Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 18 June 1993:
Vol. 260. no. 5115, pp. 1819 - 1821
DOI: 10.1126/science.8511592
Prev | Table of Contents | Next

Articles

Science, Vol 260, Issue 5115, 1819-1821
Copyright © 1993 by American Association for the Advancement of Science

articles

Rapid remodeling of axonal arbors in the visual cortex

A Antonini and MP Stryker

W. M. Keck Foundation Center for Integrative Neuroscience, Department of Physiology, University of California, San Francisco 94143.

If vision in one eye is blurred or occluded during a critical period in postnatal development, neurons in the visual cortex lose their responses to stimulation through that eye within a few days. Anatomical changes in the nerve terminals that provide input to the visual cortex have previously been observed only after weeks of deprivation, suggesting that synapses become physiologically ineffective before the branches on which they sit are withdrawn. Reconstruction of single geniculocortical axonal arbors in the cat after either brief or prolonged monocular occlusion revealed striking axonal rearrangements in both instances. Rapid withdrawal of the branches of deprived-eye arbors suggests that axonal branches bearing synapses respond quickly to changing patterns of neuronal activity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Interareal coordination of columnar architectures during visual cortical development.
M. Kaschube, M. Schnabel, F. Wolf, and S. Lowel (2009)
PNAS 106, 17205-17210
   Abstract »    Full Text »    PDF »
Co-regulation of ocular dominance plasticity and NMDA receptor subunit expression in glutamic acid decarboxylase-65 knock-out mice.
P. O. Kanold, Y. A. Kim, T. GrandPre, and C. J. Shatz (2009)
J. Physiol. 587, 2857-2867
   Abstract »    Full Text »    PDF »
Early Withdrawal of Axons from Higher Centers in Response to Peripheral Somatosensory Denervation.
A. Graziano and E. G. Jones (2009)
J. Neurosci. 29, 3738-3748
   Abstract »    Full Text »    PDF »
Sensory Experience Alters Specific Branches of Individual Corticocortical Axons during Development.
R. M. Bruno, T. T. G. Hahn, D. J. Wallace, C. P. J. de Kock, and B. Sakmann (2009)
J. Neurosci. 29, 3172-3181
   Abstract »    Full Text »    PDF »
Molecular mechanisms of experience-dependent plasticity in visual cortex.
D. Tropea, A. Van Wart, and M. Sur (2009)
Phil Trans R Soc B 364, 341-355
   Abstract »    Full Text »    PDF »
Role of RhoA in Activity-Dependent Cortical Axon Branching.
S. Ohnami, M. Endo, S. Hirai, N. Uesaka, Y. Hatanaka, T. Yamashita, and N. Yamamoto (2008)
J. Neurosci. 28, 9117-9121
   Abstract »    Full Text »    PDF »
Activity-Dependent Thalamocortical Axon Branching.
Y. Hayano and N. Yamamoto (2008)
Neuroscientist 14, 359-368
   Abstract »    PDF »
Critical Period Plasticity of Axonal Arbors of Layer 2/3 Pyramidal Neurons in Rat Somatosensory Cortex: Layer-Specific Reduction of Projections into Deprived Cortical Columns.
P. Broser, V. Grinevich, P. Osten, B. Sakmann, and D. J. Wallace (2008)
Cereb Cortex 18, 1588-1603
   Abstract »    Full Text »    PDF »
Pioneers of cortical plasticity: six classic papers by Wiesel and Hubel.
M. Constantine-Paton (2008)
J Neurophysiol 99, 2741-2744
   Abstract »    Full Text »    PDF »
Plasticity of Representational Maps in Somatosensory Cortex Observed by In Vivo Voltage-Sensitive Dye Imaging.
D. J. Wallace and B. Sakmann (2008)
Cereb Cortex 18, 1361-1373
   Abstract »    Full Text »    PDF »
Vision Triggers an Experience-Dependent Sensitive Period at the Retinogeniculate Synapse.
B. M. Hooks and C. Chen (2008)
J. Neurosci. 28, 4807-4817
   Abstract »    Full Text »    PDF »
Synapse elimination accompanies functional plasticity in hippocampal neurons.
N. Bastrikova, G. A. Gardner, J. M. Reece, A. Jeromin, and S. M. Dudek (2008)
PNAS 105, 3123-3127
   Abstract »    Full Text »    PDF »
Evidence for Activity-Dependent Cortical Wiring: Formation of Interhemispheric Connections in Neonatal Mouse Visual Cortex Requires Projection Neuron Activity.
H. Mizuno, T. Hirano, and Y. Tagawa (2007)
J. Neurosci. 27, 6760-6770
   Abstract »    Full Text »    PDF »
Visual Cortical Recovery From Reverse Occlusion Depends on Concordant Binocular Experience.
S. D. Faulkner, V. Vorobyov, and F. Sengpiel (2006)
J Neurophysiol 95, 1718-1726
   Abstract »    Full Text »    PDF »
Patterning and Plasticity of the Cerebral Cortex.
M. Sur and J. L. R. Rubenstein (2005)
Science 310, 805-810
   Abstract »    Full Text »    PDF »
Limited Protection of the Primary Visual Cortex from the Effects of Monocular Deprivation by Strabismus.
S. D. Faulkner, V. Vorobyov, and F. Sengpiel (2005)
Cereb Cortex 15, 1822-1833
   Abstract »    Full Text »    PDF »
Experience-Dependent Plasticity in S1 Caused by Noncoincident Inputs.
D. T. Blake, F. Strata, R. Kempter, and M. M. Merzenich (2005)
J Neurophysiol 94, 2239-2250
   Abstract »    Full Text »    PDF »
Loss of Neurofilament Labeling in the Primary Visual Cortex of Monocularly Deprived Monkeys.
K. R. Duffy and M. S. Livingstone (2005)
Cereb Cortex 15, 1146-1154
   Abstract »    Full Text »    PDF »
Substrates for Coincidence Detection and Calcium Signaling for Induction of Synaptic Potentiation in the Neonatal Visual Cortex.
L. A. Schrader, S. P. Perrett, L. Ye, and M. J. Friedlander (2004)
J Neurophysiol 91, 2747-2764
   Abstract »    Full Text »    PDF »
Motility of dendritic spines in visual cortex in vivo: Changes during the critical period and effects of visual deprivation.
A. Majewska and M. Sur (2003)
PNAS 100, 16024-16029
   Abstract »    Full Text »    PDF »
Blockade of Cyclic AMP-Dependent Protein Kinase Does Not Prevent the Reverse Ocular Dominance Shift in Kitten Visual Cortex.
S. Shimegi, Q. S. Fischer, Y. Yang, H. Sato, and N. W. Daw (2003)
J Neurophysiol 90, 4027-4032
   Abstract »    Full Text »    PDF »
Development of Columnar Topography in the Excitatory Layer 4 to Layer 2/3 Projection in Rat Barrel Cortex.
K. J. Bender, J. Rangel, and D. E. Feldman (2003)
J. Neurosci. 23, 8759-8770
   Abstract »    Full Text »    PDF »
Roles of Protein Kinase A and Protein Kinase G in Synaptic Plasticity in the Visual Cortex.
S. Liu, Y. Rao, and N. Daw (2003)
Cereb Cortex 13, 864-869
   Abstract »    Full Text »    PDF »
Anatomical organization of forward fiber projections from area TE to perirhinal neurons representing visual long-term memory in monkeys.
M. Yoshida, Y. Naya, and Y. Miyashita (2003)
PNAS 100, 4257-4262
   Abstract »    Full Text »    PDF »
The Developing Synapse: Construction and Modulation of Synaptic Structures and Circuits.
S. Cohen-Cory (2002)
Science 298, 770-776
   Abstract »    Full Text »    PDF »
Spatial Analysis of Ocular Dominance Patterns in Monocularly Deprived Cats.
K. E. Schmidt, M. Stephan, W. Singer, and S. Lowel (2002)
Cereb Cortex 12, 783-796
   Abstract »    Full Text »    PDF »
Physiological Correlates of Perceptual Learning in Monkey V1 and V2.
G. M. Ghose, T. Yang, and J. H. R. Maunsell (2002)
J Neurophysiol 87, 1867-1888
   Abstract »    Full Text »    PDF »
Effects of Reversible Inactivation of the Neonatal Ventral Hippocampus on Behavior in the Adult Rat.
B. K. Lipska, N. D. Halim, P. N. Segal, and D. R. Weinberger (2002)
J. Neurosci. 22, 2835-2842
   Abstract »    Full Text »    PDF »
Experience-Dependent Plasticity of Mouse Visual Cortex in the Absence of the Neuronal Activity-Dependent Marker egr1/zif268.
N. Mataga, S. Fujishima, B. G. Condie, and T. K. Hensch (2001)
J. Neurosci. 21, 9724-9732
   Abstract »    Full Text »    PDF »
Initial recovery of vision after early monocular deprivation in kittens is faster when both eyes are open.
D. E. Mitchell, G. Gingras, and P. C. Kind (2001)
PNAS 98, 11662-11667
   Abstract »    Full Text »    PDF »
Rapid Anatomical Plasticity of Horizontal Connections in the Developing Visual Cortex.
J. T. Trachtenberg and M. P. Stryker (2001)
J. Neurosci. 21, 3476-3482
   Abstract »    Full Text »    PDF »
Adaptive Axonal Remodeling in the Midbrain Auditory Space Map.
W. M. DeBello, D. E. Feldman, and E. I. Knudsen (2001)
J. Neurosci. 21, 3161-3174
   Abstract »    Full Text »    PDF »
Imaging High-Resolution Structure of GFP-Expressing Neurons in Neocortex In Vivo.
B. E. Chen, B. Lendvai, E. A. Nimchinsky, B. Burbach, K. Fox, and K. Svoboda (2000)
Learn. Mem. 7, 433-441
   Abstract »    Full Text »
The Development of Abnormal Axon Trajectories after Rotation of One Eye in Xenopus.
Y. Guo and S. B. Udin (2000)
J. Neurosci. 20, 4189-4197
   Abstract »    Full Text »    PDF »
Progressive Transneuronal Changes in the Brainstem and Thalamus after Long-Term Dorsal Rhizotomies in Adult Macaque Monkeys.
T. M. Woods, C. G. Cusick, T. P. Pons, E. Taub, and E. G. Jones (2000)
J. Neurosci. 20, 3884-3899
   Abstract »    Full Text »    PDF »
Cortical Cell Orientation Selectivity Fails to Develop in the Absence of ON-Center Retinal Ganglion Cell Activity.
B. Chapman and I. Godecke (2000)
J. Neurosci. 20, 1922-1930
   Abstract »    Full Text »    PDF »
Rapid Regulation of Brain-Derived Neurotrophic Factor mRNA within Eye-Specific Circuits during Ocular Dominance Column Formation.
E. S. Lein and C. J. Shatz (2000)
J. Neurosci. 20, 1470-1483
   Abstract »    Full Text »    PDF »
Synaptic Density in Geniculocortical Afferents Remains Constant after Monocular Deprivation in the Cat.
M. A. Silver and M. P. Stryker (1999)
J. Neurosci. 19, 10829-10842
   Abstract »    Full Text »    PDF »
Rapid Improvement in the Acuity of Infants After Visual Input.
D. Maurer, T. L. Lewis, H. P. Brent, and A. V. Levin (1999)
Science 286, 108-110
   Abstract »    Full Text »
The Critical Period for Ocular Dominance Plasticity in the Ferret's Visual Cortex.
N. P. Issa, J. T. Trachtenberg, B. Chapman, K. R. Zahs, and M. P. Stryker (1999)
J. Neurosci. 19, 6965-6978
   Abstract »    Full Text »    PDF »
A Changing Pattern of Brain-Derived Neurotrophic Factor Expression Correlates with the Rearrangement of Fibers during Cochlear Development of Rats and Mice.
B. Wiechers, G. Gestwa, A. Mack, P. Carroll, H.-P. Zenner, and M. Knipper (1999)
J. Neurosci. 19, 3033-3042
   Abstract »    Full Text »    PDF »
Sensory Regulation of Immediate-early Genes c-fos and zif268 in Monkey Visual Cortex at Birth and Throughout the Critical Period.
L. Kaczmarek, S. Zangenehpour, and A. Chaudhuri (1999)
Cereb Cortex 9, 179-187
   Abstract »    Full Text »    PDF »
Morphology of Single Geniculocortical Afferents and Functional Recovery of the Visual Cortex after Reverse Monocular Deprivation in the Kitten.
A. Antonini, D. C. Gillespie, M. C. Crair, and M. P. Stryker (1998)
J. Neurosci. 18, 9896-9909
   Abstract »    Full Text »    PDF »
Local GABA Circuit Control of Experience-Dependent Plasticity in Developing Visual Cortex.
T. K. Hensch, M. Fagiolini, N. Mataga, M. P. Stryker, S. Baekkeskov, and S. F. Kash (1998)
Science 282, 1504-1508
   Abstract »    Full Text »
Patchy Distribution of NMDAR1 Subunit Immunoreactivity in Developing Visual Cortex.
C. Trepel, K. R. Duffy, V. D. Pegado, and K. M. Murphy (1998)
J. Neurosci. 18, 3404-3415
   Abstract »    Full Text »    PDF »
Differential Effects of Abnormal Tactile Experience on Shaping Representation Patterns in Developing and Adult Motor Cortex.
G. W. Huntley (1997)
J. Neurosci. 17, 9220-9232
   Abstract »    Full Text »    PDF »
Activity-Dependent Regulation of NMDAR1 Immunoreactivity in the Developing Visual Cortex.
S. M. Catalano, C. K. Chang, and C. J. Shatz (1997)
J. Neurosci. 17, 8376-8390
   Abstract »    Full Text »    PDF »
An Anatomical Basis for Visual Calibration of the Auditory Space Map in the Barn Owl's Midbrain.
D. E. Feldman and E. I. Knudsen (1997)
J. Neurosci. 17, 6820-6837
   Abstract »    Full Text »    PDF »
Anterior Forebrain Neurons Develop Selectivity by an Intermediate Stage of Birdsong Learning.
M. M. Solis and A. J. Doupe (1997)
J. Neurosci. 17, 6447-6462
   Abstract »    Full Text »    PDF »
Timing of the Critical Period for Plasticity of Ocular Dominance Columns in Macaque Striate Cortex.
J. C. Horton and D. R. Hocking (1997)
J. Neurosci. 17, 3684-3709
   Abstract »    Full Text »    PDF »
Transient Synaptic Potentiation in the Visual Cortex. II. Developmental Regulation.
K. Harsanyi and M. J. Friedlander (1997)
J Neurophysiol 77, 1284-1293
   Abstract »    Full Text »    PDF »
Phospholipase C-beta 1 Is Present in the Botrysome, an Intermediate Compartment-Like Organelle, and Is Regulated by Visual Experience in Cat Visual Cortex.
P. C. Kind, G. M. Kelly, H. J. L. Fryer, C. Blakemore, and S. Hockfield (1997)
J. Neurosci. 17, 1471-1480
   Abstract »    Full Text »    PDF »
cAMP Levels Increased by Activation of Metabotropic Glutamate Receptors Correlate with Visual Plasticity.
S. N. M. Reid, N. W. Daw, D. S. Gregory, and H. Flavin (1996)
J. Neurosci. 16, 7619-7626
   Abstract »    Full Text »    PDF »
Development of Orientation Preference Maps in Ferret Primary Visual Cortex.
B. Chapman, M. P. Stryker, and T. Bonhoeffer (1996)
J. Neurosci. 16, 6443-6453
   Abstract »    Full Text »    PDF »
Experience-Dependent Plasticity of Binocular Responses in the Primary Visual Cortex of the Mouse.
J. A. Gordon and M. P. Stryker (1996)
J. Neurosci. 16, 3274-3286
   Abstract »    Full Text »    PDF »
In Vivo Development of Neuronal Structure and Function.
H.T. Cline, G.-Y. Wu, and R. Malinow (1996)
Cold Spring Harb Symp Quant Biol 61, 95-104
   Abstract »    PDF »
Mutagenesis of apobec-1, the Catalytic Subunit of the Mammalian Apolipoprotein B mRNA Editing Enzyme, Reveals Distinct Domains That Mediate Cytosine Nucleoside Deaminase, RNA Binding, and RNA Editing Activity.
A. J. MacGinnitie, S. Anant, and N. O. Davidson (1995)
J. Biol. Chem. 270, 14768-14775
   Abstract »    Full Text »    PDF »
Rearrangements of synaptic connections in visual cortex revealed by laser photostimulation.
M. Dalva and L. Katz (1994)
Science 265, 255-258
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)