Science 18 September 1992: Vol. 257. no. 5077, pp. 1689 - 1694 DOI: 10.1126/science.1388288

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Articles

Phosphorylation by Cyclin C/Cyclin-Dependent Kinase 2 following Mitogenic Stimulation of Murine Fibroblasts Inhibits Transcriptional Activity of LSF during G1 Progression.

U. H. Saxena, C. M. H. Powell, J. K. Fecko, R. Cacioppo, H. S. Chou, G. M. Cooper, and U. Hansen (2009)
Mol. Cell. Biol. 29, 2335-2345
 |  Abstract »  |  Full Text »  |  PDF »

NFATc1 Targets Cyclin A in the Regulation of Vascular Smooth Muscle Cell Multiplication during Restenosis.

M. Karpurapu, D. Wang, N. K. Singh, Q. Li, and G. N. Rao (2008)
J. Biol. Chem. 283, 26577-26590
 |  Abstract »  |  Full Text »  |  PDF »

PDK1 Regulates Cell Proliferation and Cell Cycle Progression through Control of Cyclin D1 and p27Kip1 Expression.

K. Nakamura, H. Sakaue, A. Nishizawa, Y. Matsuki, H. Gomi, E. Watanabe, R. Hiramatsua, M. Tamamori-Adachi, S. Kitajima, T. Noda, et al. (2008)
J. Biol. Chem. 283, 17702-17711
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.

A. C. Minella, K. R. Loeb, A. Knecht, M. Welcker, B. J. Varnum-Finney, I. D. Bernstein, J. M. Roberts, and B. E. Clurman (2008)
Genes & Dev. 22, 1677-1689
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+ signals coordinate zygotic polarization and cell cycle progression in the brown alga Fucus serratus.

J. H. F. Bothwell, J. Kisielewska, M. J. Genner, M. R. McAinsh, and C. Brownlee (2008)
Development 135, 2173-2181
 |  Abstract »  |  Full Text »  |  PDF »

Ligand-induced Degradation of the Ethylene Receptor ETR2 through a Proteasome-dependent Pathway in Arabidopsis.

Y.-F. Chen, S. N. Shakeel, J. Bowers, X.-C. Zhao, N. Etheridge, and G. E. Schaller (2007)
J. Biol. Chem. 282, 24752-24758
 |  Abstract »  |  Full Text »  |  PDF »

Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors.

G. De Falco, E. Leucci, D. Lenze, P. P. Piccaluga, P. P. Claudio, A. Onnis, G. Cerino, J. Nyagol, W. Mwanda, C. Bellan, et al. (2007)
Blood 110, 1301-1307
 |  Abstract »  |  Full Text »  |  PDF »

Erlotinib, an Effective Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Induces p27KIP1 Up-Regulation and Nuclear Translocation in Association with Cell Growth Inhibition and G1/S Phase Arrest in Human Non-Small-Cell Lung Cancer Cell Lines.

Y.-H. Ling, T. Li, Z. Yuan, M. Haigentz Jr., T. K. Weber, and R. Perez-Soler (2007)
Mol. Pharmacol. 72, 248-258
 |  Abstract »  |  Full Text »  |  PDF »

Germ Line Gain of Function with SOS1 Mutation in Hereditary Gingival Fibromatosis.

S.-I. Jang, E.-J. Lee, P. S. Hart, M. Ramaswami, D. Pallos, and T. C. Hart (2007)
J. Biol. Chem. 282, 20245-20255
 |  Abstract »  |  Full Text »  |  PDF »

Constitutive Turnover of Cyclin E by Cul3 Maintains Quiescence.

J. D. McEvoy, U. Kossatz, N. Malek, and J. D. Singer (2007)
Mol. Cell. Biol. 27, 3651-3666
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of a Cyclin E Fragment with Ku70 Regulates Bax-Mediated Apoptosis.

S. Mazumder, D. Plesca, M. Kinter, and A. Almasan (2007)
Mol. Cell. Biol. 27, 3511-3520
 |  Abstract »  |  Full Text »  |  PDF »

Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas.

Y. Ma, S. Fiering, C. Black, X. Liu, Z. Yuan, V. A. Memoli, D. J. Robbins, H. A. Bentley, G. J. Tsongalis, E. Demidenko, et al. (2007)
PNAS 104, 4089-4094
 |  Abstract »  |  Full Text »  |  PDF »

Endoreduplication of human smooth muscle cells induced by 2-methoxyestradiol: a role for cyclin-dependent kinase 2.

Y. Gui, H. Yin, J.-Y. He, S.-H. Yang, M. P. Walsh, and X.-L. Zheng (2007)
Am J Physiol Heart Circ Physiol 292, H1313-H1320
 |  Abstract »  |  Full Text »  |  PDF »

Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1.

S. Arai, K. Miyake, R. Voit, S. Nemoto, E. K. Wakeland, I. Grummt, and T. Miyazaki (2007)
PNAS 104, 2289-2294
 |  Abstract »  |  Full Text »  |  PDF »

HuR Contributes to Cyclin E1 Deregulation in MCF-7 Breast Cancer Cells.

X. Guo and R. S. Hartley (2006)
Cancer Res. 66, 7948-7956
 |  Abstract »  |  Full Text »  |  PDF »

A Calmodulin-Binding Site on Cyclin E Mediates Ca2+-Sensitive G1/S Transitions in Vascular Smooth Muscle Cells.

J. Choi, A. Chiang, N. Taulier, R. Gros, A. Pirani, and M. Husain (2006)
Circ. Res. 98, 1273-1281
 |  Abstract »  |  Full Text »  |  PDF »

The ETS Protein MEF Is Regulated by Phosphorylation-Dependent Proteolysis via the Protein-Ubiquitin Ligase SCFSkp2.

Y. Liu, C. V. Hedvat, S. Mao, X.-H. Zhu, J. Yao, H. Nguyen, A. Koff, and S. D. Nimer (2006)
Mol. Cell. Biol. 26, 3114-3123
 |  Abstract »  |  Full Text »  |  PDF »

Discovery and Evaluation of Dual CDK1 and CDK2 Inhibitors..

M. Payton, G. Chung, P. Yakowec, A. Wong, D. Powers, L. Xiong, N. Zhang, J. Leal, T. L. Bush, V. Santora, et al. (2006)
Cancer Res. 66, 4299-4308
 |  Abstract »  |  Full Text »  |  PDF »

Proliferating Human Cells Hypomorphic for Origin Recognition Complex 2 and Pre-replicative Complex Formation Have a Defect in p53 Activation and Cdk2 Kinase Activation.

J. K. Teer, Y. J. Machida, H. Labit, O. Novac, O. Hyrien, K. Marheineke, M. Zannis-Hadjopoulos, and A. Dutta (2006)
J. Biol. Chem. 281, 6253-6260
 |  Abstract »  |  Full Text »  |  PDF »

Proliferating Cell Nuclear Antigen Recruits Cyclin-dependent Kinase Inhibitor Xic1 to DNA and Couples Its Proteolysis to DNA Polymerase Switching.

L.-C. Chuang and P. R. Yew (2005)
J. Biol. Chem. 280, 35299-35309
 |  Abstract »  |  Full Text »  |  PDF »

p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow.

A. Vidal, S. Zacharoulis, W. Guo, D. Shaffer, F. Giancotti, A. H. Bramley, C. de la Hoz, K. K. Jensen, D. Kato, D. D. MacDonald, et al. (2005)
PNAS 102, 6890-6895
 |  Abstract »  |  Full Text »  |  PDF »

The Tumor-specific Hyperactive Forms of Cyclin E Are Resistant to Inhibition by p21 and p27.

H. Wingate, N. Zhang, M. J. McGarhen, I. Bedrosian, J. W. Harper, and K. Keyomarsi (2005)
J. Biol. Chem. 280, 15148-15157
 |  Abstract »  |  Full Text »  |  PDF »

Combined Evaluation of Expressions of Cyclin E and p53 Proteins as Prognostic Factors for Patients with Gastric Cancer.

K. E. Bani-Hani, N. M. Almasri, Y. S. Khader, F. M. Sheyab, and H. N. Karam (2005)
Clin. Cancer Res. 11, 1447-1453
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Cell-Cycle Arrest by all-trans Retinoic Acid in Mouse Embryonic Palatal Mesenchymal (MEPM) Cells.

Z. Yu, J. Lin, Y. Xiao, J. Han, X. Zhang, H. Jia, Y. Tang, and Y. Li (2005)
Toxicol. Sci. 83, 349-354
 |  Abstract »  |  Full Text »  |  PDF »

Lactoferrin Down-Regulates G1 Cyclin-Dependent Kinases during Growth Arrest of Head and Neck Cancer Cells.

Y. Xiao, C. L. Monitto, K. M. Minhas, and D. Sidransky (2004)
Clin. Cancer Res. 10, 8683-8686
 |  Abstract »  |  Full Text »  |  PDF »

Living with or without cyclins and cyclin-dependent kinases.

C. J. Sherr and J. M. Roberts (2004)
Genes & Dev. 18, 2699-2711
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Sp1 by Cyclin-dependent Kinase 2 Modulates the Role of Sp1 in CTP:Phosphocholine Cytidylyltransferase {alpha} Regulation during the S Phase of the Cell Cycle.

C. Banchio, L. M. Schang, and D. E. Vance (2004)
J. Biol. Chem. 279, 40220-40226
 |  Abstract »  |  Full Text »  |  PDF »

Noncatalytic Requirement for Cyclin A-cdk2 in p27 Turnover.

X.-H. Zhu, H. Nguyen, H. D. Halicka, F. Traganos, and A. Koff (2004)
Mol. Cell. Biol. 24, 6058-6066
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of cyclin-dependent kinase activity during mitotic exit and maintenance of genome stability by p21, p27, and p107.

T. Chibazakura, S. G. McGrew, J. A. Cooper, H. Yoshikawa, and J. M. Roberts (2004)
PNAS 101, 4465-4470
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Cyclin-dependent Kinase 2 by Full Length and Low Molecular Weight Forms of Cyclin E in Breast Cancer Cells.

R. M. Harwell, B. B. Mull, D. C. Porter, and K. Keyomarsi (2004)
J. Biol. Chem. 279, 12695-12705
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Cyclin E Renders Cyclin D-CDK4 Dispensable for Inactivation of the Retinoblastoma Tumor Suppressor Protein, Activation of E2F, and G1-S Phase Progression.

S. M. Keenan, N. H. Lents, and J. J. Baldassare (2004)
J. Biol. Chem. 279, 5387-5396
 |  Abstract »  |  Full Text »  |  PDF »

TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed.

S. P. Persengiev, X. Zhu, B. L. Dixit, G. A. Maston, E. L. W. Kittler, and M. R. Green (2003)
PNAS 100, 14887-14891
 |  Abstract »  |  Full Text »  |  PDF »

Xenopus Autosomal Recessive Hypercholesterolemia Protein Couples Lipoprotein Receptors with the AP-2 Complex in Oocytes and Embryos and Is Required for Vitellogenesis.

Y. Zhou, J. Zhang, and M. L. King (2003)
J. Biol. Chem. 278, 44584-44592
 |  Abstract »  |  Full Text »  |  PDF »

Estrogens Down-regulate p27Kip1 in Breast Cancer Cells through Skp2 and through Nuclear Export Mediated by the ERK Pathway.

J. S. Foster, R. I. Fernando, N. Ishida, K. I. Nakayama, and J. Wimalasena (2003)
J. Biol. Chem. 278, 41355-41366
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin D2 Compensates for the Loss of Cyclin D1 in Estrogen-Induced Mouse Uterine Epithelial Cell Proliferation.

B. Chen and J. W. Pollard (2003)
Mol. Endocrinol. 17, 1368-1381
 |  Abstract »  |  Full Text »  |  PDF »

Differential regulation of cell adhesive functions by integrin {alpha} subunit cytoplasmic tails in vivo.

J. Na, M. Marsden, and D. W. DeSimone (2003)
J. Cell Sci. 116, 2333-2343
 |  Abstract »  |  Full Text »  |  PDF »

Differential Control of Cell Cycle, Proliferation, and Survival of Primary T Lymphocytes by Purine and Pyrimidine Nucleotides.

L. Quemeneur, L.-M. Gerland, M. Flacher, M. Ffrench, J.-P. Revillard, and L. Genestier (2003)
J. Immunol. 170, 4986-4995
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Models in Applied Physiology: Invited Review: Effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest.

R. M. Douglas and G. G. Haddad (2003)
J Appl Physiol 94, 2068-2083
 |  Abstract »  |  Full Text »  |  PDF »

NPAT Expression Is Regulated by E2F and Is Essential for Cell Cycle Progression.

G. Gao, A. P. Bracken, K. Burkard, D. Pasini, M. Classon, C. Attwooll, M. Sagara, T. Imai, K. Helin, and J. Zhao (2003)
Mol. Cell. Biol. 23, 2821-2833
 |  Abstract »  |  Full Text »  |  PDF »

Sequestration of p27Kip1 protein by cyclin D1 in typical and blastic variants of mantle cell lymphoma (MCL): implications for pathogenesis.

L. Quintanilla-Martinez, T. Davies-Hill, F. Fend, J. Calzada-Wack, L. Sorbara, E. Campo, E. S. Jaffe, and M. Raffeld (2003)
Blood 101, 3181-3187
 |  Abstract »  |  Full Text »  |  PDF »

Human cytomegalovirus immediate-early over protein 2 (IE2)-mediated activation of cyclin E is cell-cycle-independent and forces S-phase entry in IE2-arrested cells.

L. Wiebusch, J. Asmar, R. Uecker, and C. Hagemeier (2003)
J. Gen. Virol. 84, 51-60
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of the Raf/MEK/ERK Cascade Is Necessary and Sufficient for Activation and Thr-160 Phosphorylation of a Nuclear-targeted CDK2.

N. H. Lents, S. M. Keenan, C. Bellone, and J. J. Baldassare (2002)
J. Biol. Chem. 277, 47469-47475
 |  Abstract »  |  Full Text »  |  PDF »

Characterization and Expression of Mammalian Cyclin B3, a Prepachytene Meiotic Cyclin.

T. B. Nguyen, K. Manova, P. Capodieci, C. Lindon, S. Bottega, X.-Y. Wang, J. Refik-Rogers, J. Pines, D. J. Wolgemuth, and A. Koff (2002)
J. Biol. Chem. 277, 41960-41969
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Bovine Papillomavirus Replicative Helicase E1 by the Ubiquitin-Proteasome Pathway.

M.-H. Malcles, N. Cueille, F. Mechali, O. Coux, and C. Bonne-Andrea (2002)
J. Virol. 76, 11350-11358
 |  Abstract »  |  Full Text »  |  PDF »

The Oncogenic Activity of Cyclin E Is Not Confined to Cdk2 Activation Alone but Relies on Several Other, Distinct Functions of the Protein.

C. Geisen and T. Moroy (2002)
J. Biol. Chem. 277, 39909-39918
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of p58PITSLRE, a G2/M-specific Protein Kinase, with Cyclin D3.

S. Zhang, M. Cai, S. Zhang, S. Xu, S. Chen, X. Chen, C. Chen, and J. Gu (2002)
J. Biol. Chem. 277, 35314-35322
 |  Abstract »  |  Full Text »  |  PDF »

Mdm4 (Mdmx) Regulates p53-Induced Growth Arrest and Neuronal Cell Death during Early Embryonic Mouse Development.

D. Migliorini, E. L. Denchi, D. Danovi, A. Jochemsen, M. Capillo, A. Gobbi, K. Helin, P. G. Pelicci, and J.-C. Marine (2002)
Mol. Cell. Biol. 22, 5527-5538
 |  Abstract »  |  Full Text »  |  PDF »

Down-regulation of Cdc6, a Cell Cycle Regulatory Gene, in Prostate Cancer.

L. D. Robles, A. R. Frost, M. Davila, A. D. Hutson, W. E. Grizzle, and R. Chakrabarti (2002)
J. Biol. Chem. 277, 25431-25438
 |  Abstract »  |  Full Text »  |  PDF »

Schizosaccharomyces pombe pfh1+ Encodes an Essential 5' to 3' DNA Helicase That Is a Member of the PIF1 Subfamily of DNA Helicases.

J.-Q. Zhou, H. Qi, V. P. Schulz, M. K. Mateyak, E. K. Monson, and V. A. Zakian (2002)
Mol. Biol. Cell 13, 2180-2191
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin E Is a Target of WT1 Transcriptional Repression.

D. M. Loeb, D. Korz, M. Katsnelson, E. A. Burwell, A. D. Friedman, and S. Sukumar (2002)
J. Biol. Chem. 277, 19627-19632
 |  Abstract »  |  Full Text »  |  PDF »

Proteolytic Cleavage of Cyclin E Leads to Inactivation of Associated Kinase Activity and Amplification of Apoptosis in Hematopoietic Cells.

S. Mazumder, B. Gong, Q. Chen, J. A. Drazba, J. C. Buchsbaum, and A. Almasan (2002)
Mol. Cell. Biol. 22, 2398-2409
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin A- and Cyclin E-Cdk Complexes Shuttle between the Nucleus and the Cytoplasm.

M. Jackman, Y. Kubota, N. den Elzen, A. Hagting, and J. Pines (2002)
Mol. Biol. Cell 13, 1030-1045
 |  Abstract »  |  Full Text »  |  PDF »

Novel localization and possible functions of cyclin E in early sea urchin development.

B. J. Schnackenberg and W. F. Marzluff (2002)
J. Cell Sci. 115, 113-121
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of a Thymidylate Synthase (TS)-inducible Cell Line: A Model System for Studying Sensitivity to TS- and non-TS-targeted Chemotherapies.

D. B. Longley, P. R. Ferguson, J. Boyer, T. Latif, M. Lynch, P. Maxwell, D. P. Harkin, and P. G. Johnston (2001)
Clin. Cancer Res. 7, 3533-3539
 |  Abstract »  |  Full Text »  |  PDF »

Neither p21WAF1 Nor 14-3-3{sigma} Prevents G2 Progression to Mitotic Catastrophe in Human Colon Carcinoma Cells after DNA Damage, But p21WAF1 Induces Stable G1 Arrest in Resulting Tetraploid Cells.

P. R. Andreassen, F. B. Lacroix, O. D. Lohez, and R. L. Margolis (2001)
Cancer Res. 61, 7660-7668
 |  Abstract »  |  Full Text »  |  PDF »

Cyclooxygenase-independent actions of cyclooxygenase inhibitors.

I. TEGEDER, J. PFEILSCHIFTER, and G. GEISSLINGER (2001)
FASEB J 15, 2057-2072
 |  Abstract »  |  Full Text »  |  PDF »

HMG Box Transcriptional Repressor HBP1 Maintains a Proliferation Barrier in Differentiated Liver Tissue.

H. H. Shih, M. Xiu, S. P. Berasi, E. M. Sampson, A. Leiter, K. E. Paulson, and A. S. Yee (2001)
Mol. Cell. Biol. 21, 5723-5732
 |  Abstract »  |  Full Text »  |  PDF »

Histone H1 Phosphorylation by Cdk2 Selectively Modulates Mouse Mammary Tumor Virus Transcription through Chromatin Remodeling.

R. N. Bhattacharjee, G. C. Banks, K. W. Trotter, H.-L. Lee, and T. K. Archer (2001)
Mol. Cell. Biol. 21, 5417-5425
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Proteins HMGA1 Induces Cell Cycle Deregulation and Apoptosis in Normal Rat Thyroid Cells.

M. Fedele, G. M. Pierantoni, M. T. Berlingieri, S. Battista, G. Baldassarre, N. Munshi, M. Dentice, D. Thanos, M. Santoro, G. Viglietto, et al. (2001)
Cancer Res. 61, 4583-4590
 |  Abstract »  |  Full Text »  |  PDF »

Accumulation of Cyclin E Is Not a Prerequisite for Passage through the Restriction Point.

S. V. Ekholm, P. Zickert, S. I. Reed, and A. Zetterberg (2001)
Mol. Cell. Biol. 21, 3256-3265
 |  Abstract »  |  Full Text »

Up-Regulation of Cyclin-dependent Kinase 4/Cyclin D2 Expression but Down-Regulation of Cyclin-dependent Kinase 2/Cyclin E in Testicular Germ Cell Tumors.

B. A. Schmidt, A. Rose, C. Steinhoff, T. Strohmeyer, M. Hartmann, and R. Ackermann (2001)
Cancer Res. 61, 4214-4221
 |  Abstract »  |  Full Text »

Tetraploid State Induces p53-dependent Arrest of Nontransformed Mammalian Cells in G1.

P. R. Andreassen, O. D. Lohez, F. B. Lacroix, and R. L. Margolis (2001)
Mol. Biol. Cell 12, 1315-1328
 |  Abstract »  |  Full Text »

A Risk-Stratification Model of Non-Small Cell Lung Cancers Using Cyclin E, Ki-67, and ras p21: Different Roles of G1 Cyclins in Cell Proliferation and Prognosis.

H. Dosaka-Akita, F. Hommura, T. Mishina, S. Ogura, M. Shimizu, H. Katoh, and Y. Kawakami (2001)
Cancer Res. 61, 2500-2504
 |  Abstract »  |  Full Text »

Inhibition of Cyclin E-Cyclin-Dependent Kinase 2 Complex Formation and Activity Is Associated with Cell Cycle Arrest and Withdrawal in Oligodendrocyte Progenitor Cells.

C. A. Ghiani and V. Gallo (2001)
J. Neurosci. 21, 1274-1282
 |  Abstract »  |  Full Text »  |  PDF »

Repression of c-myc Is Necessary but Not Sufficient for Terminal Differentiation of B Lymphocytes In Vitro.

K.-I Lin, Y. Lin, and K. Calame (2000)
Mol. Cell. Biol. 20, 8684-8695
 |  Abstract »  |  Full Text »

Identification and Characterization of a 19q12 Amplicon in Esophageal Adenocarcinomas Reveals Cyclin E as the Best Candidate Gene for this Amplicon.

L. Lin, M. S. Prescott, Z. Zhu, P. Singh, S. Y. Chun, R. D. Kuick, S. M. Hanash, M. B. Orringer, T. W. Glover, and D. G. Beer (2000)
Cancer Res. 60, 7021-7027
 |  Abstract »  |  Full Text »

Mutation of Cyclin/cdk Phosphorylation Sites in HsCdc6 Disrupts a Late Step in Initiation of DNA Replication in Human Cells.

U. Herbig, J. W. Griffith, and E. Fanning (2000)
Mol. Biol. Cell 11, 4117-4130
 |  Abstract »  |  Full Text »

Prognostic Significance of Cyclin E Overexpression in Laryngeal Squamous Cell Carcinomas.

Y. Dong, L. Sui, Y. Tai, K. Sugimoto, T. Hirao, and M. Tokuda (2000)
Clin. Cancer Res. 6, 4253-4258
 |  Abstract »  |  Full Text »  |  PDF »

Retinoic Acid Induces Neuronal Differentiation of Embryonal Carcinoma Cells by Reducing Proteasome-dependent Proteolysis of the Cyclin-dependent Inhibitor p27.

G. Baldassarre, A. Boccia, P. Bruni, C. Sandomenico, M. V. Barone, S. Pepe, T. Angrisano, B. Belletti, M. L. Motti, A. Fusco, et al. (2000)
Cell Growth Differ. 11, 517-526
 |  Abstract »  |  Full Text »

Where the cell cycle and histones meet.

M. E. Ewen (2000)
Genes & Dev. 14, 2265-2270
 |  Full Text »

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription.

J. Zhao, B. K. Kennedy, B. D. Lawrence, D. A. Barbie, A. G. Matera, J. A. Fletcher, and E. Harlow (2000)
Genes & Dev. 14, 2283-2297
 |  Abstract »  |  Full Text »

Cell cycle-regulated phosphorylation of p220NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription.

T. Ma, B. A. Van Tine, Y. Wei, M. D. Garrett, D. Nelson, P. D. Adams, J. Wang, J. Qin, L. T. Chow, and J. W. Harper (2000)
Genes & Dev. 14, 2298-2313
 |  Abstract »  |  Full Text »

Loss of p27Kip1 from Cyclin E/Cyclin-dependent Kinase (CDK) 2 but not from Cyclin D1/CDK4 Complexes in Cells Transformed by Polyamine Biosynthetic Enzymes.

K. Ravanko, K. Järvinen, A. Paasinen-Sohns, and E. Hölttä (2000)
Cancer Res. 60, 5244-5253
 |  Abstract »  |  Full Text »

Cks1 Is Required for G1 Cyclin-Cyclin-Dependent Kinase Activity in Budding Yeast.

G. J. Reynard, W. Reynolds, R. Verma, and R. J. Deshaies (2000)
Mol. Cell. Biol. 20, 5858-5864
 |  Abstract »  |  Full Text »

A U-Rich Element in the 5' Untranslated Region Is Necessary for the Translation of p27 mRNA.

S. S. Millard, A. Vidal, M. Markus, and A. Koff (2000)
Mol. Cell. Biol. 20, 5947-5959
 |  Abstract »  |  Full Text »

The Pezcoller Lecture: Cancer Cell Cycles Revisited.

C. J. Sherr (2000)
Cancer Res. 60, 3689-3695
 |  Abstract »  |  Full Text »

Inducible pRb2/p130 Expression and Growth-suppressive Mechanisms: Evidence of a pRb2/p130, p27Kip1, and Cyclin E Negative Feedback Regulatory Loop.

C. M. Howard, P. P. Claudio, Antonio De Luca, P. Stiegler, F. P. Jori, N. M. Safdar, M. Caputi, K. Khalili, and A. Giordano (2000)
Cancer Res. 60, 2737-2744
 |  Abstract »  |  Full Text »

A Screen for Modifiers of Cyclin E Function in Drosophila melanogaster Identifies Cdk2 Mutations, Revealing the Insignificance of Putative Phosphorylation Sites in Cdk2.

M. E. Lane, M. Elend, D. Heidmann, A. Herr, S. Marzodko, A. Herzig, and C. F. Lehner (2000)
Genetics 155, 233-244
 |  Abstract »  |  Full Text »

Initiation of Human DNA Replication in Vitro Using Nuclei from Cells Arrested at an Initiation-competent State.

T. Krude (2000)
J. Biol. Chem. 275, 13699-13707
 |  Abstract »  |  Full Text »  |  PDF »

P21 and Retinoblastoma Protein Control the Absence of DNA Replication in Terminally Differentiated Muscle Cells.

A. Mal, D. Chattopadhyay, M. K. Ghosh, R. Y.C. Poon, T. Hunter, and M. L. Harter (2000)
J. Cell Biol. 149, 281-292
 |  Abstract »  |  Full Text »  |  PDF »

Flavopiridol, a Cyclin-dependent Kinase Inhibitor, Prevents Spindle Inhibitor-induced Endoreduplication in Human Cancer Cells.

M. Motwani, X.-k. Li, and G. K. Schwartz (2000)
Clin. Cancer Res. 6, 924-932
 |  Abstract »  |  Full Text »

Control of extracellular matrix assembly by syndecan-2 proteoglycan.

C. Klass, J. Couchman, and A Woods (2000)
J. Cell Sci. 113, 493-506
 |  Abstract »  |  PDF »

A critical role for Xdazl, a germ plasm-localized RNA, in the differentiation of primordial germ cells in Xenopus.

D. Houston and M. King (2000)
Development 127, 447-456
 |  Abstract »  |  PDF »

Prognostic Significance of Cyclin E Overexpression in Resected Non-Small Cell Lung Cancer.

T. Fukuse, T. Hirata, H. Naiki, S. Hitomi, and H. Wada (2000)
Cancer Res. 60, 242-244
 |  Abstract »  |  Full Text »

Processing of Cyclin E Differs between Normal and Tumor Breast Cells.

R. M. Harwell, D. C. Porter, C. Danes, and K. Keyomarsi (2000)
Cancer Res. 60, 481-489
 |  Abstract »  |  Full Text »

Cyclin E Expression, a Potential Prognostic Marker for Non-Small Cell Lung Cancers.

T. Mishina, H. Dosaka-Akita, F. Hommura, M. Nishi, T. Kojima, S. Ogura, M. Shimizu, H. Katoh, and Y. Kawakami (2000)
Clin. Cancer Res. 6, 11-16
 |  Abstract »  |  Full Text »

HAESA, an Arabidopsis leucine-rich repeat receptor kinase, controls floral organ abscission.

T.-L. Jinn, J. M. Stone, and J. C. Walker (2000)
Genes & Dev. 14, 108-117
 |  Abstract »  |  Full Text »

Cyclin E-p27 Opposition and Regulation of the G1 Phase of the Cell Cycle in the Murine Neocortical PVE: A Quantitative Analysis of mRNA In Situ Hybridization.

I. Delalle, T. Takahashi, R.S. Nowakowski, L.-H. Tsai, and V.S. Caviness Jr (1999)
Cereb Cortex 9, 824-832
 |  Abstract »  |  Full Text »  |  PDF »

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.

J. D. Singer, M. Gurian-West, B. Clurman, and J. M. Roberts (1999)
Genes & Dev. 13, 2375-2387
 |  Abstract »  |  Full Text »

B Cell Antigen Receptor-Mediated Activation of Cyclin-Dependent Retinoblastoma Protein Kinases and Inhibition by Co-Cross-Linking with Fc{gamma} Receptors.

D. Tanguay, S. Pavlovic, M. J. Piatelli, J. Bartek, and T. C. Chiles (1999)
J. Immunol. 163, 3160-3168
 |  Abstract »  |  Full Text »  |  PDF »

Stat Protein Transactivation Domains Recruit p300/CBP through Widely Divergent Sequences.

M. Paulson, S. Pisharody, L. Pan, S. Guadagno, A. L. Mui, and D. E. Levy (1999)
J. Biol. Chem. 274, 25343-25349
 |  Abstract »  |  Full Text »  |  PDF »

c-Myc Overexpression Uncouples DNA Replication from Mitosis.

Q. Li and C. V. Dang (1999)
Mol. Cell. Biol. 19, 5339-5351
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of cyclin E gene expression by the human papillomavirus type 16 E7 oncoprotein.

B. Vogt, K. Zerfaß-Thome, A. Schulze, J. W. Botz, W. Zwerschke, and P. Jansen-Dürr (1999)
J. Gen. Virol. 80, 2103-2113
 |  Abstract »  |  Full Text »

Cell Cycle Arrest and Inhibition of Anoikis by Galectin-3 in Human Breast Epithelial Cells.

H.-R. C. Kim, H.-M. Lin, H. Biliran, and A. Raz (1999)
Cancer Res. 59, 4148-4154
 |  Abstract »  |  Full Text »  |  PDF »

c-Myc Regulates Cyclin D-Cdk4 and -Cdk6 Activity but Affects Cell Cycle Progression at Multiple Independent Points.

M. K. Mateyak, A. J. Obaya, and J. M. Sedivy (1999)
Mol. Cell. Biol. 19, 4672-4683
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G1/S Transition in Mammalian Cells.

H. Kumagai, N. Sato, M. Yamada, D. Mahony, W. Seghezzi, E. Lees, K.-I. Arai, and H. Masai (1999)
Mol. Cell. Biol. 19, 5083-5095
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin D1 Overexpression in Mouse Epidermis Increases Cyclin-dependent Kinase Activity and Cell Proliferation in Vivo but Does Not Affect Skin Tumor Development.

M. L. Rodriguez-Puebla, M. LaCava, and C. J. Conti (1999)
Cell Growth Differ. 10, 467-472
 |  Abstract »  |  Full Text »

CDK inhibitors: positive and negative regulators of G1-phase progression.

C. J. Sherr and J. M. Roberts (1999)
Genes & Dev. 13, 1501-1512
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Down-regulation of p27Kip1 by Two Mechanisms, Ubiquitin-mediated Degradation and Proteolytic Processing.

M. Shirane, Y. Harumiya, N. Ishida, A. Hirai, C. Miyamoto, S. Hatakeyama, K.-i. Nakayama, and M. Kitagawa (1999)
J. Biol. Chem. 274, 13886-13893
 |  Abstract »  |  Full Text »  |  PDF »

Adenovirus-mediated Gene Transfer of MMAC1/PTEN to Glioblastoma Cells Inhibits S Phase Entry by the Recruitment of p27Kip1 into Cyclin E/CDK2 Complexes.

I. W. Cheney, S. T. C. Neuteboom, M.-T. Vaillancourt, M. Ramachandra, and R. Bookstein (1999)
Cancer Res. 59, 2318-2323
 |  Abstract »  |  Full Text »  |  PDF »

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