Science 2 July 1993: Vol. 261. no. 5117, pp. 50 - 58 DOI: 10.1126/science.8316857

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Articles

Removal of the cardiac myosin regulatory light chain increases isometric force production.

K. Pant, J. Watt, M. Greenberg, M. Jones, D. Szczesna-Cordary, and J. R. Moore (2009)
FASEB J 23, 3571-3580
 |  Abstract »  |  Full Text »  |  PDF »

The molecular effects of skeletal muscle myosin regulatory light chain phosphorylation.

M. J. Greenberg, T. R. Mealy, J. D. Watt, M. Jones, D. Szczesna-Cordary, and J. R. Moore (2009)
Am J Physiol Regulatory Integrative Comp Physiol 297, R265-R274
 |  Abstract »  |  Full Text »  |  PDF »

Malignant familial hypertrophic cardiomyopathy D166V mutation in the ventricular myosin regulatory light chain causes profound effects in skinned and intact papillary muscle fibers from transgenic mice.

W. G. L. Kerrick, K. Kazmierczak, Y. Xu, Y. Wang, and D. Szczesna-Cordary (2009)
FASEB J 23, 855-865
 |  Abstract »  |  Full Text »  |  PDF »

Dilated cardiomyopathy: a review.

A Luk, E Ahn, G S Soor, and J Butany (2009)
J. Clin. Pathol. 62, 219-225
 |  Abstract »  |  Full Text »  |  PDF »

Ablation of Ventricular Myosin Regulatory Light Chain Phosphorylation in Mice Causes Cardiac Dysfunction in Situ and Affects Neighboring Myofilament Protein Phosphorylation.

S. B. Scruggs, A. C. Hinken, A. Thawornkaiwong, J. Robbins, L. A. Walker, P. P. de Tombe, D. L. Geenen, P. M. Buttrick, and R. J. Solaro (2009)
J. Biol. Chem. 284, 5097-5106
 |  Abstract »  |  Full Text »  |  PDF »

N-Methyl-D-aspartate Receptor Subunits Are Non-myosin Targets of Myosin Regulatory Light Chain.

G. Bajaj, Y. Zhang, M. I. Schimerlik, A. M. Hau, J. Yang, T. M. Filtz, C. Kioussi, and J. E. Ishmael (2009)
J. Biol. Chem. 284, 1252-1266
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating.

A. J. Engler, C. Carag-Krieger, C. P. Johnson, M. Raab, H.-Y. Tang, D. W. Speicher, J. W. Sanger, J. M. Sanger, and D. E. Discher (2008)
J. Cell Sci. 121, 3794-3802
 |  Abstract »  |  Full Text »  |  PDF »

Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor.

S. Iwai and T. Q. P. Uyeda (2008)
PNAS 105, 16882-16887
 |  Abstract »  |  Full Text »  |  PDF »

Biomolecular pleiomorphism probed by spatial interpolation of coarse models.

M. Rusu, S. Birmanns, and W. Wriggers (2008)
Bioinformatics 24, 2460-2466
 |  Abstract »  |  Full Text »  |  PDF »

Designing Heart Performance by Gene Transfer.

J. Davis, M. V. Westfall, D. Townsend, M. Blankinship, T. J. Herron, G. Guerrero-Serna, W. Wang, E. Devaney, and J. M. Metzger (2008)
Physiol Rev 88, 1567-1651
 |  Abstract »  |  Full Text »  |  PDF »

Muscle and nonmuscle myosins probed by a spin label at equivalent sites in the force-generating domain.

R. V. Agafonov, Y. E. Nesmelov, M. A. Titus, and D. D. Thomas (2008)
PNAS 105, 13397-13402
 |  Abstract »  |  Full Text »  |  PDF »

Actin-binding cleft closure in myosin II probed by site-directed spin labeling and pulsed EPR.

J. C. Klein, A. R. Burr, B. Svensson, D. J. Kennedy, J. Allingham, M. A. Titus, I. Rayment, and D. D. Thomas (2008)
PNAS 105, 12867-12872
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic Myosin Heavy-Chain Mutations Cause Distal Arthrogryposis and Developmental Myosin Myopathy That Persists Postnatally.

H. Tajsharghi, E. Kimber, A.-K. Kroksmark, R. Jerre, M. Tulinius, and A. Oldfors (2008)
Arch Neurol 65, 1083-1090
 |  Abstract »  |  Full Text »  |  PDF »

Effect of low pH on single skeletal muscle myosin mechanics and kinetics.

E. P. Debold, S. E. Beck, and D. M. Warshaw (2008)
Am J Physiol Cell Physiol 295, C173-C179
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the pre-force-generation state in the actomyosin cross-bridge cycle.

M. Sun, M. B. Rose, S. K. Ananthanarayanan, D. J. Jacobs, and C. M. Yengo (2008)
PNAS 105, 8631-8636
 |  Abstract »  |  Full Text »  |  PDF »

Yeast UCS proteins promote actomyosin interactions and limit myosin turnover in cells.

M. Lord, T. E. Sladewski, and T. D. Pollard (2008)
PNAS 105, 8014-8019
 |  Abstract »  |  Full Text »  |  PDF »

Unc45 Activates Hsp90-dependent Folding of the Myosin Motor Domain.

L. Liu, R. Srikakulam, and D. A. Winkelmann (2008)
J. Biol. Chem. 283, 13185-13193
 |  Abstract »  |  Full Text »  |  PDF »

The Mechanism of the Reverse Recovery Step, Phosphate Release, and Actin Activation of Dictyostelium Myosin II.

M. Gyimesi, B. Kintses, A. Bodor, A. Perczel, S. Fischer, C. R. Bagshaw, and A. Malnasi-Csizmadia (2008)
J. Biol. Chem. 283, 8153-8163
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Mechanics of Smooth Muscle Contractile Proteins in Airway Hyperresponsiveness and Asthma.

R. Leguillette and A.-M. Lauzon (2008)
Proceedings of the ATS 5, 40-46
 |  Abstract »  |  Full Text »  |  PDF »

Photocontrol of Kinesin ATPase Activity Using an Azobenzene Derivative.

M. D. Yamada, Y. Nakajima, H. Maeda, and S. Maruta (2007)
J. Biochem. 142, 691-698
 |  Abstract »  |  Full Text »  |  PDF »

MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II.

H. Pannu, V. Tran-Fadulu, C. L. Papke, S. Scherer, Y. Liu, C. Presley, D. Guo, A. L. Estrera, H. J. Safi, A. R. Brasier, et al. (2007)
Hum. Mol. Genet. 16, 2453-2462
 |  Abstract »  |  Full Text »  |  PDF »

Interaction between myosin heavy chain and troponin isoforms modulate cardiac myofiber contractile dynamics.

M. Chandra, M. L. Tschirgi, S. J. Ford, B. K. Slinker, and K. B. Campbell (2007)
Am J Physiol Regulatory Integrative Comp Physiol 293, R1595-R1607
 |  Abstract »  |  Full Text »  |  PDF »

The roles of myosin ATPase activity and myosin light chain relative content in the slowing of type IIB fibers with hindlimb unweighting in rats.

S. Zhong and L. V. Thompson (2007)
Am J Physiol Cell Physiol 293, C723-C728
 |  Abstract »  |  Full Text »  |  PDF »

A closer look at energy transduction in muscle.

H. Onishi and M. F. Morales (2007)
PNAS 104, 12714-12719
 |  Abstract »  |  Full Text »  |  PDF »

Expression and function of COOH-terminal myosin heavy chain isoforms in mouse smooth muscle.

A. F. Martin, S. Bhatti, G. J. Pyne-Geithman, M. Farjah, V. Manaves, L. Walker, R. Franks, A. R. Strauch, and R. J. Paul (2007)
Am J Physiol Cell Physiol 293, C238-C245
 |  Abstract »  |  Full Text »  |  PDF »

Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse {alpha}-cardiac myosin in the laser trap assay.

E. P. Debold, J. P. Schmitt, J. B. Patlak, S. E. Beck, J. R. Moore, J. G. Seidman, C. Seidman, and D. M. Warshaw (2007)
Am J Physiol Heart Circ Physiol 293, H284-H291
 |  Abstract »  |  Full Text »  |  PDF »

Alterations to myofibrillar protein function in nonischemic regions of the heart early after myocardial infarction.

V. S. Rao, L. R. La Bonte, Y. Xu, Z. Yang, B. A. French, and W. H. Guilford (2007)
Am J Physiol Heart Circ Physiol 293, H654-H659
 |  Abstract »  |  Full Text »  |  PDF »

NEW SKELETAL MYOPATHY AND CARDIOMYOPATHY ASSOCIATED WITH A MISSENSE MUTATION IN MYH7.

N. Darin, H. Tajsharghi, I. Ostman-Smith, T. Gilljam, and A. Oldfors (2007)
Neurology 68, 2041-2042
 |  Full Text »  |  PDF »

Enzymatic Activity and Motility of Recombinant Arabidopsis Myosin XI, MYA1.

Y. Hachikubo, K. Ito, J. Schiefelbein, D. J. Manstein, and K. Yamamoto (2007)
Plant Cell Physiol. 48, 886-891
 |  Abstract »  |  Full Text »  |  PDF »

Myosin essential light chain in health and disease.

O. M. Hernandez, M. Jones, G. Guzman, and D. Szczesna-Cordary (2007)
Am J Physiol Heart Circ Physiol 292, H1643-H1654
 |  Abstract »  |  Full Text »  |  PDF »

Role of myosin heavy chain composition in the stretch activation response of rat myocardium.

J. E. Stelzer, S. L. Brickson, M. R. Locher, and R. L. Moss (2007)
J. Physiol. 579, 161-173
 |  Abstract »  |  Full Text »  |  PDF »

Internal strain regulates the nucleotide binding site of the kinesin leading head.

C. Hyeon and J. N. Onuchic (2007)
PNAS 104, 2175-2180
 |  Abstract »  |  Full Text »  |  PDF »

Kinetic Mechanism of Human Myosin IIIA.

A. C. Dose, S. Ananthanarayanan, J. E. Moore, B. Burnside, and C. M. Yengo (2007)
J. Biol. Chem. 282, 216-231
 |  Abstract »  |  Full Text »  |  PDF »

Roles of type II myosin and a tropomyosin isoform in retrograde actin flow in budding yeast.

T. M. Huckaba, T. Lipkin, and L. A. Pon (2006)
J. Cell Biol. 175, 957-969
 |  Abstract »  |  Full Text »  |  PDF »

E22K mutation of RLC that causes familial hypertrophic cardiomyopathy in heterozygous mouse myocardium: effect on cross-bridge kinetics.

D. Dumka, J. Talent, I. Akopova, G. Guzman, D. Szczesna-Cordary, and J. Borejdo (2006)
Am J Physiol Heart Circ Physiol 291, H2098-H2106
 |  Abstract »  |  Full Text »  |  PDF »

A Point Mutation in the SH1 Helix Alters Elasticity and Thermal Stability of Myosin II.

S. Iwai, D. Hanamoto, and S. Chaen (2006)
J. Biol. Chem. 281, 30736-30744
 |  Abstract »  |  Full Text »  |  PDF »

Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia..

N. M. Verrills, S. T. Po'uha, M. L. M. Liu, T. Y. E. Liaw, M. R. Larsen, M. T. Ivery, G. M. Marshall, P. W. Gunning, and M. Kavallaris (2006)
J Natl Cancer Inst 98, 1363-1374
 |  Abstract »  |  Full Text »  |  PDF »

Acceleration of Stretch Activation in Murine Myocardium due to Phosphorylation of Myosin Regulatory Light Chain.

J. E. Stelzer, J. R. Patel, and R. L. Moss (2006)
J. Gen. Physiol. 128, 261-272
 |  Abstract »  |  Full Text »  |  PDF »

Myosin Light Chain 2 Into the Mainstream of Cardiac Development and Contractility.

R. L. Moss and D. P. Fitzsimons (2006)
Circ. Res. 99, 225-227
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Mechanics of actomyosin bonds in different nucleotide states are tuned to muscle contraction.

B. Guo and W. H. Guilford (2006)
PNAS 103, 9844-9849
 |  Abstract »  |  Full Text »  |  PDF »

Aggregation of Partially Unfolded Myosin Subfragment-1 into Spherical Oligomers with Amyloid-Like Dye-Binding Properties.

H. Komatsu, N. Shinotani, Y. Kimori, J.-i. Tokuoka, K. Kaseda, H. Nakagawa, and T. Kodama (2006)
J. Biochem. 139, 989-996
 |  Abstract »  |  Full Text »  |  PDF »

Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats.

H. Haase, G. Dobbernack, G. Tunnemann, P. Karczewski, C. Cardoso, D. Petzhold, W.-P. Schlegel, S. Lutter, P. Pierschalek, J. Behlke, et al. (2006)
FASEB J 20, 865-873
 |  Abstract »  |  Full Text »  |  PDF »

Toward understanding actin activation of myosin ATPase: The role of myosin surface loops.

H. Onishi, S. V. Mikhailenko, and M. F. Morales (2006)
PNAS 103, 6136-6141
 |  Abstract »  |  Full Text »  |  PDF »

Changes in the muscle proteome after compensatory growth in pigs.

R. Lametsch, L. Kristensen, M. R. Larsen, M. Therkildsen, N. Oksbjerg, and P. Ertbjerg (2006)
J Anim Sci 84, 918-924
 |  Abstract »  |  Full Text »  |  PDF »

Expression Profiling of a Hypercontraction-induced Myopathy in Drosophila Suggests a Compensatory Cytoskeletal Remodeling Response.

E. S. Montana and J. T. Littleton (2006)
J. Biol. Chem. 281, 8100-8109
 |  Abstract »  |  Full Text »  |  PDF »

Dynamics of the Upper 50-kDa Domain of Myosin V Examined with Fluorescence Resonance Energy Transfer.

M. Sun, J. L. Oakes, S. K. Ananthanarayanan, K. H. Hawley, R. Y. Tsien, S. R. Adams, and C. M. Yengo (2006)
J. Biol. Chem. 281, 5711-5717
 |  Abstract »  |  Full Text »  |  PDF »

Dependence of cross-bridge kinetics on myosin light chain isoforms in rabbit and rat skeletal muscle fibres.

O. Andruchov, O. Andruchova, Y. Wang, and S. Galler (2006)
J. Physiol. 571, 231-242
 |  Abstract »  |  Full Text »  |  PDF »

Measuring Rotations of a Few Cross-Bridges in Skeletal Muscle.

J. Borejdo, J. Talent, and I. Akopova (2006)
Experimental Biology and Medicine 231, 28-38
 |  Abstract »  |  Full Text »  |  PDF »

Structural Evidence for Non-canonical Binding of Ca2+ to a Canonical EF-hand of a Conventional Myosin.

J. E. Debreczeni, L. Farkas, V. Harmat, C. Hetenyi, I. Hajdu, P. Zavodszky, K. Kohama, and L. Nyitray (2005)
J. Biol. Chem. 280, 41458-41464
 |  Abstract »  |  Full Text »  |  PDF »

Kinetic Effects of Kinesin Switch I and Switch II Mutations.

S. D. Auerbach and K. A. Johnson (2005)
J. Biol. Chem. 280, 37061-37068
 |  Abstract »  |  Full Text »  |  PDF »

Structure of the light chain-binding domain of myosin V.

M. Terrak, G. Rebowski, R. C. Lu, Z. Grabarek, and R. Dominguez (2005)
PNAS 102, 12718-12723
 |  Abstract »  |  Full Text »  |  PDF »

Asymmetric Photocross-Linking of Singly Phosphorylated Smooth Muscle Heavy Meromyosin.

K. Takeya, M. Takahashi, T. Katoh, and M. Yazawa (2005)
J. Biochem. 138, 245-253
 |  Abstract »  |  Full Text »  |  PDF »

The structural basis of the increase in isometric force production with temperature in frog skeletal muscle.

M. Linari, E. Brunello, M. Reconditi, Y.-B. Sun, P. Panine, T. Narayanan, G. Piazzesi, V. Lombardi, and M. Irving (2005)
J. Physiol. 567, 459-469
 |  Abstract »  |  Full Text »  |  PDF »

The E22K mutation of myosin RLC that causes familial hypertrophic cardiomyopathy increases calcium sensitivity of force and ATPase in transgenic mice.

D. Szczesna-Cordary, G. Guzman, J. Zhao, O. Hernandez, J. Wei, and Z. Diaz-Perez (2005)
J. Cell Sci. 118, 3675-3683
 |  Abstract »  |  Full Text »  |  PDF »

Biological, Biochemical, and Kinetic Effects of Mutations of the Cardiomyopathy Loop of Dictyostelium Myosin II: IMPORTANCE OF ALA400.

X. Liu, S. Shu, M. Kovacs, and E. D. Korn (2005)
J. Biol. Chem. 280, 26974-26983
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}-Myosin Heavy Chain: A Sarcomeric Gene Associated With Dilated and Hypertrophic Phenotypes of Cardiomyopathy.

E. Carniel, M. R.G. Taylor, G. Sinagra, A. Di Lenarda, L. Ku, P. R. Fain, M. M. Boucek, J. Cavanaugh, S. Miocic, D. Slavov, et al. (2005)
Circulation 112, 54-59
 |  Abstract »  |  Full Text »  |  PDF »

Binding of pRNA to the N-terminal 14 amino acids of connector protein of bacteriophage phi29.

F. Xiao, W.-D. Moll, S. Guo, and P. Guo (2005)
Nucleic Acids Res. 33, 2640-2649
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Structural mechanism of the recovery stroke in the Myosin molecular motor.

S. Fischer, B. Windshugel, D. Horak, K. C. Holmes, and J. C. Smith (2005)
PNAS 102, 6873-6878
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of the human atrial myosin light chain 1 promoter by Ca2+-calmodulin-dependent signaling pathways.

C. Woischwill, P. Karczewski, H. Bartsch, H.-P. Luther, M. Kott, H. Haase, and I. Morano (2005)
FASEB J 19, 503-511
 |  Abstract »  |  Full Text »  |  PDF »

Role of the N-terminal negative charges of actin in force generation and cross-bridge kinetics in reconstituted bovine cardiac muscle fibres.

X. Lu, M. K Bryant, K. E Bryan, P. A Rubenstein, and M. Kawai (2005)
J. Physiol. 564, 65-82
 |  Abstract »  |  Full Text »  |  PDF »

Site-directed spin labeling reveals a conformational switch in the phosphorylation domain of smooth muscle myosin.

W. D. Nelson, S. E. Blakely, Y. E. Nesmelov, and D. D. Thomas (2005)
PNAS 102, 4000-4005
 |  Abstract »  |  Full Text »  |  PDF »

Hsp90 Protein in Fission Yeast Swo1p and UCS Protein Rng3p Facilitate Myosin II Assembly and Function.

M. Mishra, V. M. D'souza, K. C. Chang, Y. Huang, and M. K. Balasubramanian (2005)
Eukaryot. Cell 4, 567-576
 |  Abstract »  |  Full Text »  |  PDF »

Incorporation of an Azobenzene Derivative into the Energy Transducing Site of Skeletal Muscle Myosin Results in Photo-Induced Conformational Changes.

N. Umeki, T. Yoshizawa, Y. Sugimoto, T. Mitsui, K. Wakabayashi, and S. Maruta (2004)
J. Biochem. 136, 839-846
 |  Abstract »  |  Full Text »  |  PDF »

Kinetic properties of myosin heavy chain isoforms in mouse skeletal muscle: comparison with rat, rabbit, and human and correlation with amino acid sequence.

O. Andruchov, O. Andruchova, Y. Wang, and S. Galler (2004)
Am J Physiol Cell Physiol 287, C1725-C1732
 |  Abstract »  |  Full Text »  |  PDF »

Drosophila crinkled, Mutations of Which Disrupt Morphogenesis and Cause Lethality, Encodes Fly Myosin VIIA.

D. P. Kiehart, J. D. Franke, M. K. Chee, R. A. Montague, T.-l. Chen, J. Roote, and M. Ashburner (2004)
Genetics 168, 1337-1352
 |  Abstract »  |  Full Text »  |  PDF »

Novel Sensors of the Regulatory Switch on the Regulatory Light Chain of Smooth Muscle Myosin.

S. M. Mazhari, C. T. Selser, and C. R. Cremo (2004)
J. Biol. Chem. 279, 39905-39914
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for conformational coupling between two calcium channels.

C. Paolini, J. D. Fessenden, I. N. Pessah, and C. Franzini-Armstrong (2004)
PNAS 101, 12748-12752
 |  Abstract »  |  Full Text »  |  PDF »

Mutation of Perinatal Myosin Heavy Chain Associated with a Carney Complex Variant.

M. Veugelers, M. Bressan, D. A. McDermott, S. Weremowicz, C. C. Morton, C. C. Mabry, J.-F. Lefaivre, A. Zunamon, A. Destree, J.-M. Chaudron, et al. (2004)
N. Engl. J. Med. 351, 460-469
 |  Abstract »  |  Full Text »  |  PDF »

A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin.

J. J. Sherwood, G. S. Waller, D. M. Warshaw, and S. Lowey (2004)
PNAS 101, 10973-10978
 |  Abstract »  |  Full Text »  |  PDF »

Human Deafness Mutation of Myosin VI (C442Y) Accelerates the ADP Dissociation Rate.

O. Sato, H. D. White, A. Inoue, B. Belknap, R. Ikebe, and M. Ikebe (2004)
J. Biol. Chem. 279, 28844-28854
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of Myosin{middle dot}ADP{middle dot}Fluorometal Complexes with Fluorescent Probes and Direct Observation Using Quick-Freeze Deep-Etch Electron Microscopy.

S. Maruta, Y. Uyehara, T. Aihara, and E. Katayama (2004)
J. Biochem. 136, 57-64
 |  Abstract »  |  Full Text »  |  PDF »

Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding.

D. Risal, S. Gourinath, D. M. Himmel, A. G. Szent-Gyorgyi, and C. Cohen (2004)
PNAS 101, 8930-8935
 |  Abstract »  |  Full Text »  |  PDF »

The Sliding Filament Model: 1972-2004.

R. Cooke (2004)
J. Gen. Physiol. 123, 643-656
 |  Full Text »  |  PDF »

The Myosin Cardiac Loop Participates Functionally in the Actomyosin Interaction.

K. Ajtai, S. P. Garamszegi, S. Watanabe, M. Ikebe, and T. P. Burghardt (2004)
J. Biol. Chem. 279, 23415-23421
 |  Abstract »  |  Full Text »  |  PDF »

Is peptide bond cis/trans isomerization a key stage in the chemo-mechanical cycle of motor proteins?.

O. TCHAICHEEYAN (2004)
FASEB J 18, 783-789
 |  Abstract »  |  Full Text »  |  PDF »

The effect of tropomyosin on force and elementary steps of the cross-bridge cycle in reconstituted bovine myocardium.

H. Fujita, X. Lu, M. Suzuki, S. Ishiwata, and M. Kawai (2004)
J. Physiol. 556, 637-649
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of a hypercontraction-induced myopathy in Drosophila caused by mutations in Mhc.

E. S. Montana and J. T. Littleton (2004)
J. Cell Biol. 164, 1045-1054
 |  Abstract »  |  Full Text »  |  PDF »

Chaperone-mediated folding and assembly of myosin in striated muscle.

R. Srikakulam and D. A. Winkelmann (2004)
J. Cell Sci. 117, 641-652
 |  Abstract »  |  Full Text »  |  PDF »

Familial Hypertrophic Cardiomyopathy-linked Alterations in Ca2+ Binding of Human Cardiac Myosin Regulatory Light Chain Affect Cardiac Muscle Contraction.

D. Szczesna-Cordary, G. Guzman, S.-S. Ng, and J. Zhao (2004)
J. Biol. Chem. 279, 3535-3542
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Evolutionary Convergence of the Flight Muscle Protein Arthrin in Diptera and Hemiptera.

S. Schmitz, C. J. Schankin, H. Prinz, R. S. Curwen, P. D. Ashton, L. S. D. Caves, R. H. A. Fink, J. C. Sparrow, P. J. Mayhew, and C. Veigel (2003)
Mol. Biol. Evol. 20, 2019-2033
 |  Abstract »  |  Full Text »  |  PDF »

Myosin light chain isoforms modify force-generating ability of cardiac myosin by changing the kinetics of actin-myosin interaction.

H. Yamashita, S. Sugiura, H. Fujita, S.-i. Yasuda, R. Nagai, Y. Saeki, K. Sunagawa, and H. Sugi (2003)
Cardiovasc Res 60, 580-588
 |  Abstract »  |  Full Text »  |  PDF »

Mutations in the motor domain modulate myosin activity and myofibril organization.

Q. Wang, C. L. Moncman, and D. A. Winkelmann (2003)
J. Cell Sci. 116, 4227-4238
 |  Abstract »  |  Full Text »  |  PDF »

Cryo-atomic Force Microscopy of Unphosphorylated and Thiophosphorylated Single Smooth Muscle Myosin Molecules.

S. Sheng, Y. Gao, A. S. Khromov, A. V. Somlyo, A. P. Somlyo, and Z. Shao (2003)
J. Biol. Chem. 278, 39892-39896
 |  Abstract »  |  Full Text »  |  PDF »

Mutations of the {beta} myosin heavy chain gene in hypertrophic cardiomyopathy: critical functional sites determine prognosis.

A Woo, H Rakowski, J C Liew, M-S Zhao, C-C Liew, T G Parker, M Zeller, E D Wigle, and M J Sole (2003)
Heart 89, 1179-1185
 |  Abstract »  |  Full Text »  |  PDF »

Chemical Identification of Serine 181 at the ATP-binding Site of Myosin as a Residue Esterified Selectively by the Fluorescent Reagent 9-Anthroylnitrile.

T. Hiratsuka and T. Katoh (2003)
J. Biol. Chem. 278, 31891-31894
 |  Abstract »  |  Full Text »  |  PDF »

Two Functional Heads Are Required for Full Activation of Smooth Muscle Myosin.

X.-d. Li and M. Ikebe (2003)
J. Biol. Chem. 278, 29435-29441
 |  Abstract »  |  Full Text »  |  PDF »

A mutant heterodimeric myosin with one inactive head generates maximal displacement.

N. M. Kad, A. S. Rovner, P. M. Fagnant, P. B. Joel, G. G. Kennedy, J. B. Patlak, D. M. Warshaw, and K. M. Trybus (2003)
J. Cell Biol. 162, 481-488
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Mechanics and crossbridge kinetics of tracheal smooth muscle in two inbred rat strains.

F-X. Blanc, C. Coirault, S. Salmeron, D. Chemla, and Y. Lecarpentier (2003)
Eur. Respir. J. 22, 227-234
 |  Abstract »  |  Full Text »  |  PDF »

Roles of the Hydrophobic Triplet in the Motor Domain of Myosin in the Interaction between Myosin and Actin.

Y. Hachikubo, K. Ito, and K. Yamamoto (2003)
J. Biochem. 134, 165-171
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Effects of halogenated anaesthetics on diaphragmatic actin-myosin cross-bridge kinetics.

O. Langeron, B. Bouhemad, G. Orliaguet, P. Coriat, Y. Lecarpentier, and B. Riou (2003)
Br. J. Anaesth. 90, 759-765
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She4p/Dim1p Interacts with the Motor Domain of Unconventional Myosins in the Budding Yeast, Saccharomyces cerevisiae.

H. Toi, K. Fujimura-Kamada, K. Irie, Y. Takai, S. Todo, and K. Tanaka (2003)
Mol. Biol. Cell 14, 2237-2249
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Muscle Hypercontraction by Mutations in the Myosin Heavy Chain Gene of Drosophila melanogaster.

U. Nongthomba, M. Cummins, S. Clark, J. O. Vigoreaux, and J. C. Sparrow (2003)
Genetics 164, 209-222
 |  Abstract »  |  Full Text »  |  PDF »

Different degrees of lever arm rotation control myosin step size.

D. Kohler, C. Ruff, E. Meyhofer, and M. Bahler (2003)
J. Cell Biol. 161, 237-241
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The converter domain modulates kinetic properties of Drosophila myosin.

K. P. Littlefield, D. M. Swank, B. M. Sanchez, A. F. Knowles, D. M. Warshaw, and S. I. Bernstein (2003)
Am J Physiol Cell Physiol 284, C1031-C1038
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Myosin isoforms show unique conformations in the actin-bound state.

N. Volkmann, G. Ouyang, K. M. Trybus, D. J. DeRosier, S. Lowey, and D. Hanein (2003)
PNAS 100, 3227-3232
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Solution Structure of Heavy Meromyosin by Small-angle Scattering.

S. P. Harris, W. T. Heller, M. L. Greaser, R. L. Moss, and J. Trewhella (2003)
J. Biol. Chem. 278, 6034-6040
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The prepower stroke conformation of myosin V.

S. Burgess, M. Walker, F. Wang, J. R. Sellers, H. D. White, P. J. Knight, and J. Trinick (2002)
J. Cell Biol. 159, 983-991
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Early stages of energy transduction by myosin: Roles of Arg in Switch I, of Glu in Switch II, and of the salt-bridge between them.

H. Onishi, T. Ohki, N. Mochizuki, and M. F. Morales (2002)
PNAS 99, 15339-15344
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Maternal dexamethasone treatment alters myosin isoform expression and contractile dynamics in fetal arteries.

C.-M. Hai, G. Sadowska, L. Francois, and B. S. Stonestreet (2002)
Am J Physiol Heart Circ Physiol 283, H1743-H1749
 |  Abstract »  |  Full Text »  |  PDF »

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