Science 11 September 1992: Vol. 257. no. 5076, pp. 1496 - 1502 DOI: 10.1126/science.1523409

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Articles

Biochemical Factors Governing the Steady-State Estrone/Estradiol Ratios Catalyzed by Human 17{beta}-Hydroxysteroid Dehydrogenases Types 1 and 2 in HEK-293 Cells.

D. P. Sherbet, O. L. Guryev, M. Papari-Zareei, D. Mizrachi, S. Rambally, S. Akbar, and R. J. Auchus (2009)
Endocrinology 150, 4154-4162
 |  Abstract »  |  Full Text »  |  PDF »

ER membrane-localized oxidoreductase Ero1 is required for disulfide bond formation in the rice endosperm.

Y. Onda, T. Kumamaru, and Y. Kawagoe (2009)
PNAS 106, 14156-14161
 |  Abstract »  |  Full Text »  |  PDF »

Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency.

B. L. Schulz, C. U. Stirnimann, J. P. A. Grimshaw, M. S. Brozzo, F. Fritsch, E. Mohorko, G. Capitani, R. Glockshuber, M. G. Grutter, and M. Aebi (2009)
PNAS 106, 11061-11066
 |  Abstract »  |  Full Text »  |  PDF »

Reconstitution of Human Ero1-L{alpha}/Protein-Disulfide Isomerase Oxidative Folding Pathway in Vitro: POSITION-DEPENDENT DIFFERENCES IN ROLE BETWEEN THE a AND a' DOMAINS OF PROTEIN-DISULFIDE ISOMERASE.

L. Wang, S.-j. Li, A. Sidhu, L. Zhu, Y. Liang, R. B. Freedman, and C.-c. Wang (2009)
J. Biol. Chem. 284, 199-206
 |  Abstract »  |  Full Text »  |  PDF »

The Catalytic Activity of Protein-disulfide Isomerase Requires a Conformationally Flexible Molecule.

G. Tian, F.-X. Kober, U. Lewandrowski, A. Sickmann, W. J. Lennarz, and H. Schindelin (2008)
J. Biol. Chem. 283, 33630-33640
 |  Abstract »  |  Full Text »  |  PDF »

The Redox Environment in the Mitochondrial Intermembrane Space Is Maintained Separately from the Cytosol and Matrix.

J. Hu, L. Dong, and C. E. Outten (2008)
J. Biol. Chem. 283, 29126-29134
 |  Abstract »  |  Full Text »  |  PDF »

Radical-free biology of oxidative stress.

D. P. Jones (2008)
Am J Physiol Cell Physiol 295, C849-C868
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Redox Potential and Ca2+ on the Inositol 1,4,5-Trisphosphate Receptor L3-1 Loop Region: IMPLICATIONS FOR RECEPTOR REGULATION.

S. Kang, J. Kang, H. Kwon, D. Frueh, S. H. Yoo, G. Wagner, and S. Park (2008)
J. Biol. Chem. 283, 25567-25575
 |  Abstract »  |  Full Text »  |  PDF »

Saccharomyces cerevisiae Grx6 and Grx7 Are Monothiol Glutaredoxins Associated with the Early Secretory Pathway.

A. Izquierdo, C. Casas, U. Muhlenhoff, C. H. Lillig, and E. Herrero (2008)
Eukaryot. Cell 7, 1415-1426
 |  Abstract »  |  Full Text »  |  PDF »

The Torsin-family AAA+ Protein OOC-5 Contains a Critical Disulfide Adjacent to Sensor-II That Couples Redox State to Nucleotide Binding.

L. Zhu, J. O. Wrabl, A. P. Hayashi, L. S. Rose, and P. J. Thomas (2008)
Mol. Biol. Cell 19, 3599-3612
 |  Abstract »  |  Full Text »  |  PDF »

ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER.

R. Ushioda, J. Hoseki, K. Araki, G. Jansen, D. Y. Thomas, and K. Nagata (2008)
Science 321, 569-572
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Group of Glutaredoxins in the cis-Golgi Critical for Oxidative Stress Resistance.

N. Mesecke, A. Spang, M. Deponte, and J. M. Herrmann (2008)
Mol. Biol. Cell 19, 2673-2680
 |  Abstract »  |  Full Text »  |  PDF »

Islet Amyloid in Type 2 Diabetes, and the Toxic Oligomer Hypothesis.

L. Haataja, T. Gurlo, C. J. Huang, and P. C. Butler (2008)
Endocr. Rev. 29, 303-316
 |  Abstract »  |  Full Text »  |  PDF »

Role and Regulation of Iron-Sulfur Cluster Biosynthesis Genes in Shigella flexneri Virulence.

L. Runyen-Janecky, A. Daugherty, B. Lloyd, C. Wellington, H. Eskandarian, and M. Sagransky (2008)
Infect. Immun. 76, 1083-1092
 |  Abstract »  |  Full Text »  |  PDF »

Cellular redox state protects acetaldehyde-induced alteration in cardiomyocyte function by modifying Ca2+ release from sarcoplasmic reticulum.

T. Oba, Y. Maeno, M. Nagao, N. Sakuma, and T. Murayama (2008)
Am J Physiol Heart Circ Physiol 294, H121-H133
 |  Abstract »  |  Full Text »  |  PDF »

In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human Diseases.

D. N. Hebert and M. Molinari (2007)
Physiol Rev 87, 1377-1408
 |  Abstract »  |  Full Text »  |  PDF »

Intramolecular Disulfide Bond Is a Critical Check Point Determining Degradative Fates of ATP-binding Cassette (ABC) Transporter ABCG2 Protein.

K. Wakabayashi, H. Nakagawa, A. Tamura, S. Koshiba, K. Hoshijima, M. Komada, and T. Ishikawa (2007)
J. Biol. Chem. 282, 27841-27846
 |  Abstract »  |  Full Text »  |  PDF »

Sequential Opening of Mitochondrial Ion Channels as a Function of Glutathione Redox Thiol Status.

M. A. Aon, S. Cortassa, C. Maack, and B. O'Rourke (2007)
J. Biol. Chem. 282, 21889-21900
 |  Abstract »  |  Full Text »  |  PDF »

Prostaglandin Endoperoxide H Synthases: PEROXIDASE HYDROPEROXIDE SPECIFICITY AND CYCLOOXYGENASE ACTIVATION.

J. Liu, S. A. Seibold, C. J. Rieke, I. Song, R. I. Cukier, and W. L. Smith (2007)
J. Biol. Chem. 282, 18233-18244
 |  Abstract »  |  Full Text »  |  PDF »

Diverse Subcellular Locations of Cryptogein-Induced Reactive Oxygen Species Production in Tobacco Bright Yellow-2 Cells.

C. Ashtamker, V. Kiss, M. Sagi, O. Davydov, and R. Fluhr (2007)
Plant Physiology 143, 1817-1826
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Iron Binding Property of Two Putative Iron Donors for the Iron-Sulfur Cluster Assembly: IscA AND THE BACTERIAL FRATAXIN ORTHOLOG CyaY UNDER PHYSIOLOGICAL AND OXIDATIVE STRESS CONDITIONS.

H. Ding, J. Yang, L. C. Coleman, and S. Yeung (2007)
J. Biol. Chem. 282, 7997-8004
 |  Abstract »  |  Full Text »  |  PDF »

The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae.

D. Ganguli, C. Kumar, and A. K. Bachhawat (2007)
Genetics 175, 1137-1151
 |  Abstract »  |  Full Text »  |  PDF »

Zinc binding to the HCCH motif of HIV-1 virion infectivity factor induces a conformational change that mediates protein-protein interactions.

I. Paul, J. Cui, and E. L. Maynard (2006)
PNAS 103, 18475-18480
 |  Abstract »  |  Full Text »  |  PDF »

Insights into Deglutathionylation Reactions: DIFFERENT INTERMEDIATES IN THE GLUTAREDOXIN AND PROTEIN DISULFIDE ISOMERASE CATALYZED REACTIONS ARE DEFINED BY THE {gamma}-LINKAGE PRESENT IN GLUTATHIONE.

M. J. Peltoniemi, A.-R. Karala, J. K. Jurvansuu, V. L. Kinnula, and L. W. Ruddock (2006)
J. Biol. Chem. 281, 33107-33114
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging.

J. Yang, H. Chen, I. R. Vlahov, J.-X. Cheng, and P. S. Low (2006)
PNAS 103, 13872-13877
 |  Abstract »  |  Full Text »  |  PDF »

Mutations in the FAD Binding Domain Cause Stress-induced Misoxidation of the Endoplasmic Reticulum Oxidoreductase Ero1beta.

S. Dias-Gunasekara, M. van Lith, J. A. G. Williams, R. Kataky, and A. M. Benham (2006)
J. Biol. Chem. 281, 25018-25025
 |  Abstract »  |  Full Text »  |  PDF »

Changes of endoplasmic reticulum chaperone complexes, redox state, and impaired protein disulfide reductase activity in misfolding {alpha}1-antitrypsin transgenic mice.

E. Papp, P. Szaraz, T. Korcsmaros, and P. Csermely (2006)
FASEB J 20, 1018-1020
 |  Abstract »  |  Full Text »  |  PDF »

Uncoupled Redox Systems in the Lumen of the Endoplasmic Reticulum: PYRIDINE NUCLEOTIDES STAY REDUCED IN AN OXIDATIVE ENVIRONMENT.

S. Piccirella, I. Czegle, B. Lizak, E. Margittai, S. Senesi, E. Papp, M. Csala, R. Fulceri, P. Csermely, J. Mandl, et al. (2006)
J. Biol. Chem. 281, 4671-4677
 |  Abstract »  |  Full Text »  |  PDF »

The Thioredoxin System Protects Ribosomes against Stress-induced Aggregation.

J. D. Rand and C. M. Grant (2006)
Mol. Biol. Cell 17, 387-401
 |  Abstract »  |  Full Text »  |  PDF »

Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates.

C. D. Austin, X. Wen, L. Gazzard, C. Nelson, R. H. Scheller, and S. J. Scales (2005)
PNAS 102, 17987-17992
 |  Abstract »  |  Full Text »  |  PDF »

Scurvy Leads to Endoplasmic Reticulum Stress and Apoptosis in the Liver of Guinea Pigs.

E. Margittai, G. Banhegyi, A. Kiss, G. Nagy, J. Mandl, Z. Schaff, and M. Csala (2005)
J. Nutr. 135, 2530-2534
 |  Abstract »  |  Full Text »  |  PDF »

A Bacterial Glutathione Transporter (Escherichia coli CydDC) Exports Reductant to the Periplasm.

M. S. Pittman, H. C. Robinson, and R. K. Poole (2005)
J. Biol. Chem. 280, 32254-32261
 |  Abstract »  |  Full Text »  |  PDF »

Interactions among Yeast Protein-Disulfide Isomerase Proteins and Endoplasmic Reticulum Chaperone Proteins Influence Their Activities.

T. Kimura, Y. Hosoda, Y. Sato, Y. Kitamura, T. Ikeda, T. Horibe, and M. Kikuchi (2005)
J. Biol. Chem. 280, 31438-31441
 |  Abstract »  |  Full Text »  |  PDF »

Posttranslational Protein Modification in Archaea.

J. Eichler and M. W. W. Adams (2005)
Microbiol. Mol. Biol. Rev. 69, 393-425
 |  Abstract »  |  Full Text »  |  PDF »

Vitamin C biosynthesis in trypanosomes: A role for the glycosome.

S. R. Wilkinson, S. R. Prathalingam, M. C. Taylor, D. Horn, and J. M. Kelly (2005)
PNAS 102, 11645-11650
 |  Abstract »  |  Full Text »  |  PDF »

Delayed Mechanism for Induction of {gamma}-Glutamylcysteine Synthetase Heavy Subunit mRNA Stability by Oxidative Stress Involving p38 Mitogen-activated Protein Kinase Signaling.

I.-S. Song, S. Tatebe, W. Dai, and M. T. Kuo (2005)
J. Biol. Chem. 280, 28230-28240
 |  Abstract »  |  Full Text »  |  PDF »

Glutathionylation of Two Cysteine Residues in Paired Domain Regulates DNA Binding Activity of Pax-8.

X. Cao, F. Kambe, X. Lu, N. Kobayashi, S. Ohmori, and H. Seo (2005)
J. Biol. Chem. 280, 25901-25906
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Proatherogenic Events and Cell Adhesion Modulated by Extracellular Thiol/Disulfide Redox State.

Y.-M. Go and D. P. Jones (2005)
Circulation 111, 2973-2980
 |  Abstract »  |  Full Text »  |  PDF »

The Solution Structure of the FATC Domain of the Protein Kinase Target of Rapamycin Suggests a Role for Redox-dependent Structural and Cellular Stability.

S. A. Dames, J. M. Mulet, K. Rathgeb-Szabo, M. N. Hall, and S. Grzesiek (2005)
J. Biol. Chem. 280, 20558-20564
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Two Protein Disulfide Isomerases from the Endocytic Pathway of Bloodstream Forms of Trypanosoma brucei.

J. Rubotham, K. Woods, J. A. Garcia-Salcedo, E. Pays, and D. P. Nolan (2005)
J. Biol. Chem. 280, 10410-10418
 |  Abstract »  |  Full Text »  |  PDF »

Engineering of a Recombinant Vitamin K-dependent {gamma}-Carboxylation System with Enhanced {gamma}-Carboxyglutamic Acid Forming Capacity: EVIDENCE FOR A FUNCTIONAL CXXC REDOX CENTER IN THE SYSTEM.

N. Wajih, D. C. Sane, S. M. Hutson, and R. Wallin (2005)
J. Biol. Chem. 280, 10540-10547
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of a Novel Thioredoxin-related Transmembrane Protein of the Endoplasmic Reticulum.

J. Haugstetter, T. Blicher, and L. Ellgaard (2005)
J. Biol. Chem. 280, 8371-8380
 |  Abstract »  |  Full Text »  |  PDF »

Genetic and Environmental Factors Influencing Glutathione Homeostasis in Saccharomyces cerevisiae.

G. G. Perrone, C. M. Grant, and I. W. Dawes (2005)
Mol. Biol. Cell 16, 218-230
 |  Abstract »  |  Full Text »  |  PDF »

Glutathione Directly Reduces an Oxidoreductase in the Endoplasmic Reticulum of Mammalian Cells.

C. E. Jessop and N. J. Bulleid (2004)
J. Biol. Chem. 279, 55341-55347
 |  Abstract »  |  Full Text »  |  PDF »

Leishmania major Elongation Factor 1B Complex Has Trypanothione S-Transferase and Peroxidase Activity.

T. J. Vickers, S. Wyllie, and A. H. Fairlamb (2004)
J. Biol. Chem. 279, 49003-49009
 |  Abstract »  |  Full Text »  |  PDF »

The Unusually Stable Quaternary Structure of Human Cu,Zn-Superoxide Dismutase 1 Is Controlled by Both Metal Occupancy and Disulfide Status.

F. Arnesano, L. Banci, I. Bertini, M. Martinelli, Y. Furukawa, and T. V. O'Halloran (2004)
J. Biol. Chem. 279, 47998-48003
 |  Abstract »  |  Full Text »  |  PDF »

Glutathione Is Required to Regulate the Formation of Native Disulfide Bonds within Proteins Entering the Secretory Pathway.

S. Chakravarthi and N. J. Bulleid (2004)
J. Biol. Chem. 279, 39872-39879
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a quinone-sensitive redox switch in the ArcB sensor kinase.

R. Malpica, B. Franco, C. Rodriguez, O. Kwon, and D. Georgellis (2004)
PNAS 101, 13318-13323
 |  Abstract »  |  Full Text »  |  PDF »

Monitoring disulfide bond formation in the eukaryotic cytosol.

H. Ostergaard, C. Tachibana, and J. R. Winther (2004)
J. Cell Biol. 166, 337-345
 |  Abstract »  |  Full Text »  |  PDF »

Glutathione Limits Ero1-dependent Oxidation in the Endoplasmic Reticulum.

S. N. Molteni, A. Fassio, M. R. Ciriolo, G. Filomeni, E. Pasqualetto, C. Fagioli, and R. Sitia (2004)
J. Biol. Chem. 279, 32667-32673
 |  Abstract »  |  Full Text »  |  PDF »

A combined in vitro/bioinformatic investigation of redox regulatory mechanisms governing cell cycle progression.

J. E. Conour, W. V. Graham, and H. R. Gaskins (2004)
Physiol Genomics 18, 196-205
 |  Abstract »  |  Full Text »  |  PDF »

Stress, Protein (Mis)folding, and Signaling: The Redox Connection.

R. Sitia and S. N. Molteni (2004)
Sci. STKE 2004, pe27
 |  Abstract »  |  Full Text »  |  PDF »

Cooperativity between 11{beta}-Hydroxysteroid Dehydrogenase Type 1 and Hexose-6-phosphate Dehydrogenase in the Lumen of the Endoplasmic Reticulum.

G. Banhegyi, A. Benedetti, R. Fulceri, and S. Senesi (2004)
J. Biol. Chem. 279, 27017-27021
 |  Abstract »  |  Full Text »  |  PDF »

The Inhibitory Effect of Calumenin on the Vitamin K-dependent {gamma}-Carboxylation System: CHARACTERIZATION OF THE SYSTEM IN NORMAL AND WARFARIN-RESISTANT RATS.

N. Wajih, D. C. Sane, S. M. Hutson, and R. Wallin (2004)
J. Biol. Chem. 279, 25276-25283
 |  Abstract »  |  Full Text »  |  PDF »

Protein Disulfide Bond Formation in the Cytoplasm during Oxidative Stress.

R. C. Cumming, N. L. Andon, P. A. Haynes, M. Park, W. H. Fischer, and D. Schubert (2004)
J. Biol. Chem. 279, 21749-21758
 |  Abstract »  |  Full Text »  |  PDF »

Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators.

C. T. Dooley, T. M. Dore, G. T. Hanson, W. C. Jackson, S. J. Remington, and R. Y. Tsien (2004)
J. Biol. Chem. 279, 22284-22293
 |  Abstract »  |  Full Text »  |  PDF »

Investigating Mitochondrial Redox Potential with Redox-sensitive Green Fluorescent Protein Indicators.

G. T. Hanson, R. Aggeler, D. Oglesbee, M. Cannon, R. A. Capaldi, R. Y. Tsien, and S. J. Remington (2004)
J. Biol. Chem. 279, 13044-13053
 |  Abstract »  |  Full Text »  |  PDF »

A Major Fraction of Endoplasmic Reticulum-located Glutathione Is Present as Mixed Disulfides with Protein.

R. Bass, L. W. Ruddock, P. Klappa, and R. B. Freedman (2004)
J. Biol. Chem. 279, 5257-5262
 |  Abstract »  |  Full Text »  |  PDF »

Different Contributions of the Three CXXC Motifs of Human Protein-disulfide Isomerase-related Protein to Isomerase Activity and Oxidative Refolding.

T. Horibe, M. Gomi, D. Iguchi, H. Ito, Y. Kitamura, T. Masuoka, I. Tsujimoto, T. Kimura, and M. Kikuchi (2004)
J. Biol. Chem. 279, 4604-4611
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative protein folding in eukaryotes: mechanisms and consequences.

B. P. Tu and J. S. Weissman (2004)
J. Cell Biol. 164, 341-346
 |  Abstract »  |  Full Text »  |  PDF »

The Endoplasmic Reticulum Membrane Is Permeable to Small Molecules.

S. Le Gall, A. Neuhof, and T. Rapoport (2004)
Mol. Biol. Cell 15, 447-455
 |  Abstract »  |  Full Text »  |  PDF »

FAD Transport and FAD-dependent Protein Thiol Oxidation in Rat Liver Microsomes.

M. Varsanyi, A. Szarka, E. Papp, D. Makai, G. Nardai, R. Fulceri, P. Csermely, J. Mandl, A. Benedetti, and G. Banhegyi (2004)
J. Biol. Chem. 279, 3370-3374
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+-dependent redox modulation of SERCA 2b by ERp57.

Y. Li and P. Camacho (2004)
J. Cell Biol. 164, 35-46
 |  Abstract »  |  Full Text »  |  PDF »

Mining the Giardia lamblia Genome for New Cyst Wall Proteins.

C.-H. Sun, J. M. McCaffery, D. S. Reiner, and F. D. Gillin (2003)
J. Biol. Chem. 278, 21701-21708
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Mode of Polymerization of {alpha}1-Proteinase Inhibitor.

E. Marszal, D. Danino, and A. Shrake (2003)
J. Biol. Chem. 278, 19611-19618
 |  Abstract »  |  Full Text »  |  PDF »

In Vitro Refolding of Human Proinsulin. KINETIC INTERMEDIATES, PUTATIVE DISULFIDE-FORMING PATHWAY, FOLDING INITIATION SITE, AND POTENTIAL ROLE OF C-PEPTIDE IN FOLDING PROCESS.

Z.-S. Qiao, C.-Y. Min, Q.-X. Hua, M. A. Weiss, and Y.-M. Feng (2003)
J. Biol. Chem. 278, 17800-17809
 |  Abstract »  |  Full Text »  |  PDF »

A fluorescence resonance energy transfer sensor for the beta -domain of metallothionein.

S.-H. Hong and W. Maret (2003)
PNAS 100, 2255-2260
 |  Abstract »  |  Full Text »  |  PDF »

Redox regulation and storage processes during maturation in kernels of Triticum durum.

L. De Gara, M. C. de Pinto, V. M. C. Moliterni, and M. G. D'Egidio (2003)
J. Exp. Bot. 54, 249-258
 |  Abstract »  |  Full Text »  |  PDF »

H2O2 activates ryanodine receptor but has little effect on recovery of releasable Ca2+ content after fatigue.

T. Oba, C. Kurono, R. Nakajima, T. Takaishi, K. Ishida, G. A. Fuller, W. Klomkleaw, and M. Yamaguchi (2002)
J Appl Physiol 93, 1999-2008
 |  Abstract »  |  Full Text »  |  PDF »

Pink-eyed Dilution Protein Modulates Arsenic Sensitivity and Intracellular Glutathione Metabolism.

L. Staleva, P. Manga, and S. J. Orlow (2002)
Mol. Biol. Cell 13, 4206-4220
 |  Abstract »  |  Full Text »  |  PDF »

Trypanosoma cruzi expresses a plant-like ascorbate-dependent hemoperoxidase localized to the endoplasmic reticulum.

S. R. Wilkinson, S. O. Obado, I. L. Mauricio, and J. M. Kelly (2002)
PNAS 99, 13453-13458
 |  Abstract »  |  Full Text »  |  PDF »

Membrane Localization and Topology of Leukotriene C4 Synthase.

P. Christmas, B. M. Weber, M. McKee, D. Brown, and R. J. Soberman (2002)
J. Biol. Chem. 277, 28902-28908
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Chromosomal Shigella flexneri Genes Induced by the Eukaryotic Intracellular Environment.

L. J. Runyen-Janecky and S. M. Payne (2002)
Infect. Immun. 70, 4379-4388
 |  Abstract »  |  Full Text »  |  PDF »

S-Nitrosohemoglobin Is Unstable in the Reductive Erythrocyte Environment and Lacks O2/NO-linked Allosteric Function.

M. T. Gladwin, X. Wang, C. D. Reiter, B. K. Yang, E. X. Vivas, C. Bonaventura, and A. N. Schechter (2002)
J. Biol. Chem. 277, 27818-27828
 |  Abstract »  |  Full Text »  |  PDF »

Genomic evidence that the intracellular proteins of archaeal microbes contain disulfide bonds.

P. Mallick, D. R. Boutz, D. Eisenberg, and T. O. Yeates (2002)
PNAS 99, 9679-9684
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Glutathionylation of human thioredoxin: A possible crosstalk between the glutathione and thioredoxin systems.

S. Casagrande, V. Bonetto, M. Fratelli, E. Gianazza, I. Eberini, T. Massignan, M. Salmona, G. Chang, A. Holmgren, and P. Ghezzi (2002)
PNAS 99, 9745-9749
 |  Abstract »  |  Full Text »  |  PDF »

Biochemical Characterization of Aspartyl Phosphate Phosphatase Interaction with a Phosphorylated Response Regulator and Its Inhibition by a Pentapeptide.

S. Ishikawa, L. Core, and M. Perego (2002)
J. Biol. Chem. 277, 20483-20489
 |  Abstract »  |  Full Text »  |  PDF »

Formation of Disulfide Bridges by a Single-chain Fv Antibody in the Reducing Ectopic Environment of the Plant Cytosol.

A. Schouten, J. Roosien, J. Bakker, and A. Schots (2002)
J. Biol. Chem. 277, 19339-19345
 |  Abstract »  |  Full Text »  |  PDF »

Repression of photosynthesis gene expression by formation of a disulfide bond in CrtJ.

S. Masuda, C. Dong, D. Swem, A. T. Setterdahl, D. B. Knaff, and C. E. Bauer (2002)
PNAS 99, 7078-7083
 |  Abstract »  |  Full Text »  |  PDF »

Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes.

M. Fratelli, H. Demol, M. Puype, S. Casagrande, I. Eberini, M. Salmona, V. Bonetto, M. Mengozzi, F. Duffieux, E. Miclet, et al. (2002)
PNAS 99, 3505-3510
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for an initiation site for hen lysozyme folding from the reduced form using its dissected peptide fragments.

T. Ohkuri, T. Ueda, M. Tsurumaru, and T. Imoto (2001)
Protein Eng. Des. Sel. 14, 829-833
 |  Abstract »  |  Full Text »  |  PDF »

Rearrangement of Nicotinic Receptor {alpha} Subunits during Formation of the Ligand Binding Sites.

M. Mitra, C. P. Wanamaker, and W. N. Green (2001)
J. Neurosci. 21, 3000-3008
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of residues and sequences of the carbohydrate recognition domain required for cell surface localization and ligand binding of human lectin-like oxidized LDL receptor.

X Shi, S Niimi, T Ohtani, and S Machida (2001)
J. Cell Sci. 114, 1273-1282
 |  Abstract »  |  PDF »

Reactive oxygen species in cell signaling.

V. J. Thannickal and B. L. Fanburg (2000)
Am J Physiol Lung Cell Mol Physiol 279, L1005-L1028
 |  Abstract »  |  Full Text »  |  PDF »

Biochemical Basis of Oxidative Protein Folding in the Endoplasmic Reticulum.

B. P. Tu, S. C. Ho-Schleyer, K. J. Travers, and J. S. Weissman (2000)
Science 290, 1571-1574
 |  Abstract »  |  Full Text »

Biogenesis of the Chloroplast-Encoded D1 Protein: Regulation of Translation Elongation, Insertion, and Assembly into Photosystem II.

L. Zhang, V. Paakkarinen, K. J. van Wijk, and E.-M. Aro (2000)
PLANT CELL 12, 1769-1782
 |  Abstract »  |  Full Text »

Glutathione synthesis is essential for mouse development but not for cell growth in culture.

Z.-Z. Shi, J. Osei-Frimpong, G. Kala, S. V. Kala, R. J. Barrios, G. M. Habib, D. J. Lukin, C. M. Danney, M. M. Matzuk, and M. W. Lieberman (2000)
PNAS 97, 5101-5106
 |  Abstract »  |  Full Text »  |  PDF »

The Function of Zinc Metallothionein: A Link between Cellular Zinc and Redox State.

W. Maret (2000)
J. Nutr. 130, 1455S-1458
 |  Abstract »  |  Full Text »

Hgt1p, a High Affinity Glutathione Transporter from the Yeast Saccharomyces cerevisiae.

A. Bourbouloux, P. Shahi, A. Chakladar, S. Delrot, and A. K. Bachhawat (2000)
J. Biol. Chem. 275, 13259-13265
 |  Abstract »  |  Full Text »  |  PDF »

Specific Chaperone-like Activity of Inhibitor of Caspase-activated DNase for Caspase-activated DNase.

H. Sakahira, A. Iwamatsu, and S. Nagata (2000)
J. Biol. Chem. 275, 8091-8096
 |  Abstract »  |  Full Text »  |  PDF »

Disulfide Bonds and Membrane Topology of the Vaccinia Virus A17L Envelope Protein.

T. Betakova and B. Moss (2000)
J. Virol. 74, 2438-2442
 |  Abstract »  |  Full Text »

Detoxification of Arsenic by Phytochelatins in Plants.

M. E.V. Schmoger, M. Oven, and E. Grill (2000)
Plant Physiology 122, 793-802
 |  Abstract »  |  Full Text »  |  PDF »

ERO1-L, a Human Protein That Favors Disulfide Bond Formation in the Endoplasmic Reticulum.

A. Cabibbo, M. Pagani, M. Fabbri, M. Rocchi, M. R. Farmery, N. J. Bulleid, and R. Sitia (2000)
J. Biol. Chem. 275, 4827-4833
 |  Abstract »  |  Full Text »  |  PDF »

Yeast flavin-containing monooxygenase is induced by the unfolded protein response.

J.-K. Suh and J. D. Robertus (2000)
PNAS 97, 121-126
 |  Abstract »  |  Full Text »  |  PDF »

Novel Protein-disulfide Isomerases from the Early-diverging Protist Giardia lamblia.

L. A. Knodler, R. Noiva, K. Mehta, J. M. McCaffery, S. B. Aley, S. G. Svard, T. G. Nystul, D. S. Reiner, J. D. Silberman, and F. D. Gillin (1999)
J. Biol. Chem. 274, 29805-29811
 |  Abstract »  |  Full Text »  |  PDF »

Selection of antibodies for intracellular function using a two-hybrid in vivo system.

M. Visintin, E. Tse, H. Axelson, T. H. Rabbitts, and A. Cattaneo (1999)
PNAS 96, 11723-11728
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of glutathione reductase extends survival in transgenic Drosophila melanogaster under hyperoxia but not normoxia.

R. J. MOCKETT, R. S. SOHAL, and W. C. ORR (1999)
FASEB J 13, 1733-1742
 |  Abstract »  |  Full Text »

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