Science 26 March 1993: Vol. 259. no. 5103, pp. 1918 - 1921 DOI: 10.1126/science.8456318

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Articles

Novel Mechanisms of Fibroblast Growth Factor Receptor 1 Regulation by Extracellular Matrix Protein Anosmin-1.

Y. Hu, S. E. Guimond, P. Travers, S. Cadman, E. Hohenester, J. E. Turnbull, S.-H. Kim, and P.-M. Bouloux (2009)
J. Biol. Chem. 284, 29905-29920
 |  Abstract »  |  Full Text »  |  PDF »

ATP-binding on Fibroblast Growth Factor 2 Partially Overlaps with the Heparin-binding Domain.

K. Rose, S. Pallast, S. Klumpp, and J. Krieglstein (2008)
J. Biochem. 144, 343-347
 |  Abstract »  |  Full Text »  |  PDF »

Evidence That Heparin Saccharides Promote FGF2 Mitogenesis through Two Distinct Mechanisms.

S. J. Goodger, C. J. Robinson, K. J. Murphy, N. Gasiunas, N. J. Harmer, T. L. Blundell, D. A. Pye, and J. T. Gallagher (2008)
J. Biol. Chem. 283, 13001-13008
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Non-canonical fibroblast growth factor signalling in angiogenesis.

M. Murakami, A. Elfenbein, and M. Simons (2008)
Cardiovasc Res 78, 223-231
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Cellular Signaling by Fibroblast Growth Factors (FGFs) and Their Receptors (FGFRs) in Male Reproduction.

L. M. Cotton, M. K. O'Bryan, and B. T. Hinton (2008)
Endocr. Rev. 29, 193-216
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Fibroblast Growth Factor Receptor 1 (FGFR1) Tyrosine Phosphorylation Regulates Binding of FGFR Substrate 2{alpha} (FRS2{alpha}) But Not FRS2 to the Receptor.

Y. Zhang, K. McKeehan, Y. Lin, J. Zhang, and F. Wang (2008)
Mol. Endocrinol. 22, 167-175
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A Molecular Mechanism for the Heparan Sulfate Dependence of Slit-Robo Signaling.

S.-A. Hussain, M. Piper, N. Fukuhara, L. Strochlic, G. Cho, J. A. Howitt, Y. Ahmed, A. K. Powell, J. E. Turnbull, C. E. Holt, et al. (2006)
J. Biol. Chem. 281, 39693-39698
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Antiangiogenic Antithrombin Blocks the Heparan Sulfate-dependent Binding of Proangiogenic Growth Factors to Their Endothelial Cell Receptors: EVIDENCE FOR DIFFERENTIAL BINDING OF ANTIANGIOGENIC AND ANTICOAGULANT FORMS OF ANTITHROMBIN TO PROANGIOGENIC HEPARAN SULFATE DOMAINS.

W. Zhang, R. Swanson, Y. Xiong, B. Richard, and S. T. Olson (2006)
J. Biol. Chem. 281, 37302-37310
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Control of Fibroblast Growth Factor (FGF) 7- and FGF1-induced Mitogenesis and Downstream Signaling by Distinct Heparin Octasaccharide Motifs.

Y. Luo, S. Ye, M. Kan, and W. L. McKeehan (2006)
J. Biol. Chem. 281, 21052-21061
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Inhibition or Activation of Apert Syndrome FGFR2 (S252W) Signaling by Specific Glycosaminoglycans.

L. M. McDowell, B. A. Frazier, D. R. Studelska, K. Giljum, J. Chen, J. Liu, K. Yu, D. M. Ornitz, and L. Zhang (2006)
J. Biol. Chem. 281, 6924-6930
 |  Abstract »  |  Full Text »  |  PDF »

Novel heparanase-inhibiting antibody reduces neointima formation..

H. A. Myler, E. A. Lipke, E. E. Rice, and J. L. West (2006)
J. Biochem. 139, 339-345
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Cooperative Dimerization of Fibroblast Growth Factor 1 (FGF1) upon a Single Heparin Saccharide May Drive the Formation of 2:2:1 FGF1{middle dot}FGFR2c{middle dot}Heparin Ternary Complexes.

C. J. Robinson, N. J. Harmer, S. J. Goodger, T. L. Blundell, and J. T. Gallagher (2005)
J. Biol. Chem. 280, 42274-42282
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Heparin Octasaccharides Inhibit Angiogenesis In vivo.

J. Hasan, S. D. Shnyder, A. R. Clamp, A. T. McGown, R. Bicknell, M. Presta, M. Bibby, J. Double, S. Craig, D. Leeming, et al. (2005)
Clin. Cancer Res. 11, 8172-8179
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Fibroblast Growth Factor-2 Activity by Human Ovarian Cancer Tumor Endothelium.

M. K. Whitworth, A. C. Backen, A. R. Clamp, G. Wilson, R. McVey, A. Friedl, A. C. Rapraeger, G. David, A. McGown, R. J. Slade, et al. (2005)
Clin. Cancer Res. 11, 4282-4288
 |  Abstract »  |  Full Text »  |  PDF »

Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity.

N. Nagai, H. Habuchi, J. D. Esko, and K. Kimata (2004)
J. Cell Sci. 117, 3331-3341
 |  Abstract »  |  Full Text »  |  PDF »

Distinctive Expression Patterns of Heparan Sulfate O-Sulfotransferases and Regional Differences in Heparan Sulfate Structure in Chick Limb Buds.

K. Nogami, H. Suzuki, H. Habuchi, N. Ishiguro, H. Iwata, and K. Kimata (2004)
J. Biol. Chem. 279, 8219-8229
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Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly.

B. L. Allen and A. C. Rapraeger (2003)
J. Cell Biol. 163, 637-648
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Modulation of Mitogenic Activity of Fibroblast Growth Factors by Inorganic Polyphosphate.

T. Shiba, D. Nishimura, Y. Kawazoe, Y. Onodera, K. Tsutsumi, R. Nakamura, and M. Ohshiro (2003)
J. Biol. Chem. 278, 26788-26792
 |  Abstract »  |  Full Text »  |  PDF »

Enhancement of Neurite Outgrowth-Promoting Activity by Heparin Derivatives in Sodium Chlorate-Treated Explant Cultures of Rat Central Neurons.

S. Usuki, Y. Kariya, H. Rosner, M. Ishihara, T. Sakamoto, H. Masuda, and M. Kyogashima (2003)
J. Biochem. 133, 783-790
 |  Abstract »  |  Full Text »  |  PDF »

The Involvement of Heparan Sulfate (HS) in FGF1/HS/FGFR1 Signaling Complex.

Z. L. Wu, L. Zhang, T. Yabe, B. Kuberan, D. L. Beeler, A. Love, and R. D. Rosenberg (2003)
J. Biol. Chem. 278, 17121-17129
 |  Abstract »  |  Full Text »  |  PDF »

Biological Effects of Heparan Sulfates and Regioselectively Modified Heparin-Heparan Mimetics.

H. Baumann (2003)
Journal of Bioactive and Compatible Polymers 18, 59-81
 |  Abstract »  |  PDF »

Dermatan Sulfate Binds and Potentiates Activity of Keratinocyte Growth Factor (FGF-7).

J. M. Trowbridge, J. A. Rudisill, D. Ron, and R. L. Gallo (2002)
J. Biol. Chem. 277, 42815-42820
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Fibroblast Growth Factor Receptors 1 and 2 Interact Differently with Heparin/Heparan Sulfate. IMPLICATIONS FOR DYNAMIC ASSEMBLY OF A TERNARY SIGNALING COMPLEX.

A. K. Powell, D. G. Fernig, and J. E. Turnbull (2002)
J. Biol. Chem. 277, 28554-28563
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Heparin Amplifies Platelet-derived Growth Factor (PDGF)- BB-induced PDGF alpha -Receptor but Not PDGF beta -Receptor Tyrosine Phosphorylation in Heparan Sulfate-deficient Cells. EFFECTS ON SIGNAL TRANSDUCTION AND BIOLOGICAL RESPONSES.

C. Rolny, D. Spillmann, U. Lindahl, and L. Claesson-Welsh (2002)
J. Biol. Chem. 277, 19315-19321
 |  Abstract »  |  Full Text »  |  PDF »

Not All Perlecans Are Created Equal. INTERACTIONS WITH FIBROBLAST GROWTH FACTOR (FGF) 2 AND FGF RECEPTORS.

S. Knox, C. Merry, S. Stringer, J. Melrose, and J. Whitelock (2002)
J. Biol. Chem. 277, 14657-14665
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Increased responsiveness of hypoxic endothelial cells to FGF2 is mediated by HIF-1{alpha}-dependent regulation of enzymes involved in synthesis of heparan sulfate FGF2-binding sites.

J. Li, N. W. Shworak, and M. Simons (2002)
J. Cell Sci. 115, 1951-1959
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Heparan Sulfate Proteoglycans as Regulators of Fibroblast Growth Factor-2 Receptor Binding in Breast Carcinomas.

C. Mundhenke, K. Meyer, S. Drew, and A. Friedl (2002)
Am. J. Pathol. 160, 185-194
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Inhibition of vascular smooth muscle cell proliferation by a novel fibroblast growth factor receptor antagonist.

A. Segev, D. Aviezer, M. Safran, Z. Gross, and A. Yayon (2002)
Cardiovasc Res 53, 232-241
 |  Abstract »  |  Full Text »  |  PDF »

A Rare Premalignant Prostate Tumor Epithelial Cell Syndecan-1 Forms a Fibroblast Growth Factor-binding Complex with Progression-promoting Ectopic Fibroblast Growth Factor Receptor 1.

X. Wu, M. Kan, F. Wang, C. Jin, C. Yu, and W. L. McKeehan (2001)
Cancer Res. 61, 5295-5302
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Development of a High Throughput Screening Assay for Inhibitors of Fibroblast Growth Factor-Receptor-Heparin Interactions.

D. Aviezer, A. P. Seddon, M. J. Wildey, P. Bohlen, and A. Yayon (2001)
J Biomol Screen 6, 171-177
 |  Abstract »  |  PDF »

Regulation of FGF-1 mitogenic activity by heparan sulfate oligosaccharides is dependent on specific structural features: differential requirements for the modulation of FGF-1 and FGF-2.

D. A. Pye, R. R. Vives, P. Hyde, and J. T. Gallagher (2000)
Glycobiology 10, 1183-1192
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Porphyrin Analogues as Novel Antagonists of Fibroblast Growth Factor and Vascular Endothelial Growth Factor Receptor Binding That Inhibit Endothelial Cell Proliferation, Tumor Progression, and Metastasis.

D. Aviezer, S. Cotton, M. David, A. Segev, N. Khaselev, N. Galili, Z. Gross, and A. Yayon (2000)
Cancer Res. 60, 2973-2980
 |  Abstract »  |  Full Text »  |  PDF »

Syndecan-2 Is Involved in the Mitogenic Activity and Signaling of Granulocyte-Macrophage Colony-stimulating Factor in Osteoblasts.

D. Modrowski, M. Basle, A. Lomri, and P. J. Marie (2000)
J. Biol. Chem. 275, 9178-9185
 |  Abstract »  |  Full Text »  |  PDF »

The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the Targeted N-Sulfoglucosamine.

H. Habuchi, M. Tanaka, O. Habuchi, K. Yoshida, H. Suzuki, K. Ban, and K. Kimata (2000)
J. Biol. Chem. 275, 2859-2868
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Differential ability of heparan sulfate proteoglycans to assemble the fibroblast growth factor receptor complex in situ.

Z. CHANG, K. MEYER, A. C. RAPRAEGER, and A. FRIEDL (2000)
FASEB J 14, 137-144
 |  Abstract »  |  Full Text »

Similarities and Differences between the Effects of Heparin and Glypican-1 on the Bioactivity of Acidic Fibroblast Growth Factor and the Keratinocyte Growth Factor.

B. Berman, O. Ostrovsky, M. Shlissel, T. Lang, D. Regan, I. Vlodavsky, R. Ishai-Michaeli, and D. Ron (1999)
J. Biol. Chem. 274, 36132-36138
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Mapping Ligand Binding Domains in Chimeric Fibroblast Growth Factor Receptor Molecules. MULTIPLE REGIONS DETERMINE LIGAND BINDING SPECIFICITY.

A. Chellaiah, W. Yuan, M. Chellaiah, and D. M. Ornitz (1999)
J. Biol. Chem. 274, 34785-34794
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Acidic pH Modulates the Interaction between Human Granulocyte-Macrophage Colony-stimulating Factor and Glycosaminoglycans.

A. Wettreich, A. Sebollela, M. A. Carvalho, S. P. Azevedo, R. Borojevic, S. T. Ferreira, and T. Coelho-Sampaio (1999)
J. Biol. Chem. 274, 31468-31475
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Requirement for Anticoagulant Heparan Sulfate in the Fibroblast Growth Factor Receptor Complex.

W. L. McKeehan, X. Wu, and M. Kan (1999)
J. Biol. Chem. 274, 21511-21514
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Highly Sensitive Sequencing of the Sulfated Domains of Heparan Sulfate.

C. L. R. Merry, M. Lyon, J. A. Deakin, J. J. Hopwood, and J. T. Gallagher (1999)
J. Biol. Chem. 274, 18455-18462
 |  Abstract »  |  Full Text »  |  PDF »

Specificity for Fibroblast Growth Factors Determined by Heparan Sulfate in a Binary Complex with the Receptor Kinase.

M. Kan, X. Wu, F. Wang, and W. L. McKeehan (1999)
J. Biol. Chem. 274, 15947-15952
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Monomer Complexes of Basic Fibroblast Growth Factor and Heparan Sulfate Oligosaccharides Are the Minimal Functional Unit for Cell Activation.

D. A. Pye and J. T. Gallagher (1999)
J. Biol. Chem. 274, 13456-13461
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Basic Fibroblast Growth Factor Binding and Activity by Cell Density and Heparan Sulfate.

T. P. Richardson, V. Trinkaus-Randall, and M. A. Nugent (1999)
J. Biol. Chem. 274, 13534-13540
 |  Abstract »  |  Full Text »  |  PDF »

Fibroblast Growth Factor-10. A SECOND CANDIDATE STROMAL TO EPITHELIAL CELL ANDROMEDIN IN PROSTATE.

W. Lu, Y. Luo, M. Kan, and W. L. McKeehan (1999)
J. Biol. Chem. 274, 12827-12834
 |  Abstract »  |  Full Text »  |  PDF »

Molecular characteristics of fibroblast growth factor-fibroblast growth factor receptor-heparin-like glycosaminoglycan complex.

G. Venkataraman, R. Raman, V. Sasisekharan, and R. Sasisekharan (1999)
PNAS 96, 3658-3663
 |  Abstract »  |  Full Text »  |  PDF »

Functional Analysis of Conserved Cysteines in Heparan Sulfate N-Deacetylase-N-sulfotransferases.

Z. Wei and S. J. Swiedler (1999)
J. Biol. Chem. 274, 1966-1970
 |  Abstract »  |  Full Text »  |  PDF »

Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development.

X Lin, E. Buff, N Perrimon, and A. Michelson (1999)
Development 126, 3715-3723
 |  Abstract »  |  PDF »

Heparan Sulfate Oligosaccharides Require 6-O-Sulfation for Promotion of Basic Fibroblast Growth Factor Mitogenic Activity.

D. A. Pye, R. R. Vives, J. E. Turnbull, P. Hyde, and J. T. Gallagher (1998)
J. Biol. Chem. 273, 22936-22942
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Syndecan-4 Phosphorylation in Vivo.

A. Horowitz and M. Simons (1998)
J. Biol. Chem. 273, 10914-10918
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Characterization and Expression of Heparan-sulfate 6-Sulfotransferase. COMPLETE cDNA CLONING IN HUMAN AND PARTIAL CLONING IN CHINESE HAMSTER OVARY CELLS.

H. Habuchi, M. Kobayashi, and K. Kimata (1998)
J. Biol. Chem. 273, 9208-9213
 |  Abstract »  |  Full Text »  |  PDF »

Structural Modification of Fibroblast Growth Factor-binding Heparan Sulfate at a Determinative Stage of Neural Development.

Y. G. Brickman, M. D. Ford, J. T. Gallagher, V. Nurcombe, P. F. Bartlett, and J. E. Turnbull (1998)
J. Biol. Chem. 273, 4350-4359
 |  Abstract »  |  Full Text »  |  PDF »

Deleted in Colorectal Carcinoma (DCC) Binds Heparin via Its Fifth Fibronectin Type III Domain.

K. L. Bennett, J. Bradshaw, T. Youngman, J. Rodgers, B. Greenfield, A. Aruffo, and P. S. Linsley (1997)
J. Biol. Chem. 272, 26940-26946
 |  Abstract »  |  Full Text »  |  PDF »

A Homeo-interaction Sequence in the Ectodomain of the Fibroblast Growth Factor Receptor.

F. Wang, M. Kan, K. McKeehan, J.-H. Jang, S. Feng, and W. L. McKeehan (1997)
J. Biol. Chem. 272, 23887-23895
 |  Abstract »  |  Full Text »  |  PDF »

In Vitro Assessment of the Biological Activity of Basic Fibroblast Growth Factor Released from Various Polymers and Biomatrices.

M. J. Davies, C. A. Mitchell, M. A. L. Maley, M. D. Grounds, A. R. Harvey, G. W. Plant, D. J. Wood, Y. Hong, and T. V. Chirila (1997)
J Biomater Appl 12, 31-56
 |  Abstract »  |  PDF »

Heparin-induced Self-association of Fibroblast Growth Factor-2. EVIDENCE FOR TWO OLIGOMERIZATION PROCESSES.

A. B. Herr, D. M. Ornitz, R. Sasisekharan, G. Venkataraman, and G. Waksman (1997)
J. Biol. Chem. 272, 16382-16389
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Characterization of the Heparin Binding Properties of Annexin II Tetramer.

G. Kassam, A. Manro, C. E. Braat, P. Louie, S. L. Fitzpatrick, and D. M. Waisman (1997)
J. Biol. Chem. 272, 15093-15100
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Cloning and Expression of Chinese Hamster Ovary Cell Heparan-sulfate 2-Sulfotransferase.

M. Kobayashi, H. Habuchi, M. Yoneda, O. Habuchi, and K. Kimata (1997)
J. Biol. Chem. 272, 13980-13985
 |  Abstract »  |  Full Text »  |  PDF »

The Interaction between Basic Fibroblast Growth Factor and Heparan Sulfate Can Prevent the in Vitro Degradation of the Glycosaminoglycan by Chinese Hamster Ovary Cell Heparanases.

S. Tumova and K. J. Bame (1997)
J. Biol. Chem. 272, 9078-9085
 |  Abstract »  |  Full Text »  |  PDF »

Heparin Binding and Oligomerization of Hepatocyte Growth Factor/Scatter Factor Isoforms. HEPARAN SULFATE GLYCOSAMINOGLYCAN REQUIREMENT FOR Met BINDING AND SIGNALING.

H. Sakata, S. J. Stahl, W. G. Taylor, J. M. Rosenberg, K. Sakaguchi, P. T. Wingfield, and J. S. Rubin (1997)
J. Biol. Chem. 272, 9457-9463
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of a Fibroblast Growth Factor (FGF) Binding Domain in the Cysteine-rich FGF Receptor.

Z. Zhou, M. E. Zuber, L. W. Burrus, and B. B. Olwin (1997)
J. Biol. Chem. 272, 5167-5174
 |  Abstract »  |  Full Text »  |  PDF »

Biological Roles of Fibroblast Growth Factor-2.

A. Bikfalvi, S. Klein, G. Pintucci, and D. B. Rifkin (1997)
Endocr. Rev. 18, 26-45
 |  Abstract »  |  Full Text »

Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila.

T. Haerry, T. Heslip, J. Marsh, and M. O'Connor (1997)
Development 124, 3055-3064
 |  Abstract »  |  PDF »

Essential role of heparan sulfates in axon navigation and targeting in the developing visual system.

A Walz, S McFarlane, Y. Brickman, V Nurcombe, P. Bartlett, and C. Holt (1997)
Development 124, 2421-2430
 |  Abstract »  |  PDF »

Embryoglycans regulate FGF-2-mediated mesoderm induction in the rabbit embryo.

P Dvorak, J. Flechon, E. Thompson, V Horak, P Adenot, and J. Renard (1997)
J. Cell Sci. 110, 1-10
 |  Abstract »  |  PDF »

Sequence of the Hexameric Juvenile Hormone-binding Protein from the Hemolymph of Locusta migratoria.

R. P. Braun and G. R. Wyatt (1996)
J. Biol. Chem. 271, 31756-31762
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Modeling and Deletion Mutagenesis Implicate the Nuclear Translocation Sequence in Structural Integrity of Fibroblast Growth Factor-1.

Y. Luo, J. L. Gabriel, F. Wang, X. Zhan, T. Maciag, M. Kan, and W. L. McKeehan (1996)
J. Biol. Chem. 271, 26876-26883
 |  Abstract »  |  Full Text »  |  PDF »

Divalent Cations and Heparin/Heparan Sulfate Cooperate to Control Assembly and Activity of the Fibroblast Growth Factor Receptor Complex.

M. Kan, F. Wang, M. Kan, B. To, J. L. Gabriel, and W. L. McKeehan (1996)
J. Biol. Chem. 271, 26143-26148
 |  Abstract »  |  Full Text »  |  PDF »

Basic Fibroblast Growth Factor Binds Its Receptors, Is Internalized, and Stimulates DNA Synthesis in Balb/c3T3 Cells in the Absence of Heparan Sulfate.

M. Fannon and M. A. Nugent (1996)
J. Biol. Chem. 271, 17949-17956
 |  Abstract »  |  Full Text »  |  PDF »

The Nuclear Trafficking of Extracellular Fibroblast Growth Factor (FGF)-1 Correlates with the Perinuclear Association of the FGF Receptor-1alpha Isoforms but Not the FGF Receptor-1beta Isoforms.

I. A. Prudovsky, N. Savion, T. M. LaVallee, and T. Maciag (1996)
J. Biol. Chem. 271, 14198-14205
 |  Abstract »  |  Full Text »  |  PDF »

Copper and Calcium Binding Motifs in the Extracellular Domains of Fibroblast Growth Factor Receptors.

G. Patstone and P. Maher (1996)
J. Biol. Chem. 271, 3343-3346
 |  Abstract »  |  Full Text »  |  PDF »

Chimeric Molecules between Keratinocyte Growth Factor and Basic Fibroblast Growth Factor Define Domains That Confer Receptor Binding Specificities.

R. Reich-Slotky, E. Shaoul, B. Berman, G. Graziani, and D. Ron (1995)
J. Biol. Chem. 270, 29813-29818
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Heparan Sulfate Oligosaccharides That Bind to Hepatocyte Growth Factor.

S. Ashikari, H. Habuchi, and K. Kimata (1995)
J. Biol. Chem. 270, 29586-29593
 |  Abstract »  |  Full Text »  |  PDF »

Seeding With Omental Cells Prevents Late Neointimal Hyperplasia in Small-Diameter Dacron Grafts.

M. Pasic, W. Muller-Glauser, B. Odermatt, M. Lachat, B. Seifert, and M. Turina (1995)
Circulation 92, 2605-2616
 |  Abstract »  |  Full Text »

Heparan Sulfates Mediate the Binding of Basic Fibroblast Growth Factor to a Specific Receptor on Neural Precursor Cells.

Y. G. Brickman, M. D. Ford, D. H. Small, P. F. Bartlett, and V. Nurcombe (1995)
J. Biol. Chem. 270, 24941-24948
 |  Abstract »  |  Full Text »  |  PDF »

Fibroblast Growth Factor-2 Can Mediate Cell Attachment by Linking Receptors and Heparan Sulfate Proteoglycans on Neighboring Cells.

C. Richard, J. P. Liuzzo, and D. Moscatelli (1995)
J. Biol. Chem. 270, 24188-24196
 |  Abstract »  |  Full Text »  |  PDF »

Platelet Factor-4 Inhibits the Mitogenic Activity of VEGF[IMAGE] and VEGF[IMAGE] Using Several Concurrent Mechanisms.

S. Gengrinovitch, S. M. Greenberg, T. Cohen, H. Gitay-Goren, P. Rockwell, T. E. Maione, B.-Z. Levi, and G. Neufeld (1995)
J. Biol. Chem. 270, 15059-15065
 |  Abstract »  |  Full Text »  |  PDF »

Ligand-specific Structural Domains in the Fibroblast Growth Factor Receptor.

F. Wang, M. Kan, J. Xu, G. Yan, and W. L. McKeehan (1995)
J. Biol. Chem. 270, 10222-10230
 |  Abstract »  |  Full Text »  |  PDF »

Alternately Spliced NH[IMAGE]-terminal Immunoglobulin-like Loop I in the Ectodomain of the Fibroblast Growth Factor (FGF) Receptor 1 Lowers Affinity for both Heparin and FGF-1.

F. Wang, M. Kan, G. Yan, J. Xu, and W. L. McKeehan (1995)
J. Biol. Chem. 270, 10231-10235
 |  Abstract »  |  Full Text »  |  PDF »

FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides.

D. Ornitz, A. Herr, M Nilsson, J Westman, C. Svahn, and G Waksman (1995)
Science 268, 432-436
 |  Abstract »  |  PDF »

Characterisation of a laminarin sulphate which inhibits basic fibroblast growth factor binding and endothelial cell proliferation.

R Hoffman, D. Paper, J Donaldson, S Alban, and G Franz (1995)
J. Cell Sci. 108, 3591-3598
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Function of the syndecans--a family of cell surface proteoglycans.

K Elenius and M Jalkanen (1994)
J. Cell Sci. 107, 2975-2982
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The expression of basic fibroblast growth factor and its receptor in cell lines derived from normal human mammary gland and a benign mammary lesion.

Y Ke, D. Fernig, M. Wilkinson, J. Winstanley, J. Smith, P. Rudland, and R Barraclough (1993)
J. Cell Sci. 106, 135-143
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Heparan sulfate proteoglycan and FGF receptor target basic FGF to different intracellular destinations.

J Reiland and A. Rapraeger (1993)
J. Cell Sci. 105, 1085-1093
 |  Abstract »  |  PDF »

The Proliferative and Migratory Activities of Breast Cancer Cells Can Be Differentially Regulated by Heparan Sulfates.

V. Nurcombe, C. E. Smart, H. Chipperfield, S. M. Cool, B. Boilly, and H. Hondermarck (2000)
J. Biol. Chem. 275, 30009-30018
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Alternatively Spliced Fibroblast Growth Factor Receptor 3 Isoform Lacking the Acid Box Domain Is Expressed during Chondrogenic Differentiation of ATDC5 Cells.

A. Shimizu, K. Tada, C. Shukunami, Y. Hiraki, T. Kurokawa, N. Magane, and M. Kurokawa-Seo (2001)
J. Biol. Chem. 276, 11031-11040
 |  Abstract »  |  Full Text »  |  PDF »

Preparation of Completely 6-O-Desulfated Heparin and Its Ability to Enhance Activity of Basic Fibroblast Growth Factor.

Y. Kariya, M. Kyogashima, K. Suzuki, T. Isomura, T. Sakamoto, K. Horie, M. Ishihara, R. Takano, K. Kamei, and S. Hara (2000)
J. Biol. Chem. 275, 25949-25958
 |  Abstract »  |  Full Text »  |  PDF »

Crystal Structure of Fibroblast Growth Factor 9 Reveals Regions Implicated in Dimerization and Autoinhibition.

A. N. Plotnikov, A. V. Eliseenkova, O. A. Ibrahimi, Z. Shriver, R. Sasisekharan, M. A. Lemmon, and M. Mohammadi (2001)
J. Biol. Chem. 276, 4322-4329
 |  Abstract »  |  Full Text »  |  PDF »

Probing Fibroblast Growth Factor Dimerization and Role of Heparin-like Glycosaminoglycans in Modulating Dimerization and Signaling.

C.-P. Kwan, G. Venkataraman, Z. Shriver, R. Raman, D. Liu, Y. Qi, L. Varticovski, and R. Sasisekharan (2001)
J. Biol. Chem. 276, 23421-23429
 |  Abstract »  |  Full Text »  |  PDF »

Binding of Heparin/Heparan Sulfate to Fibroblast Growth Factor Receptor 4.

B.-M. Loo, J. Kreuger, M. Jalkanen, U. Lindahl, and M. Salmivirta (2001)
J. Biol. Chem. 276, 16868-16876
 |  Abstract »  |  Full Text »  |  PDF »

Drosophila Heparan Sulfate 6-O-Sulfotransferase (dHS6ST) Gene. STRUCTURE, EXPRESSION, AND FUNCTION IN THE FORMATION OF THE TRACHEAL SYSTEM.

K. Kamimura, M. Fujise, F. Villa, S. Izumi, H. Habuchi, K. Kimata, and H. Nakato (2001)
J. Biol. Chem. 276, 17014-17021
 |  Abstract »  |  Full Text »  |  PDF »

Dissociation of Heparan Sulfate and Receptor Binding Domains of Hepatocyte Growth Factor Reveals That Heparan Sulfate-c-Met Interaction Facilitates Signaling.

J. S. Rubin, R. M. Day, D. Breckenridge, N. Atabey, W. G. Taylor, S. J. Stahl, P. T. Wingfield, J. D. Kaufman, R. Schwall, and D. P. Bottaro (2001)
J. Biol. Chem. 276, 32977-32983
 |  Abstract »  |  Full Text »  |  PDF »

Selectively Desulfated Heparin Inhibits Fibroblast Growth Factor-induced Mitogenicity and Angiogenesis.

L. Lundin, H. Larsson, J. Kreuger, S. Kanda, U. Lindahl, M. Salmivirta, and L. Claesson-Welsh (2000)
J. Biol. Chem. 275, 24653-24660
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Type I Fibroblast Growth Factor Receptor Activates Mitogenic Signaling in the Absence of Detectable Tyrosine Phosphorylation of FRS2.

M. E. Lopez and M. Korc (2000)
J. Biol. Chem. 275, 15933-15939
 |  Abstract »  |  Full Text »  |  PDF »

Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition.

B. L. Allen, M. S. Filla, and A. C. Rapraeger (2001)
J. Cell Biol. 155, 845-858
 |  Abstract »  |  Full Text »  |  PDF »

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