Science 30 July 1993: Vol. 261. no. 5121, pp. 600 - 603 DOI: 10.1126/science.8342023

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Articles

Inhibition of the SDF-1{alpha}-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice.

A. Kawaguchi, Y. Orba, T. Kimura, H. Iha, M. Ogata, T. Tsuji, A. Ainai, T. Sata, T. Okamoto, W. W. Hall, et al. (2009)
Blood 114, 2961-2968
 |  Abstract »  |  Full Text »  |  PDF »

Prognostic Significance of CXCL12 Expression in Patients With Colorectal Carcinoma.

Y. Akishima-Fukasawa, Y. Nakanishi, Y. Ino, Y. Moriya, Y. Kanai, and S. Hirohashi (2009)
Am J Clin Pathol 132, 202-210
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CXCR4/CXCL12 Hyperexpression Plays a Pivotal Role in the Pathogenesis of Lupus.

A. Wang, A.-M. Fairhurst, K. Tus, S. Subramanian, Y. Liu, F. Lin, P. Igarashi, X. J. Zhou, F. Batteux, D. Wong, et al. (2009)
J. Immunol. 182, 4448-4458
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Inhibition of Gluconeogenesis in Primary Hepatocytes by Stromal Cell-derived Factor-1 (SDF-1) through a c-Src/Akt-dependent Signaling Pathway.

H.-Y. Liu, G.-B. Wen, J. Han, T. Hong, D. Zhuo, Z. Liu, and W. Cao (2008)
J. Biol. Chem. 283, 30642-30649
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Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation.

Y. Lee, J. M. Kim, and E. J. Lee (2008)
J. Endocrinol. 199, 191-199
 |  Abstract »  |  Full Text »  |  PDF »

SDF-1{alpha} Promotes Invasion of Head and Neck Squamous Cell Carcinoma by Activating NF-{kappa}B.

A. O. Rehman and C.-Y. Wang (2008)
J. Biol. Chem. 283, 19888-19894
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The small GTPase Ral mediates SDF-1-induced migration of B cells and multiple myeloma cells.

D. J. J. de Gorter, R. M. Reijmers, E. A. Beuling, H. P. H. Naber, A. Kuil, M. J. Kersten, S. T. Pals, and M. Spaargaren (2008)
Blood 111, 3364-3372
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The Role of CXCR7/RDC1 as a Chemokine Receptor for CXCL12/SDF-1 in Prostate Cancer.

J. Wang, Y. Shiozawa, J. Wang, Y. Wang, Y. Jung, K. J. Pienta, R. Mehra, R. Loberg, and R. S. Taichman (2008)
J. Biol. Chem. 283, 4283-4294
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Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium.

Z. Pasha, Y. Wang, R. Sheikh, D. Zhang, T. Zhao, and M. Ashraf (2008)
Cardiovasc Res 77, 134-142
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PD-1 and PD-1 ligands: from discovery to clinical application.

T. Okazaki and T. Honjo (2007)
Int. Immunol.
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of an Autocrine Stromal Cell Derived Factor-1/CXCR4 System on the Distant Metastasis of Human Oral Squamous Cell Carcinoma.

D. Uchida, T. Onoue, Y. Tomizuka, N. M. Begum, Y. Miwa, H. Yoshida, and M. Sato (2007)
Mol. Cancer Res. 5, 685-694
 |  Abstract »  |  Full Text »  |  PDF »

Cloning, Characterization, and Molecular Application of a Beta-Agarase Gene from Vibrio sp. Strain V134.

W.-w. Zhang and L. Sun (2007)
Appl. Envir. Microbiol. 73, 2825-2831
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of interleukin-7 and interleukin-3 with the CXCL12-induced proliferation of B-cell progenitor acute lymphoblastic leukemia.

J. Juarez, R. Baraz, S. Gaundar, K. Bradstock, and L. Bendall (2007)
Haematologica 92, 450-459
 |  Abstract »  |  Full Text »  |  PDF »

Multiple actions of the chemokine stromal cell-derived factor-1{alpha} on neuronal activity.

A. Guyon and J.-L. Nahon (2007)
J. Mol. Endocrinol. 38, 365-376
 |  Abstract »  |  Full Text »  |  PDF »

Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis.

I. Kryczek, S. Wei, E. Keller, R. Liu, and W. Zou (2007)
Am J Physiol Cell Physiol 292, C987-C995
 |  Abstract »  |  Full Text »  |  PDF »

FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc.

T. Nakayama, N. Mutsuga, and G. Tosato (2007)
Blood 109, 1363-1372
 |  Abstract »  |  Full Text »  |  PDF »

Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth..

T. Fushimi, T. P. O'Connor, and R. G. Crystal (2006)
Cancer Res. 66, 3513-3522
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Nitric Oxide Cytoskeletal-Induced Alterations Reverse the Endothelial Progenitor Cell Migratory Defect Associated With Diabetes.

M. S. Segal, R. Shah, A. Afzal, C. M. Perrault, K. Chang, A. Schuler, E. Beem, L. C. Shaw, S. Li Calzi, J. K. Harrison, et al. (2006)
Diabetes 55, 102-109
 |  Abstract »  |  Full Text »  |  PDF »

SDF1-3'A Gene Polymorphism Is Associated with Chronic Myeloproliferative Disease and Thrombotic Events.

G. Gerli, C. Vanelli, O. Turri, M. Erario, A. Gardellini, M. Pugliano, and M. L. Biondi (2005)
Clin. Chem. 51, 2411-2414
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Selective Identification of Secreted and Transmembrane Breast Cancer Markers using Escherichia coli Ampicillin Secretion Trap.

D. A. Ferguson, M. R. Muenster, Q. Zang, J. A. Spencer, J. J. Schageman, Y. Lian, H. R. Garner, R. B. Gaynor, J. W. Huff, A. Pertsemlidis, et al. (2005)
Cancer Res. 65, 8209-8217
 |  Abstract »  |  Full Text »  |  PDF »

Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells.

M. Burger, T. Hartmann, M. Krome, J. Rawluk, H. Tamamura, N. Fujii, T. J. Kipps, and J. A. Burger (2005)
Blood 106, 1824-1830
 |  Abstract »  |  Full Text »  |  PDF »

Hematopoietic stem cell trafficking in liver injury.

E. Dalakas, P. N. Newsome, D. J. Harrison, and J. N. Plevris (2005)
FASEB J 19, 1225-1231
 |  Abstract »  |  Full Text »  |  PDF »

A coupled yeast signal sequence trap and transient plant expression strategy to identify genes encoding secreted proteins from peach pistils.

H. Yamane, S.-J. Lee, B.-D. Kim, R. Tao, and J. K. C. Rose (2005)
J. Exp. Bot. 56, 2229-2238
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Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1{alpha} in the circulation.

D. A. Davis, K. E. Singer, M. De La Luz Sierra, M. Narazaki, F. Yang, H. M. Fales, R. Yarchoan, and G. Tosato (2005)
Blood 105, 4561-4568
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Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells.

A. Kortesidis, A. Zannettino, S. Isenmann, S. Shi, T. Lapidot, and S. Gronthos (2005)
Blood 105, 3793-3801
 |  Abstract »  |  Full Text »  |  PDF »

The chemokine SDF-1 differentially regulates axonal elongation and branching in hippocampal neurons.

F. Pujol, P. Kitabgi, and H. Boudin (2005)
J. Cell Sci. 118, 1071-1080
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A Genome Wide Screening Approach for Membrane-targeted Proteins.

H. Jaaro, Z. Levy, and M. Fainzilber (2005)
Mol. Cell. Proteomics 4, 328-333
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Cortisol-induced CXCR4 augmentation mobilizes T lymphocytes after acute physical stress.

M. Okutsu, K. Ishii, K. J. Niu, and R. Nagatomi (2005)
Am J Physiol Regulatory Integrative Comp Physiol 288, R591-R599
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CXCL12 and Vascular Endothelial Growth Factor Synergistically Induce Neoangiogenesis in Human Ovarian Cancers.

I. Kryczek, A. Lange, P. Mottram, X. Alvarez, P. Cheng, M. Hogan, L. Moons, S. Wei, L. Zou, V. Machelon, et al. (2005)
Cancer Res. 65, 465-472
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Preventing Stem Cell Incorporation into Choroidal Neovascularization by Targeting Homing and Attachment Factors.

N. Sengupta, S. Caballero, R. N. Mames, A. M. Timmers, D. Saban, and M. B. Grant (2005)
Invest. Ophthalmol. Vis. Sci. 46, 343-348
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Bone Marrow Is a Reservoir for CD4+CD25+ Regulatory T Cells that Traffic through CXCL12/CXCR4 Signals.

L. Zou, B. Barnett, H. Safah, V. F. LaRussa, M. Evdemon-Hogan, P. Mottram, S. Wei, O. David, T. J. Curiel, and W. Zou (2004)
Cancer Res. 64, 8451-8455
 |  Abstract »  |  Full Text »  |  PDF »

The Role of CXCR4 in Maintaining Peripheral B Cell Compartments and Humoral Immunity.

Y. Nie, J. Waite, F. Brewer, M.-J. Sunshine, D. R. Littman, and Y.-R. Zou (2004)
J. Exp. Med. 200, 1145-1156
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Chemokines: Key Regulators of Mononuclear Cell Recruitment in Atherosclerotic Vascular Disease.

C. Weber, A. Schober, and A. Zernecke (2004)
Arterioscler Thromb Vasc Biol 24, 1997-2008
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Vasorin, a transforming growth factor {beta}-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo.

Y. Ikeda, Y. Imai, H. Kumagai, T. Nosaka, Y. Morikawa, T. Hisaoka, I. Manabe, K. Maemura, T. Nakaoka, T. Imamura, et al. (2004)
PNAS 101, 10732-10737
 |  Abstract »  |  Full Text »  |  PDF »

Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas.

L. Trentin, A. Cabrelle, M. Facco, D. Carollo, M. Miorin, A. Tosoni, P. Pizzo, G. Binotto, L. Nicolardi, R. Zambello, et al. (2004)
Blood 104, 502-508
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Evidence for the involvement of SDF-1 and CXCR4 in the disruption of endothelial cell-branching morphogenesis and angiogenesis by TNF-{alpha} and IFN-{gamma}.

O. Salvucci, M. Basik, L. Yao, R. Bianchi, and G. Tosato (2004)
J. Leukoc. Biol. 76, 217-226
 |  Abstract »  |  Full Text »  |  PDF »

Stroma Cell-Derived Factor 1{alpha} Mediates Desensitization of Human Neutrophil Respiratory Burst in Synovial Fluid from Rheumatoid Arthritic Patients.

M. Lenoir, B. Djerdjouri, and A. Perianin (2004)
J. Immunol. 172, 7136-7143
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Gene Transfer of Stromal Cell-Derived Factor-1{alpha} Enhances Ischemic Vasculogenesis and Angiogenesis via Vascular Endothelial Growth Factor/Endothelial Nitric Oxide Synthase-Related Pathway: Next-Generation Chemokine Therapy for Therapeutic Neovascularization.

K.-i. Hiasa, M. Ishibashi, K. Ohtani, S. Inoue, Q. Zhao, S. Kitamoto, M. Sata, T. Ichiki, A. Takeshita, and K. Egashira (2004)
Circulation 109, 2454-2461
 |  Abstract »  |  Full Text »  |  PDF »

Spatial and Temporal Expression of Ligands for CXCR3 and CXCR4 in Human Endometrium.

K. Kitaya, T. Nakayama, N. Daikoku, S. Fushiki, and H. Honjo (2004)
J. Clin. Endocrinol. Metab. 89, 2470-2476
 |  Abstract »  |  Full Text »  |  PDF »

Stromal Cell-Derived Factor-1{alpha} Promotes Melanoma Cell Invasion across Basement Membranes Involving Stimulation of Membrane-Type 1 Matrix Metalloproteinase and Rho GTPase Activities.

R. A. Bartolome, B. G. Galvez, N. Longo, F. Baleux, G. N. P. van Muijen, P. Sanchez-Mateos, A. G. Arroyo, and J. Teixido (2004)
Cancer Res. 64, 2534-2543
 |  Abstract »  |  Full Text »  |  PDF »

Differential processing of stromal-derived factor-1{alpha} and stromal-derived factor-1{beta} explains functional diversity.

M. De La Luz Sierra, F. Yang, M. Narazaki, O. Salvucci, D. Davis, R. Yarchoan, H. H. Zhang, H. Fales, and G. Tosato (2004)
Blood 103, 2452-2459
 |  Abstract »  |  Full Text »  |  PDF »

T cell chemotaxis to lysophosphatidylcholine through the G2A receptor.

C. G. Radu, L. V. Yang, M. Riedinger, M. Au, and O. N. Witte (2004)
PNAS 101, 245-250
 |  Abstract »  |  Full Text »  |  PDF »

Inflammation Controls B Lymphopoiesis by Regulating Chemokine CXCL12 Expression.

Y. Ueda, K. Yang, S. J. Foster, M. Kondo, and G. Kelsoe (2004)
J. Exp. Med. 199, 47-58
 |  Abstract »  |  Full Text »  |  PDF »

Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis.

L. Yao, O. Salvucci, A. R. Cardones, S. T. Hwang, Y. Aoki, M. De La Luz Sierra, A. Sajewicz, S. Pittaluga, R. Yarchoan, and G. Tosato (2003)
Blood 102, 3900-3905
 |  Abstract »  |  Full Text »  |  PDF »

Crucial Role of Stromal Cell-Derived Factor-1{alpha} in Neointima Formation After Vascular Injury in Apolipoprotein E-Deficient Mice.

A. Schober, S. Knarren, M. Lietz, E. A. Lin, and C. Weber (2003)
Circulation 108, 2491-2497
 |  Abstract »  |  Full Text »  |  PDF »

Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo.

S. Villalba, O. Salvucci, Y. Aoki, M. D. L. L. Sierra, G. Gupta, D. Davis, K. Wyvill, R. Little, R. Yarchoan, and G. Tosato (2003)
J. Leukoc. Biol. 74, 880-888
 |  Abstract »  |  Full Text »  |  PDF »

Stem Cell-derived Neural Stem/Progenitor Cell Supporting Factor Is an Autocrine/Paracrine Survival Factor for Adult Neural Stem/Progenitor Cells.

H. Toda, M. Tsuji, I. Nakano, K. Kobuke, T. Hayashi, H. Kasahara, J. Takahashi, A. Mizoguchi, T. Houtani, T. Sugimoto, et al. (2003)
J. Biol. Chem. 278, 35491-35500
 |  Abstract »  |  Full Text »  |  PDF »

E. coli Selection of Human Genes Encoding Secreted and Membrane Proteins Based on cDNA Fusions to a Leaderless {beta}-Lactamase Reporter.

R. Tan, X. Jiang, A. Jackson, P. Jin, J. Yang, E. Lee, B. Duggan, L. L. Stuve, and G. K. Fu (2003)
Genome Res. 13, 1938-1943
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The Chemokine Receptor CXCR4 Is Required for Outgrowth of Colon Carcinoma Micrometastases.

I. S. Zeelenberg, L. Ruuls-Van Stalle, and E. Roos (2003)
Cancer Res. 63, 3833-3839
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of mRNA With Microsomal Fractionation Using a SAGE-Based DNA Microarray System Facilitates Identification of the Genes Encoding Secretory Proteins.

N. Toyoda, S. Nagai, Y. Terashima, K. Motomura, M. Haino, S.-i. Hashimoto, H. Takizawa, and K. Matsushima (2003)
Genome Res. 13, 1728-1736
 |  Abstract »  |  Full Text »  |  PDF »

CXCR4 Regulates Interneuron Migration in the Developing Neocortex.

R. K. Stumm, C. Zhou, T. Ara, F. Lazarini, M. Dubois-Dalcq, T. Nagasawa, V. Hollt, and S. Schulz (2003)
J. Neurosci. 23, 5123-5130
 |  Abstract »  |  Full Text »  |  PDF »

Isolation of cDNAs Encoding Secreted and Transmembrane Proteins from Schistosoma mansoni by a Signal Sequence Trap Method.

D. Smyth, D. P. McManus, M. J. Smout, T. Laha, W. Zhang, and A. Loukas (2003)
Infect. Immun. 71, 2548-2554
 |  Abstract »  |  Full Text »  |  PDF »

Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G{alpha}i proteins and enhances engraftment of competitive, repopulating stem cells.

H. E. Broxmeyer, L. Kohli, C. H. Kim, Y. Lee, C. Mantel, S. Cooper, G. Hangoc, M. Shaheen, X. Li, and D. W. Clapp (2003)
J. Leukoc. Biol. 73, 630-638
 |  Abstract »  |  Full Text »  |  PDF »

Migration of human blood dendritic cells across endothelial cell monolayers: adhesion molecules and chemokines involved in subset-specific transmigration.

G. de la Rosa, N. Longo, J. L. Rodriguez-Fernandez, A. Puig-Kroger, A. Pineda, A. L. Corbi, and P. Sanchez-Mateos (2003)
J. Leukoc. Biol. 73, 639-649
 |  Abstract »  |  Full Text »  |  PDF »

Stromal Cell-Derived Factor 1, a Novel Target of Estrogen Receptor Action, Mediates the Mitogenic Effects of Estradiol in Ovarian and Breast Cancer Cells.

J. M. Hall and K. S. Korach (2003)
Mol. Endocrinol. 17, 792-803
 |  Abstract »  |  Full Text »  |  PDF »

A Role of CXC Chemokine Ligand 12/Stromal Cell-Derived Factor-1/Pre-B Cell Growth Stimulating Factor and Its Receptor CXCR4 in Fetal and Adult T Cell Development in Vivo.

T. Ara, M. Itoi, K. Kawabata, T. Egawa, K. Tokoyoda, T. Sugiyama, N. Fujii, T. Amagai, and T. Nagasawa (2003)
J. Immunol. 170, 4649-4655
 |  Abstract »  |  Full Text »  |  PDF »

Control of axon elongation via an SDF-1{alpha}/Rho/mDia pathway in cultured cerebellar granule neurons.

Y. Arakawa, H. Bito, T. Furuyashiki, T. Tsuji, S. Takemoto-Kimura, K. Kimura, K. Nozaki, N. Hashimoto, and S. Narumiya (2003)
J. Cell Biol. 161, 381-391
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Cutting Edge: Profile of Chemokine Receptor Expression on Human Plasma Cells Accounts for Their Efficient Recruitment to Target Tissues.

T. Nakayama, K. Hieshima, D. Izawa, Y. Tatsumi, A. Kanamaru, and O. Yoshie (2003)
J. Immunol. 170, 1136-1140
 |  Abstract »  |  Full Text »  |  PDF »

beta -Arrestin2 Is Critically Involved in CXCR4-mediated Chemotaxis, and This Is Mediated by Its Enhancement of p38 MAPK Activation.

Y. Sun, Z. Cheng, L. Ma, and G. Pei (2002)
J. Biol. Chem. 277, 49212-49219
 |  Abstract »  |  Full Text »  |  PDF »

Neuronal migration and molecular conservation with leukocyte chemotaxis.

Y. Rao, K. Wong, M. Ward, C. Jurgensen, and J. Y. Wu (2002)
Genes & Dev. 16, 2973-2984
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Interleukin-6 and cAMP Induce Stromal Cell-derived Factor-1 Chemotaxis in Astroglia by Up-regulating CXCR4 Cell Surface Expression. IMPLICATIONS FOR BRAIN INFLAMMATION.

V. Odemis, B. Moepps, P. Gierschik, and J. Engele (2002)
J. Biol. Chem. 277, 39801-39808
 |  Abstract »  |  Full Text »  |  PDF »

Engineered viruses to select genes encoding secreted and membrane-bound proteins in mammalian cells.

P. Moffatt, P. Salois, M.-H. Gaumond, N. St-Amant, E. Godin, and C. Lanctot (2002)
Nucleic Acids Res. 30, 4285-4294
 |  Abstract »  |  Full Text »  |  PDF »

Efficacious immunomodulatory activity of the chemokine stromal cell-derived factor 1 (SDF-1): local secretion of SDF-1 at the tumor site serves as T-cell chemoattractant and mediates T-cell-dependent antitumor responses.

K. Dunussi-Joannopoulos, K. Zuberek, K. Runyon, R. G. Hawley, A. Wong, J. Erickson, S. Herrmann, and J. P. Leonard (2002)
Blood 100, 1551-1558
 |  Abstract »  |  Full Text »  |  PDF »

Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain.

I. Szabo, X.-H. Chen, L. Xin, M. W. Adler, O. M. Z. Howard, J. J. Oppenheim, and T. J. Rogers (2002)
PNAS 99, 10276-10281
 |  Abstract »  |  Full Text »  |  PDF »

A Dual Role for the SDF-1/CXCR4 Chemokine Receptor System in Adult Brain: Isoform-Selective Regulation of SDF-1 Expression Modulates CXCR4-Dependent Neuronal Plasticity and Cerebral Leukocyte Recruitment after Focal Ischemia.

R. K. Stumm, J. Rummel, V. Junker, C. Culmsee, M. Pfeiffer, J. Krieglstein, V. Hollt, and S. Schulz (2002)
J. Neurosci. 22, 5865-5878
 |  Abstract »  |  Full Text »  |  PDF »

Chemokines and chemokine receptors in leukocyte trafficking.

T. S. Olson and K. Ley (2002)
Am J Physiol Regulatory Integrative Comp Physiol 283, R7-R28
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1.

O. Salvucci, L. Yao, S. Villalba, A. Sajewicz, S. Pittaluga, and G. Tosato (2002)
Blood 99, 2703-2711
 |  Abstract »  |  Full Text »  |  PDF »

Functional characterization of podia formation in normal and malignant hematopoietic cells.

S. Fruehauf, K. Srbic, R. Seggewiss, J. Topaly, and A. D. Ho (2002)
J. Leukoc. Biol. 71, 425-432
 |  Abstract »  |  Full Text »  |  PDF »

A Proteomic Approach for Identification of Secreted Proteins during the Differentiation of 3T3-L1 Preadipocytes to Adipocytes.

I. Kratchmarova, D. E. Kalume, B. Blagoev, P. E. Scherer, A. V. Podtelejnikov, H. Molina, P. E. Bickel, J. S. Andersen, M. M. Fernandez, J. Bunkenborg, et al. (2002)
Mol. Cell. Proteomics 1, 213-222
 |  Abstract »  |  Full Text »  |  PDF »

Xenopus laevis Stromal Cell-Derived Factor 1: Conservation of Structure and Function During Vertebrate Development.

M. Braun, M. Wunderlin, K. Spieth, W. Knochel, P. Gierschik, and B. Moepps (2002)
J. Immunol. 168, 2340-2347
 |  Abstract »  |  Full Text »  |  PDF »

Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G0/G1 transition in CD34+ cells: evidence for an autocrine/paracrine mechanism.

J.-J. Lataillade, D. Clay, P. Bourin, F. Herodin, C. Dupuy, C. Jasmin, and M.-C. Le Bousse-Kerdiles (2002)
Blood 99, 1117-1129
 |  Abstract »  |  Full Text »  |  PDF »

Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice.

J. Cashman, I. Clark-Lewis, A. Eaves, and C. Eaves (2002)
Blood 99, 792-799
 |  Abstract »  |  Full Text »  |  PDF »

Preparing a human membrane and secreted protein-enriched cDNA library using PCR primers derived from a genomic database.

Y. Fan, C. Y. Wu, C. W. Chen, T. W. Chang, and C. Lim (2001)
Nucleic Acids Res. 29, e114
 |  Abstract »  |  Full Text »  |  PDF »

Genomewide Trapping of Genes that Encode Secreted and Transmembrane Proteins Repressed by Oncogenic Signaling.

M. Gebauer, H. von Melchner, and T. Beckers (2001)
Genome Res. 11, 1871-1877
 |  Abstract »  |  Full Text »  |  PDF »

AMD3100, a Potent and Specific Antagonist of the Stromal Cell-Derived Factor-1 Chemokine Receptor CXCR4, Inhibits Autoimmune Joint Inflammation in IFN-{gamma} Receptor-Deficient Mice.

P. Matthys, S. Hatse, K. Vermeire, A. Wuyts, G. Bridger, G. W. Henson, E. De Clercq, A. Billiau, and D. Schols (2001)
J. Immunol. 167, 4686-4692
 |  Abstract »  |  Full Text »  |  PDF »

Diverse Transcriptional Response of CD4+ T Cells to Stromal Cell-Derived Factor (SDF)-1: Cell Survival Promotion and Priming Effects of SDF-1 on CD4+ T Cells.

Y. Suzuki, M. Rahman, and H. Mitsuya (2001)
J. Immunol. 167, 3064-3073
 |  Abstract »  |  Full Text »  |  PDF »

A Coordinated Change in Chemokine Responsiveness Guides Plasma Cell Movements.

D. C. Hargreaves, P. L. Hyman, T. T. Lu, V. N. Ngo, A. Bidgol, G. Suzuki, Y.-R. Zou, D. R. Littman, and J. G. Cyster (2001)
J. Exp. Med. 194, 45-56
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Increased Level of Stromal Cell-Derived Factor-1 mRNA in Peripheral Blood Mononuclear Cells from Children with AIDS-related Lymphoma.

S. Sei, D. P. O'Neill, S. K. Stewart, Q.-e. Yang, M. Kumagai, A. M. Boler, M. A. Adde, S. L. Zwerski, L. V. Wood, D. J. Venzon, et al. (2001)
Cancer Res. 61, 5028-5037
 |  Abstract »  |  Full Text »  |  PDF »

A novel regulator of G-protein signaling bearing GAP activity for G{alpha}i and G{alpha}q in megakaryocytes.

Y. Nagata, M. Oda, H. Nakata, Y. Shozaki, T. Kozasa, and K. Todokoro (2001)
Blood 97, 3051-3060
 |  Abstract »  |  Full Text »  |  PDF »

Replacement of the V3 Region of gp120 with SDF-1 Preserves the Infectivity of T-Cell Line-Tropic Human Immunodeficiency Virus Type 1.

A. Yonezawa, T. Hori, A. Takaori-Kondo, R. Morita, and T. Uchiyama (2001)
J. Virol. 75, 4258-4267
 |  Abstract »  |  Full Text »

Expression of Stromal-Derived Factor-1 Is Decreased by IL-1 and TNF and in Dermal Wound Healing.

E. R. Fedyk, D. Jones, H. O. D. Critchley, R. P. Phipps, T. M. Blieden, and T. A. Springer (2001)
J. Immunol. 166, 5749-5754
 |  Abstract »  |  Full Text »  |  PDF »

Stromal cell-derived factor 1{alpha} increases polyploidization of megakaryocytes generated by human hematopoietic progenitor cells.

R. Guerriero, G. Mattia, U. Testa, C. Chelucci, G. Macioce, I. Casella, P. Samoggia, C. Peschle, and H. J. Hassan (2001)
Blood 97, 2587-2595
 |  Abstract »  |  Full Text »  |  PDF »

Coregulation of CXC Chemokine Receptor and CD4 Expression on T Lymphocytes During Allogeneic Activation.

L. M. Ebert and S. R. McColl (2001)
J. Immunol. 166, 4870-4878
 |  Abstract »  |  Full Text »  |  PDF »

Stromal Cell-Derived Factor-1-Induced LFA-1 Activation During In Vivo Migration of T Cell Hybridoma Cells Requires Gq/11, RhoA, and Myosin, as well as Gi and Cdc42.

R. D. M. Soede, I. S. Zeelenberg, Y. M. Wijnands, M. Kamp, and E. Roos (2001)
J. Immunol. 166, 4293-4301
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Stromal derived factor-1{alpha} (SDF-1{alpha}) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway.

M. L. Colamussi, P. Secchiero, A. Gonelli, M. Marchisio, G. Zauli, and S. Capitani (2001)
J. Leukoc. Biol. 69, 263-270
 |  Abstract »  |  Full Text »

Chemokine stromal cell-derived factor-1{alpha} modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1.

F. Sanz-Rodriguez, A. Hidalgo, and J. Teixido (2001)
Blood 97, 346-351
 |  Abstract »  |  Full Text »  |  PDF »

Lack of correlation between chemokine receptor and Th1/Th2 cytokine expression by individual memory T cells.

T. Nanki and P. E. Lipsky (2000)
Int. Immunol. 12, 1659-1667
 |  Abstract »  |  Full Text »  |  PDF »

Stromal Cell-Derived Factor-1-CXC Chemokine Receptor 4 Interactions Play a Central Role in CD4+ T Cell Accumulation in Rheumatoid Arthritis Synovium.

T. Nanki, K. Hayashida, H. S. El-Gabalawy, S. Suson, K. Shi, H. J. Girschick, S. Yavuz, and P. E. Lipsky (2000)
J. Immunol. 165, 6590-6598
 |  Abstract »  |  Full Text »  |  PDF »

Impairment of lymphopoiesis and myelopoiesis in mice reconstituted with bone marrow-hematopoietic progenitor cells expressing SDF-1-intrakine.

N. Onai, Y.-y. Zhang, H. Yoneyama, T. Kitamura, S. Ishikawa, and K. Matsushima (2000)
Blood 96, 2074-2080
 |  Abstract »  |  Full Text »  |  PDF »

Increased Expression of H/T-Cadherin in Tumor-penetrating Blood Vessels.

L. Wyder, A. Vitaliti, H. Schneider, L. W. Hebbard, D. R. Moritz, M. Wittmer, M. Ajmo, and R. Klemenz (2000)
Cancer Res. 60, 4682-4688
 |  Abstract »  |  Full Text »

Netrin-G1: a Novel Glycosyl Phosphatidylinositol-Linked Mammalian Netrin That Is Functionally Divergent from Classical Netrins.

T. Nakashiba, T. Ikeda, S. Nishimura, K. Tashiro, T. Honjo, J. G. Culotti, and S. Itohara (2000)
J. Neurosci. 20, 6540-6550
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Stromal Cell-derived Factor 1 and CXCR4 Ligand Receptor System in Pancreatic Cancer: A Possible Role for Tumor Progression.

T. Koshiba, R. Hosotani, Y. Miyamoto, J. Ida, S. Tsuji, S. Nakajima, M. Kawaguchi, H. Kobayashi, R. Doi, T. Hori, et al. (2000)
Clin. Cancer Res. 6, 3530-3535
 |  Abstract »  |  Full Text »

Cytokines and Cell Surface Molecules Independently Induce CXCR4 Expression on CD4+ CCR7+ Human Memory T Cells.

P. Jourdan, J.-P. Vendrell, M.-F. Huguet, M. Segondy, J. Bousquet, J. Pene, and H. Yssel (2000)
J. Immunol. 165, 716-724
 |  Abstract »  |  Full Text »  |  PDF »

Gi and Gq/11 proteins are involved in dissemination of myeloid leukemia cells to the liver and spleen, whereas bone marrow colonization involves Gq/11 but not Gi.

R. D. M. Soede, Y. M. Wijnands, M. Kamp, M. A. van der Valk, and E. Roos (2000)
Blood 96, 691-698
 |  Abstract »  |  Full Text »  |  PDF »

Cloning of murine glycosyl phosphatidylinositol anchor attachment protein, GPAA1.

Y. Hiroi, R. Chen, H. Sawa, T. Hosoda, S. Kudoh, Y. Kobayashi, H. Aburatani, K. Nagashima, R. Nagai, Y. Yazaki, et al. (2000)
Am J Physiol Cell Physiol 279, C205-C212
 |  Abstract »  |  Full Text »  |  PDF »

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