Science 7 May 1993: Vol. 260. no. 5109, pp. 812 - 816 DOI: 10.1126/science.8484121

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Articles

SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology.

S. M. Woerner, Y. P. Yuan, A. Benner, S. Korff, M. von Knebel Doeberitz, and P. Bork (2009)
Nucleic Acids Res.
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Down-regulation of Epidermal Growth Factor Receptor by Selective Expansion of a 5'-End Regulatory Dinucleotide Repeat in Colon Cancer with Microsatellite Instability.

S. Baranovskaya, Y. Martin, S. Alonso, K. L. Pisarchuk, M. Falchetti, Y. Dai, S. Khaldoyanidi, S. Krajewski, I. Novikova, Y. S. Sidorenko, et al. (2009)
Clin. Cancer Res. 15, 4531-4537
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Implications of Familial Colorectal Cancer Risk Profiles and Microsatellite Instability Status.

S. J. Lubbe, E. L. Webb, I. P. Chandler, and R. S. Houlston (2009)
J. Clin. Oncol. 27, 2238-2244
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CAT25 Is a Mononucleotide Marker to Identify HNPCC Patients.

F. Bianchi, E. Galizia, R. Catalani, L. Belvederesi, C. Ferretti, F. Corradini, and R. Cellerino (2009)
J. Mol. Diagn. 11, 248-252
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An Interstitial Deletion at 3p21.3 Results in the Genetic Fusion of MLH1 and ITGA9 in a Lynch Syndrome Family.

C. Meyer, A. Brieger, G. Plotz, N. Weber, S. Passmann, T. Dingermann, S. Zeuzem, J. Trojan, and R. Marschalek (2009)
Clin. Cancer Res. 15, 762-769
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Human Postmeiotic Segregation 2 Exhibits Biased Repair at Tetranucleotide Microsatellite Sequences.

S. N. Shah and K. A. Eckert (2009)
Cancer Res. 69, 1143-1149
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Established Biomarkers for Colon Cancer.

H.-J. Lenz (2009)
ASCO Educational Book 2009, 215-219
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Hypermutability of Genes in Homo sapiens Due to the Hosting of Long Mono-SSR.

E. Loire, F. Praz, D. Higuet, P. Netter, and G. Achaz (2009)
Mol. Biol. Evol. 26, 111-121
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Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer.

H. Hampel, W. L. Frankel, E. Martin, M. Arnold, K. Khanduja, P. Kuebler, M. Clendenning, K. Sotamaa, T. Prior, J. A. Westman, et al. (2008)
J. Clin. Oncol. 26, 5783-5788
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Microsatellite DNA instability and COPD exacerbations.

D. Makris, N. Tzanakis, A. Damianaki, E. Ntaoukakis, E. Neofytou, M. Zervou, N. M. Siafakas, and E. G. Tzortzaki (2008)
Eur. Respir. J. 32, 612-618
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Immunohistochemistry versus Microsatellite Instability Testing for Screening Colorectal Cancer Patients at Risk for Hereditary Nonpolyposis Colorectal Cancer Syndrome: Part II. The Utility of Microsatellite Instability Testing.

L. Zhang (2008)
J. Mol. Diagn. 10, 301-307
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The Frequency of Muir-Torre Syndrome Among Lynch Syndrome Families.

C. D. South, H. Hampel, I. Comeras, J. A. Westman, W. L. Frankel, and A. de la Chapelle (2008)
J Natl Cancer Inst 100, 277-281
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The genetics of hereditary colon cancer.

A. K. Rustgi (2007)
Genes & Dev. 21, 2525-2538
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Functional Characterization of Pathogenic Human MSH2 Missense Mutations in Saccharomyces cerevisiae.

A. E. Gammie, N. Erdeniz, J. Beaver, B. Devlin, A. Nanji, and M. D. Rose (2007)
Genetics 177, 707-721
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Specific Clinical and Biological Features Characterize Inflammatory Bowel Disease Associated Colorectal Cancers Showing Microsatellite Instability.

M. Svrcek, J. El-Bchiri, A. Chalastanis, E. Capel, S. Dumont, O. Buhard, C. Oliveira, R. Seruca, C. Bossard, J.-F. Mosnier, et al. (2007)
J. Clin. Oncol. 25, 4231-4238
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Mutator pathways unleashed by epigenetic silencing in human cancer.

F. V. Jacinto and M. Esteller (2007)
Mutagenesis 22, 247-253
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Reduced Likelihood of Metastases in Patients with Microsatellite-Unstable Colorectal Cancer.

A. Malesci, L. Laghi, P. Bianchi, G. Delconte, A. Randolph, V. Torri, C. Carnaghi, R. Doci, R. Rosati, M. Montorsi, et al. (2007)
Clin. Cancer Res. 13, 3831-3839
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Cancer genes associated with phenotypes in monoallelic and biallelic mutation carriers: new lessons from old players.

N. Rahman and R. H. Scott (2007)
Hum. Mol. Genet. 16, R60-R66
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Prognostic and Predictive Roles of High-Degree Microsatellite Instability in Colon Cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study.

G. P. Kim, L. H. Colangelo, H. S. Wieand, S. Paik, I. R. Kirsch, N. Wolmark, and C. J. Allegra (2007)
J. Clin. Oncol. 25, 767-772
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Toward a Consensus in Molecular Diagnosis of Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome).

H. T. Lynch, J. F. Lynch, and P. M. Lynch (2007)
J Natl Cancer Inst 99, 261-263
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Wnt pathway may not be implicated in all routes to colorectal cancer * Author's reply.

J R Jass and J Behrens (2007)
Gut 56, 309-310
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APC Mutations and Other Genetic and Epigenetic Changes in Colon Cancer.

W. S. Samowitz, M. L. Slattery, C. Sweeney, J. Herrick, R. K. Wolff, and H. Albertsen (2007)
Mol. Cancer Res. 5, 165-170
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Explaining the Familial Colorectal Cancer Risk Associated with Mismatch Repair (MMR)-Deficient and MMR-Stable Tumors.

L. Aaltonen, L. Johns, H. Jarvinen, J.-P. Mecklin, and R. Houlston (2007)
Clin. Cancer Res. 13, 356-361
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Distal Colorectal Cancers with Microsatellite Instability (MSI) Display Distinct Gene Expression Profiles that Are Different from Proximal MSI Cancers.

T. Watanabe, T. Kobunai, E. Toda, Y. Yamamoto, T. Kanazawa, Y. Kazama, J. Tanaka, T. Tanaka, T. Konishi, Y. Okayama, et al. (2006)
Cancer Res. 66, 9804-9808
 |  Abstract »  |  Full Text »  |  PDF »

ASCO/SSO Review of Current Role of Risk-Reducing Surgery in Common Hereditary Cancer Syndromes.

J. G. Guillem, W. C. Wood, J. F. Moley, A. Berchuck, B. Y. Karlan, D. G. Mutch, R. F. Gagel, J. Weitzel, M. Morrow, B. L. Weber, et al. (2006)
J. Clin. Oncol. 24, 4642-4660
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Simplified detection of microsatellite instability in colorectal cancer without the need for corresponding germline DNA analysis..

M Ebinger, K Sotlar, A Weber, C T Bock, B D Bultmann, and R Kandolf (2006)
J. Clin. Pathol. 59, 1114-1115
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Genetic Dissection of Complex Traits.

E. S. Lander and N. J. Schork (2006)
Focus 4, 442
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Celecoxib treatment alters the gene expression profile of normal colonic mucosa..

O. K. Glebov, L. M. Rodriguez, P. Lynch, S. Patterson, H. Lynch, K. Nakahara, J. Jenkins, J. Cliatt, C.-J. Humbyrd, J. DeNobile, et al. (2006)
Cancer Epidemiol. Biomarkers Prev. 15, 1382-1391
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Comparison of the Microsatellite Instability Analysis System and the Bethesda Panel for the Determination of Microsatellite Instability in Colorectal Cancers.

K. M. Murphy, S. Zhang, T. Geiger, M. J. Hafez, J. Bacher, K. D. Berg, and J. R. Eshleman (2006)
J. Mol. Diagn. 8, 305-311
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Loss of heterozygosity in human aberrant crypt foci (ACF), a putative precursor of colon cancer.

L. Luo, G.-Q. Shen, K. A. Stiffler, Q. K. Wang, T. G. Pretlow, and T. P. Pretlow (2006)
Carcinogenesis 27, 1153-1159
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DNMT3b Polymorphism and Hereditary Nonpolyposis Colorectal Cancer Age of Onset..

J. S. Jones, C. I. Amos, M. Pande, X. Gu, J. Chen, I. M. Campos, Q. Wei, M. Rodriguez-Bigas, P. M. Lynch, and M. L. Frazier (2006)
Cancer Epidemiol. Biomarkers Prev. 15, 886-891
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Detection of microsatellite instability in endometrial cancer: advantages of a panel of five mononucleotide repeats over the National Cancer Institute panel of markers.

Y. F. Wong, T. H. Cheung, K. W. K. Lo, S. F. Yim, L. K. Y. Chan, O. Buhard, A. Duval, T. K. H. Chung, and R. Hamelin (2006)
Carcinogenesis 27, 951-955
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Clinicopathologic Significance of Defective DNA Mismatch Repair in Endometrial Carcinoma.

D. Black, R. A. Soslow, D. A. Levine, C. Tornos, S. C. Chen, A. J. Hummer, F. Bogomolniy, N. Olvera, R. R. Barakat, and J. Boyd (2006)
J. Clin. Oncol. 24, 1745-1753
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Genome-wide differences between microsatellite stable and unstable colorectal tumors.

J. Camps, G. Armengol, J. del Rey, J. J. Lozano, H. Vauhkonen, E. Prat, J. Egozcue, L. Sumoy, S. Knuutila, and R. Miro (2006)
Carcinogenesis 27, 419-428
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Mutually Exclusive Promoter Hypermethylation Patterns of hMLH1 and O6-Methylguanine DNA Methyltransferase in Colorectal Cancer.

E. J. Fox, D. T. Leahy, R. Geraghty, H. E. Mulcahy, D. Fennelly, J. M. Hyland, D. P. O'Donoghue, and K. Sheahan (2006)
J. Mol. Diagn. 8, 68-75
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Multipopulation Analysis of Polymorphisms in Five Mononucleotide Repeats Used to Determine the Microsatellite Instability Status of Human Tumors.

O. Buhard, F. Cattaneo, Y. F. Wong, S. F. Yim, E. Friedman, J.-F. Flejou, A. Duval, and R. Hamelin (2006)
J. Clin. Oncol. 24, 241-251
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The Relationship between Global Methylation Level, Loss of Heterozygosity, and Microsatellite Instability in Sporadic Colorectal Cancer.

K. Matsuzaki, G. Deng, H. Tanaka, S. Kakar, S. Miura, and Y. S. Kim (2005)
Clin. Cancer Res. 11, 8564-8569
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Postreplicative Joining of DNA Double-Strand Breaks Causes Genomic Instability in DNA-PKcs-Deficient Mouse Embryonic Fibroblasts.

M. Martin, A. Genesca, L. Latre, I. Jaco, G. E. Taccioli, J. Egozcue, M. A. Blasco, G. Iliakis, and L. Tusell (2005)
Cancer Res. 65, 10223-10232
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Promoter methylation of the hMLH1 gene and protein expression of human mutL homolog 1 and human mutS homolog 2 in resected esophageal squamous cell carcinoma.

C. Tzao, H.-S. Hsu, G.-H. Sun, H.-L. Lai, Y.-C. Wang, H.-J. Tung, C.-P. Yu, Y.-L. Cheng, and S.-C. Lee (2005)
J. Thorac. Cardiovasc. Surg. 130, 1371
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Use of Molecular Tumor Characteristics to Prioritize Mismatch Repair Gene Testing in Early-Onset Colorectal Cancer.

M. C. Southey, M. A. Jenkins, L. Mead, J. Whitty, M. Trivett, A. A. Tesoriero, L. D. Smith, K. Jennings, G. Grubb, S. G. Royce, et al. (2005)
J. Clin. Oncol. 23, 6524-6532
 |  Abstract »  |  Full Text »  |  PDF »

Determination of TP53 Mutation Is More Relevant Than Microsatellite Instability Status for the Prediction of Disease-Free Survival in Adjuvant-Treated Stage III Colon Cancer Patients.

J. L. Westra, M. Schaapveld, H. Hollema, J. P. de Boer, M. M.J. Kraak, D. de Jong, A. ter Elst, N. H. Mulder, C. H.C.M. Buys, R. M.W. Hofstra, et al. (2005)
J. Clin. Oncol. 23, 5635-5643
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Differential nonsense mediated decay of mutated mRNAs in mismatch repair deficient colorectal cancers.

J. El-Bchiri, O. Buhard, V. Penard-Lacronique, G. Thomas, R. Hamelin, and A. Duval (2005)
Hum. Mol. Genet. 14, 2435-2442
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Mutations in Two Short Noncoding Mononucleotide Repeats in Most Microsatellite-Unstable Colorectal Cancers.

T. Hienonen, H. Sammalkorpi, S. Enholm, P. Alhopuro, T. D. Barber, R. Lehtonen, N. N. Nupponen, H. Lehtonen, R. Salovaara, J.-P. Mecklin, et al. (2005)
Cancer Res. 65, 4607-4613
 |  Abstract »  |  Full Text »  |  PDF »

A Rare Transporter Associated with Antigen Processing Polymorphism Overpresented in HLAlow Colon Cancer Reveals the Functional Significance of the Signature Domain in Antigen Processing.

T. Yang, P. E. Lapinski, H. Zhao, Q. Zhou, H. Zhang, M. Raghavan, Y. Liu, and P. Zheng (2005)
Clin. Cancer Res. 11, 3614-3623
 |  Abstract »  |  Full Text »  |  PDF »

Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer).

H. Hampel, W. L. Frankel, E. Martin, M. Arnold, K. Khanduja, P. Kuebler, H. Nakagawa, K. Sotamaa, T. W. Prior, J. Westman, et al. (2005)
N. Engl. J. Med. 352, 1851-1860
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Association between family history and mismatch repair in colorectal cancer.

R P Coggins, L Cawkwell, S M Bell, G P Crockford, P Quirke, P J Finan, and D T Bishop (2005)
Gut 54, 636-642
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Repeated Sequences in CASPASE-5 and FANCD2 but not NF1 Are Targets for Mutation in Microsatellite-Unstable Acute Leukemia/Myelodysplastic Syndrome.

J. Offman, K. Gascoigne, F. Bristow, P. Macpherson, M. Bignami, I. Casorelli, G. Leone, L. Pagano, S. Sica, O. Halil, et al. (2005)
Mol. Cancer Res. 3, 251-260
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Melanocytic dysplastic naevi occupy the middle ground between benign melanocytic naevi and cutaneous malignant melanomas: emerging clues.

M R Hussein (2005)
J. Clin. Pathol. 58, 453-456
 |  Abstract »  |  Full Text »  |  PDF »

Progress in Genetic Testing, Classification, and Identification of Lynch Syndrome.

H. F. A. Vasen and C. R. Boland (2005)
JAMA 293, 2028-2030
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A Lack of DNA Mismatch Repair on an Athymic Murine Background Predisposes to Hematologic Malignancy.

M. R. Campbell, P. N. Nation, and S. E. Andrew (2005)
Cancer Res. 65, 2626-2635
 |  Abstract »  |  Full Text »  |  PDF »

No MSH6 germline mutations in breast cancer families with colorectal and/or endometrial cancer.

P Vahteristo, S Ojala, A Tamminen, J Tommiska, H Sammalkorpi, S Kiuru-Kuhlefelt, H Eerola, L A Aaltonen, K Aittomaki, and H Nevanlinna (2005)
J. Med. Genet. 42, e22
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Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability.

S. Oda, Y. Maehara, Y. Ikeda, E. Oki, A. Egashira, Y. Okamura, I. Takahashi, Y. Kakeji, Y. Sumiyoshi, K. Miyashita, et al. (2005)
Nucleic Acids Res. 33, 1628-1636
 |  Abstract »  |  Full Text »  |  PDF »

Mismatch Repair System and Aging: Microsatellite Instability in Peripheral Blood Cells From Differently Aged Participants.

S. Neri, A. Gardini, A. Facchini, F. Olivieri, C. Franceschi, G. Ravaglia, and E. Mariani (2005)
J. Gerontol. A Biol. Sci. Med. Sci. 60, 285-292
 |  Abstract »  |  Full Text »  |  PDF »

Mutants with Temperature-Sensitive Defects in the Escherichia coli Mismatch Repair System: Sensitivity to Mispairs Generated In Vivo.

E. S. Hong, A. Yeung, P. Funchain, M. M. Slupska, and J. H. Miller (2005)
J. Bacteriol. 187, 840-846
 |  Abstract »  |  Full Text »  |  PDF »

Diet, Lifestyle, and Genomic Instability in the North Carolina Colon Cancer Study.

J. A. Satia, T. Keku, J. A. Galanko, C. Martin, R. T. Doctolero, A. Tajima, R. S. Sandler, and J. M. Carethers (2005)
Cancer Epidemiol. Biomarkers Prev. 14, 429-436
 |  Abstract »  |  Full Text »  |  PDF »

Low levels of microsatellite instability characterize MLH1 and MSH2 HNPCC carriers before tumor diagnosis.

H. Alazzouzi, E. Domingo, S. Gonzalez, I. Blanco, M. Armengol, E. Espin, A. Plaja, S. Schwartz, G. Capella, and S. Schwartz Jr (2005)
Hum. Mol. Genet. 14, 235-239
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Hereditary Cancer Predisposition Syndromes.

J. E. Garber and K. Offit (2005)
J. Clin. Oncol. 23, 276-292
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The changing face of familial colorectal cancer.

A. Banerjea, S. Clark, and S. Dorudi (2005)
BMJ 330, 2-3
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Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma.

C M Wright, O F Dent, R C Newland, M Barker, P H Chapuis, E L Bokey, J P Young, B A Leggett, J R Jass, and G A Macdonald (2005)
Gut 54, 103-108
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Lower Incidence of Colorectal Cancer and Later Age of Disease Onset in 27 Families With Pathogenic MSH6 Germline Mutations Compared With Families With MLH1 or MSH2 Mutations: The German Hereditary Nonpolyposis Colorectal Cancer Consortium.

J. Plaschke, C. Engel, S. Kruger, E. Holinski-Feder, C. Pagenstecher, E. Mangold, G. Moeslein, K. Schulmann, J. Gebert, M. von Knebel Doeberitz, et al. (2004)
J. Clin. Oncol. 22, 4486-4494
 |  Abstract »  |  Full Text »  |  PDF »

Microsatellite Instability and MLH1 Promoter Methylation in Human Retinoblastoma.

K. W. Choy, C. P. Pang, D. S. P. Fan, T. C. Lee, J. H. Wang, D. H. Abramson, K. W. Lo, K. F. To, C. B. O. Yu, K. L. Beaverson, et al. (2004)
Invest. Ophthalmol. Vis. Sci. 45, 3404-3409
 |  Abstract »  |  Full Text »  |  PDF »

Pancreatic Insulinomas in Multiple Endocrine Neoplasia, Type I Knockout Mice Can Develop in the Absence of Chromosome Instability or Microsatellite Instability.

P. C. Scacheri, A. L. Kennedy, K. Chin, M. T. Miller, J. G. Hodgson, J. W. Gray, S. J. Marx, A. M. Spiegel, and F. S. Collins (2004)
Cancer Res. 64, 7039-7044
 |  Abstract »  |  Full Text »  |  PDF »

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.

C. Oliveira, J. L. Westra, D. Arango, M. Ollikainen, E. Domingo, A. Ferreira, S. Velho, R. Niessen, K. Lagerstedt, P. Alhopuro, et al. (2004)
Hum. Mol. Genet. 13, 2303-2311
 |  Abstract »  |  Full Text »  |  PDF »

DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma.

M. R. Velangi, E. C. Matheson, G. J. Morgan, G. H. Jackson, P. R. Taylor, A. G. Hall, and J. A.E. Irving (2004)
Carcinogenesis 25, 1795-1803
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of microsatellite instability in children treated for acute lymphocytic leukemia with elevated HPRT mutant frequencies.

H. E. Kendall, P. M. Vacek, and B. A. Finette (2004)
Mutagenesis 19, 409-412
 |  Abstract »  |  Full Text »  |  PDF »

BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing.

E Domingo, P Laiho, M Ollikainen, M Pinto, L Wang, A J French, J Westra, T Frebourg, E Espin, M Armengol, et al. (2004)
J. Med. Genet. 41, 664-668
 |  Abstract »  |  Full Text »  |  PDF »

Defective DNA mismatch repair in acute myeloid leukemia/myelodysplastic syndrome after organ transplantation.

J. Offman, G. Opelz, B. Doehler, D. Cummins, O. Halil, N. R. Banner, M. M. Burke, D. Sullivan, P. Macpherson, and P. Karran (2004)
Blood 104, 822-828
 |  Abstract »  |  Full Text »  |  PDF »

Microsatellite instability as indicator of MSH2 gene mutation in patients with upper urinary tract transitional cell carcinoma.

M Roupret, J Catto, F Coulet, A-R Azzouzi, N Amira, T Karmouni, G Fromont, M Sibony, G Vallancien, B Gattegno, et al. (2004)
J. Med. Genet. 41, e91
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Colorectal cancer without high microsatellite instability and chromosomal instability--an alternative genetic pathway to human colorectal cancer.

R. Tang, C. R. Changchien, M.-C. Wu, C.-W. Fan, K.-W. Liu, J.-S. Chen, H.-T. Chien, and L.-L. Hsieh (2004)
Carcinogenesis 25, 841-846
 |  Abstract »  |  Full Text »  |  PDF »

The mutator pathway is a feature of immunodeficiency-related lymphomas.

A. Duval, M. Raphael, C. Brennetot, H. Poirel, O. Buhard, A. Aubry, A. Martin, A. Krimi, V. Leblond, J. Gabarre, et al. (2004)
PNAS 101, 5002-5007
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Pathogenic Human MSH2 Missense Mutations Using Yeast as a Model System: A Laboratory Course in Molecular Biology.

A. E. Gammie and N. Erdeniz (2004)
CBE Life Sci Educ 3, 31-48
 |  Abstract »  |  Full Text »  |  PDF »

A founder MLH1 mutation in families from the districts of Modena and Reggio-Emilia in northern Italy with hereditary non-polyposis colorectal cancer associated with protein elongation and instability.

O Caluseriu, C Di Gregorio, E Lucci-Cordisco, M Santarosa, J Trojan, A Brieger, P Benatti, M Pedroni, T Colibazzi, A Bellacosa, et al. (2004)
J. Med. Genet. 41, e34-34
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A Founder Mutation of the MSH2 Gene and Hereditary Nonpolyposis Colorectal Cancer in the United States.

H. T. Lynch, S. M. Coronel, R. Okimoto, H. Hampel, K. Sweet, J. F. Lynch, A. Barrows, J. Wijnen, H. van der Klift, P. Franken, et al. (2004)
JAMA 291, 718-724
 |  Abstract »  |  Full Text »  |  PDF »

A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability.

Y. Ionov, S.-I. Matsui, and J. K. Cowell (2004)
PNAS 101, 1273-1278
 |  Abstract »  |  Full Text »  |  PDF »

Loss of MSH3 Protein Expression Is Frequent in MLH1-Deficient Colorectal Cancer and Is Associated with Disease Progression1.

J. Plaschke, S. Kruger, B. Jeske, F. Theissig, F. R. Kreuz, S. Pistorius, H. D. Saeger, I. Iaccarino, G. Marra, and H. K. Schackert (2004)
Cancer Res. 64, 864-870
 |  Abstract »  |  Full Text »  |  PDF »

The Oxidized Deoxynucleoside Triphosphate Pool Is a Significant Contributor to Genetic Instability in Mismatch Repair-Deficient Cells.

M. T. Russo, M. F. Blasi, F. Chiera, P. Fortini, P. Degan, P. Macpherson, M. Furuichi, Y. Nakabeppu, P. Karran, G. Aquilina, et al. (2004)
Mol. Cell. Biol. 24, 465-474
 |  Abstract »  |  Full Text »  |  PDF »

Aetiology of colorectal cancer and relevance of monogenic inheritance.

M Ponz de Leon, P Benatti, F Borghi, M Pedroni, A Scarselli, C Di Gregorio, L Losi, A Viel, M Genuardi, G Abbati, et al. (2004)
Gut 53, 115-122
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Toward New Strategies to Select Young Endometrial Cancer Patients for Mismatch Repair Gene Mutation Analysis.

M. J.W. Berends, Y. Wu, R. H. Sijmons, T. van der Sluis, W. B. Ek, M. J.L. Ligtenberg, N. J.W. Arts, K. A. ten Hoor, J. H. Kleibeuker, E. G.E. de Vries, et al. (2003)
J. Clin. Oncol. 21, 4364-4370
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Deletion in a (T)8 microsatellite abrogates expression regulation by 3'-UTR.

T. Ruggiero, M. Olivero, A. Follenzi, L. Naldini, R. Calogero, and M. F. Di Renzo (2003)
Nucleic Acids Res. 31, 6561-6569
 |  Abstract »  |  Full Text »  |  PDF »

Unfavorable Prognostic Factors Associated with High Frequency of Microsatellite Instability and Comparative Genomic Hybridization Analysis in Endometrial Cancer.

A. Hirasawa, D. Aoki, J. Inoue, I. Imoto, N. Susumu, K. Sugano, S. Nozawa, and J. Inazawa (2003)
Clin. Cancer Res. 9, 5675-5682
 |  Abstract »  |  Full Text »  |  PDF »

Dietary Factors and Microsatellite Instability in Sporadic Colon Carcinomas.

B. Diergaarde, H. Braam, G. N. P. van Muijen, M. J. L. Ligtenberg, F. J. Kok, and E. Kampman (2003)
Cancer Epidemiol. Biomarkers Prev. 12, 1130-1136
 |  Abstract »  |  Full Text »  |  PDF »

Artificial Intelligence in Predicting Bladder Cancer Outcome: A Comparison of Neuro-Fuzzy Modeling and Artificial Neural Networks.

J. W. F. Catto, D. A. Linkens, M. F. Abbod, M. Chen, J. L. Burton, K. M. Feeley, and F. C. Hamdy (2003)
Clin. Cancer Res. 9, 4172-4177
 |  Abstract »  |  Full Text »  |  PDF »

Automated, Multiplex Assay for High-Frequency Microsatellite Instability in Colorectal Cancer.

G.M. Nash, M. Gimbel, J. Shia, A.T. Culliford, D.R. Nathanson, M. Ndubuisi, Y. Yamaguchi, Z.S. Zeng, F. Barany, and P.B. Paty (2003)
J. Clin. Oncol. 21, 3105-3112
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Genomic rearrangements of hMSH6 contribute to the genetic predisposition in suspected hereditary non-polyposis colorectal cancer syndrome.

J Plaschke, J Ruschoff, and H K Schackert (2003)
J. Med. Genet. 40, 597-600
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Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer.

C. M. Ribic, D. J. Sargent, M. J. Moore, S. N. Thibodeau, A. J. French, R. M. Goldberg, S. R. Hamilton, P. Laurent-Puig, R. Gryfe, L. E. Shepherd, et al. (2003)
N. Engl. J. Med. 349, 247-257
 |  Abstract »  |  Full Text »  |  PDF »

A Specific Genetic Alteration on Chromosome 6 in Ulcerative Colitis-associated Colorectal Cancers.

T. Ezaki, M. Watanabe, N. Inoue, T. Kanai, H. Ogata, Y. Iwao, H. Ishii, and T. Hibi (2003)
Cancer Res. 63, 3747-3749
 |  Abstract »  |  Full Text »  |  PDF »

Mutations of the Birt-Hogg-Dube (BHD) gene in sporadic colorectal carcinomas and colorectal carcinoma cell lines with microsatellite instability.

J-H Shin, Y-K Shin, J-L Ku, S-Y Jeong, S-H Hong, S-Y Park, W-H Kim, and J-G Park (2003)
J. Med. Genet. 40, 364-367
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Genetic testing for polyposis: practical and ethical aspects.

H J Jarvinen (2003)
Gut 52, ii19-22
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Amplification of repeat-containing transcribed sequences (ARTS): a transcriptome fingerprinting strategy to detect functionally relevant microsatellite mutations in cancer.

M. Olivero, T. Ruggiero, N. Coltella, A. Maffe', R. Calogero, E. Medico, and M. F. Di Renzo (2003)
Nucleic Acids Res. 31, e33
 |  Abstract »  |  Full Text »  |  PDF »

Incidence of Microsatellite Instability in Synchronous Tumors of the Ovary and Endometrium.

C. Shannon, J. Kirk, R. Barnetson, J. Evans, M. Schnitzler, M. Quinn, N. Hacker, A. Crandon, and P. Harnett (2003)
Clin. Cancer Res. 9, 1387-1392
 |  Abstract »  |  Full Text »  |  PDF »

Hereditary Colorectal Cancer.

H. T. Lynch and A. de la Chapelle (2003)
N. Engl. J. Med. 348, 919-932
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Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin.

H. Shimodaira, A. Yoshioka-Yamashita, R. D. Kolodner, and J. Y. J. Wang (2003)
PNAS 100, 2420-2425
 |  Abstract »  |  Full Text »  |  PDF »

Cigarette smoking and genetic alterations in sporadic colon carcinomas.

B. Diergaarde, A. Vrieling, A. A. van Kraats, G. N.P. van Muijen, F. J. Kok, and E. Kampman (2003)
Carcinogenesis 24, 565-571
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Tumor Markers With Prognostic Impact in Dukes' Stages B and C Colorectal Cancer Patients.

C. B. Diep, L. Thorstensen, G. I. Meling, E. Skovlund, T. O. Rognum, and R. A. Lothe (2003)
J. Clin. Oncol. 21, 820-829
 |  Abstract »  |  Full Text »  |  PDF »

High Incidence of Microsatellite Instability in Colorectal Cancer from African Americans.

H. Ashktorab, D. T. Smoot, J. M. Carethers, M. Rahmanian, R. Kittles, G. Vosganian, M. Doura, E. Nidhiry, T. Naab, B. Momen, et al. (2003)
Clin. Cancer Res. 9, 1112-1117
 |  Abstract »  |  Full Text »  |  PDF »

Msh2 deficiency enhances somatic Apc and p53 mutations in Apc+/-Msh2-/- mice.

K.-J. Sohn, M. Choi, J. Song, S. Chan, A. Medline, S. Gallinger, and Y.-I. Kim (2003)
Carcinogenesis 24, 217-224
 |  Abstract »  |  Full Text »  |  PDF »

A novel case with germline p53 gene mutation having concurrent multiple primary colon tumours.

M Miyaki, T Iijima, M Ohue, Y Kita, T Hishima, T Kuroki, T Iwama, and T Mori (2003)
Gut 52, 304-306
 |  Abstract »  |  Full Text »  |  PDF »

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