Science 12 February 1993: Vol. 259. no. 5097, pp. 974 - 977 DOI: 10.1126/science.8094901

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Articles

House Dust Mite Sublingual Immunotherapy: The Role for Transforming Growth Factor-{beta} and Functional Regulatory T Cells.

R. E. O'Hehir, L. M. Gardner, M. P. de Leon, B. J. Hales, M. Biondo, J. A. Douglass, J. M. Rolland, and A. Sandrini (2009)
Am. J. Respir. Crit. Care Med. 180, 936-947
 |  Abstract »  |  Full Text »  |  PDF »

CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice.

C. H. Miao, B. R. Harmeling, S. F. Ziegler, B. C. Yen, T. Torgerson, L. Chen, R. J. Yau, B. Peng, A. R. Thompson, H. D. Ochs, et al. (2009)
Blood 114, 4034-4044
 |  Abstract »  |  Full Text »  |  PDF »

Infectious tolerance via the consumption of essential amino acids and mTOR signaling.

S. P. Cobbold, E. Adams, C. A. Farquhar, K. F. Nolan, D. Howie, K. O. Lui, P. J. Fairchild, A. L. Mellor, D. Ron, and H. Waldmann (2009)
PNAS 106, 12055-12060
 |  Abstract »  |  Full Text »  |  PDF »

Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression.

J. D. Campbell, K. F. Buckland, S. J. McMillan, J. Kearley, W. L.G. Oldfield, L. J. Stern, H. Gronlund, M. van Hage, C. J. Reynolds, R. J. Boyton, et al. (2009)
J. Exp. Med. 206, 1535-1547
 |  Abstract »  |  Full Text »  |  PDF »

Lactobacillus reuteri-induced Regulatory T cells Protect against an Allergic Airway Response in Mice.

K. Karimi, M. D. Inman, J. Bienenstock, and P. Forsythe (2009)
Am. J. Respir. Crit. Care Med. 179, 186-193
 |  Abstract »  |  Full Text »  |  PDF »

Graft rejection as a Th1-type process amenable to regulation by donor Th2-type cells through an interleukin-4/STAT6 pathway.

J. Mariotti, J. Foley, K. Ryan, N. Buxhoeveden, V. Kapoor, S. Amarnath, and D. H. Fowler (2008)
Blood 112, 4765-4775
 |  Abstract »  |  Full Text »  |  PDF »

In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure.

F. Meiler, J. Zumkehr, S. Klunker, B. Ruckert, C. A. Akdis, and M. Akdis (2008)
J. Exp. Med. 205, 2887-2898
 |  Abstract »  |  Full Text »  |  PDF »

Transplantation Survival Is Maintained by Granzyme B+ Regulatory Cells and Adaptive Regulatory T Cells.

D. C. Gondek, V. DeVries, E. C. Nowak, L.-F. Lu, K. A. Bennett, Z. A. Scott, and R. J. Noelle (2008)
J. Immunol. 181, 4752-4760
 |  Abstract »  |  Full Text »  |  PDF »

Pretransplant Infusion of Mesenchymal Stem Cells Prolongs the Survival of a Semiallogeneic Heart Transplant through the Generation of Regulatory T Cells.

F. Casiraghi, N. Azzollini, P. Cassis, B. Imberti, M. Morigi, D. Cugini, R. A. Cavinato, M. Todeschini, S. Solini, A. Sonzogni, et al. (2008)
J. Immunol. 181, 3933-3946
 |  Abstract »  |  Full Text »  |  PDF »

CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-{beta}-dependent manner.

J. Andersson, D. Q. Tran, M. Pesu, T. S. Davidson, H. Ramsey, J. J. O'Shea, and E. M. Shevach (2008)
J. Exp. Med. 205, 1975-1981
 |  Abstract »  |  Full Text »  |  PDF »

Resolving the Conundrum of Islet Transplantation by Linking Metabolic Dysregulation, Inflammation, and Immune Regulation.

X. Huang, D. J. Moore, R. J. Ketchum, C. S. Nunemaker, B. Kovatchev, A. L. McCall, and K. L. Brayman (2008)
Endocr. Rev. 29, 603-630
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms Underlying Blockade of Allograft Acceptance by TLR Ligands.

P. M. Porrett, X. Yuan, D. F. LaRosa, P. T. Walsh, J. Yang, W. Gao, P. Li, J. Zhang, J. M. Ansari, W. W. Hancock, et al. (2008)
J. Immunol. 181, 1692-1699
 |  Abstract »  |  Full Text »  |  PDF »

Long-Term Control of Alloreactive B Cell Responses by the Suppression of T Cell Help.

Y. Li, L. Ma, D. Yin, J. Shen, and A. S. Chong (2008)
J. Immunol. 180, 6077-6084
 |  Abstract »  |  Full Text »  |  PDF »

Mouse Sertoli Cells Display Phenotypical and Functional Traits of Antigen-Presenting Cells in Response to Interferon Gamma.

V. Dal Secco, A. Riccioli, F. Padula, E. Ziparo, and A. Filippini (2008)
Biol Reprod 78, 234-242
 |  Abstract »  |  Full Text »  |  PDF »

The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation.

V. H. Nguyen, S. Shashidhar, D. S. Chang, L. Ho, N. Kambham, M. Bachmann, J. M. Brown, and R. S. Negrin (2008)
Blood 111, 945-953
 |  Abstract »  |  Full Text »  |  PDF »

Bystander Central Memory but Not Effector Memory CD8+ T Cells Suppress Allograft Rejection.

N. Wan, H. Dai, T. Wang, Y. Moore, X. X. Zheng, and Z. Dai (2008)
J. Immunol. 180, 113-121
 |  Abstract »  |  Full Text »  |  PDF »

Ultra-Localization of Foxp3+ T Cells within Renal Allografts Shows Infiltration of Tubules Mimicking Rejection.

K. Brown, V. Moxham, J. Karegli, R. Phillips, S. H. Sacks, and W. Wong (2007)
Am. J. Pathol. 171, 1915-1922
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Regulatory T Cells and Dominant Tolerance by Dendritic Cells Incapable of Full Activation.

S. F. Yates, A. M. Paterson, K. F. Nolan, S. P. Cobbold, N. J. Saunders, H. Waldmann, and P. J. Fairchild (2007)
J. Immunol. 179, 967-976
 |  Abstract »  |  Full Text »  |  PDF »

FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease.

B. Li, A. Samanta, X. Song, K. T. Iacono, P. Brennan, T. A. Chatila, G. Roncador, A. H. Banham, J. L. Riley, Q. Wang, et al. (2007)
Int. Immunol. 19, 825-835
 |  Abstract »  |  Full Text »  |  PDF »

CD8 Blockade Promotes Antigen Responsiveness to Nontolerizing Antigen in Tolerant Mice by Inhibiting Apoptosis of CD4+ T Cells.

Z. Wang and J. D. Davies (2007)
J. Immunol. 178, 6148-6157
 |  Abstract »  |  Full Text »  |  PDF »

Abrogation of Antibody-Mediated Allograft Rejection by Regulatory CD4 T Cells with Indirect Allospecificity.

C. J. Callaghan, F. J. Rouhani, M. C. Negus, A. J. Curry, E. M. Bolton, J. A. Bradley, and G. J. Pettigrew (2007)
J. Immunol. 178, 2221-2228
 |  Abstract »  |  Full Text »  |  PDF »

Frequency of Natural Regulatory CD4+CD25+ T Lymphocytes Determines the Outcome of Tolerance across Fully Mismatched MHC Barrier through Linked Recognition of Self and Allogeneic Stimuli.

R. Fucs, J. T. Jesus, P. H. N. Souza Junior, L. Franco, M. Vericimo, M. Bellio, and A. Nobrega (2006)
J. Immunol. 176, 2324-2329
 |  Abstract »  |  Full Text »  |  PDF »

Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient.

S. G. Zheng, L. Meng, J. H. Wang, M. Watanabe, M. L. Barr, D. V. Cramer, J. D. Gray, and D. A. Horwitz (2006)
Int. Immunol. 18, 279-289
 |  Abstract »  |  Full Text »  |  PDF »

Specificity of CD4+CD25+ Regulatory T Cell Function in Alloimmunity.

A. Sanchez-Fueyo, S. Sandner, A. Habicht, C. Mariat, J. Kenny, N. Degauque, X. X. Zheng, T. B. Strom, L. A. Turka, and M. H. Sayegh (2006)
J. Immunol. 176, 329-334
 |  Abstract »  |  Full Text »  |  PDF »

Axotrophin and leukaemia inhibitory factor (LIF) in transplantation tolerance.

S. M Metcalfe (2005)
Phil Trans R Soc B 360, 1687-1694
 |  Abstract »  |  Full Text »  |  PDF »

T cell tolerance induced by therapeutic antibodies.

S. P Cobbold (2005)
Phil Trans R Soc B 360, 1695-1705
 |  Abstract »  |  Full Text »  |  PDF »

Homeostatic T cell proliferation as a barrier to T cell tolerance.

S. P Hickman and L. A Turka (2005)
Phil Trans R Soc B 360, 1713-1721
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation.

S. A. Quezada, K. Bennett, B. R. Blazar, A. Y. Rudensky, S. Sakaguchi, and R. J. Noelle (2005)
J. Immunol. 175, 771-779
 |  Abstract »  |  Full Text »  |  PDF »

Roles of Deletion and Regulation in Creating Mixed Chimerism and Allograft Tolerance Using a Nonlymphoablative Irradiation-Free Protocol.

C. Domenig, A. Sanchez-Fueyo, J. Kurtz, S. P. Alexopoulos, C. Mariat, M. Sykes, T. B. Strom, and X. X. Zheng (2005)
J. Immunol. 175, 51-60
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory T Cells Suppress In Vitro Proliferation of Virus-Specific CD8+ T Cells during Persistent Hepatitis C Virus Infection.

S. M. Rushbrook, S. M. Ward, E. Unitt, S. L. Vowler, M. Lucas, P. Klenerman, and G. J. M. Alexander (2005)
J. Virol. 79, 7852-7859
 |  Abstract »  |  Full Text »  |  PDF »

CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen-specific reactivation in vivo is critical for bystander regulation.

M. Karim, G. Feng, K. J. Wood, and A. R. Bushell (2005)
Blood 105, 4871-4877
 |  Abstract »  |  Full Text »  |  PDF »

Testicular Immune Privilege Promotes Transplantation Tolerance by Altering the Balance between Memory and Regulatory T Cells.

I. W. Nasr, Y. Wang, G. Gao, S. Deng, L. Diggs, D. M. Rothstein, G. Tellides, F. G. Lakkis, and Z. Dai (2005)
J. Immunol. 174, 6161-6168
 |  Abstract »  |  Full Text »  |  PDF »

The Generation of CD25+CD4+ Regulatory T Cells That Prevent Allograft Rejection Does Not Compromise Immunity to a Viral Pathogen.

A. Bushell, E. Jones, A. Gallimore, and K. Wood (2005)
J. Immunol. 174, 3290-3297
 |  Abstract »  |  Full Text »  |  PDF »

Transplantation Tolerance in NF-{kappa}B-Impaired Mice Is Not Due to Regulation but Is Prevented by Transgenic Expression of Bcl-xL.

P. Zhou, S. J. Balin, M. Mashayekhi, K. W. Hwang, D. A. Palucki, and M.-L. Alegre (2005)
J. Immunol. 174, 3447-3453
 |  Abstract »  |  Full Text »  |  PDF »

Immune regulatory activity of CD34+ progenitor cells: evidence for a deletion-based mechanism mediated by TNF-{alpha}.

H. Gur, R. Krauthgamer, E. Bachar-Lustig, H. Katchman, R. Arbel-Goren, A. Berrebi, T. Klein, A. Nagler, A. Tabilio, M. F. Martelli, et al. (2005)
Blood 105, 2585-2593
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory arthritis and dermatitis in thymectomized, CD25+ cell-depleted adult mice.

A. Loughry, S. Fairchild, N. Athanasou, J. Edwards, and F. C. Hall (2005)
Rheumatology 44, 299-308
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Immunological Tolerance/Hyporesponsiveness in Baboons with a Nondepleting CD4 Antibody.

D. Winsor-Hines, C. Merrill, M. O'Mahony, P. E. Rao, S. P. Cobbold, H. Waldmann, D. J. Ringler, and P. D. Ponath (2004)
J. Immunol. 173, 4715-4723
 |  Abstract »  |  Full Text »  |  PDF »

Adoptive Transfer of Paternal Antigen-Hyporesponsive T Cells Induces Maternal Tolerance to the Allogeneic Fetus in Abortion-Prone Matings.

L.-P. Jin, D.-J. Li, J.-P. Zhang, M.-Y. Wang, X.-Y. Zhu, Y. Zhu, Y. Meng, and M.-M. Yuan (2004)
J. Immunol. 173, 3612-3619
 |  Abstract »  |  Full Text »  |  PDF »

Long-Term Islet Graft Survival in NOD Mice by Abrogation of Recurrent Autoimmunity.

Q. Shi, D. Wang, G. A. Hadley, A. W. Bingaman, S. T. Bartlett, and D. L. Farber (2004)
Diabetes 53, 2338-2345
 |  Abstract »  |  Full Text »  |  PDF »

Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells.

E. Nishimura, T. Sakihama, R. Setoguchi, K. Tanaka, and S. Sakaguchi (2004)
Int. Immunol. 16, 1189-1201
 |  Abstract »  |  Full Text »  |  PDF »

Foxp3 Expressing CD4+CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells.

M. Viguier, F. Lemaitre, O. Verola, M.-S. Cho, G. Gorochov, L. Dubertret, H. Bachelez, P. Kourilsky, and L. Ferradini (2004)
J. Immunol. 173, 1444-1453
 |  Abstract »  |  Full Text »  |  PDF »

Exploiting Tolerance Processes in Transplantation.

H. Waldmann and S. Cobbold (2004)
Science 305, 209-212
 |  Abstract »  |  Full Text »  |  PDF »

Antigen-induced regulatory T cells.

S. Vigouroux, E. Yvon, E. Biagi, and M. K. Brenner (2004)
Blood 104, 26-33
 |  Abstract »  |  Full Text »  |  PDF »

Immune Responses in Healthy and Allergic Individuals Are Characterized by a Fine Balance between Allergen-specific T Regulatory 1 and T Helper 2 Cells.

M. Akdis, J. Verhagen, A. Taylor, F. Karamloo, C. Karagiannidis, R. Crameri, S. Thunberg, G. Deniz, R. Valenta, H. Fiebig, et al. (2004)
J. Exp. Med. 199, 1567-1575
 |  Abstract »  |  Full Text »  |  PDF »

In Vitro-expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes.

Q. Tang, K. J. Henriksen, M. Bi, E. B. Finger, G. Szot, J. Ye, E. L. Masteller, H. McDevitt, M. Bonyhadi, and J. A. Bluestone (2004)
J. Exp. Med. 199, 1455-1465
 |  Abstract »  |  Full Text »  |  PDF »

Generation of Anergic and Regulatory T Cells following Prolonged Exposure to a Harmless Antigen.

T.-C. Chen, S. P. Cobbold, P. J. Fairchild, and H. Waldmann (2004)
J. Immunol. 172, 5900-5907
 |  Abstract »  |  Full Text »  |  PDF »

Induction of foxP3+ Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants.

S. P. Cobbold, R. Castejon, E. Adams, D. Zelenika, L. Graca, S. Humm, and H. Waldmann (2004)
J. Immunol. 172, 6003-6010
 |  Abstract »  |  Full Text »  |  PDF »

Transplantation tolerance induced by intranasal administration of HY peptides.

J.-G. Chai, E. James, H. Dewchand, E. Simpson, and D. Scott (2004)
Blood 103, 3951-3959
 |  Abstract »  |  Full Text »  |  PDF »

Natural and Induced CD4+CD25+ Cells Educate CD4+CD25- Cells to Develop Suppressive Activity: The Role of IL-2, TGF-{beta}, and IL-10.

S. G. Zheng, J. H. Wang, J. D. Gray, H. Soucier, and D. A. Horwitz (2004)
J. Immunol. 172, 5213-5221
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{gamma} Regulation in Anti-CD4 Antibody-Induced T Cell Unresponsiveness.

B. Sawitzki, B. Kieselbach, M. Fisser, C. Meisel, K. Vogt, M. Gaestel, M. Lehmann, K. Risch, G. Grutz, and H.-D. Volk (2004)
J. Am. Soc. Nephrol. 15, 695-703
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ and CD8+ Regulatory T Cells Generated Ex Vivo with IL-2 and TGF-{beta} Suppress a Stimulatory Graft-versus-Host Disease with a Lupus-Like Syndrome.

S. G. Zheng, J. H. Wang, M. N. Koss, F. Quismorio Jr., J. D. Gray, and D. A. Horwitz (2004)
J. Immunol. 172, 1531-1539
 |  Abstract »  |  Full Text »  |  PDF »

IL-15 and Cognate Antigen Successfully Expand De Novo-Induced Human Antigen-Specific Regulatory CD4+ T Cells That Require Antigen-Specific Activation for Suppression.

H. J. P. M. Koenen, E. Fasse, and I. Joosten (2003)
J. Immunol. 171, 6431-6441
 |  Abstract »  |  Full Text »  |  PDF »

Infectious Nickel Tolerance: A Reciprocal Interplay of Tolerogenic APCs and T Suppressor Cells That Is Driven by Immunization.

K. Roelofs-Haarhuis, X. Wu, M. Nowak, M. Fang, S. Artik, and E. Gleichmann (2003)
J. Immunol. 171, 2863-2872
 |  Abstract »  |  Full Text »  |  PDF »

Development of Infectious Tolerance After Donor-Specific Transfusion and Rat Heart Transplantation.

M. Kataoka, J. A. Margenthaler, G. Ku, and M. W. Flye (2003)
J. Immunol. 171, 204-211
 |  Abstract »  |  Full Text »  |  PDF »

CD4+CD25+ Regulatory T Cells Do Not Significantly Contribute to Direct Pathway Hyporesponsiveness in Stable Renal Transplant Patients.

D. S. Game, M. P. Hernandez-Fuentes, A. N. Chaudhry, and R. I. Lechler (2003)
J. Am. Soc. Nephrol. 14, 1652-1661
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of CD40-Mediated Signaling Is Sufficient for Inducing Islet But Not Skin Transplantation Tolerance.

N. E. Phillips, T. G. Markees, J. P. Mordes, D. L. Greiner, and A. A. Rossini (2003)
J. Immunol. 170, 3015-3023
 |  Abstract »  |  Full Text »  |  PDF »

Role of Double-Negative Regulatory T Cells in Long-Term Cardiac Xenograft Survival.

W. Chen, M. S. Ford, K. J. Young, M. I. Cybulsky, and L. Zhang (2003)
J. Immunol. 170, 1846-1853
 |  Abstract »  |  Full Text »  |  PDF »

CD4-Dependent Generation of Dominant Transplantation Tolerance Induced by Simultaneous Perturbation of CD154 and LFA-1 Pathways.

M. R. Nicolls, M. Coulombe, J. Beilke, H. C. Gelhaus, and R. G. Gill (2002)
J. Immunol. 169, 4831-4839
 |  Abstract »  |  Full Text »  |  PDF »

Anti-Human CD4 Induces Peripheral Tolerance in a Human CD4+, Murine CD4-, HLA-DR+ Advanced Transgenic Mouse Model.

R. Laub, R. Brecht, M. Dorsch, U. Valey, K. Wenk, and F. Emmrich (2002)
J. Immunol. 169, 2947-2955
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Regulatory T Cells in Tolerated Allografts.

L. Graca, S. P. Cobbold, and H. Waldmann (2002)
J. Exp. Med. 195, 1641-1646
 |  Abstract »  |  Full Text »  |  PDF »

Both CD4+CD25+ and CD4+CD25- Regulatory Cells Mediate Dominant Transplantation Tolerance.

L. Graca, S. Thompson, C.-Y. Lin, E. Adams, S. P. Cobbold, and H. Waldmann (2002)
J. Immunol. 168, 5558-5565
 |  Abstract »  |  Full Text »  |  PDF »

Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell.

P. A. Taylor, T. M. Friedman, R. Korngold, R. J. Noelle, and B. R. Blazar (2002)
Blood 99, 4601-4609
 |  Abstract »  |  Full Text »  |  PDF »

Role for Thymic and Splenic Regulatory CD4+ T Cells Induced by Donor Dendritic Cells in Allograft Tolerance by LF15-0195 Treatment.

E. Chiffoleau, G. Beriou, P. Dutartre, C. Usal, J.-P. Soulillou, and M. C. Cuturi (2002)
J. Immunol. 168, 5058-5069
 |  Abstract »  |  Full Text »  |  PDF »

Memorizing innate instructions requires a sufficiently specific adaptive immune system.

J. A. M. Borghans and R. J. De Boer (2002)
Int. Immunol. 14, 525-532
 |  Abstract »  |  Full Text »  |  PDF »

Tracking the Immunoregulatory Mechanisms Active During Allograft Tolerance.

A. Sanchez-Fueyo, M. Weber, C. Domenig, T. B. Strom, and X. X. Zheng (2002)
J. Immunol. 168, 2274-2281
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory T Cells Overexpress a Subset of Th2 Gene Transcripts.

D. Zelenika, E. Adams, S. Humm, L. Graca, S. Thompson, S. P. Cobbold, and H. Waldmann (2002)
J. Immunol. 168, 1069-1079
 |  Abstract »  |  Full Text »  |  PDF »

CD25+CD4+ Regulatory T Cells Prevent Graft Rejection: CTLA-4- and IL-10-Dependent Immunoregulation of Alloresponses.

C. I. Kingsley, M. Karim, A. R. Bushell, and K. J. Wood (2002)
J. Immunol. 168, 1080-1086
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Subsets and In Vitro Immune Regulation in ""Infectious"" Transplantation Tolerance.

Y. Zhai, X.-D. Shen, M. Lehmann, R. Busuttil, H.-D. Volk, and J. W. Kupiec-Weglinski (2001)
J. Immunol. 167, 4814-4820
 |  Abstract »  |  Full Text »  |  PDF »

Human CD4+CD25+ cells: a naturally occurring population of regulatory T cells.

W. F. Ng, P. J. Duggan, F. Ponchel, G. Matarese, G. Lombardi, A. D. Edwards, J. D. Isaacs, and R. I. Lechler (2001)
Blood 98, 2736-2744
 |  Abstract »  |  Full Text »  |  PDF »

Persistence of Dominant T Cell Clones in Accepted Solid Organ Transplants.

C. Baron, I. McMorrow, D. H Sachs, and C. LeGuern (2001)
J. Immunol. 167, 4154-4160
 |  Abstract »  |  Full Text »  |  PDF »

IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo.

M. Hara, C. I. Kingsley, M. Niimi, S. Read, S. E. Turvey, A. R. Bushell, P. J. Morris, F. Powrie, and K. J. Wood (2001)
J. Immunol. 166, 3789-3796
 |  Abstract »  |  Full Text »  |  PDF »

Use of Two-Dimensional Gel Electrophoresis To Measure Changes in Synovial Fluid Proteins from Patients with Rheumatoid Arthritis Treated with Antibody to CD4.

M. A. Smith, S. K. Bains, J. C. Betts, E. H. S. Choy, and E. D. Zanders (2001)
Clin. Vaccine Immunol. 8, 105-111
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Characterization of Strain Differences in the Ability to Mediate CD40/CD28-Independent Rejection of Skin Allografts.

M. A. Williams, J. Trambley, J. Ha, A. B. Adams, M. M. Durham, P. Rees, S. R. Cowan, T. C. Pearson, and C. P. Larsen (2000)
J. Immunol. 165, 6849-6857
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance.

L. Graca, K. Honey, E. Adams, S. P. Cobbold, and H. Waldmann (2000)
J. Immunol. 165, 4783-4786
 |  Abstract »  |  Full Text »  |  PDF »

Dynamics of T Lymphocyte Responses: Intermediates, Effectors, and Memory Cells.

A. Lanzavecchia and F. Sallusto (2000)
Science 290, 92-97
 |  Abstract »  |  Full Text »

Control of Experimental Inflammatory Bowel Disease by Regulatory T cells.

C. ASSEMAN, S. FOWLER, and F. POWRIE (2000)
Am. J. Respir. Crit. Care Med. 162, S185-189
 |  Abstract »  |  Full Text »  |  PDF »

Nondepleting Anti-CD4 Has an Immediate Action on Diabetogenic Effector Cells, Halting Their Destruction of Pancreatic {beta} Cells.

J. M. Phillips, S. Z. Harach, N. M. Parish, Z. Fehervari, K. Haskins, and A. Cooke (2000)
J. Immunol. 165, 1949-1955
 |  Abstract »  |  Full Text »  |  PDF »

Anti-TCR-Specific DNA Vaccination Demonstrates a Role for a CD8+ T Cell Clone in the Induction of Allograft Tolerance by Donor-Specific Blood Transfusion.

C. Vignes, E. Chiffoleau, P. Douillard, R. Josien, H. Peche, J.-M. Heslan, C. Usal, J.-P. Soulillou, and M. C. Cuturi (2000)
J. Immunol. 165, 96-101
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory Cells Potentiate the Efficacy of IL-4 Gene Transfer by Up-Regulating Th2-Dependent Expression of Protective Molecules in the Infectious Tolerance Pathway in Transplant Recipients.

B. Ke, T. Ritter, H. Kato, Y. Zhai, J. Li, M. Lehmann, R. W. Busuttil, H.-D. Volk, and J. W. Kupiec-Weglinski (2000)
J. Immunol. 164, 5739-5745
 |  Abstract »  |  Full Text »  |  PDF »

Repertoire Requirements of CD4+ T Cells That Prevent Spontaneous Autoimmune Encephalomyelitis.

D. Olivares-Villagomez, A. K. Wensky, Y. Wang, and J. J. Lafaille (2000)
J. Immunol. 164, 5499-5507
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness.

H. J. P. M. Koenen and I. Joosten (2000)
Blood 95, 3153-3161
 |  Abstract »  |  Full Text »  |  PDF »

Adoptive immunotherapy in canine mixed chimeras after nonmyeloablative hematopoietic cell transplantation.

G. E. Georges, R. Storb, J. D. Thompson, C. Yu, T. Gooley, B. Bruno, and R. A. Nash (2000)
Blood 95, 3262-3269
 |  Abstract »  |  Full Text »  |  PDF »

Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4+ T cells.

G. F. Hoyne, I. Le Roux, M. Corsin-Jimenez, K. Tan, J. Dunne, L. M. G. Forsyth, M. J. Dallman, M. J. Owen, D. Ish-Horowicz, and J. R. Lamb (2000)
Int. Immunol. 12, 177-185
 |  Abstract »  |  Full Text »  |  PDF »

Role of Immunoregulatory Donor T Cells in Suppression of Graft-Versus-Host Disease Following Donor Leukocyte Infusion Therapy.

B. D. Johnson, E. E. Becker, J. L. LaBelle, and R. L. Truitt (1999)
J. Immunol. 163, 6479-6487
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Ligand Blockade Induces CD4+ T Cell Tolerance and Linked Suppression.

K. Honey, S. P. Cobbold, and H. Waldmann (1999)
J. Immunol. 163, 4805-4810
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Donor-Type Chimerism and Transplantation Tolerance Across Major Histocompatibility Barriers in Sublethally Irradiated Mice by Sca-1+Lin- Bone Marrow Progenitor Cells: Synergism With Non-Alloreactive (Host x Donor)F1 T Cells.

E. Bachar-Lustig, H. W. Li, H. Gur, R. Krauthgamer, H. Marcus, and Y. Reisner (1999)
Blood 94, 3212-3221
 |  Abstract »  |  Full Text »  |  PDF »

An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation.

C. Asseman, S. Mauze, M. W. Leach, R. L. Coffman, and F. Powrie (1999)
J. Exp. Med. 190, 995-1004
 |  Abstract »  |  Full Text »  |  PDF »

Anergic CD8+ T Cells Can Persist and Function In Vivo.

C. A. Blish, S. R. Dillon, A. G. Farr, and P. J. Fink (1999)
J. Immunol. 163, 155-164
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Costimulatory Blockade: New Therapies for TransplantRejection.

H. GUDMUNDSDOTTIR and L. A. TURKA (1999)
J. Am. Soc. Nephrol. 10, 1356-1365
 |  Abstract »  |  Full Text »

Chronic Modulation of the TCR Repertoire in the Lymphoid Periphery.

C. A. Blish, B. J. Gallay, G. L. Turk, K. M. Kline, W. Wheat, and P. J. Fink (1999)
J. Immunol. 162, 3131-3140
 |  Abstract »  |  Full Text »  |  PDF »

Tolerance to Antigen-Presenting Cell-Depleted Islet Allografts Is CD4 T Cell Dependent.

M. Coulombe, H. Yang, L. A. Wolf, and R. G. Gill (1999)
J. Immunol. 162, 2503-2510
 |  Abstract »  |  Full Text »  |  PDF »

Dose-Dependent Induction of Distinct Anergic Phenotypes: Multiple Levels of T Cell Anergy.

L. S. Taams, W. van Eden, and M. H. M. Wauben (1999)
J. Immunol. 162, 1974-1981
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for Immune Regulation in the Induction of Transplantation Tolerance: A Conditional but Limited Role for IL-4.

A. Bushell, M. Niimi, P. J. Morris, and K. J. Wood (1999)
J. Immunol. 162, 1359-1366
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Immunologic Tolerance for Transplantation.

A. A. ROSSINI, D. L. GREINER, and J. P. MORDES (1999)
Physiol Rev 79, 99-141
 |  Abstract »  |  Full Text »  |  PDF »

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