
 |  Abstract »  |  Full Text »  |  PDF »

Melanin-Concentrating Hormone Receptor 1 Activates Extracellular Signal-Regulated Kinase and Synergizes with Gs-Coupled Pathways.

P. Pissios, D. J. Trombly, I. Tzameli, and E. Maratos-Flier (2003)
Endocrinology 144, 3514-3523
 |  Abstract »  |  Full Text »  |  PDF »

Connective Tissue Growth Factor Gene Regulation. REQUIREMENTS FOR ITS INDUCTION BY TRANSFORMING GROWTH FACTOR-beta 2 IN FIBROBLASTS.

A. Leask, A. Holmes, C. M. Black, and D. J. Abraham (2003)
J. Biol. Chem. 278, 13008-13015
 |  Abstract »  |  Full Text »  |  PDF »

Dual Effect of Pituitary Adenylate Cyclase Activating Polypeptide on Prostate Tumor LNCaP Cells: Short- and Long-Term Exposure Affect Proliferation and Neuroendocrine Differentiation.

D. Farini, A. Puglianiello, C. Mammi, G. Siracusa, and C. Moretti (2003)
Endocrinology 144, 1631-1643
 |  Abstract »  |  Full Text »  |  PDF »

Long-Acting Ca2+ Blockers Prevent Myocardial Remodeling Induced by Chronic NO Inhibition in Rats.

S. Sanada, K. Node, T. Minamino, S. Takashima, A. Ogai, H. Asanuma, H. Ogita, Y. Liao, M. Asakura, J. Kim, et al. (2003)
Hypertension 41, 963-967
 |  Abstract »  |  Full Text »  |  PDF »

cAMP inhibits both Ras and Rap1 activation in primary human T lymphocytes, but only Ras inhibition correlates with blockade of cell cycle progression.

T. Grader-Beck, A. A. F. L. van Puijenbroek, L. M. Nadler, and V. A. Boussiotis (2003)
Blood 101, 998-1006
 |  Abstract »  |  Full Text »  |  PDF »

Ras-dependent ERK Activation by the Human Gs-coupled Serotonin Receptors 5-HT4(b) and 5-HT7(a).

J. H. Norum, K. Hart, and F. O. Levy (2003)
J. Biol. Chem. 278, 3098-3104
 |  Abstract »  |  Full Text »  |  PDF »

Cell Condition-dependent Regulation of ERK5 by cAMP.

G. W. Pearson and M. H. Cobb (2002)
J. Biol. Chem. 277, 48094-48098
 |  Abstract »  |  Full Text »  |  PDF »

cAMP-dependent Protein Kinase and Ca2+ Influx through L-type Voltage-gated Calcium Channels Mediate Raf-independent Activation of Extracellular Regulated Kinase in Response to Glucagon-like Peptide-1 in Pancreatic beta -Cells.

E. Gomez, C. Pritchard, and T. P. Herbert (2002)
J. Biol. Chem. 277, 48146-48151
 |  Abstract »  |  Full Text »  |  PDF »

Direct Binding of the {beta}1 Adrenergic Receptor to the Cyclic AMP-Dependent Guanine Nucleotide Exchange Factor CNrasGEF Leads to Ras Activation.

Y. Pak, N. Pham, and D. Rotin (2002)
Mol. Cell. Biol. 22, 7942-7952
 |  Abstract »  |  Full Text »  |  PDF »

Dancing with Different Partners: Protein Kinase A Phosphorylation of Seven Membrane-Spanning Receptors Regulates Their G Protein-Coupling Specificity.

R. J. Lefkowitz, K. L. Pierce, and L. M. Luttrell (2002)
Mol. Pharmacol. 62, 971-974
 |  Full Text »  |  PDF »

Regulation of the ETS Transcription Factor ER81 by the 90-kDa Ribosomal S6 Kinase 1 and Protein Kinase A.

J. Wu and R. Janknecht (2002)
J. Biol. Chem. 277, 42669-42679
 |  Abstract »  |  Full Text »  |  PDF »

Galpha and Gbeta gamma Require Distinct Src-dependent Pathways to Activate Rap1 and Ras.

J. M. Schmitt and P. J. S. Stork (2002)
J. Biol. Chem. 277, 43024-43032
 |  Abstract »  |  Full Text »  |  PDF »

Effects of epidermal growth factor on epinephrine-stimulated heart function in rodents.

J. Lorita, N. Escalona, S. Faraudo, M. Soley, and I. Ramirez (2002)
Am J Physiol Heart Circ Physiol 283, H1887-H1895
 |  Abstract »  |  Full Text »  |  PDF »

Platelet factor 4 inhibits FGF2-induced endothelial cell proliferation via the extracellular signal-regulated kinase pathway but not by the phosphatidylinositol 3-kinase pathway.

E. Sulpice, M. Bryckaert, J. Lacour, J.-O. Contreres, and G. Tobelem (2002)
Blood 100, 3087-3094
 |  Abstract »  |  Full Text »  |  PDF »

Complement-Induced Impairment of Innate Immunity During Sepsis.

M. S. Huber-Lang, E. M. Younkin, J. V. Sarma, S. R. McGuire, K. T. Lu, R. F. Guo, V. A. Padgaonkar, J. T. Curnutte, R. Erickson, and P. A. Ward (2002)
J. Immunol. 169, 3223-3231
 |  Abstract »  |  Full Text »  |  PDF »

Opening of the adenosine triphosphate-sensitive potassium channel attenuates cardiac remodeling induced by long-term inhibition of nitric oxide synthesis: Role of 70-kDa S6 kinase and extracellular signal-regulated kinase.

S. Sanada, K. Node, H. Asanuma, H. Ogita, S. Takashima, T. Minamino, M. Asakura, Y. Liao, A. Ogai, J. Kim, et al. (2002)
J. Am. Coll. Cardiol. 40, 991-997
 |  Abstract »  |  Full Text »  |  PDF »

Activation and Role of MAP Kinase-Dependent Pathways in Retinal Pigment Epithelial Cells: ERK and RPE Cell Proliferation.

C. Hecquet, G. Lefevre, M. Valtink, K. Engelmann, and F. Mascarelli (2002)
Invest. Ophthalmol. Vis. Sci. 43, 3091-3098
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Steroidogenic Genes by Insulin-Like Growth Factor-1 and Follicle-Stimulating Hormone: Differential Responses of Cytochrome P450 Side-Chain Cleavage, Steroidogenic Acute Regulatory Protein, and 3{beta}-Hydroxysteroid Dehydrogenase/Isomerase in Rat Granulosa Cells.

S. Eimerl and J. Orly (2002)
Biol Reprod 67, 900-910
 |  Abstract »  |  Full Text »  |  PDF »

MAP Kinase Stimulation by cAMP Does Not Require RAP1 but SRC Family Kinases.

M. Klinger, O. Kudlacek, M. G. Seidel, M. Freissmuth, and V. Sexl (2002)
J. Biol. Chem. 277, 32490-32497
 |  Abstract »  |  Full Text »  |  PDF »

The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulates the Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells.

M. J. Cross, L. Lu, P. Magnusson, D. Nyqvist, K. Holmqvist, M. Welsh, and L. Claesson-Welsh (2002)
Mol. Biol. Cell 13, 2881-2893
 |  Abstract »  |  Full Text »  |  PDF »

Vasoprotection by nitric oxide: mechanisms and therapeutic potential.

M. T Gewaltig and G. Kojda (2002)
Cardiovasc Res 55, 250-260
 |  Abstract »  |  Full Text »  |  PDF »

Phagocytosis of Apoptotic Cells by Macrophages Induces Novel Signaling Events Leading to Cytokine-Independent Survival and Inhibition of Proliferation: Activation of Akt and Inhibition of Extracellular Signal-Regulated Kinases 1 and 2.

S. M. Reddy, K.-H. K. Hsiao, V. E. Abernethy, H. Fan, A. Longacre, W. Lieberthal, J. Rauch, J. S. Koh, and J. S. Levine (2002)
J. Immunol. 169, 702-713
 |  Abstract »  |  Full Text »  |  PDF »

Cell Cycle-dependent Subcellular Localization of Exchange Factor Directly Activated by cAMP.

J. Qiao, F. C. Mei, V. L. Popov, L. A. Vergara, and X. Cheng (2002)
J. Biol. Chem. 277, 26581-26586
 |  Abstract »  |  Full Text »  |  PDF »

Cooperation of Protein Kinase A and Ras/ERK Signaling Pathways Is Required for AP-1-mediated Activation of Fibroblast Growth Factor-inducible Response Element (FiRE).

J.-P. Pursiheimo, J. Saari, M. Jalkanen, and M. Salmivirta (2002)
J. Biol. Chem. 277, 25344-25355
 |  Abstract »  |  Full Text »  |  PDF »

Activation and Induction of NUR77/NURR1 in Corticotrophs by CRH/cAMP: Involvement of Calcium, Protein Kinase A, and MAPK Pathways.

D. Kovalovsky, D. Refojo, A. C. Liberman, D. Hochbaum, M. P. Pereda, O. A. Coso, G. K. Stalla, F. Holsboer, and E. Arzt (2002)
Mol. Endocrinol. 16, 1638-1651
 |  Abstract »  |  Full Text »  |  PDF »

New Signaling Pathway for Parathyroid Hormone and Cyclic AMP Action on Extracellular-regulated Kinase and Cell Proliferation in Bone Cells. CHECKPOINT OF MODULATION BY CYCLIC AMP.

T. Fujita, T. Meguro, R. Fukuyama, H. Nakamuta, and M. Koida (2002)
J. Biol. Chem. 277, 22191-22200
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic AMP Blocks Cell Growth through Raf-1-Dependent and Raf-1-Independent Mechanisms.

N. Dumaz, Y. Light, and R. Marais (2002)
Mol. Cell. Biol. 22, 3717-3728
 |  Abstract »  |  Full Text »  |  PDF »

Protein kinase A regulates {beta}2 integrin avidity in neutrophils.

S. L. Jones (2002)
J. Leukoc. Biol. 71, 1042-1048
 |  Abstract »  |  Full Text »  |  PDF »

Hypertonicity increases cAMP in PMN and blocks oxidative burst by PKA-dependent and -independent mechanisms.

T. Orlic, W. H. Loomis, A. Shreve, S. Namiki, and W. G. Junger (2002)
Am J Physiol Cell Physiol 282, C1261-C1269
 |  Abstract »  |  Full Text »  |  PDF »

Mechanotransduction in the Lung: Cyclic stretch activates ERK1/2 via G proteins and EGFR in alveolar epithelial cells.

E. Correa-Meyer, L. Pesce, C. Guerrero, and J. I. Sznajder (2002)
Am J Physiol Lung Cell Mol Physiol 282, L883-L891
 |  Abstract »  |  Full Text »  |  PDF »

Activation of m-Calpain (Calpain II) by Epidermal Growth Factor Is Limited by Protein Kinase A Phosphorylation of m-Calpain.

H. Shiraha, A. Glading, J. Chou, Z. Jia, and A. Wells (2002)
Mol. Cell. Biol. 22, 2716-2727
 |  Abstract »  |  Full Text »  |  PDF »

The Nuclear Receptor Coactivators p300/CBP/Cointegrator-Associated Protein (p/CIP) and Transcription Intermediary Factor 2 (TIF2) Differentially Regulate PKA-Stimulated Transcriptional Activity of Steroidogenic Factor 1.

B. Borud, T. Hoang, M. Bakke, A. L. Jacob, J. Lund, and G. Mellgren (2002)
Mol. Endocrinol. 16, 757-773
 |  Abstract »  |  Full Text »  |  PDF »

Differential Signaling of Cyclic AMP. OPPOSING EFFECTS OF EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CYCLIC AMP AND cAMP-DEPENDENT PROTEIN KINASE ON PROTEIN KINASE B ACTIVATION.

F. C. Mei, J. Qiao, O. M. Tsygankova, J. L. Meinkoth, L. A. Quilliam, and X. Cheng (2002)
J. Biol. Chem. 277, 11497-11504
 |  Abstract »  |  Full Text »  |  PDF »

ERK Activation by G-protein-coupled Receptors in Mouse Brain Is Receptor Identity-specific.

A. M. Vanhoose, M. Emery, L. Jimenez, and D. G. Winder (2002)
J. Biol. Chem. 277, 9049-9053
 |  Abstract »  |  Full Text »  |  PDF »

Neuropeptide Y modifies the hypertrophic response of adult ventricular cardiomyocytes to norepinephrine.

M. Kanevskij, G. Taimor, M. Schafer, H. M. Piper, and K.-D. Schluter (2002)
Cardiovasc Res 53, 879-887
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Action Via the G Protein-Coupled Receptor, GPR30: Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis.

E. J. Filardo, J. A. Quinn, A. R. Frackelton Jr., and K. I. Bland (2002)
Mol. Endocrinol. 16, 70-84
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic AMP Raises Intracellular Ca2+ in Human Megakaryocytes Independent of Protein Kinase A.

E. den Dekker, J. W.M. Heemskerk, G. Gorter, H. van der Vuurst, J. Donath, C. Kroner, K. Mikoshiba, and J.-W. N. Akkerman (2002)
Arterioscler Thromb Vasc Biol 22, 179-186
 |  Abstract »  |  Full Text »  |  PDF »

Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide.

C. Berry, R. Touyz, A. F. Dominiczak, R. C. Webb, and D. G. Johns (2001)
Am J Physiol Heart Circ Physiol 281, H2337-H2365
 |  Abstract »  |  Full Text »  |  PDF »

Beraprost sodium regulates cell cycle in vascular smooth muscle cells through cAMP signaling by preventing down-regulation of p27Kip1.

M. Ii, M. Hoshiga, R. Fukui, N. Negoro, T. Nakakoji, F. Nishiguchi, E. Kohbayashi, T. Ishihara, and T. Hanafusa (2001)
Cardiovasc Res 52, 500-508
 |  Abstract »  |  Full Text »  |  PDF »

Drosophila-Raf Acts to Elaborate Dorsoventral Pattern in the Ectoderm of Developing Embryos.

K. Radke, K. Johnson, R. Guo, A. Davidson, and L. Ambrosio (2001)
Genetics 159, 1031-1044
 |  Abstract »  |  Full Text »  |  PDF »

Follicle-stimulating Hormone Stimulates Protein Kinase A-mediated Histone H3 Phosphorylation and Acetylation Leading to Select Gene Activation in Ovarian Granulosa Cells.

L. M. Salvador, Y. Park, J. Cottom, E. T. Maizels, J. C. R. Jones, R. V. Schillace, D. W. Carr, P. Cheung, C. D. Allis, J. L. Jameson, et al. (2001)
J. Biol. Chem. 276, 40146-40155
 |  Abstract »  |  Full Text »  |  PDF »

Differential Subcellular Actions of ACE Inhibitors and AT1 Receptor Antagonists on Cardiac Remodeling Induced by Chronic Inhibition of NO Synthesis in Rats.

S. Sanada, M. Kitakaze, K. Node, S. Takashima, A. Ogai, H. Asanuma, Y. Sakata, M. Asakura, H. Ogita, Y. Liao, et al. (2001)
Hypertension 38, 404-411
 |  Abstract »  |  Full Text »  |  PDF »

Proliferation, Migration, and ERK Activation in Human Retinal Endothelial Cells through A2B Adenosine Receptor Stimulation.

M. B. Grant, M. I. Davis, S. Caballero, I. Feoktistov, I. Biaggioni, and L. Belardinelli (2001)
Invest. Ophthalmol. Vis. Sci. 42, 2068-2073
 |  Abstract »  |  Full Text »  |  PDF »

Signaling by eNOS through a superoxide-dependent p42/44 mitogen-activated protein kinase pathway.

W. Wang, S. Wang, E. V. Nishanian, A. Del Pilar Cintron, R. A. Wesley, and R. L. Danner (2001)
Am J Physiol Cell Physiol 281, C544-C554
 |  Abstract »  |  Full Text »  |  PDF »

Platelet-Derived Growth Factor Stimulates Phospholipase C-{gamma}1, Extracellular Signal-Regulated Kinase, and Arachidonic Acid Release in Rat Myometrial Cells: Contribution to Cyclic 3',5'-Adenosine Monophosphate Production and Effect on Cell Proliferation.

I. Boulven, B. Palmier, P. Robin, M. Vacher, S. Harbon, and D. Leiber (2001)
Biol Reprod 65, 496-506
 |  Abstract »  |  Full Text »  |  PDF »

Dopamine regulates Na-K-ATPase in alveolar epithelial cells via MAPK-ERK-dependent mechanisms.

C. Guerrero, E. Lecuona, L. Pesce, K. M. Ridge, and J. I. Sznajder (2001)
Am J Physiol Lung Cell Mol Physiol 281, L79-L85
 |  Abstract »  |  Full Text »  |  PDF »

LDL-Activated p38 in Endothelial Cells Is Mediated by Ras.

Y. Zhu, H. Liao, N. Wang, K.-S. Ma, L. K. Verna, J. Y.-J. Shyy, S. Chien, and M. B. Stemerman (2001)
Arterioscler Thromb Vasc Biol 21, 1159-1164
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic AMP-Mediated Inhibition of Cell Growth Requires the Small G Protein Rap1.

J. M. Schmitt and P. J. S. Stork (2001)
Mol. Cell. Biol. 21, 3671-3683
 |  Abstract »  |  Full Text »

Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement.

F. Liu, A. D. Verin, T. Borbiev, and J. G. N. Garcia (2001)
Am J Physiol Lung Cell Mol Physiol 280, L1309-L1317
 |  Abstract »  |  Full Text »  |  PDF »

A Retroviral-Derived Immunosuppressive Peptide Activates Mitogen-Activated Protein Kinases.

A. Takahashi, N. K. Day, V. Luangwedchakarn, R. A. Good, and S. Haraguchi (2001)
J. Immunol. 166, 6771-6775
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the Cooh-Terminal Src Kinase (Csk) by Camp-Dependent Protein Kinase Inhibits Signaling through the T Cell Receptor.

T. Vang, K. M. Torgersen, V. Sundvold, M. Saxena, F. O. Levy, B. S. Skalhegg, V. Hansson, T. Mustelin, and K. Tasken (2001)
J. Exp. Med. 193, 497-508
 |  Abstract »  |  Full Text »  |  PDF »

Schwann Cell Proliferative Responses to cAMP and Nf1 Are Mediated by Cyclin D1.

H. A. Kim, N. Ratner, T. M. Roberts, and C. D. Stiles (2001)
J. Neurosci. 21, 1110-1116
 |  Abstract »  |  Full Text »  |  PDF »

Hormone-Induced Receptor Gene Splicing: Enhanced Expression of the Growth Factor Type I Follicle-Stimulating Hormone Receptor Motif in the Developing Mouse Ovary as a New Paradigm in Growth Regulation.

P. S. Babu, N. Danilovich, and M. R. Sairam (2001)
Endocrinology 142, 381-389
 |  Abstract »  |  Full Text »  |  PDF »

8-Bromo-Cyclic AMP Induces Phosphorylation of Two Sites in SRC-1 That Facilitate Ligand-Independent Activation of the Chicken Progesterone Receptor and Are Critical for Functional Cooperation between SRC-1 and CREB Binding Protein.

B. G. Rowan, N. Garrison, N. L. Weigel, and B. W. O'Malley (2000)
Mol. Cell. Biol. 20, 8720-8730
 |  Abstract »  |  Full Text »

Adrenergic Regulation of Mitogen-Activated Protein Kinase in Rat Pinealocytes: Opposing Effects of Protein Kinase A and Protein Kinase G.

A. K. Ho and C. L. Chik (2000)
Endocrinology 141, 4496-4502
 |  Abstract »  |  Full Text »  |  PDF »

Signal Transduction Mechanisms Mediating the Physiological and Pathophysiological Actions of Angiotensin II in Vascular Smooth Muscle Cells.

R. M. Touyz and E. L. Schiffrin (2000)
Pharmacol. Rev. 52, 639-672
 |  Abstract »  |  Full Text »  |  PDF »

CD28 and the Tyrosine Kinase Lck Stimulate Mitogen-Activated Protein Kinase Activity in T Cells via Inhibition of the Small G Protein Rap1.

K. D. Carey, T. J. Dillon, J. M. Schmitt, A. M. Baird, A. D. Holdorf, D. B. Straus, A. S. Shaw, and P. J. S. Stork (2000)
Mol. Cell. Biol. 20, 8409-8419
 |  Abstract »  |  Full Text »

c-Src Signaling Induced by the Adapters Sin and Cas Is Mediated by Rap1 GTPase.

L. Xing, C. Ge, R. Zeltser, G. Maskevitch, B. J. Mayer, and K. Alexandropoulos (2000)
Mol. Cell. Biol. 20, 7363-7377
 |  Abstract »  |  Full Text »

Cell-Type Specific Integration of Cross-Talk between Extracellular Signal-Regulated Kinase and cAMP Signaling.

M. D. Houslay and W. Kolch (2000)
Mol. Pharmacol. 58, 659-668
 |  Full Text »

Elevation of Intracellular cAMP Inhibits Growth Factor-Mediated Matrix Metalloproteinase-9 Induction and Keratinocyte Migration.

L. J. McCawley, S. Li, M. Benavidez, J. Halbleib, E. V. Wattenberg, and L. G. Hudson (2000)
Mol. Pharmacol. 58, 145-151
 |  Abstract »  |  Full Text »

Loss of Rhb1, a Rheb-Related GTPase in Fission Yeast, Causes Growth Arrest With a Terminal Phenotype Similar to That Caused by Nitrogen Starvation.

K. E. Mach, K. A. Furge, and C. F. Albright (2000)
Genetics 155, 611-622
 |  Abstract »  |  Full Text »

To Advertise   |   Find Products