Science 17 July 1992: Vol. 257. no. 5068, pp. 387 - 389 DOI: 10.1126/science.1631560

Prev | Table of Contents | Next

Articles

IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction.

M. Wang, J. Tan, Y. Wang, K. K. Meldrum, C. A. Dinarello, and D. R. Meldrum (2009)
PNAS 106, 17499-17504
 |  Abstract »  |  Full Text »  |  PDF »

Off-Pump Coronary Surgery causes Immediate Release of Myocardial Damage Markers.

I. Karu, P. Tahepold, T. A. Sulling, M. Alver, M. Zilmer, and J. Starkopf (2009)
Asian Cardiovasc Thorac Ann 17, 494-499
 |  Abstract »  |  Full Text »  |  PDF »

Role of Pro-/Anti-Inflammatory Cytokines and Their Correlation With Established Risk Factors in South Indians With Coronary Artery Disease.

M. Rajappa, S.K. Sen, and A. Sharma (2009)
Angiology 60, 419-426
 |  Abstract »  |  PDF »

sGC{alpha}1{beta}1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models.

E. S. Buys, A. Cauwels, M. J. Raher, J. J. Passeri, I. Hobai, S. M. Cawley, K. M. Rauwerdink, H. Thibault, P. Y. Sips, R. Thoonen, et al. (2009)
Am J Physiol Heart Circ Physiol 297, H654-H663
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Hemodynamic Patterns of Septic Shock at Presentation to Pediatric Intensive Care.

J. Brierley and M. J. Peters (2008)
Pediatrics 122, 752-759
 |  Abstract »  |  Full Text »  |  PDF »

TNFR1 signaling resistance associated with female stem cell cytokine production is independent of TNFR2-mediated pathways.

T. A. Markel, P. R. Crisostomo, M. Wang, Y. Wang, T. Lahm, N. M. Novotny, J. Tan, and D. R. Meldrum (2008)
Am J Physiol Regulatory Integrative Comp Physiol 295, R1124-R1130
 |  Abstract »  |  Full Text »  |  PDF »

Identification and physiological activity of survival factor released from cardiomyocytes during ischaemia and reperfusion.

Y. Mizukami, K. Ono, C.-K. Du, T. Aki, N. Hatano, Y. Okamoto, Y. Ikeda, H. Ito, K. Hamano, and S. Morimoto (2008)
Cardiovasc Res 79, 589-599
 |  Abstract »  |  Full Text »  |  PDF »

S100A8 and S100A9 Mediate Endotoxin-Induced Cardiomyocyte Dysfunction via the Receptor for Advanced Glycation End Products.

J. H. Boyd, B. Kan, H. Roberts, Y. Wang, and K. R. Walley (2008)
Circ. Res. 102, 1239-1246
 |  Abstract »  |  Full Text »  |  PDF »

Effects of IL-10 and age on IL-6, IL-1{beta}, and TNF-{alpha} responses in mouse skeletal and cardiac muscle to an acute inflammatory insult.

B. M. Meador, C. P. Krzyszton, R. W. Johnson, and K. A. Huey (2008)
J Appl Physiol 104, 991-997
 |  Abstract »  |  Full Text »  |  PDF »

Sepsis is associated with an upregulation of functional {beta}3 adrenoceptors in the myocardium.

S. Moniotte, C. Belge, B. Sekkali, P.B. Massion, B. Rozec, C. Dessy, and J.-L. Balligand (2007)
Eur J Heart Fail 9, 1163-1171
 |  Abstract »  |  Full Text »  |  PDF »

Lysozyme, a mediator of sepsis, impairs the cardiac neural adrenergic response by nonendothelial release of NO and inhibitory G protein signaling.

S. N. Mink, Z.-Q. Cheng, R. Bose, H. Jacobs, K. Kasian, D. E. Roberts, L. E. Santos-Martinez, and R. B. Light (2007)
Am J Physiol Heart Circ Physiol 293, H3140-H3149
 |  Abstract »  |  Full Text »  |  PDF »

Inducible NO synthase expression in endomyocardial biopsies after heart transplantation in relation to the postoperative course.

A. Koch, A. Burgschweiger, E. Herpel, F.-U. Sack, P. Schirmacher, G. B. Szabo, M. Karck, and P. A. Schnabel (2007)
Eur. J. Cardiothorac. Surg. 32, 639-643
 |  Abstract »  |  Full Text »  |  PDF »

Sepsis and the Heart.

M.W. Merx and C. Weber (2007)
Circulation 116, 793-802
 |  Abstract »  |  Full Text »  |  PDF »

Tumor necrosis factor-{alpha} is toxic via receptor 1 and protective via receptor 2 in a murine model of myocardial infarction.

Y. Monden, T. Kubota, T. Inoue, T. Tsutsumi, S. Kawano, T. Ide, H. Tsutsui, and K. Sunagawa (2007)
Am J Physiol Heart Circ Physiol 293, H743-H753
 |  Abstract »  |  Full Text »  |  PDF »

TNF-{alpha} blockade decreases oxidative stress in the paraventricular nucleus and attenuates sympathoexcitation in heart failure rats.

A. Guggilam, M. Haque, E. K. Kerut, E. McIlwain, P. Lucchesi, I. Seghal, and J. Francis (2007)
Am J Physiol Heart Circ Physiol 293, H599-H609
 |  Abstract »  |  Full Text »  |  PDF »

Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study.

V. Dzavik, G. Cotter, H. R. Reynolds, J. H. Alexander, K. Ramanathan, A. L. Stebbins, D. Hathaway, M. E. Farkouh, E. M. Ohman, D. A. Baran, et al. (2007)
Eur. Heart J. 28, 1109-1116
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide-dependent and -independent mechanisms are involved in TNF-{alpha}-induced depression of cardiac myocyte contractility.

A. Kumar, B. Paladugu, J. Mensing, A. Kumar, and J. E. Parrillo (2007)
Am J Physiol Regulatory Integrative Comp Physiol 292, R1900-R1906
 |  Abstract »  |  Full Text »  |  PDF »

Role of interleukin-6 in cardiac inflammation and dysfunction after burn complicated by sepsis.

H. Zhang, H.-Y. Wang, R. Bassel-Duby, D. L. Maass, W. E. Johnston, J. W. Horton, and W. Tao (2007)
Am J Physiol Heart Circ Physiol 292, H2408-H2416
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency of TNFR1 protects myocardium through SOCS3 and IL-6 but not p38 MAPK or IL-1beta.

M. Wang, T. Markel, P. Crisostomo, C. Herring, K. K. Meldrum, K. D. Lillemoe, and D. R. Meldrum (2007)
Am J Physiol Heart Circ Physiol 292, H1694-H1699
 |  Abstract »  |  Full Text »  |  PDF »

Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine.

Z. Guo, Z. Xia, J. Jiang, and J. H. McNeill (2007)
Am J Physiol Heart Circ Physiol 292, H1728-H1736
 |  Abstract »  |  Full Text »  |  PDF »

Soluble TNF receptors prevent apoptosis in infiltrating cells and promote ventricular rupture and remodeling after myocardial infarction.

Y. Monden, T. Kubota, T. Tsutsumi, T. Inoue, S. Kawano, N. Kawamura, T. Ide, K. Egashira, H. Tsutsui, and K. Sunagawa (2007)
Cardiovasc Res 73, 794-805
 |  Abstract »  |  Full Text »  |  PDF »

Effects of burn injury on myocardial signaling and cytokine secretion: possible role of PKC.

J. Tan, D. L. Maass, D. J. White, and J. W. Horton (2007)
Am J Physiol Regulatory Integrative Comp Physiol 292, R887-R896
 |  Abstract »  |  Full Text »  |  PDF »

Left bundle branch block as a risk factor for progression to heart failure.

F. Zannad, E. Huvelle, K. Dickstein, D. J. van Veldhuisen, C. Stellbrink, L. Kober, S. Cazeau, P. Ritter, A. P. Maggioni, R. Ferrari, et al. (2007)
Eur J Heart Fail 9, 7-14
 |  Abstract »  |  Full Text »  |  PDF »

Prevention of TNFalpha-associated myocardial dysfunction resulting from cardiopulmonary bypass and cardioplegic arrest by glucocorticoid treatment..

O. J. Liakopoulos, N. Teucher, C. Muhlfeld, P. Middel, G. Heusch, F. A. Schoendube, and H. Dorge (2006)
Eur. J. Cardiothorac. Surg. 30, 263-270
 |  Abstract »  |  Full Text »  |  PDF »

Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis.

L. Szalay, T. Shimizu, T. Suzuki, Y.-C. Hsieh, M. A. Choudhry, M. G. Schwacha, K. I. Bland, and I. H. Chaudry (2006)
Am J Physiol Gastrointest Liver Physiol 291, G260-G266
 |  Abstract »  |  Full Text »  |  PDF »

Redox regulation of cardiac calcium channels and transporters.

A. V. Zima and L. A. Blatter (2006)
Cardiovasc Res 71, 310-321
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Necrosis Factor Receptor 1 Signaling Resistance in the Female Myocardium During Ischemia.

M. Wang, B. M. Tsai, P. R. Crisostomo, and D. R. Meldrum (2006)
Circulation 114, I-282-I-289
 |  Abstract »  |  Full Text »  |  PDF »

Relationship between cytokines and tumour markers in patients with chronic heart failure.

F. Kosar, Y. Aksoy, G. Ozguntekin, I. Ozerol, and E. Varol (2006)
Eur J Heart Fail 8, 270-274
 |  Abstract »  |  Full Text »  |  PDF »

Electrical remodeling of cardiac myocytes from mice with heart failure due to the overexpression of tumor necrosis factor-{alpha}.

P. S. Petkova-Kirova, E. Gursoy, H. Mehdi, C. F. McTiernan, B. London, and G. Salama (2006)
Am J Physiol Heart Circ Physiol 290, H2098-H2107
 |  Abstract »  |  Full Text »  |  PDF »

IL-6 induces PI 3-kinase and nitric oxide-dependent protection and preserves mitochondrial function in cardiomyocytes.

N. Smart, M. H. Mojet, D. S. Latchman, M. S. Marber, M. R. Duchen, and R. J. Heads (2006)
Cardiovasc Res 69, 164-177
 |  Abstract »  |  Full Text »  |  PDF »

p38 Mitogen Activated Protein Kinase Mediates Both Death Signaling and Functional Depression in the Heart.

M. Wang, B. M. Tsai, M. W. Turrentine, Y. Mahomed, J. W. Brown, and D. R. Meldrum (2005)
Ann. Thorac. Surg. 80, 2235-2241
 |  Abstract »  |  Full Text »  |  PDF »

Effects of combined administration of low dose atorvastatin and vitamin E on inflammatory markers and endothelial function in patients with heart failure.

D. Tousoulis, C. Antoniades, C. Vassiliadou, M. Toutouza, C. Pitsavos, C. Tentolouris, A. Trikas, and C. Stefanadis (2005)
Eur J Heart Fail 7, 1126-1132
 |  Abstract »  |  Full Text »  |  PDF »

MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in rats.

M. Nimata, T.-a. Okabe, M. Hattori, Z. Yuan, K. Shioji, and C. Kishimoto (2005)
Am J Physiol Heart Circ Physiol 289, H2514-H2518
 |  Abstract »  |  Full Text »  |  PDF »

Type 5 Phosphodiesterase Inhibition: The Focus Shifts to the Heart.

M. J. Semigran (2005)
Circulation 112, 2589-2591
 |  Full Text »  |  PDF »

Cytokines and cardiovascular disease.

V. C. Mehra, V. S. Ramgolam, and J. R. Bender (2005)
J. Leukoc. Biol. 78, 805-818
 |  Abstract »  |  Full Text »  |  PDF »

Tumor necrosis factor-a, biologic agents and cardiovascular risk.

P Sarzi-Puttini, F Atzeni, A Doria, L Iaccarino, and M Turiel (2005)
Lupus 14, 780-784
 |  Abstract »  |  PDF »

Inflammatory cytokines in pediatric cardiac surgery and variable effect of the hemofiltration process.

G. Brancaccio, E. Villa, E. Girolami, G. Michielon, C. Feltri, E. Mazzera, D. Costa, G. Isacchi, E. Iannace, A. Amodeo, et al. (2005)
Perfusion 20, 263-268
 |  Abstract »  |  PDF »

Mechanisms of Cardiac Depression Caused by Lipoteichoic Acids From Staphylococcus aureus in Isolated Rat Hearts.

U. Grandel, M. Hopf, M. Buerke, K. Hattar, M. Heep, L. Fink, R. M. Bohle, S. Morath, T. Hartung, S. Pullamsetti, et al. (2005)
Circulation 112, 691-698
 |  Abstract »  |  Full Text »  |  PDF »

Peroxynitrite-induced {alpha}-actinin nitration and contractile alterations in isolated human myocardial cells.

A. Borbely, A. Toth, I. Edes, L. Virag, J. G. Papp, A. Varro, W. J. Paulus, J. van der Velden, G. J.M. Stienen, and Z. Papp (2005)
Cardiovasc Res 67, 225-233
 |  Abstract »  |  Full Text »  |  PDF »

Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice.

P. R. Woldbaek, J. B. Sande, T. A. Stromme, P. K. Lunde, S. Djurovic, T. Lyberg, G. Christensen, and T. Tonnessen (2005)
Am J Physiol Heart Circ Physiol 289, H708-H714
 |  Abstract »  |  Full Text »  |  PDF »

Pentoxifylline attenuates cardiac dysfunction and reduces TNF-{alpha} level in ischemic-reperfused heart.

M. Zhang, Y.-J. Xu, H. K. Saini, B. Turan, P. P. Liu, and N. S. Dhalla (2005)
Am J Physiol Heart Circ Physiol 289, H832-H839
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of sarcoplasmic reticular function by chronic interleukin-6 exposure via iNOS in adult ventricular myocytes.

X.-W. Yu, Q. Chen, R. H Kennedy, and S. J Liu (2005)
J. Physiol. 566, 327-340
 |  Abstract »  |  Full Text »  |  PDF »

Both cGMP and peroxynitrite mediate chronic interleukin-6-induced negative inotropy in adult rat ventricular myocytes.

X.-W. Yu, M.-Y. G Liu, R. H Kennedy, and S. J Liu (2005)
J. Physiol. 566, 341-353
 |  Abstract »  |  Full Text »  |  PDF »

Myocardial cytokine gene expression is higher in aortic stenosis than in idiopathic dilated cardiomyopathy.

M Vanderheyden, W J Paulus, M Voss, P Knuefermann, N Sivasubramanian, D Mann, and G Baumgarten (2005)
Heart 91, 926-931
 |  Abstract »  |  Full Text »  |  PDF »

Soluble CD40 ligand in acute and chronic heart failure.

T. Ueland, P. Aukrust, A. Yndestad, K. Otterdal, S. S. Froland, K. Dickstein, J. Kjekshus, L. Gullestad, and J. K. Damas (2005)
Eur. Heart J. 26, 1101-1107
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of NF-{kappa}B improves cardiac function and survival without affecting inflammation in TNF-{alpha}-induced cardiomyopathy.

N. Kawamura, T. Kubota, S. Kawano, Y. Monden, A. M. Feldman, H. Tsutsui, A. Takeshita, and K. Sunagawa (2005)
Cardiovasc Res 66, 520-529
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-6 Causes Myocardial Failure and Skeletal Muscle Atrophy in Rats.

S. P.M. Janssen, G. Gayan-Ramirez, A. Van Den Bergh, P. Herijgers, K. Maes, E. Verbeken, and M. Decramer (2005)
Circulation 111, 996-1005
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-18 Is a Pro-hypertrophic Cytokine That Acts through a Phosphatidylinositol 3-Kinase-Phosphoinositide-dependent Kinase-1-Akt-GATA4 Signaling Pathway in Cardiomyocytes.

B. Chandrasekar, S. Mummidi, W. C. Claycomb, R. Mestril, and M. Nemer (2005)
J. Biol. Chem. 280, 4553-4567
 |  Abstract »  |  Full Text »  |  PDF »

Sex differences in the myocardial inflammatory response to ischemia-reperfusion injury.

M. Wang, L. Baker, B. M. Tsai, K. K. Meldrum, and D. R. Meldrum (2005)
Am J Physiol Endocrinol Metab 288, E321-E326
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine-Induced Modulation of Cardiac Function.

S. D. Prabhu (2004)
Circ. Res. 95, 1140-1153
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism of cardiac depression after trauma-hemorrhage: increased cardiomyocyte IL-6 and effect of sex steroids on IL-6 regulation and cardiac function.

S. Yang, R. Zheng, S. Hu, Y. Ma, M. A. Choudhry, J. L. Messina, L. W. Rue III, K. I. Bland, and I. H. Chaudry (2004)
Am J Physiol Heart Circ Physiol 287, H2183-H2191
 |  Abstract »  |  Full Text »  |  PDF »

Restrictive filling pattern is associated with increased humoral activation and impaired exercise capacity in dilated cardiomyopathy.

A. P. Patrianakos, F. I. Parthenakis, E. A. Papadimitriou, G. F. Diakakis, P. G. Tzerakis, D. Nikitovic, and P. E. Vardas (2004)
Eur J Heart Fail 6, 735-743
 |  Abstract »  |  Full Text »  |  PDF »

Effects of a novel immune modulation therapy in patients with advanced chronic heart failure: Results of a randomized, controlled, phase II trial.

G. Torre-Amione, F. Sestier, B. Radovancevic, and J. Young (2004)
J. Am. Coll. Cardiol. 44, 1181-1186
 |  Abstract »  |  Full Text »  |  PDF »

Peroxynitrite decomposition catalysts prevent myocardial dysfunction and inflammation in endotoxemic rats.

S. Lancel, S. Tissier, S. Mordon, X. Marechal, F. Depontieu, A. Scherpereel, C. Chopin, and R. Neviere (2004)
J. Am. Coll. Cardiol. 43, 2348-2358
 |  Abstract »  |  Full Text »  |  PDF »

Beating heart revascularization with or without cardiopulmonary bypass: Evaluation of inflammatory response in a prospective randomized study.

I. Y. P. Wan, A. A. Arifi, S. Wan, J. H. Y. Yip, A. D. L. Sihoe, K.H. Thung, E. M. C. Wong, and A. P. C. Yim (2004)
J. Thorac. Cardiovasc. Surg. 127, 1624-1631
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Intrinsic and Extrinsic Proapoptotic Signaling Pathways in Interleukin-18-mediated Human Cardiac Endothelial Cell Death.

B. Chandrasekar, K. Vemula, R. M. Surabhi, M. Li-Weber, L. B. Owen-Schaub, L. E. Jensen, and S. Mummidi (2004)
J. Biol. Chem. 279, 20221-20233
 |  Abstract »  |  Full Text »  |  PDF »

Angiotensin II Type 1a Receptor Is Involved in Cell Infiltration, Cytokine Production, and Neovascularization in Infarcted Myocardium.

H. Toko, Y. Zou, T. Minamino, M. Sakamoto, M. Sano, M. Harada, T. Nagai, T. Sugaya, F. Terasaki, Y. Kitaura, et al. (2004)
Arterioscler Thromb Vasc Biol 24, 664-670
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide-cGMP pathway is involved in endotoxin-induced contractile dysfunction in rat hearts.

T. Tatsumi, N. Keira, K. Akashi, M. Kobara, S. Matoba, J. Shiraishi, S. Yamanaka, A. Mano, M. Takeda, S. Nishikawa, et al. (2004)
J Appl Physiol 96, 853-860
 |  Abstract »  |  Full Text »  |  PDF »

Role of Corticosteroids in Septic Shock.

L. D Burry and R. S Wax (2004)
Ann. Pharmacother. 38, 464-472
 |  Abstract »  |  Full Text »  |  PDF »

Therapy of Ischemic Cardiomyopathy With the Immunomodulating Agent Pentoxifylline: Results of a Randomized Study.

K. Sliwa, A. Woodiwiss, V. N. Kone, G. Candy, D. Badenhorst, G. Norton, C. Zambakides, F. Peters, and R. Essop (2004)
Circulation 109, 750-755
 |  Abstract »  |  Full Text »  |  PDF »

Strategies for Developing Biomarkers of Heart Failure.

S. A. Jortani, S. D. Prabhu, and R. Valdes Jr (2004)
Clin. Chem. 50, 265-278
 |  Abstract »  |  Full Text »  |  PDF »

Hypoxia-induced left ventricular dysfunction in myoglobin-deficient mice.

P. P. A. Mammen, S. B. Kanatous, I. S. Yuhanna, P. W. Shaul, M. G. Garry, R. S. Balaban, and D. J. Garry (2003)
Am J Physiol Heart Circ Physiol 285, H2132-H2141
 |  Abstract »  |  Full Text »  |  PDF »

Intra-amniotic lipopolysaccharide leads to fetal cardiac dysfunction: A mouse model for fetal inflammatory response.

S. Rounioja, J. Rasanen, V. Glumoff, M. Ojaniemi, K. Makikallio, and M. Hallman (2003)
Cardiovasc Res 60, 156-164
 |  Abstract »  |  Full Text »  |  PDF »

Obstructive Sleep Apnea: Implications for Cardiac and Vascular Disease.

A. S. M. Shamsuzzaman, B. J. Gersh, and V. K. Somers (2003)
JAMA 290, 1906-1914
 |  Abstract »  |  Full Text »  |  PDF »

Effect of tumor necrosis Factor-Alphaon endothelial and inducible nitric oxidesynthase messenger ribonucleic acidexpression and nitric oxide synthesisin ischemic and nonischemic isolated rat heart.

Y. Paz, I. Frolkis, D. Pevni, I. Shapira, Y. Yuhas, A. Iaina, Y. Wollman, T. Chernichovski, N. Nesher, C. Locker, et al. (2003)
J. Am. Coll. Cardiol. 42, 1299-1305
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Necrosis Factor Gene Polymorphism Is Associated with Enhanced Systemic Inflammatory Response and Increased Cardiopulmonary Morbidity After Cardiac Surgery.

H. Tomasdottir, H. Hjartarson, A. Ricksten, C. Wasslavik, A. Bengtsson, and S.-E. Ricksten (2003)
Anesth. Analg. 97, 944-949
 |  Abstract »  |  Full Text »  |  PDF »

Plasma levels of interleukin-8 and expression of interleukin-8 receptors on circulating neutrophils and monocytes after cardiopulmonary bypass in children.

P. Gessler, J. Pfenninger, J.-P. Pfammatter, T. Carrel, O. Baenziger, and C. Dahinden (2003)
J. Thorac. Cardiovasc. Surg. 126, 718-725
 |  Abstract »  |  Full Text »  |  PDF »

Carvedilol, a new antioxidative {beta}-blocker, blocks in vitro human peripheral blood T cell activation by downregulating NF-{kappa}B activity.

S.-P. Yang, L.-J. Ho, Y.-L. Lin, S.-M. Cheng, T.-P. Tsao, D.-M. Chang, Y.-L. Hsu, C.-Y. Shih, T.-Y. Juan, and J.-H. Lai (2003)
Cardiovasc Res 59, 776-787
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-2 Increases Activity of Sarcoplasmic Reticulum Ca2+-ATPase, but Decreases Its Sensitivity to Calcium in Rat Cardiomyocytes.

C.-M. Cao, Q. Xia, I. C. Bruce, X. Zhang, C. Fu, and J.-Z. Chen (2003)
J. Pharmacol. Exp. Ther. 306, 572-580
 |  Abstract »  |  Full Text »  |  PDF »

The prognostic value of circulating soluble cell adhesion molecules in patients with chronic congestive heart failure.

W.-H. Yin, J.-W. Chen, H.-L. Jen, M.-C. Chiang, W.-P. Huang, A.-N. Feng, S.-J. Lin, and M. S. Young (2003)
Eur J Heart Fail 5, 507-516
 |  Abstract »  |  Full Text »  |  PDF »

ASK1 Associates with Troponin T and Induces Troponin T Phosphorylation and Contractile Dysfunction in Cardiomyocytes.

X. He, Y. Liu, V. Sharma, R. T. Dirksen, R. Waugh, S.-S. Sheu, and W. Min (2003)
Am. J. Pathol. 163, 243-251
 |  Abstract »  |  Full Text »  |  PDF »

Acute Inhibition of Myoglobin Impairs Contractility and Energy State of iNOS-Overexpressing Hearts.

C. Wunderlich, U. Flogel, A. Godecke, J. Heger, and J. Schrader (2003)
Circ. Res. 92, 1352-1358
 |  Abstract »  |  Full Text »  |  PDF »

Intramyocardial synthesis of pro- and anti-inflammatory cytokines in infants with congenital cardiac defects.

M. Qing, K. Schumacher, R. Heise, M. Woltje, J. F. Vazquez-Jimenez, T. Richter, M. Arranda-Carrero, J. Hess, G.o. von Bernuth, and M.-C. Seghaye (2003)
J. Am. Coll. Cardiol. 41, 2266-2274
 |  Abstract »  |  Full Text »  |  PDF »

Dietary Magnesium Intake Influences Circulating Pro-Inflammatory Neuropeptide Levels and Loss of Myocardial Tolerance to Postischemic Stress.

J. H. Kramer, I. T. Mak, T. M. Phillips, and W. B. Weglicki (2003)
Experimental Biology and Medicine 228, 665-673
 |  Abstract »  |  Full Text »  |  PDF »

Increased myocardial oxygen consumption by TNF-alpha is mediated by a sphingosine signaling pathway.

U. Hofmann, E. Domeier, S. Frantz, M. Laser, B. Weckler, P. Kuhlencordt, S. Heuer, B. Keweloh, G. Ertl, and A. W. Bonz (2003)
Am J Physiol Heart Circ Physiol 284, H2100-H2105
 |  Abstract »  |  Full Text »  |  PDF »

JAK2/STAT3, Not ERK1/2, Mediates Interleukin-6-induced Activation of Inducible Nitric-oxide Synthase and Decrease in Contractility of Adult Ventricular Myocytes.

X. Yu, R. H. Kennedy, and S. J. Liu (2003)
J. Biol. Chem. 278, 16304-16309
 |  Abstract »  |  Full Text »  |  PDF »

Inhaled Nitric Oxide Modifies Left Ventricular Diastolic Stress in the Presence of Vasoactive Agents in Heart Failure.

S. Natori, N. Hasebe, Y.-T. Jin, T. Matsusaka, A. Ido, H. Matsuhashi, T. Ihara, and K. Kikuchi (2003)
Am. J. Respir. Crit. Care Med. 167, 895-901
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines in Depression and Heart Failure.

J. Pasic, W. C. Levy, and M. D. Sullivan (2003)
Psychosom Med 65, 181-193
 |  Abstract »  |  Full Text »  |  PDF »

Chemokine-Cytokine Cross-talk. THE ELR+ CXC CHEMOKINE LIX (CXCL5) AMPLIFIES A PROINFLAMMATORY CYTOKINE RESPONSE VIA A PHOSPHATIDYLINOSITOL 3-KINASE-NF-kappa B PATHWAY.

B. Chandrasekar, P. C. Melby, H. M. Sarau, M. Raveendran, R. P. Perla, F. M. Marelli-Berg, N. O. Dulin, and I. S. Singh (2003)
J. Biol. Chem. 278, 4675-4686
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of tumor necrosis factor-alpha increases production of hydroxyl radical in murine myocardium.

Y. Machida, T. Kubota, N. Kawamura, H. Funakoshi, T. Ide, H. Utsumi, Y. Y. Li, A. M. Feldman, H. Tsutsui, H. Shimokawa, et al. (2003)
Am J Physiol Heart Circ Physiol 284, H449-H455
 |  Abstract »  |  Full Text »  |  PDF »

CHRONIC ETHANOL CONSUMPTION MODULATES MYOCARDIAL ISCHAEMIA-REPERFUSION INJURY IN MURINE AIDS.

Y. Chen, G. Davis-Gorman, R. R. Watson, and P. F. McDonagh (2003)
Alcohol Alcohol. 38, 18-24
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic inhibition of tumour necrosis factor {alpha} in patients with heart failure: cooling an inflamed heart.

P A Henriksen and D E Newby (2003)
Heart 89, 14-18
 |  Abstract »  |  Full Text »  |  PDF »

Quantification of proinflammatory cytokines in the urine of congestive heart failure patients. Its relationship with plasma levels.

R. Sirera, A. Salvador, I. Roldan, R. Talens, A. Gonzalez-Molina, and M. Rivera (2003)
Eur J Heart Fail 5, 27-31
 |  Abstract »  |  Full Text »  |  PDF »

Reduced Myocardial and Systemic L-Arginine Uptake in Heart Failure.

D. M. Kaye, M. M. Parnell, and B. A. Ahlers (2002)
Circ. Res. 91, 1198-1203
 |  Abstract »  |  Full Text »  |  PDF »

Heart failure as an inflammatory condition: potential role for androgens as immune modulators.

P. J. Pugh, R. D. Jones, T.H. Jones, and K. S. Channer (2002)
Eur J Heart Fail 4, 673-680
 |  Abstract »  |  Full Text »  |  PDF »

Pharmacotherapy of chronic heart failure: current status and future aspects.

M. Fuchs and H. Drexler (2002)
Eur. Heart J. Suppl. 4, I81-I87
 |  Abstract »  |  PDF »

Inflammatory Mediators and the Failing Heart: Past, Present, and the Foreseeable Future.

D. L. Mann (2002)
Circ. Res. 91, 988-998
 |  Abstract »  |  Full Text »  |  PDF »

Left ventricular pressure-volume relationship in a murine model of congestive heart failure due to acute viral myocarditis.

R. Nishio, S. Sasayama, and A. Matsumori (2002)
J. Am. Coll. Cardiol. 40, 1506-1514
 |  Abstract »  |  Full Text »  |  PDF »

Production of proinflammatory cytokines and myocardial dysfunction after arterial switch operation in neonates with transposition of the great arteries.

H. H. Hovels-Gurich, J. F. Vazquez-Jimenez, A. Silvestri, K. Schumacher, R. Minkenberg, J. Duchateau, B. J. Messmer, G. von Bernuth, and M.-C. Seghaye (2002)
J. Thorac. Cardiovasc. Surg. 124, 811-820
 |  Abstract »  |  Full Text »  |  PDF »

Tumor necrosis factor-{alpha} production in whole blood after cardiopulmonary bypass: Downregulation caused by circulating cytokine-inhibitory activities.

J. Borgermann, I. Friedrich, S. Flohe, J. Spillner, M. Majetschak, O. Kuss, A. Sablotzki, T. Feldt, J. C. Reidemeister, and F. U. Schade (2002)
J. Thorac. Cardiovasc. Surg. 124, 608-617
 |  Abstract »  |  Full Text »  |  PDF »

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice.

Y.-Y. Zhao, Y. Liu, R.-V. Stan, L. Fan, Y. Gu, N. Dalton, P.-H. Chu, K. Peterson, J. Ross Jr., and K. R. Chien (2002)
PNAS 99, 11375-11380
 |  Abstract »  |  Full Text »  |  PDF »

ICAM-1 and VCAM-1 mediate endotoxemic myocardial dysfunction independent of neutrophil accumulation.

C. D. Raeburn, C. M. Calkins, M. A. Zimmerman, Y. Song, L. Ao, A. Banerjee, A. H. Harken, and X. Meng (2002)
Am J Physiol Regulatory Integrative Comp Physiol 283, R477-R486
 |  Abstract »  |  Full Text »  |  PDF »

Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction.

C. D. Raeburn, C. A. Dinarello, M. A. Zimmerman, C. M. Calkins, B. J. Pomerantz, R. C. McIntyre Jr., A. H. Harken, and X. Meng (2002)
Am J Physiol Heart Circ Physiol 283, H650-H657
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of NOS II prevents cardiac dysfunction in myocardial infarction and congestive heart failure.

T. Saito, F. Hu, L. Tayara, L. Fahas, H. Shennib, and A. Giaid (2002)
Am J Physiol Heart Circ Physiol 283, H339-H345
 |  Abstract »  |  Full Text »  |  PDF »

Escherichia coli LPS-induced LV dysfunction: role of toll-like receptor-4 in the adult heart.

S. Nemoto, J. G. Vallejo, P. Knuefermann, A. Misra, G. Defreitas, B. A. Carabello, and D. L. Mann (2002)
Am J Physiol Heart Circ Physiol 282, H2316-H2323
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of inducible nitric oxide synthase in cardiac dysfunction with tumor necrosis factor-alpha.

H. Funakoshi, T. Kubota, Y. Machida, N. Kawamura, A. M. Feldman, H. Tsutsui, H. Shimokawa, and A. Takeshita (2002)
Am J Physiol Heart Circ Physiol 282, H2159-H2166
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of Inducible Nitric Oxide Synthase Improves {beta}-Adrenergic Inotropic Responsiveness but Not the Survival of Mice With Cytokine-Induced Cardiomyopathy.

H. Funakoshi, T. Kubota, N. Kawamura, Y. Machida, A. M. Feldman, H. Tsutsui, H. Shimokawa, and A. Takeshita (2002)
Circ. Res. 90, 959-965
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products