Science 29 October 1993: Vol. 262. no. 5134, pp. 689 - 695 DOI: 10.1126/science.7901908

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Articles

Volatile Anesthetics Attenuate Oxidative Stress-Reduced Activity of Glutamate Transporter Type 3.

S.-A. Lee, J.-G. Choi, and Z. Zuo (2009)
Anesth. Analg. 109, 1506-1510
 |  Abstract »  |  Full Text »  |  PDF »

Direct and Indirect Roles of Cyclin-dependent Kinase 5 as an Upstream Regulator in the c-Jun NH2-Terminal Kinase Cascade: Relevance to Neurotoxic Insults in Alzheimer's Disease.

K.-H. Sun, H.-g. Lee, M. A. Smith, and K. Shah (2009)
Mol. Biol. Cell 20, 4611-4619
 |  Abstract »  |  Full Text »  |  PDF »

Pyridoxine Inhibits Depolarization-Evoked Glutamate Release in Nerve Terminals from Rat Cerebral Cortex: a Possible Neuroprotective Mechanism?.

T.-T. Yang and S.-J. Wang (2009)
J. Pharmacol. Exp. Ther. 331, 244-254
 |  Abstract »  |  Full Text »  |  PDF »

Gene Expression Profiles in Zebrafish Brain after Acute Exposure to Domoic Acid at Symptomatic and Asymptomatic Doses.

K. A. Lefebvre, S. C. Tilton, T. K. Bammler, R. P. Beyer, S. Srinouanprachan, P. L. Stapleton, F. M. Farin, and E. P. Gallagher (2009)
Toxicol. Sci. 107, 65-77
 |  Abstract »  |  Full Text »  |  PDF »

Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits.

R. H. Fontaine, P. Olivier, V. Massonneau, P. Leroux, V. Degos, S. Lebon, V. El Ghouzzi, V. Lelievre, P. Gressens, and O. Baud (2008)
PNAS 105, 16779-16784
 |  Abstract »  |  Full Text »  |  PDF »

An examination of the effects of the antioxidant Pycnogenol(R) on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population.

J. Ryan, K. Croft, T. Mori, K. Wesnes, J. Spong, L. Downey, C. Kure, J. Lloyd, and C. Stough (2008)
J Psychopharmacol 22, 553-562
 |  Abstract »  |  PDF »

Increasing Interaction of Amygdalar Afferents with GABAergic Interneurons between Birth and Adulthood.

M. G. Cunningham, S. Bhattacharyya, and F. M. Benes (2008)
Cereb Cortex 18, 1529-1535
 |  Abstract »  |  Full Text »  |  PDF »

Cognitive Dysfunction and Diabetes Mellitus.

C. T. Kodl and E. R. Seaquist (2008)
Endocr. Rev. 29, 494-511
 |  Abstract »  |  Full Text »  |  PDF »

CCAAT/enhancer binding protein {beta} deficiency provides cerebral protection following excitotoxic injury.

M. Cortes-Canteli, R. Luna-Medina, M. Sanz-SanCristobal, A. Alvarez-Barrientos, A. Santos, and A. Perez-Castillo (2008)
J. Cell Sci. 121, 1224-1234
 |  Abstract »  |  Full Text »  |  PDF »

p66shc Inhibits Pro-survival Epidermal Growth Factor Receptor/ERK Signaling during Severe Oxidative Stress in Mouse Renal Proximal Tubule Cells.

I. Arany, A. Faisal, Y. Nagamine, and R. L. Safirstein (2008)
J. Biol. Chem. 283, 6110-6117
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+/CaM Controls Ca2+-Dependent Inactivation of NMDA Receptors by Dimerizing the NR1 C Termini.

C. Wang, H.-G. Wang, H. Xie, and G. S. Pitt (2008)
J. Neurosci. 28, 1865-1870
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondrial Reactive Oxygen Species Inactivate Neuronal Nicotinic Acetylcholine Receptors and Induce Long-Term Depression of Fast Nicotinic Synaptic Transmission.

V. A. Campanucci, A. Krishnaswamy, and E. Cooper (2008)
J. Neurosci. 28, 1733-1744
 |  Abstract »  |  Full Text »  |  PDF »

Serum Micronutrient Concentrations and Decline in Physical Function Among Older Persons.

B. Bartali, E. A. Frongillo, J. M. Guralnik, M. H. Stipanuk, H. G. Allore, A. Cherubini, S. Bandinelli, L. Ferrucci, and T. M. Gill (2008)
JAMA 299, 308-315
 |  Abstract »  |  Full Text »  |  PDF »

Review: Oxidative stress and excitotoxicity: a therapeutic issue in multiple sclerosis?.

R.E. Gonsette (2008)
Multiple Sclerosis 14, 22-34
 |  Abstract »  |  PDF »

S-nitrosylation of peroxiredoxin 2 promotes oxidative stress-induced neuronal cell death in Parkinson's disease.

J. Fang, T. Nakamura, D.-H. Cho, Z. Gu, and S. A. Lipton (2007)
PNAS 104, 18742-18747
 |  Abstract »  |  Full Text »  |  PDF »

A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment.

G. Schifitto, J. Zhang, S. R. Evans, N. Sacktor, D. Simpson, L. L. Millar, V. L. Hung, E. N. Miller, E. Smith, R. J. Ellis, et al. (2007)
Neurology 69, 1314-1321
 |  Abstract »  |  Full Text »  |  PDF »

Age-Associated Oxidative Macromolecular Damages in Rat Brain Regions: Role of Glutathione Monoester.

G. Murali and C. Panneerselvam (2007)
J. Gerontol. A Biol. Sci. Med. Sci. 62, 824-830
 |  Abstract »  |  Full Text »  |  PDF »

Safety and Tolerability of NXY-059 for Acute Intracerebral Hemorrhage: The CHANT Trial.

P. D. Lyden, A. Shuaib, K. R. Lees, A. Davalos, S. M. Davis, H.-C. Diener, J. C. Grotta, T. J. Ashwood, H.-G. Hardemark, H. H. Svensson, et al. (2007)
Stroke 38, 2262-2269
 |  Abstract »  |  Full Text »  |  PDF »

Searching for Unique Endophenotypes for Schizophrenia and Bipolar Disorder Within Neural Circuits and Their Molecular Regulatory Mechanisms.

F. M. Benes (2007)
Schizophr Bull 33, 932-936
 |  Abstract »  |  Full Text »  |  PDF »

Plasma Carotenoid Levels and Cognitive Performance in an Elderly Population: Results of the EVA Study.

N. T. Akbaraly, H. Faure, V. Gourlet, A. Favier, and C. Berr (2007)
J. Gerontol. A Biol. Sci. Med. Sci. 62, 308-316
 |  Abstract »  |  Full Text »  |  PDF »

Oral Treatment with Rofecoxib Reduces Hippocampal Excitotoxic Neurodegeneration.

S. J. Hewett, J. M. Silakova, and J. A. Hewett (2006)
J. Pharmacol. Exp. Ther. 319, 1219-1224
 |  Abstract »  |  Full Text »  |  PDF »

Neurotoxicity of Domoic Acid in Cerebellar Granule Neurons in a Genetic Model of Glutathione Deficiency.

G. Giordano, C. C. White, L. A. McConnachie, C. Fernandez, T. J. Kavanagh, and L. G. Costa (2006)
Mol. Pharmacol. 70, 2116-2126
 |  Abstract »  |  Full Text »  |  PDF »

Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo.

T. W. Weiss, A. L. Samson, B. Niego, P. B. Daniel, and R. L. Medcalf (2006)
FASEB J 20, 2369-2371
 |  Abstract »  |  Full Text »  |  PDF »

The Endocannabinoid System as an Emerging Target of Pharmacotherapy.

P. Pacher, S. Batkai, and G. Kunos (2006)
Pharmacol. Rev. 58, 389-462
 |  Abstract »  |  Full Text »  |  PDF »

Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels..

J. P. Buschdorf, L. Li Chew, B. Zhang, Q. Cao, F.-Y. Liang, Y.-C. Liou, Y. T. Zhou, and B. C. Low (2006)
J. Cell Sci. 119, 3337-3350
 |  Abstract »  |  Full Text »  |  PDF »

Ganglioside GM3 is involved in neuronal cell death.

H. Sohn, Y.-S. Kim, H.-T. Kim, C.-H. Kim, E.-W. Cho, H.-Y. Kang, N.-S. Kim, C.-H. Kim, S. E. Ryu, J.-H. Lee, et al. (2006)
FASEB J 20, 1248-1250
 |  Abstract »  |  Full Text »  |  PDF »

Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: modulatory role of vitamin C, vitamin E and quercetin.

E O Farombi and O O Onyema (2006)
Human and Experimental Toxicology 25, 251-259
 |  Abstract »  |  PDF »

Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection.

H. Parfenova, S. Basuroy, S. Bhattacharya, D. Tcheranova, Y. Qu, R. F. Regan, and C. W. Leffler (2006)
Am J Physiol Cell Physiol 290, C1399-C1410
 |  Abstract »  |  Full Text »  |  PDF »

Prostaglandin H synthase-catalyzed bioactivation of amphetamines to free radical intermediates that cause CNS regional DNA oxidation and nerve terminal degeneration.

W. Jeng, A. Ramkissoon, T. Parman, and P. G. Wells (2006)
FASEB J 20, 638-650
 |  Abstract »  |  Full Text »  |  PDF »

Protein kinase C{delta}-mediated proteasomal degradation of MAP kinase phosphatase-1 contributes to glutamate-induced neuronal cell death.

B.-H. Choi, E.-M. Hur, J.-H. Lee, D.-J. Jun, and K.-T. Kim (2006)
J. Cell Sci. 119, 1329-1340
 |  Abstract »  |  Full Text »  |  PDF »

Ester Derivatives of Tournefolic Acid B Attenuate N-Methyl-D-aspartate-Mediated Excitotoxicity in Rat Cortical Neurons.

C.-N. Wang, H.-C. Pan, Y.-L. Lin, C.-W. Chi, and Y.-J. Shiao (2006)
Mol. Pharmacol. 69, 950-959
 |  Abstract »  |  Full Text »  |  PDF »

MTH1, an Oxidized Purine Nucleoside Triphosphatase, Suppresses the Accumulation of Oxidative Damage of Nucleic Acids in the Hippocampal Microglia during Kainate-Induced Excitotoxicity.

K. Kajitani, H. Yamaguchi, Y. Dan, M. Furuichi, D. Kang, and Y. Nakabeppu (2006)
J. Neurosci. 26, 1688-1698
 |  Abstract »  |  Full Text »  |  PDF »

Expression of a Familial Alzheimer's Disease-Linked Presenilin-1 Variant Enhances Perforant Pathway Lesion-Induced Neuronal Loss in the Entorhinal Cortex.

O. Lazarov, L. D. Peterson, D. A. Peterson, and S. S. Sisodia (2006)
J. Neurosci. 26, 429-434
 |  Abstract »  |  Full Text »  |  PDF »

Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress.

L. Tretter and V. Adam-Vizi (2005)
Phil Trans R Soc B 360, 2335-2345
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Matrix Metalloproteinase-9 via Neuronal Nitric Oxide Synthase Contributes to NMDA-Induced Retinal Ganglion Cell Death.

S.-i. Manabe, Z. Gu, and S. A. Lipton (2005)
Invest. Ophthalmol. Vis. Sci. 46, 4747-4753
 |  Abstract »  |  Full Text »  |  PDF »

Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor.

A. Ledo, R. M. Barbosa, G. A. Gerhardt, E. Cadenas, and J. Laranjinha (2005)
PNAS 102, 17483-17488
 |  Abstract »  |  Full Text »  |  PDF »

A Small-Molecule-Inducible Nrf2-Mediated Antioxidant Response Provides Effective Prophylaxis against Cerebral Ischemia In Vivo.

A. Y. Shih, P. Li, and T. H. Murphy (2005)
J. Neurosci. 25, 10321-10335
 |  Abstract »  |  Full Text »  |  PDF »

Hydrogen peroxide alters membrane and cytoskeleton properties and increases intercellular connections in astrocytes.

D. Zhu, K. S. Tan, X. Zhang, A. Y. Sun, G. Y. Sun, and J. C.-M. Lee (2005)
J. Cell Sci. 118, 3695-3703
 |  Abstract »  |  Full Text »  |  PDF »

Induction of the Nrf2-driven Antioxidant Response Confers Neuroprotection during Mitochondrial Stress in Vivo.

A. Y. Shih, S. Imbeault, V. Barakauskas, H. Erb, L. Jiang, P. Li, and T. H. Murphy (2005)
J. Biol. Chem. 280, 22925-22936
 |  Abstract »  |  Full Text »  |  PDF »

Evidence of increased oxidative damage in subjects with mild cognitive impairment.

J. N. Keller, F. A. Schmitt, S. W. Scheff, Q. Ding, Q. Chen, D. A. Butterfield, and W. R. Markesbery (2005)
Neurology 64, 1152-1156
 |  Abstract »  |  Full Text »  |  PDF »

N-methyl-D-aspartate receptor activation in human cerebral endothelium promotes intracellular oxidant stress.

C. D. Sharp, J. Houghton, J. W. Elrod, A. Warren, T. H. Jackson IV, A. Jawahar, A. Nanda, A. Minagar, and J. S. Alexander (2005)
Am J Physiol Heart Circ Physiol 288, H1893-H1899
 |  Abstract »  |  Full Text »  |  PDF »

Reversible Oxidation of ERK-directed Protein Phosphatases Drives Oxidative Toxicity in Neurons.

D. J. Levinthal and D. B. DeFranco (2005)
J. Biol. Chem. 280, 5875-5883
 |  Abstract »  |  Full Text »  |  PDF »

The Molecular Basis of Oxidative Stress-Induced Cell Death in an Immortalized Retinal Ganglion Cell Line.

P. Maher and A. Hanneken (2005)
Invest. Ophthalmol. Vis. Sci. 46, 749-757
 |  Abstract »  |  Full Text »  |  PDF »

A novel apoptosis pathway activated by the carboxyl terminus of p21.

C. Dong, Q. Li, S.-c. Lyu, A. M. Krensky, and C. Clayberger (2005)
Blood 105, 1187-1194
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondrial failures in Alzheimer's disease.

X. Zhu, M. A. Smith, G. Perry, and G. Aliev (2004)
American Journal of Alzheimer's Disease and Other Dementias 19, 345-352
 |  Abstract »  |  PDF »

The Role of Reactive Oxygen Species (ROS) in Persistent Pain.

J. M. Chung (2004)
Mol. Interv. 4, 248-250
 |  Abstract »  |  Full Text »  |  PDF »

The {beta}1 Subunit Enhances Oxidative Regulation of Large-Conductance Calcium-activated K+ Channels.

L. C. Santarelli, J. Chen, S. H. Heinemann, and T. Hoshi (2004)
J. Gen. Physiol. 124, 357-370
 |  Abstract »  |  Full Text »  |  PDF »

Nutrition- and Virus-Induced Stress Represses the Expression of Manganese Superoxide Dismutase in Vitro.

M. M. Berger, X. Y. Jia, V. Legay, M. Aymard, J. G. Tilles, and B. Lina (2004)
Experimental Biology and Medicine 229, 843-849
 |  Abstract »  |  Full Text »  |  PDF »

A Novel and Potent Poly(ADP-Ribose) Polymerase-1 Inhibitor, FR247304 (5-Chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), Attenuates Neuronal Damage in in Vitro and in Vivo Models of Cerebral Ischemia.

A. Iwashita, N. Tojo, S. Matsuura, S. Yamazaki, K. Kamijo, J. Ishida, H. Yamamoto, K. Hattori, N. Matsuoka, and S. Mutoh (2004)
J. Pharmacol. Exp. Ther. 310, 425-436
 |  Abstract »  |  Full Text »  |  PDF »

Photoreceptor Death, Trophic Factor Expression, Retinal Oxygen Status, and Photoreceptor Function in the P23H Rat.

D.-Y. Yu, S. Cringle, K. Valter, N. Walsh, D. Lee, and J. Stone (2004)
Invest. Ophthalmol. Vis. Sci. 45, 2013-2019
 |  Abstract »  |  Full Text »  |  PDF »

Rat cerebellar granule cells are protected from glutamate-induced excitotoxicity by S-nitrosoglutathione but not glutathione.

C.-Y. Li, T.-Y. Chin, and S.-H. Chueh (2004)
Am J Physiol Cell Physiol 286, C893-C904
 |  Abstract »  |  Full Text »  |  PDF »

Transient Phosphatidylinositol 3-Kinase Inhibition Protects Immature Primary Cortical Neurons from Oxidative Toxicity via Suppression of Extracellular Signal-regulated Kinase Activation.

D. J. Levinthal and D. B. DeFranco (2004)
J. Biol. Chem. 279, 11206-11213
 |  Abstract »  |  Full Text »  |  PDF »

ORP150/HSP12A Regulates Purkinje Cell Survival: A Role for Endoplasmic Reticulum Stress in Cerebellar Development.

Y. Kitao, K. Hashimoto, T. Matsuyama, H. Iso, T. Tamatani, O. Hori, D. M. Stern, M. Kano, K. Ozawa, and S. Ogawa (2004)
J. Neurosci. 24, 1486-1496
 |  Abstract »  |  Full Text »  |  PDF »

JNK-dependent Phosphorylation of c-Jun on Serine 63 Mediates Nitric Oxide-induced Apoptosis of Neuroblastoma Cells.

L. Li, Z. Feng, and A. G. Porter (2004)
J. Biol. Chem. 279, 4058-4065
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor E2-Related Factor 2-Dependent Antioxidant Response Element Activation by tert-Butylhydroquinone and Sulforaphane Occurring Preferentially in Astrocytes Conditions Neurons against Oxidative Insult.

A. D. Kraft, D. A. Johnson, and J. A. Johnson (2004)
J. Neurosci. 24, 1101-1112
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Potent Radical Scavenger, 8-(4-Fluorophenyl)-2-((2E)-3-phenyl-2-propenoyl)-1,2,3,4-tetrahydropyrazolo[5,1-c] [1,2,4]triazine (FR210575), Prevents Neuronal Cell Death in Cultured Primary Neurons and Attenuates Brain Injury after Focal Ischemia in Rats.

A. Iwashita, T. Maemoto, H. Nakada, I. Shima, N. Matsuoka, and H. Hisajima (2003)
J. Pharmacol. Exp. Ther. 307, 961-968
 |  Abstract »  |  Full Text »  |  PDF »

Glutamate causes a loss in human cerebral endothelial barrier integrity through activation of NMDA receptor.

C. D. Sharp, I. Hines, J. Houghton, A. Warren, T. H. Jackson IV, A. Jawahar, A. Nanda, J. W. Elrod, A. Long, A. Chi, et al. (2003)
Am J Physiol Heart Circ Physiol 285, H2592-H2598
 |  Abstract »  |  Full Text »  |  PDF »

Neuroprotective Effect of(-){Delta}9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-D-Aspartate-Induced Retinal Neurotoxicity: Involvement of Peroxynitrite.

A. B. El-Remessy, I. E. Khalil, S. Matragoon, G. Abou-Mohamed, N.-J. Tsai, P. Roon, R. B. Caldwell, R. W. Caldwell, K. Green, and G. I. Liou (2003)
Am. J. Pathol. 163, 1997-2008
 |  Abstract »  |  Full Text »  |  PDF »

CB1 Cannabinoid Receptors and On-Demand Defense Against Excitotoxicity.

G. Marsicano, S. Goodenough, K. Monory, H. Hermann, M. Eder, A. Cannich, S. C. Azad, M. G. Cascio, S. O. Gutierrez, M. van der Stelt, et al. (2003)
Science 302, 84-88
 |  Abstract »  |  Full Text »  |  PDF »

Neurodegeneration in Striatum Induced by the Mitochondrial Toxin 3-Nitropropionic Acid: Role of Matrix Metalloproteinase-9 in Early Blood-Brain Barrier Disruption?.

G. W. Kim, Y. Gasche, S. Grzeschik, J.-C. Copin, C. M. Maier, and P. H. Chan (2003)
J. Neurosci. 23, 8733-8742
 |  Abstract »  |  Full Text »  |  PDF »

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway.

S. Lehnardt, L. Massillon, P. Follett, F. E. Jensen, R. Ratan, P. A. Rosenberg, J. J. Volpe, and T. Vartanian (2003)
PNAS 100, 8514-8519
 |  Abstract »  |  Full Text »  |  PDF »

Equine Estrogens Differentially Prevent Neuronal Cell Death Induced by Glutamate.

B. R. Bhavnani, M. Berco, and J. Binkley (2003)
Reproductive Sciences 10, 302-308
 |  Abstract »  |  PDF »

An Estrogen Replacement Therapy Containing Nine Synthetic Plant-Based Conjugated Estrogens Promotes Neuronal Survival.

L. Zhao, S. Chen, and R. D. Brinton (2003)
Experimental Biology and Medicine 228, 823-835
 |  Abstract »  |  Full Text »  |  PDF »

Chloride Influx Aggravates Ca2+-Dependent AMPA Receptor-Mediated Motoneuron Death.

P. Van Damme, G. Callewaert, J. Eggermont, W. Robberecht, and L. Van Den Bosch (2003)
J. Neurosci. 23, 4942-4950
 |  Abstract »  |  Full Text »  |  PDF »

Degeneration of the Amygdala/Piriform Cortex and Enhanced Fear/Anxiety Behaviors in Sodium Pump {alpha}2 Subunit (Atp1a2)-Deficient Mice.

K. Ikeda, T. Onaka, M. Yamakado, J. Nakai, T.-o Ishikawa, M. M. Taketo, and K. Kawakami (2003)
J. Neurosci. 23, 4667-4676
 |  Abstract »  |  Full Text »  |  PDF »

NMDA Receptor Overactivation Inhibits Phospholipid Synthesis by Decreasing Choline-Ethanolamine Phosphotransferase Activity.

T. Gasull, E. Sarri, N. DeGregorio-Rocasolano, and R. Trullas (2003)
J. Neurosci. 23, 4100-4107
 |  Abstract »  |  Full Text »  |  PDF »

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress.

A. Y. Shih, D. A. Johnson, G. Wong, A. D. Kraft, L. Jiang, H. Erb, J. A. Johnson, and T. H. Murphy (2003)
J. Neurosci. 23, 3394-3406
 |  Abstract »  |  Full Text »  |  PDF »

DNA Fragmentation Decreased in Schizophrenia but Not Bipolar Disorder.

F. M. Benes, J. Walsh, S. Bhattacharyya, A. Sheth, and S. Berretta (2003)
Arch Gen Psychiatry 60, 359-364
 |  Abstract »  |  Full Text »  |  PDF »

Sustained Depolarization and ADP-Ribose Activate a Common Ionic Current in Rat Peritoneal Macrophages.

B. Campo, A. Surprenant, and R. A. North (2003)
J. Immunol. 170, 1167-1173
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide signaling specificity -- the heart of the problem.

D. S. Bredt (2003)
J. Cell Sci. 116, 9-15
 |  Abstract »  |  Full Text »  |  PDF »

Risk Factors for Alzheimer's Disease: Role of Multiple Antioxidants, Non-Steroidal Anti-inflammatory and Cholinergic Agents Alone or in Combination in Prevention and Treatment.

K. N. Prasad, W. C. Cole, and K. C. Prasad (2002)
J. Am. Coll. Nutr. 21, 506-522
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency in Matrix Metalloproteinase Gelatinase B (MMP-9) Protects against Retinal Ganglion Cell Death after Optic Nerve Ligation.

S. K. Chintala, X. Zhang, J. S. Austin, and M. E. Fini (2002)
J. Biol. Chem. 277, 47461-47468
 |  Abstract »  |  Full Text »  |  PDF »

The Origin and Neuronal Function of In Vivo Nonsynaptic Glutamate.

D. A. Baker, Z.-X. Xi, H. Shen, C. J. Swanson, and P. W. Kalivas (2002)
J. Neurosci. 22, 9134-9141
 |  Abstract »  |  Full Text »  |  PDF »

Role of Ubiquilin Associated with Protein-disulfide Isomerase in the Endoplasmic Reticulum in Stress-induced Apoptotic Cell Death.

H. S. Ko, T. Uehara, and Y. Nomura (2002)
J. Biol. Chem. 277, 35386-35392
 |  Abstract »  |  Full Text »  |  PDF »

NMDA sensitization and stimulation by peroxynitrite, nitric oxide, and organic solvents as the mechanism of chemical sensitivity in multiple chemical sensitivity.

M. L. PALL (2002)
FASEB J 16, 1407-1417
 |  Abstract »  |  Full Text »  |  PDF »

Neuronal Differentiation and Protection from Nitric Oxide-Induced Apoptosis Require c-Jun-Dependent Expression of NCAM140.

Z. Feng, L. Li, P. Y. Ng, and A. G. Porter (2002)
Mol. Cell. Biol. 22, 5357-5366
 |  Abstract »  |  Full Text »  |  PDF »

Antioxidant Therapy in Acute Central Nervous System Injury: Current State.

Y. Gilgun-Sherki, Z. Rosenbaum, E. Melamed, and D. Offen (2002)
Pharmacol. Rev. 54, 271-284
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Functional Expression of Human Short TRP7, a Candidate Protein for Store-operated Ca2+ Influx.

A. Riccio, C. Mattei, R. E. Kelsell, A. D. Medhurst, A. R. Calver, A. D. Randall, J. B. Davis, C. D. Benham, and M. N. Pangalos (2002)
J. Biol. Chem. 277, 12302-12309
 |  Abstract »  |  Full Text »  |  PDF »

Rapid and reversible changes in dendrite morphology and synaptic efficacy following NMDA receptor activation: implication for a cellular defense against excitotoxicity.

Y. Ikegaya, J.-A. Kim, M. Baba, T. Iwatsubo, N. Nishiyama, and N. Matsuki (2002)
J. Cell Sci. 114, 4083-4093
 |  Abstract »  |  Full Text »  |  PDF »

The high-altitude brain.

T. F. Hornbein (2002)
J. Exp. Biol. 204, 3129-3132
 |  Abstract »  |  Full Text »  |  PDF »

Histidines 578 and 587 in the S5-S6 Linker of the Human Ether-a-gogo Related Gene-1 K+ Channels Confer Sensitivity to Reactive Oxygen Species.

A. Pannaccione, P. Castaldo, E. Ficker, L. Annunziato, and M. Taglialatela (2002)
J. Biol. Chem. 277, 8912-8919
 |  Abstract »  |  Full Text »  |  PDF »

Manganese Superoxide Dismutase Deficiency Exacerbates Cerebral Infarction After Focal Cerebral Ischemia/Reperfusion in Mice: Implications for the Production and Role of Superoxide Radicals.

G. W. Kim, T. Kondo, N. Noshita, and P. H. Chan (2002)
Stroke 33, 809-815
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Protection of HLE B-3 Cells against Hydrogen Peroxide- and Naphthalene-Induced Lipid Peroxidation and Apoptosis by Transfection with hGSTA1 and hGSTA2.

Y. Yang, R. Sharma, J.-Z. Cheng, M. K. Saini, N. H. Ansari, U. P. Andley, S. Awasthi, and Y. C. Awasthi (2002)
Invest. Ophthalmol. Vis. Sci. 43, 434-445
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From the Cover: Delayed-onset ataxia in mice lacking alpha -tocopherol transfer protein: Model for neuronal degeneration caused by chronic oxidative stress.

T. Yokota, K. Igarashi, T. Uchihara, K.-i. Jishage, H. Tomita, A. Inaba, Y. Li, M. Arita, H. Suzuki, H. Mizusawa, et al. (2001)
PNAS 98, 15185-15190
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Pictorial Review of Glutamate Excitotoxicity: Fundamental Concepts for Neuroimaging.

L. P. Mark, R. W. Prost, J. L. Ulmer, M. M. Smith, D. L. Daniels, J. M. Strottmann, W. D. Brown, and L. Hacein-Bey (2001)
AJNR Am. J. Neuroradiol. 22, 1813-1824
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Calcium Entry through L-type Calcium Channels Causes Mitochondrial Disruption and Chromaffin Cell Death.

M. F. Cano-Abad, M. Villarroya, A. G. Garcia, N. H. Gabilan, and M. G. Lopez (2001)
J. Biol. Chem. 276, 39695-39704
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Inherited neurodegenerative diseases: the one-hit model of neurodegeneration.

G. Clarke, C. J. Lumsden, and R. R. McInnes (2001)
Hum. Mol. Genet. 10, 2269-2275
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Ebselen Reduces Cytochrome c Release From Mitochondria and Subsequent DNA Fragmentation After Transient Focal Cerebral Ischemia in Mice.

S. Namura, I. Nagata, S. Takami, H. Masayasu, and H. Kikuchi (2001)
Stroke 32, 1906-1911
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Depletion of circulating {alpha}2-antiplasmin by intravenous plasmin or immunoneutralization reduces focal cerebral ischemic injury in the absence of arterial recanalization.

N. Nagai, M. De Mol, B. Van Hoef, M. Verstreken, and D. Collen (2001)
Blood 97, 3086-3092
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How Protein Kinase C Activation Protects Nerve Cells from Oxidative Stress-Induced Cell Death.

P. Maher (2001)
J. Neurosci. 21, 2929-2938
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Neuroprotection Mediated by Glial Cell Line-Derived Neurotrophic Factor: Involvement of a Reduction of NMDA-Induced Calcium Influx by the Mitogen-Activated Protein Kinase Pathway.

O. Nicole, C. Ali, F. Docagne, L. Plawinski, E. T. MacKenzie, D. Vivien, and A. Buisson (2001)
J. Neurosci. 21, 3024-3033
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Hypoglycemia Enhances Ionotropic But Reduces Metabotropic Glutamate Responses in Substantia Nigra Dopaminergic Neurons.

S. Marinelli, M. Federici, P. Giacomini, G. Bernardi, and N. B. Mercuri (2001)
J Neurophysiol 85, 1159-1166
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Behavioral Activation in Rats Requires Endogenous Ascorbate Release in Striatum.

G. V. Rebec and Z. Wang (2001)
J. Neurosci. 21, 668-675
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Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity.

F. DABBENI-SALA, S. DI SANTO, D. FRANCESCHINI, S. D. SKAPER, and P. GIUSTI (2001)
FASEB J 15, 164-170
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Unequal Expression of Allelic Kainate Receptor GluR7 mRNAs in Human Brains.

H. H. Schiffer, G. T. Swanson, E. Masliah, and S. F. Heinemann (2000)
J. Neurosci. 20, 9025-9033
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RGC Death in Mice after Optic Nerve Crush Injury: Oxidative Stress and Neuroprotection.

H. Levkovitch–Verbin, C. Harris–Cerruti, Y. Groner, L. A. Wheeler, M. Schwartz, and E. Yoles (2000)
Invest. Ophthalmol. Vis. Sci. 41, 4169-4174
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NMDA and Glutamate Evoke Excitotoxicity at Distinct Cellular Locations in Rat Cortical Neurons In Vitro.

J. D. Sinor, S. Du, S. Venneti, R. C. Blitzblau, D. N. Leszkiewicz, P. A. Rosenberg, and E. Aizenman (2000)
J. Neurosci. 20, 8831-8837
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Neuroprotective Role of Dopamine Against Hippocampal Cell Death.

Y. Bozzi, D. Vallone, and E. Borrelli (2000)
J. Neurosci. 20, 8643-8649
 |  Abstract »  |  Full Text »  |  PDF »

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