Science 5 November 1993: Vol. 262. no. 5135, pp. 905 - 907 DOI: 10.1126/science.7694361

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Articles

Regulation of Thymic NKT Cell Development by the B7-CD28 Costimulatory Pathway.

J. A. Williams, J. M. Lumsden, X. Yu, L. Feigenbaum, J. Zhang, S. M. Steinberg, and R. J. Hodes (2008)
J. Immunol. 181, 907-917
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Antitumor Immune Response by Homeostatic Proliferation and CD28 Signaling.

T. Suzuki, S. Ogawa, K. Tanabe, H. Tahara, R. Abe, and H. Kishimoto (2008)
J. Immunol. 180, 4596-4605
 |  Abstract »  |  Full Text »  |  PDF »

B7 Costimulation Molecules Expressed from the Herpes Simplex Virus 2 Genome Rescue Immune Induction in B7-Deficient Mice.

L. G. Thebeau, S. P. Vagvala, Y. M. Wong, and L. A. Morrison (2007)
J. Virol. 81, 12200-12209
 |  Abstract »  |  Full Text »  |  PDF »

CD86 Regulates IgG1 Production via a CD19-Dependent Mechanism.

N. W. Kin and V. M. Sanders (2007)
J. Immunol. 179, 1516-1523
 |  Abstract »  |  Full Text »  |  PDF »

Immunologic Approaches to Ovarian Cancer Treatment.

P. Sabbatini and K. Odunsi (2007)
J. Clin. Oncol. 25, 2884-2893
 |  Abstract »  |  Full Text »  |  PDF »

Direct CD28 Costimulation Is Required for CD8+ T Cell-Mediated Resistance to an Acute Viral Disease in a Natural Host.

M. Fang and L. J. Sigal (2006)
J. Immunol. 177, 8027-8036
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory Lung Secretions Inhibit Dendritic Cell Maturation and Function via Neutrophil Elastase.

A. Roghanian, E. M. Drost, W. MacNee, S. E. M. Howie, and J.-M. Sallenave (2006)
Am. J. Respir. Crit. Care Med. 174, 1189-1198
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ T Cell Expressed CD80 Regulates Central Nervous System Effector Function and Survival during Experimental Autoimmune Encephalomyelitis..

J. R. Podojil, A. P. Kohm, and S. D. Miller (2006)
J. Immunol. 177, 2948-2958
 |  Abstract »  |  Full Text »  |  PDF »

CD86 Stimulation on a B Cell Activates the Phosphatidylinositol 3-Kinase/Akt and Phospholipase C{gamma}2/Protein Kinase C{alpha}beta Signaling Pathways..

N. W. Kin and V. M. Sanders (2006)
J. Immunol. 176, 6727-6735
 |  Abstract »  |  Full Text »  |  PDF »

CTLA-4 Blockade: Autoimmunity As Treatment.

D. Kapadia and L. Fong (2005)
J. Clin. Oncol. 23, 8926-8928
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Regulated Costimulation in the Thymus Is Critical for T Cell Development: Dysregulated CD28 Costimulation Can Bypass the Pre-TCR Checkpoint.

J. A. Williams, K. S. Hathcock, D. Klug, Y. Harada, B. Choudhury, J. P. Allison, R. Abe, and R. J. Hodes (2005)
J. Immunol. 175, 4199-4207
 |  Abstract »  |  Full Text »  |  PDF »

Differential subcellular localization of CD86 in human PBMC-derived macrophages and DCs, and ultrastructural characterization by immuno-electron microscopy.

C. M. Smyth, G. Logan, R. Boadle, P. B. Rowe, J. A. Smythe, and I. E. Alexander (2005)
Int. Immunol. 17, 123-132
 |  Abstract »  |  Full Text »  |  PDF »

B7-CD28 Interaction Promotes Proliferation and Survival but Suppresses Differentiation of CD4-CD8- T Cells in the Thymus.

X. Zheng, J.-X. Gao, X. Chang, Y. Wang, Y. Liu, J. Wen, H. Zhang, J. Zhang, Y. Liu, and P. Zheng (2004)
J. Immunol. 173, 2253-2261
 |  Abstract »  |  Full Text »  |  PDF »

MHC class II-independent and -dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA-4).

W. Stohl, D. Xu, K. S. Kim, C. S. David, and J. P. Allison (2004)
Int. Immunol. 16, 895-904
 |  Abstract »  |  Full Text »  |  PDF »

CD86 and {beta}2-Adrenergic Receptor Signaling Pathways, Respectively, Increase Oct-2 and OCA-B Expression and Binding to the 3'-IgH Enhancer in B Cells.

J. R. Podojil, N. W. Kin, and V. M. Sanders (2004)
J. Biol. Chem. 279, 23394-23404
 |  Abstract »  |  Full Text »  |  PDF »

Neural Stem/Progenitor Cells Express Costimulatory Molecules That Are Differentially Regulated by Inflammatory and Apoptotic Stimuli.

J. Imitola, M. Comabella, A. K. Chandraker, F. Dangond, M. H. Sayegh, E. Y. Snyder, and S. J. Khoury (2004)
Am. J. Pathol. 164, 1615-1625
 |  Abstract »  |  Full Text »  |  PDF »

Selective Regulation of Mature IgG1 Transcription by CD86 and {beta}2-Adrenergic Receptor Stimulation.

J. R. Podojil and V. M. Sanders (2003)
J. Immunol. 170, 5143-5151
 |  Abstract »  |  Full Text »  |  PDF »

Differential Requirements for Expression of CD80/86 and CD40 on B Cells for T-Dependent Antibody Responses In Vivo.

J. M. Lumsden, J. A. Williams, and R. J. Hodes (2003)
J. Immunol. 170, 781-787
 |  Abstract »  |  Full Text »  |  PDF »

4-1BB (CD137) Differentially Regulates Murine In Vivo Protein- and Polysaccharide-Specific Immunoglobulin Isotype Responses to Streptococcus pneumoniae.

Z.-Q. Wu, A. Q. Khan, Y. Shen, K. M. Wolcott, W. Dawicki, T. H. Watts, R. S. Mittler, and C. M. Snapper (2003)
Infect. Immun. 71, 196-204
 |  Abstract »  |  Full Text »  |  PDF »

Cancer Vaccines.

I. Espinoza-Delgado (2002)
Oncologist 7, 20-33
 |  Abstract »  |  Full Text »  |  PDF »

Role of CD28 co-stimulation in generation and maintenance of virus-specific T cells.

J. E. Christensen, J. P. Christensen, N. N. Kristensen, N. J. V. Hansen, A. Stryhn, and A. R. Thomsen (2002)
Int. Immunol. 14, 701-711
 |  Abstract »  |  Full Text »  |  PDF »

4-1BB Ligand-Mediated Costimulation of Human T Cells Induces CD4 and CD8 T Cell Expansion, Cytokine Production, and the Development of Cytolytic Effector Function.

T. Wen, J. Bukczynski, and T. H. Watts (2002)
J. Immunol. 168, 4897-4906
 |  Abstract »  |  Full Text »  |  PDF »

B7-CTLA4 interaction promotes cognate destruction of tumor cells by cytotoxic T lymphocytes in vivo.

X.-F. Bai, J. Liu, K. F. May Jr, Y. Guo, P. Zheng, and Y. Liu (2002)
Blood 99, 2880-2889
 |  Abstract »  |  Full Text »  |  PDF »

Opposing Effects of Anti-Activation-Inducible Lymphocyte- Immunomodulatory Molecule/Inducible Costimulator Antibody on the Development of Acute Versus Chronic Graft-Versus-Host Disease.

S.-h. Ogawa, G. Nagamatsu, M. Watanabe, S. Watanabe, T. Hayashi, S. Horita, K. Nitta, H. Nihei, K. Tezuka, and R. Abe (2001)
J. Immunol. 167, 5741-5748
 |  Abstract »  |  Full Text »  |  PDF »

B7H Costimulates Clonal Expansion of, and Cognate Destruction of Tumor Cells by, CD8+ T Lymphocytes In Vivo.

X. Liu, X.-F. Bai, J. Wen, J.-X. Gao, J. Liu, P. Lu, Y. Wang, P. Zheng, and Y. Liu (2001)
J. Exp. Med. 194, 1339-1348
 |  Abstract »  |  Full Text »  |  PDF »

Impairment in the Expression and Activity of Fyn During Differentiation of Naive CD4+ T Cells into the Th2 Subset.

T. Tamura, O. Igarashi, A. Hino, H. Yamane, S. Aizawa, T. Kato, and H. Nariuchi (2001)
J. Immunol. 167, 1962-1969
 |  Abstract »  |  Full Text »  |  PDF »

B7 Interactions with CD28 and CTLA-4 Control Tolerance or Induction of Mucosal Inflammation in Chronic Experimental Colitis.

Z. Liu, K. Geboes, P. Hellings, P. Maerten, H. Heremans, P. Vandenberghe, L. Boon, P. van Kooten, P. Rutgeerts, and J. L. Ceuppens (2001)
J. Immunol. 167, 1830-1838
 |  Abstract »  |  Full Text »  |  PDF »

CD28 Signaling Augments Elk-1-Dependent Transcription at the c-fos Gene During Antigen Stimulation.

W. Li, C. D. Whaley, J. L. Bonnevier, A. Mondino, M. E. Martin, K. M. Aagaard-Tillery, and D. L. Mueller (2001)
J. Immunol. 167, 827-835
 |  Abstract »  |  Full Text »  |  PDF »

Anti-Sm B Cell Differentiation in Ig Transgenic MRL/Mp-lpr/lpr Mice: Altered Differentiation and an Accelerated Response.

S. Santulli-Marotto, Y. Qian, S. Ferguson, and S. H. Clarke (2001)
J. Immunol. 166, 5292-5299
 |  Abstract »  |  Full Text »  |  PDF »

Viral IL-10-Induced Immunosuppression Requires Th2 Cytokines and Impairs APC Function Within the Allograft.

L. Qin, Y. Ding, H. Tahara, and J. S. Bromberg (2001)
J. Immunol. 166, 2385-2393
 |  Abstract »  |  Full Text »  |  PDF »

Acquisition of CD80 (B7-1) by T Cells.

H. Sabzevari, J. Kantor, A. Jaigirdar, Y. Tagaya, M. Naramura, J. W. Hodge, J. Bernon, and J. Schlom (2001)
J. Immunol. 166, 2505-2513
 |  Abstract »  |  Full Text »  |  PDF »

Soluble CD14 enriched in colostrum and milk induces B cell growth and differentiation.

D. Filipp, K. Alizadeh-Khiavi, C. Richardson, A. Palma, N. Paredes, O. Takeuchi, S. Akira, and M. Julius (2001)
PNAS 98, 603-608
 |  Abstract »  |  Full Text »  |  PDF »

B7 Requirements for Primary and Secondary Protein- and Polysaccharide-Specific Ig Isotype Responses to Streptococcus pneumoniae.

Z.-Q. Wu, A. Q. Khan, Y. Shen, J. Schartman, R. Peach, A. Lees, J. J. Mond, W. C. Gause, and C. M. Snapper (2000)
J. Immunol. 165, 6840-6848
 |  Abstract »  |  Full Text »  |  PDF »

Salmonella enterica Serovar Typhimurium-Induced Maturation of Bone Marrow-Derived Dendritic Cells.

M. Svensson, C. Johansson, and M. J. Wick (2000)
Infect. Immun. 68, 6311-6320
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of Costimulation Through B7/CD28 Inhibits Experimental Autoimmune Uveoretinitis, But Does Not Induce Long-Term Tolerance.

P. B. Silver, K. S. Hathcock, C.-C. Chan, B. Wiggert, and R. R. Caspi (2000)
J. Immunol. 165, 5041-5047
 |  Abstract »  |  Full Text »  |  PDF »

Construction and Characterization of Bispecific Costimulatory Molecules Containing a Minimized CD86 (B7-2) Domain and Single-Chain Antibody Fragments for Tumor Targeting.

F. Rohrbach, B. Gerstmayer, M. Biburger, and W. Wels (2000)
Clin. Cancer Res. 6, 4314-4322
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of the B Cell Receptor, CD86 (B7-2), and the {beta}2-Adrenergic Receptor Intrinsically Modulates the Level of IgG1 and IgE Produced per B Cell.

D. J. Kasprowicz, A. P. Kohm, M. T. Berton, A. J. Chruscinski, A. Sharpe, and V. M. Sanders (2000)
J. Immunol. 165, 680-690
 |  Abstract »  |  Full Text »  |  PDF »

Immunohistowax processing, a new fixation and embedding method for light microscopy, which preserves antigen immunoreactivity and morphological structures: visualisation of dendritic cells in peripheral organs.

B. Pajak, T. De Smedt, V. Moulin, C. De Trez, R. Maldonado-Lopez, G. Vansanten, E. Briend, J. Urbain, O. Leo, and M. Moser (2000)
J. Clin. Pathol. 53, 518-524
 |  Abstract »  |  Full Text »  |  PDF »

The Role of B7 Costimulation in CD4/CD8 T Cell Homeostasis.

X. Yu, S. Fournier, J. P. Allison, A. H. Sharpe, and R. J. Hodes (2000)
J. Immunol. 164, 3543-3553
 |  Abstract »  |  Full Text »  |  PDF »

Naive CD8+ T Cells Do Not Require Costimulation for Proliferation and Differentiation into Cytotoxic Effector Cells.

B. Wang, R. Maile, R. Greenwood, E. J. Collins, and J. A. Frelinger (2000)
J. Immunol. 164, 1216-1222
 |  Abstract »  |  Full Text »  |  PDF »

Danger and OX40 Receptor Signaling Synergize to Enhance Memory T Cell Survival by Inhibiting Peripheral Deletion.

J. R. Maxwell, A. Weinberg, R. A. Prell, and A. T. Vella (2000)
J. Immunol. 164, 107-112
 |  Abstract »  |  Full Text »  |  PDF »

A Critical Role for B7/CD28 Costimulation in Experimental Autoimmune Encephalomyelitis: A Comparative Study Using Costimulatory Molecule-Deficient Mice and Monoclonal Antibody Blockade.

A. M. Girvin, M. C. Dal Canto, L. Rhee, B. Salomon, A. Sharpe, J. A. Bluestone, and S. D. Miller (2000)
J. Immunol. 164, 136-143
 |  Abstract »  |  Full Text »  |  PDF »

Differential Requirements for NF-{kappa}B and AP-1 trans-Activation in Response to Minimal TCR Engagement by a Partial Agonist in Naive CD8 T Cells.

N. Auphan, S. Ghosh, R. A. Flavell, and A.-M. Schmitt-Verhulst (1999)
J. Immunol. 163, 5219-5227
 |  Abstract »  |  Full Text »  |  PDF »

Strong Cytotoxic T Lymphocyte Responses to a Macrophage Inflammatory Protein 1{{alpha}}-expressing Tumor: Linkage between Inflammation and Specific Immunity.

M. Maric and Y. Liu (1999)
Cancer Res. 59, 5549-5553
 |  Abstract »  |  Full Text »  |  PDF »

CD28 Interactions with Either CD80 or CD86 Are Sufficient to Induce Allergic Airway Inflammation in Mice.

M. Mathur, K. Herrmann, Y. Qin, F. Gulmen, X. Li, R. Krimins, J. Weinstock, D. Elliott, J. A. Bluestone, and P. Padrid (1999)
Am. J. Respir. Cell Mol. Biol. 21, 498-509
 |  Abstract »  |  Full Text »

Cutting Edge: Thymic Selection and Autoreactivity Are Regulated by Multiple Coreceptors Involved in T Cell Activation.

D. M. Page (1999)
J. Immunol. 163, 3577-3581
 |  Abstract »  |  Full Text »  |  PDF »

Differential Coupling of Second Signals for Cytotoxicity and Proliferation in CD8+ T Cell Effectors: Amplification of the Lytic Potential by B7.

M. F. Krummel, W. R. Heath, and J. Allison (1999)
J. Immunol. 163, 2999-3006
 |  Abstract »  |  Full Text »  |  PDF »

Human Fibroblasts Transduced with CD80 or CD86 Efficiently trans-Costimulate CD4+ and CD8+ T Lymphocytes in HLA-Restricted Reactions: Implications for Immune Augmentation Cancer Therapy and Autoimmunity.

J. A. Smythe, P. D. Fink, G. J. Logan, J. Lees, P. B. Rowe, and I. E. Alexander (1999)
J. Immunol. 163, 3239-3249
 |  Abstract »  |  Full Text »  |  PDF »

CD28, IL-2-Independent Costimulatory Pathways for CD8 T Lymphocyte Activation.

H. Sepulveda, A. Cerwenka, T. Morgan, and R. W. Dutton (1999)
J. Immunol. 163, 1133-1142
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Autoimmunity in Ig Transgenic Mice.

S. Shinde, R. Gee, S. Santulli-Marotto, L. K. Bockenstedt, S. H. Clarke, and M. J. Mamula (1999)
J. Immunol. 162, 7519-7524
 |  Abstract »  |  Full Text »  |  PDF »

Vaccine therapy for cancer—fact or fiction?.

T.R.J. Evans and S.B. Kaye (1999)
QJM 92, 299-307
 |  Full Text »  |  PDF »

The A-G polymorphism in exon 1 of the CTLA-4 gene is not associated with systemic lupus erythematosus.

J. Heward, C. Gordon, A. Allahabadia, A. H Barnett, J. A Franklyn, and S. C L Gough (1999)
Ann Rheum Dis 58, 193-195
 |  Abstract »  |  Full Text »

CD40 Activation Boosts T Cell Immunity In Vivo by Enhancing T Cell Clonal Expansion and Delaying Peripheral T Cell Deletion.

J. R. Maxwell, J. D. Campbell, C. H. Kim, and A. T. Vella (1999)
J. Immunol. 162, 2024-2034
 |  Abstract »  |  Full Text »  |  PDF »

MHC Class II-Dependent NK1.1+ {gamma}{delta} T Cells Are Induced in Mice by Salmonella Infection.

H. Nishimura, J. Washizu, Y. Naiki, T. Hara, Y. Fukui, T. Sasazuki, and Y. Yoshikai (1999)
J. Immunol. 162, 1573-1581
 |  Abstract »  |  Full Text »  |  PDF »

B7.2 Has Opposing Roles During the Activation Versus Effector Stages of Experimental Autoimmune Thyroiditis.

K. E. Peterson, G. C. Sharp, H. Tang, and H. Braley-Mullen (1999)
J. Immunol. 162, 1859-1867
 |  Abstract »  |  Full Text »  |  PDF »

Costimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4+CD8+ thymocytes.

D. Amsen, C. R. Calvo, B. A. Osborne, and A. M. Kruisbeek (1999)
PNAS 96, 622-627
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Immunologic Tolerance for Transplantation.

A. A. ROSSINI, D. L. GREINER, and J. P. MORDES (1999)
Physiol Rev 79, 99-141
 |  Abstract »  |  Full Text »  |  PDF »

The Role of the CD40 Pathway in Alloantigen-Induced Hyporesponsiveness In Vivo.

M. Niimi, T. C. Pearson, C. P. Larsen, D. Z. Alexander, D. Hollenbaugh, A. Aruffo, P. S. Linsley, E. Thomas, K. Campbell, W. C. Fanslow, et al. (1998)
J. Immunol. 161, 5331-5337
 |  Abstract »  |  Full Text »  |  PDF »

Murine Dendritic Cells Pulsed In Vitro with Toxoplasma gondii Antigens Induce Protective Immunity In Vivo.

I. Bourguin, M. Moser, D. Buzoni-Gatel, F. Tielemans, D. Bout, J. Urbain, and O. Leo (1998)
Infect. Immun. 66, 4867-4874
 |  Abstract »  |  Full Text »  |  PDF »

The Role of B7-1 and B7-2 Costimulation for the Generation of CTL Responses In Vivo.

L. J. Sigal, H. Reiser, and K. L. Rock (1998)
J. Immunol. 161, 2740-2745
 |  Abstract »  |  Full Text »  |  PDF »

Preactivation of B Lymphocytes Does Not Enhance Mouse Mammary Tumor Virus Infection.

D. Finke, L. Mortezavi, and H. Acha-Orbea (1998)
J. Virol. 72, 7688-7691
 |  Abstract »  |  Full Text »  |  PDF »

Autoimmunity Without Diabetes in Transgenic Mice Expressing {beta} Cell-Specific CD86, But Not CD80: Parameters that Trigger Progression to Diabetes.

S. Guerder, E. E. Eynon, and R. A. Flavell (1998)
J. Immunol. 161, 2128-2140
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Costimulatory Molecule CD40 in Murine Heart With Acute Myocarditis and Reduction of Inflammation by Treatment With Anti-CD40L/B7-1 Monoclonal Antibodies.

Y. Seko, N. Takahashi, M. Azuma, H. Yagita, K. Okumura, and Y. Yazaki (1998)
Circ. Res. 83, 463-469
 |  Abstract »  |  Full Text »  |  PDF »

Tissue-Specific Up-Regulation of B7-1 Expression and Function During the Course of Murine Relapsing Experimental Autoimmune Encephalomyelitis.

N. J. Karandikar, C. L. Vanderlugt, T. Eagar, L. Tan, J. A. Bluestone, and S. D. Miller (1998)
J. Immunol. 161, 192-199
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Antigen-Dependent Regulation of Telomerase Activity in Murine T Cells.

K. S. Hathcock, N.-p. Weng, R. Merica, M. K. Jenkins, and R. Hodes (1998)
J. Immunol. 160, 5702-5706
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Dynamic Intracellular Reservoir of CD86 Protein in Peripheral Blood Monocytes That Is Not Associated with the Golgi Complex.

C. Smyth, G. Logan, R. P. Weinberger, P. B. Rowe, I. E. Alexander, and J. A. Smythe (1998)
J. Immunol. 160, 5390-5396
 |  Abstract »  |  Full Text »  |  PDF »

B7-CTLA4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor challenge.

P. Zheng, Y. Wu, Y. Guo, C. Lee, and Y. Liu (1998)
PNAS 95, 6284-6289
 |  Abstract »  |  Full Text »  |  PDF »

Purified MHC Class I and Peptide Complexes Activate Naive CD8+ T Cells Independently of the CD28/B7 and LFA-1/ICAM-1 Costimulatory Interactions.

J. S. Goldstein, T. Chen, M. Brunswick, H. Mostowsky, and S. Kozlowski (1998)
J. Immunol. 160, 3180-3187
 |  Abstract »  |  Full Text »  |  PDF »

Effects of In Vivo Administration of Anti–B7-1/B7-2 Monoclonal Antibodies on Murine Acute Myocarditis Caused by Coxsackievirus B3.

Y. Seko, N. Takahashi, M. Azuma, H. Yagita, K. Okumura, and Y. Yazaki (1998)
Circ. Res. 82, 613-618
 |  Abstract »  |  Full Text »  |  PDF »

IL-12 Receptor (IL-12R) Expression and Accumulation of IL-12R{beta}1 and IL-12R{beta}2 mRNAs in CD4+ T Cells by Costimulation with B7-2 Molecules.

O. Igarashi, H. Yamane, S. Imajoh-Ohmi, and H. Nariuchi (1998)
J. Immunol. 160, 1638-1646
 |  Abstract »  |  Full Text »  |  PDF »

Role of CD80 (B7.1) and CD86 (B7.2) in the Immune Response to an Intracellular Pathogen.

C. S. Subauste, R. de Waal Malefyt, and F. Fuh (1998)
J. Immunol. 160, 1831-1840
 |  Abstract »  |  Full Text »  |  PDF »

Development of Murine Allergic Asthma Is Dependent Upon B7-2 Costimulation.

A. M. Keane-Myers, W. C. Gause, F. D. Finkelman, X.-d. Xhou, and M. Wills-Karp (1998)
J. Immunol. 160, 1036-1043
 |  Abstract »  |  Full Text »  |  PDF »

Costimulation through B7-2 (CD86) Is Required for the Induction of a Lung Mucosal T Helper Cell 2 (TH2) Immune Response and Altered Airway Responsiveness.

S. Tsuyuki, J. Tsuyuki, K. Einsle, M. Kopf, and A. J. Coyle (1997)
J. Exp. Med. 185, 1671-1680
 |  Abstract »  |  Full Text »  |  PDF »

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver.

M. A. Kay, L. Meuse, A. M. Gown, P. Linsley, D. Hollenbaugh, A. Aruffo, H. D. Ochs, and C. B. Wilson (1997)
PNAS 94, 4686-4691
 |  Abstract »  |  Full Text »  |  PDF »

CD80 (B7-1) Binds Both CD28 and CTLA-4 with a Low Affinity and Very Fast Kinetics.

P.  A. van der Merwe, D. L. Bodian, S. Daenke, P. Linsley, and S. J. Davis (1997)
J. Exp. Med. 185, 393-404
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Costimulatory Molecules Are Required for the Induction of Effector and Memory Cytotoxic T Lymphocytes.

Y. Liu, R. H. Wenger, M. Zhao, and P. J. Nielsen (1997)
J. Exp. Med. 185, 251-262
 |  Abstract »  |  Full Text »  |  PDF »

CD80 Costimulation Is Essential for the Induction of Airway Eosinophilia.

N. Harris, R. Peach, J. Naemura, P. S. Linsley, G. Le Gros, and F. Ronchese (1997)
J. Exp. Med. 185, 177-182
 |  Abstract »  |  Full Text »  |  PDF »

Costimulatory B7 Molecules in the Pathogenesis of Infectious and Autoimmune Diseases.

H. Reiser and M. J. Stadecker (1996)
N. Engl. J. Med. 335, 1369-1377
 |  Full Text »  |  PDF »

Transcriptional Regulation of the Interleukin-2 Gene in Normal Human Peripheral Blood T Cells.

C. C. W. Hughes and J. S. Pober (1996)
J. Biol. Chem. 271, 5369-5377
 |  Abstract »  |  Full Text »  |  PDF »

Long-term expression of human growth hormone (hGH) in mice containing allogeneic yolk sac cell derived neovascular implants expressing hGH.

Y Wei, J Li, and T. Wagner (1996)
Stem Cells 14, 232-238
 |  Abstract »

Signal Transduction by CD28 Costimulatory Receptor on T Cells.

J. A. Nunès, A. Truneh, D. Olive, and D. A. Cantrell (1996)
J. Biol. Chem. 271, 1591-1598
 |  Abstract »  |  Full Text »  |  PDF »

Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4.

P. Waterhouse, J. M. Penninger, E. Timms, A. Wakeham, A. Shahinian, K. P. Lee, C. B. Thompson, H. Griesser, and T. W. Mak (1995)
Science 270, 985-988
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Characterization of Novel Costimulatory Molecules.

D. S. Vinay, M. Raje, R. K. Verma, and G. C. Mishra (1995)
J. Biol. Chem. 270, 23429-23436
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Treatment of murine lupus with CTLA4Ig.

B. Finck, P. Linsley, and D Wofsy (1994)
Science 265, 1225-1227
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New protein steals the show as 'costimulator' of T cells.

J Cohen (1993)
Science 262, 844-845
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Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice.

G. Freeman, F Borriello, R. Hodes, H Reiser, K. Hathcock, G Laszlo, A. McKnight, J Kim, L Du, D. Lombard, et al. (1993)
Science 262, 907-909
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Regulation of Membrane Metalloproteolytic Cleavage of L-selectin (CD62L) by the Epidermal Growth Factor Domain.

L.-c. Zhao, M. Shey, M. Farnsworth, and M. O. Dailey (2001)
J. Biol. Chem. 276, 30631-30640
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A B-cell receptor-specific selection step governs immature to mature B cell differentiation.

M. H. Levine, A. M. Haberman, D. B. Sant'Angelo, L. G. Hannum, M. P. Cancro, C. A. Janeway Jr., and M. J. Shlomchik (2000)
PNAS 97, 2743-2748
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