Science 11 June 1993: Vol. 260. no. 5114, pp. 1655 - 1658 DOI: 10.1126/science.8503012

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Articles

Novel markers of peripheral arterial disease.

F. J Khawaja and I. J Kullo (2009)
Vascular Medicine 14, 381-392
 |  Abstract »  |  PDF »

TGF-{beta} and atherosclerosis in man.

D. J. Grainger (2007)
Cardiovasc Res 74, 213-222
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Relation Between Lipoprotein(a) and Fibrinogen and Serial Intravascular Ultrasound Plaque Progression in Left Main Coronary Arteries.

M. Hartmann, C. von Birgelen, G. S. Mintz, M. G. Stoel, H. Eggebrecht, H. Wieneke, M. Fahy, T. Neumann, J. van der Palen, H. W. Louwerenburg, et al. (2006)
J. Am. Coll. Cardiol. 48, 446-452
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TGF-{beta} impairs renal autoregulation via generation of ROS.

K. Sharma, A. Cook, M. Smith, C. Valancius, and E. W. Inscho (2005)
Am J Physiol Renal Physiol 288, F1069-F1077
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Conditional Risk Factors for Atherosclerosis.

I. J. Kullo and C. M. Ballantyne (2005)
Mayo Clin. Proc. 80, 219-230
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Stimulation of Vascular Smooth Muscle Cell Proliferation and Migration by Apolipoprotein(a) Is Dependent on Inhibition of Transforming Growth Factor-{beta} Activation and on the Presence of Kringle IV Type 9.

C. H. O'Neil, M. B. Boffa, M. A. Hancock, J. G. Pickering, and M. L. Koschinsky (2004)
J. Biol. Chem. 279, 55187-55195
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Lack of Association Between Lipoprotein(a) and Coronary Artery Calcification in the Genetic Epidemiology Network of Arteriopathy (GENOA) Study.

I. J. Kullo, K. R. Bailey, L. F. Bielak, P. F. Sheedy II, G. G. Klee, S. L. Kardia, P. A. Peyser, E. Boerwinkle, and S. T. Turner (2004)
Mayo Clin. Proc. 79, 1258-1263
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Transforming Growth Factor {beta} and Atherosclerosis: So Far, So Good for the Protective Cytokine Hypothesis.

D. J. Grainger (2004)
Arterioscler Thromb Vasc Biol 24, 399-404
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The Apolipoprotein(a) Component of Lipoprotein(a) Stimulates Actin Stress Fiber Formation and Loss of Cell-Cell Contact in Cultured Endothelial Cells.

M. Pellegrino, E. Furmaniak-Kazmierczak, J. C. LeBlanc, T. Cho, K. Cao, S. M. Marcovina, M. B. Boffa, G. P. Cote, and M. L. Koschinsky (2004)
J. Biol. Chem. 279, 6526-6533
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Involvement of transforming growth factor-{beta} in regulation of calcium transients in diabetic vascular smooth muscle cells.

K. Sharma, L. Deelman, M. Madesh, B. Kurz, E. Ciccone, S. Siva, T. Hu, Y. Zhu, L. Wang, R. Henning, et al. (2003)
Am J Physiol Renal Physiol 285, F1258-F1270
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Prediction of Short-Term Progression or Regression of Atherosclerotic Coronary Artery Disease by Lipoprotein (a): A Quantitative Coronary Angiographic Study.

T. Uchida, T. Inoue, H. Kamishirado, K. Takayanagi, and S. Morooka (2003)
Angiology 54, 641-646
 |  Abstract »  |  PDF »

Effect of Aspirin Treatment on Serum Concentrations of Lipoprotein(a) in Patients with Atherosclerotic Diseases.

M. Akaike, H. Azuma, A. Kagawa, K. Matsumoto, I. Hayashi, K. Tamura, T. Nishiuchi, T. Iuchi, N. Takamori, K.-i. Aihara, et al. (2002)
Clin. Chem. 48, 1454-1459
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Mitogenic Activity of Oxidized Lipoprotein (a) on Human Vascular Smooth Muscle Cells.

N. Komai, R. Morishita, S. Yamada, M. Oishi, S. Iguchi, M. Aoki, M. Sasaki, I. Sakurabayashi, J. Higaki, and T. Ogihara (2002)
Hypertension 40, 310-314
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Lipoprotein(a) Promotes Smooth Muscle Cell Proliferation and Dedifferentiation in Atherosclerotic Lesions of Human Apo(a) Transgenic Rabbits.

T. Ichikawa, H. Unoki, H. Sun, H. Shimoyamada, S. Marcovina, H. Shikama, T. Watanabe, and J. Fan (2002)
Am. J. Pathol. 160, 227-236
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Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis.

N. M. Caplice, C. Panetta, T. E. Peterson, L. S. Kleppe, C. S. Mueske, G. M. Kostner, G. J. Broze Jr, and R. D. Simari (2001)
Blood 98, 2980-2987
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Role of Lipoprotein (a) and TGF-{beta}1 in Atherosclerosis of Hemodialysis Patients.

M. FUJISAWA, R. HARAMAKI, H. MIYAZAKI, T. IMAIZUMI, and S. OKUDA (2000)
J. Am. Soc. Nephrol. 11, 1889-1895
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Association of a T29->C Polymorphism of the Transforming Growth Factor-{beta}1 Gene With Genetic Susceptibility to Myocardial Infarction in Japanese.

M. Yokota, S. Ichihara, T.-L. Lin, N. Nakashima, and Y. Yamada (2000)
Circulation 101, 2783-2787
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Cardiovascular Overexpression of Transforming Growth Factor-{beta}1 Causes Abnormal Yolk Sac Vasculogenesis and Early Embryonic Death.

R. Agah, K. S. S. Prasad, R. Linnemann, M. T. Firpo, T. Quertermous, and D. A. Dichek (2000)
Circ. Res. 86, 1024-1030
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Enzymatically Degraded, Nonoxidized LDL Induces Human Vascular Smooth Muscle Cell Activation, Foam Cell Transformation, and Proliferation.

M. Klouche, S. Rose-John, W. Schmiedt, and S. Bhakdi (2000)
Circulation 101, 1799-1805
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Dietary fat and reduced levels of TGFbeta1 act synergistically to promote activation of the vascular endothelium and formation of lipid lesions.

D. Grainger, D. Mosedale, J. Metcalfe, and E. Bottinger (2000)
J. Cell Sci. 113, 2355-2361
 |  Abstract »  |  PDF »

Aspirin Reduces Apolipoprotein(a) (Apo(a)) Production in Human Hepatocytes by Suppression of Apo(a) Gene Transcription.

A. Kagawa, H. Azuma, M. Akaike, Y. Kanagawa, and T. Matsumoto (1999)
J. Biol. Chem. 274, 34111-34115
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Editorials: Lipids and coronary restenosis: an elusive link.

P.J. de Feyter (1999)
Eur. Heart J. 20, 1371-1374
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Luminal loss and restenosis after coronary angioplasty. The role of lipoproteins and lipids.

B Jorgensen, S Simonsen, K Endresen, K Forfang, T Egeland, A.T Hostmark, and E Thaulow (1999)
Eur. Heart J. 20, 1407-1414
 |  Abstract »  |  PDF »

Role of Lipoprotein(a) and Apolipoprotein(a) Phenotype in Atherogenesis : Prospective Results From the Bruneck Study.

F. Kronenberg, M. F. Kronenberg, S. Kiechl, E. Trenkwalder, P. Santer, F. Oberhollenzer, G. Egger, G. Utermann, and J. Willeit (1999)
Circulation 100, 1154-1160
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Potential New Cardiovascular Risk Factors: Left Ventricular Hypertrophy, Homocysteine, Lipoprotein(a), Triglycerides, Oxidative Stress, and Fibrinogen.

K. J. Harjai (1999)
Ann Intern Med 131, 376-386
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Evaluation of Genetic Risk Factors for Silent Brain Infarction.

Y. Notsu, T. Nabika, H.-Y. Park, J. Masuda, and S. Kobayashi (1999)
Stroke 30, 1881-1886
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Estrogen Modulation of Apolipoprotein(a) Expression. IDENTIFICATION OF A REGULATORY ELEMENT.

D. Boffelli, D. A. Zajchowski, Z. Yang, and R. M. Lawn (1999)
J. Biol. Chem. 274, 15569-15574
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Effect of Lp(a) on the Early Functional and Structural Changes of Atherosclerosis.

O. T. Raitakari, M. R. Adams, and D. S. Celermajer (1999)
Arterioscler Thromb Vasc Biol 19, 990-995
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Lipoprotein(a) and coronary thrombosis and restenosis after stent placement.

A. Wehinger, A. Kastrati, S. Elezi, H. Baum, S. Braun, F.-J. Neumann, and A. Schomig (1999)
J. Am. Coll. Cardiol. 33, 1005-1012
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Detection of the `4977 bp' mitochondrial DNA deletion in human atherosclerotic lesions.

M. Bogliolo, A. Izzotti, S. De Flora, C. Carli, A. Abbondandolo, and P. Degan (1999)
Mutagenesis 14, 77-82
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Lipoprotein(a) and inflammation in human coronary atheroma: association with the severity of clinical presentation.

G. Dangas, R. Mehran, P. C. Harpel, S. K. Sharma, S. M. Marcovina, G. Dube, J. A. Ambrose, and J. T. Fallon (1998)
J. Am. Coll. Cardiol. 32, 2035-2042
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Expression of adhesion molecules by Lp(a): a potential novel mechanism for its atherogenicity.

S. Allen, S. Khan, S.-p. Tam, M. Koschinsky, P. Taylor, and M. Yacoub (1998)
FASEB J 12, 1765-1776
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Novel Therapeutic Strategy for Atherosclerosis : Ribozyme Oligonucleotides Against Apolipoprotein(a) Selectively Inhibit Apolipoprotein(a) But Not Plasminogen Gene Expression.

R. Morishita, S. Yamada, K. Yamamoto, N. Tomita, I. Kida, I. Sakurabayashi, A. Kikuchi, Y. Kaneda, R. Lawn, J. Higaki, et al. (1998)
Circulation 98, 1898-1904
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Putative susceptibility markers of coronary artery disease: association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue.

F. J. Van schooten, A. Hirvonen, L. M. Maas, B. A. De mol, J. C. S. kleinjans, D. A. Bell, and J. D. Durrer (1998)
FASEB J 12, 1409-1417
 |  Abstract »  |  Full Text »

Plasma Lipoprotein(a) Is Not a Predictor for Restenosis After Elective High-Pressure Coronary Stenting.

F. Ribichini, G. Steffenino, A. Dellavalle, A. Vado, V. Ferrero, T. Camilla, S. Giubergia, and E. Uslenghi (1998)
Circulation 98, 1172-1177
 |  Abstract »  |  Full Text »  |  PDF »

Immune Sources of Transforming Growth Factor-ß1 Reduce Transplant Arteriosclerosis : Insight Derived From a Knockout Mouse Model.

J. Koglin, T. Glysing-Jensen, A. Raisanen-Sokolowski, and M. E. Russell (1998)
Circ. Res. 83, 652-660
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Factor XIIIa Cross-links Lipoprotein(a) With Fibrinogen and Is Present in Human Atherosclerotic Lesions.

A. M. Romanic, A. J. Arleth, R. N. Willette, and E. H. Ohlstein (1998)
Circ. Res. 83, 264-269
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Conditioned Medium From HepG2 Cells Transfected With Human Apolipoprotein(a) Gene Stimulates Growth of Human Vascular Smooth Muscle Cells : Effects of Overexpression of Human Apolipoprotein(a) Gene.

R. Morishita, S. Yamada, J. Higaki, N. Tomita, I. Kida, M. Aoki, A. Moriguchi, S.-i. Hayashi, I. Sakurabayashi, Y. Kaneda, et al. (1998)
Hypertension 32, 215-222
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of transforming growth factor beta 1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia.

A. H. Schulick, A. J. Taylor, W. Zuo, C.-b. Qiu, G. Dong, R. N. Woodward, R. Agah, A. B. Roberts, R. Virmani, and D. A. Dichek (1998)
PNAS 95, 6983-6988
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Increased Degradation of Lipoprotein(a) in Atherosclerotic Compared With Nonlesioned Aortic Intima–Inner Media of Rabbits : In Vivo Evidence That Lipoprotein(a) May Contribute to Foam Cell Formation.

L. B. Nielsen, K. Juul, and B. G. Nordestgaard (1998)
Arterioscler Thromb Vasc Biol 18, 641-649
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Alcohol Withdrawal–Induced Change in Lipoprotein(a) : Association With the Growth Hormone/Insulin-like Growth Factor-I (IGF-I)/IGF-Binding Protein-1 (IGFBP-1) Axis.

M. Paassilta, K. Kervinen, M. Linnaluoto, and Y. A. Kesaniemi (1998)
Arterioscler Thromb Vasc Biol 18, 650-654
 |  Abstract »  |  Full Text »  |  PDF »

Lipoprotein(a) Enhances the Expression of Intercellular Adhesion Molecule-1 in Cultured Human Umbilical Vein Endothelial Cells.

S. Takami, S. Yamashita, S. Kihara, M. Ishigami, K. Takemura, N. Kume, T. Kita, and Y. Matsuzawa (1998)
Circulation 97, 721-728
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Modulation of Growth Factor Action : Implications for the Treatment of Cardiovascular Diseases.

J. Waltenberger (1997)
Circulation 96, 4083-4094
 |  Abstract »  |  Full Text »

Monounsaturated and Polyunsaturated n-6 Fatty Acid–Enriched Diets Modify LDL Oxidation and Decrease Human Coronary Smooth Muscle Cell DNA Synthesis.

P. Mata, O. Varela, R. Alonso, C. Lahoz, M. de Oya, and L. Badimon (1997)
Arterioscler Thromb Vasc Biol 17, 2088-2095
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Plasminogen deficiency accelerates vessel wall disease in mice predisposed to atherosclerosis.

Q. Xiao, M. J. S. Danton, D. P. Witte, M. C. Kowala, M. T. Valentine, T. H. Bugge, and J. L. Degen (1997)
PNAS 94, 10335-10340
 |  Abstract »  |  Full Text »  |  PDF »

Apolipoprotein(a) Attenuates Endogenous Fibrinolysis in the Rabbit Jugular Vein Thrombosis Model In Vivo.

B. J. Biemond, P. W. Friederich, M. L. Koschinsky, M. Levi, W. Sangrar, J. Xia, H. R. Buller, and J. W. t. Cate (1997)
Circulation 96, 1612-1615
 |  Abstract »  |  Full Text »

Novel Interaction of Apolipoprotein(a) With beta -2 Glycoprotein I Mediated by the Kringle IV Domain.

S. Kochl, F. Fresser, E. Lobentanz, G. Baier, and G. Utermann (1997)
Blood 90, 1482-1489
 |  Abstract »  |  Full Text »  |  PDF »

Defensin Stimulates the Binding of Lipoprotein (a) to Human Vascular Endothelial and Smooth Muscle Cells.

A. A.-R. Higazi, E. Lavi, K. Bdeir, A. M. Ulrich, D. G. Jamieson, D. J. Rader, D. C. Usher, W. Kane, T. Ganz, and D. B. Cines (1997)
Blood 89, 4290-4298
 |  Abstract »  |  Full Text »  |  PDF »

Association of Serum Lipoprotein(a) Levels and Apolipoprotein(a) Size Polymorphism With Target-Organ Damage in Arterial Hypertension.

L. A. Sechi, F. Kronenberg, S. De Carli, E. Falleti, L. Zingaro, C. Catena, G. Utermann, and E. Bartoli (1997)
JAMA 277, 1689-1695
 |  Abstract »  |  PDF »

In Vivo Transfer of Lipoprotein(a) Into Human Atherosclerotic Carotid Arterial Intima.

L. B. Nielsen, M. L.M. Gronholdt, T. V. Schroeder, S. Stender, and B. G. Nordestgaard (1997)
Arterioscler Thromb Vasc Biol 17, 905-911
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Localization of Lipoprotein(a) in a Monkey Model of Rapid Neointimal Growth.

M. J. Ryan, L. L. Emig, G. W. Hicks, R. Ramharack, M. A. Spahr, J. S. Kreick, D. W. Brammer, A. J. Chien, and J. A. Keiser (1997)
Arterioscler Thromb Vasc Biol 17, 181-187
 |  Abstract »  |  Full Text »

The Binding Activity of the Macrophage Lipoprotein(a)/Apolipoprotein(a) Receptor Is Induced by Cholesterol via a Post-translational Mechanism and Recognizes Distinct Kringle Domains on Apolipoprotein(a).

G. A. Keesler, B. R. Gabel, C. M. Devlin, M. L. Koschinsky, and I. Tabas (1996)
J. Biol. Chem. 271, 32096-32104
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Feedback Mechanism of Focal Vascular Lesion Formation in Transgenic Apolipoprotein(a) Mice.

R. M. Lawn, A. D. Pearle, L. L. Kunz, E. M. Rubin, J. Reckless, J. C. Metcalfe, and D. J. Grainger (1996)
J. Biol. Chem. 271, 31367-31371
 |  Abstract »  |  Full Text »  |  PDF »

Peripheral Blood Mononuclear Phagocyte Subpopulations as Cellular Markers in Hypercholesterolemia.

G. Rothe, H. Gabriel, E. Kovacs, J. Klucken, J. Stohr, W. Kindermann, and G. Schmitz (1996)
Arterioscler Thromb Vasc Biol 16, 1437-1447
 |  Abstract »  |  Full Text »

Induction of Hepatic Uptake of Lipoprotein(a) by Cholesterol-Derivatized Cluster Galactosides.

E. A.L. Biessen, H. Vietsch, and T. J.C. van Berkel (1996)
Arterioscler Thromb Vasc Biol 16, 1552-1558
 |  Abstract »  |  Full Text »

Polymorphisms of the Transforming Growth Factor-ß1 Gene in Relation to Myocardial Infarction and Blood Pressure: The Etude Cas-Temoin de l'Infarctus du Myocarde (ECTIM) Study.

F. Cambien, S. Ricard, A. Troesch, C. Mallet, L. Generenaz, A. Evans, D. Arveiler, G. Luc, J.-B. Ruidavets, and O. Poirier (1996)
Hypertension 28, 881-887
 |  Abstract »  |  Full Text »

Contrasting Effects of Plasminogen Activators, Urokinase Receptor, and LDL Receptor–Related Protein on Smooth Muscle Cell Migration and Invasion.

S. S. Okada, S. R. Grobmyer, and E. S. Barnathan (1996)
Arterioscler Thromb Vasc Biol 16, 1269-1276
 |  Abstract »  |  Full Text »

Beyond Low-Density Lipoprotein Cholesterol: A Perspective on Low High-Density Lipoprotein Disorders and Lp(a) Lipoprotein Excess.

R. S. Rosenson (1996)
Arch Intern Med 156, 1278-1284
 |  Abstract »  |  PDF »

Apolipoprotein(a) Kringle IV Repeat Number Predicts Risk for Coronary Heart Disease.

H.G. Kraft, A. Lingenhel, S. Kochl, F. Hoppichler, F. Kronenberg, A. Abe, V. Muhlberger, D. Schonitzer, and G. Utermann (1996)
Arterioscler Thromb Vasc Biol 16, 713-719
 |  Abstract »  |  Full Text »

Specific Accumulation of Lipoprotein(a) in Balloon-Injured Rabbit Aorta In Vivo.

L. B. Nielsen, S. Stender, K. Kjeldsen, and B. G. Nordestgaard (1996)
Circ. Res. 78, 615-626
 |  Abstract »  |  Full Text »

Migration of Arterial Wall Cells : Expression of Plasminogen Activators and Inhibitors in Injured Rat Arteries.

M. A. Reidy, C. Irvin, and V. Lindner (1996)
Circ. Res. 78, 405-414
 |  Abstract »  |  Full Text »

Characterization of the Promoter Region of the Human Transforming Growth Factor-beta Type II Receptor Gene.

H. W. Bae, A. G. Geiser, D. H. Kim, M. T. Chung, J. K. Burmester, M. B. Sporn, A. B. Roberts, and S.-J. Kim (1995)
J. Biol. Chem. 270, 29460-29468
 |  Abstract »  |  Full Text »  |  PDF »

Relative Contributions of Apolipoprotein(a) and Apolipoprotein-B to the Development of Fatty Lesions in the Proximal Aorta of Mice.

F.P. Mancini, D.L. Newland, V. Mooser, J. Murata, S. Marcovina, S.G. Young, R.E. Hammer, D.A. Sanan, and H.H. Hobbs (1995)
Arterioscler Thromb Vasc Biol 15, 1911-1916
 |  Abstract »  |  Full Text »

The Recurring Evolution of Lipoprotein(a).

R. M. Lawn, N. W. Boonmark, K. Schwartz, G. E. Lindahl, D. P. Wade, C. D. Byrne, K. J. Fong, K. Meer, and L. Patthy (1995)
J. Biol. Chem. 270, 24004-24009
 |  Abstract »  |  Full Text »  |  PDF »

Plasminogen Activator System in Human Coronary Atherosclerosis.

P.N. Raghunath, J. E. Tomaszewski, S. T. Brady, R. J. Caron, S. S. Okada, and E. S. Barnathan (1995)
Arterioscler Thromb Vasc Biol 15, 1432-1443
 |  Abstract »  |  Full Text »

The Intima : Soil for Atherosclerosis and Restenosis.

S. M. Schwartz, D. deBlois, and E. R. M. O'Brien (1995)
Circ. Res. 77, 445-465
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TGF-ß and Endothelial Cells Inhibit VCAM-1 Expression on Human Vascular Smooth Muscle Cells.

J. R. Gamble, S. Bradley, L. Noack, and M. A. Vadas (1995)
Arterioscler Thromb Vasc Biol 15, 949-955
 |  Abstract »  |  Full Text »

The Response-to-Retention Hypothesis of Early Atherogenesis.

K. J. Williams and I. Tabas (1995)
Arterioscler Thromb Vasc Biol 15, 551-561
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Rapamycin-FKBP Inhibits Cell Cycle Regulators of Proliferation in Vascular Smooth Muscle Cells.

S. O. Marx, T. Jayaraman, L. O. Go, and A. R. Marks (1995)
Circ. Res. 76, 412-417
 |  Abstract »  |  Full Text »

Elevated Serum Lipoprotein(a) Is a Risk Factor for Clinical Recurrence After Coronary Balloon Angioplasty.

R. L. Desmarais, I. J. Sarembock, C. R. Ayers, S. M. Vernon, E. R. Powers, and L. W. Gimple (1995)
Circulation 91, 1403-1409
 |  Abstract »  |  Full Text »

Rapid Angiographic Progression of Coronary Artery Disease in Patients With Elevated Lipoprotein(a).

W. Terres, E. Tatsis, B. Pfalzer, F. U. Beil, U. Beisiegel, and C. W. Hamm (1995)
Circulation 91, 948-950
 |  Abstract »  |  Full Text »

Genetic Models of Human Vascular Disease.

V. J. Dzau, G. H. Gibbons, B. K. Kobilka, R. M. Lawn, and R. E. Pratt (1995)
Circulation 91, 521-531
 |  Abstract »  |  Full Text »

Elevated Lipoprotein (a) in Carotid Artery Atherosclerosis is Unrelated to Restenosis After Endarterectomy.

J. Stinson, G. D'Arcy, T. Cooke, M. P. Colgan, M. Hall, J. Tyrrell, K. Gaffney, M. Grouden, D. Moore, D. G. Shanik, et al. (1995)
Vascular and Endovascular Surgery 29, 23-27
 |  Abstract »  |  PDF »

Medical Perspective Antiphospholipid Antibodies, Thrombosis and Atherosclerosis in Systemic Lupus Erythematosus: a Unifying 'Membrane Stress Syndrome' Hypothesis.

P. R.J. Ames (1994)
Lupus 3, 371-377
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Has Lipoprotein 'Little' (a) Shrunk?.

E. S. Barnathan (1993)
JAMA 270, 2224-2225
 |  Abstract »  |  PDF »

Impairment of Collateral Formation in Lipoprotein(a) Transgenic Mice: Therapeutic Angiogenesis Induced by Human Hepatocyte Growth Factor Gene.

R. Morishita, M. Sakaki, K. Yamamoto, S. Iguchi, M. Aoki, K. Yamasaki, K. Matsumoto, T. Nakamura, R. Lawn, T. Ogihara, et al. (2002)
Circulation 105, 1491-1496
 |  Abstract »  |  Full Text »  |  PDF »

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