Science 10 July 1992: Vol. 257. no. 5067, pp. 238 - 241 DOI: 10.1126/science.1352912

Prev | Table of Contents | Next

Articles

CMV-Specific TCR-Transgenic T Cells for Immunotherapy.

A. Schub, I. G. Schuster, W. Hammerschmidt, and A. Moosmann (2009)
J. Immunol. 183, 6819-6830
 |  Abstract »  |  Full Text »  |  PDF »

The role of the human cytomegalovirus UL111A gene in down-regulating CD4+ T-cell recognition of latently infected cells: implications for virus elimination during latency.

A. K. L. Cheung, D. J. Gottlieb, B. Plachter, S. Pepperl-Klindworth, S. Avdic, A. L. Cunningham, A. Abendroth, and B. Slobedman (2009)
Blood 114, 4128-4137
 |  Abstract »  |  Full Text »  |  PDF »

Immune Evasion Proteins Enhance Cytomegalovirus Latency in the Lungs.

V. Bohm, C. K. Seckert, C. O. Simon, D. Thomas, A. Renzaho, D. Gendig, R. Holtappels, and M. J. Reddehase (2009)
J. Virol. 83, 10293-10298
 |  Abstract »  |  Full Text »  |  PDF »

The Efficacy of Antigen Processing Is Critical for Protection against Cytomegalovirus Disease in the Presence of Viral Immune Evasion Proteins.

R. Holtappels, D. Thomas, and M. J. Reddehase (2009)
J. Virol. 83, 9611-9615
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic Memory T Cells Require Costimulation for Effective Clearance of a Persistent Viral Infection.

L. Garidou, S. Heydari, P. Truong, D. G. Brooks, and D. B. McGavern (2009)
J. Virol. 83, 8905-8915
 |  Abstract »  |  Full Text »  |  PDF »

Epitope Specificity and Clonality of EBV-Specific CTLs Used to Treat Posttransplant Lymphoproliferative Disease.

K. A. McAulay, T. Haque, G. Urquhart, C. Bellamy, D. Guiretti, and D. H. Crawford (2009)
J. Immunol. 182, 3892-3901
 |  Abstract »  |  Full Text »  |  PDF »

Immunobiology of Human Cytomegalovirus: from Bench to Bedside.

T. Crough and R. Khanna (2009)
Clin. Microbiol. Rev. 22, 76-98
 |  Abstract »  |  Full Text »  |  PDF »

Clinical Trials Investigating Adoptive Cell Therapy Combined with Lymphodepletion for Patients with Advanced Cancer.

M. E. Dudley and S. A. Rosenberg (2009)
ASCO Educational Book 2009, 516-520
 |  Abstract »  |  Full Text »  |  PDF »

Graft-versus-leukemia effects of transplantation and donor lymphocytes.

H.-J. Kolb (2008)
Blood 112, 4371-4383
 |  Abstract »  |  Full Text »  |  PDF »

Prophylactic infusion of cytomegalovirus-specific cytotoxic T lymphocytes stimulated with Ad5f35pp65 gene-modified dendritic cells after allogeneic hemopoietic stem cell transplantation.

K. P. Micklethwaite, L. Clancy, U. Sandher, A. M. Hansen, E. Blyth, V. Antonenas, M. M. Sartor, K. F. Bradstock, and D. J. Gottlieb (2008)
Blood 112, 3974-3981
 |  Abstract »  |  Full Text »  |  PDF »

Long-term expansion of effector/memory V{delta}2- {gamma}{delta} T cells is a specific blood signature of CMV infection.

V. Pitard, D. Roumanes, X. Lafarge, L. Couzi, I. Garrigue, M.-E. Lafon, P. Merville, J.-F. Moreau, and J. Dechanet-Merville (2008)
Blood 112, 1317-1324
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Virus Carrier State to Evaluate Immunotherapeutic Regimens: Regulatory T Cells Modulate the Pathogenicity of Antiviral Memory Cells.

P. Truong and D. B. McGavern (2008)
J. Immunol. 181, 1161-1169
 |  Abstract »  |  Full Text »  |  PDF »

Subdominant CD8 T-Cell Epitopes Account for Protection against Cytomegalovirus Independent of Immunodomination.

R. Holtappels, C. O. Simon, M. W. Munks, D. Thomas, P. Deegen, B. Kuhnapfel, T. Daubner, S. F. Emde, J. Podlech, N. K. A. Grzimek, et al. (2008)
J. Virol. 82, 5781-5796
 |  Abstract »  |  Full Text »  |  PDF »

Immunomodulatory Properties of a Viral Homolog of Human Interleukin-10 Expressed by Human Cytomegalovirus during the Latent Phase of Infection.

C. Jenkins, W. Garcia, M. J. Godwin, J. V. Spencer, J. L. Stern, A. Abendroth, and B. Slobedman (2008)
J. Virol. 82, 3736-3750
 |  Abstract »  |  Full Text »  |  PDF »

The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation.

V. H. Nguyen, S. Shashidhar, D. S. Chang, L. Ho, N. Kambham, M. Bachmann, J. M. Brown, and R. S. Negrin (2008)
Blood 111, 945-953
 |  Abstract »  |  Full Text »  |  PDF »

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

A. Jorritsma, R. Gomez-Eerland, M. Dokter, W. van de Kasteele, Y. M. Zoet, I. I. N. Doxiadis, N. Rufer, P. Romero, R. A. Morgan, T. N. M. Schumacher, et al. (2007)
Blood 110, 3564-3572
 |  Abstract »  |  Full Text »  |  PDF »

Functional Human Antigen-Specific T Cells Produced In Vitro Using Retroviral T Cell Receptor Transfer into Hematopoietic Progenitors.

A. U. van Lent, M. Nagasawa, M. M. van Loenen, R. Schotte, T. N. M. Schumacher, M. H. M. Heemskerk, H. Spits, and N. Legrand (2007)
J. Immunol. 179, 4959-4968
 |  Abstract »  |  Full Text »  |  PDF »

4-1BB Is Superior to CD28 Costimulation for Generating CD8+ Cytotoxic Lymphocytes for Adoptive Immunotherapy.

H. Zhang, K. M. Snyder, M. M. Suhoski, M. V. Maus, V. Kapoor, C. H. June, and C. L. Mackall (2007)
J. Immunol. 179, 4910-4918
 |  Abstract »  |  Full Text »  |  PDF »

Gene-Engineered Varicella-Zoster Virus Reactive CD4+ Cytotoxic T Cells Exert Tumor-Specific Effector Function.

S. Landmeier, B. Altvater, S. Pscherer, B. R. Eing, J. Kuehn, C. M. Rooney, H. Juergens, and C. Rossig (2007)
Cancer Res. 67, 8335-8343
 |  Abstract »  |  Full Text »  |  PDF »

OX40 Costimulation Promotes Persistence of Cytomegalovirus-Specific CD8 T Cells: A CD4-Dependent Mechanism.

I. R. Humphreys, A. Loewendorf, C. de Trez, K. Schneider, C. A. Benedict, M. W. Munks, C. F. Ware, and M. Croft (2007)
J. Immunol. 179, 2195-2202
 |  Abstract »  |  Full Text »  |  PDF »

Protection from Lethal Infection by Adoptive Transfer of CD8 T Cells Genetically Engineered to Express Virus-Specific Innate Immune Receptor.

K. Iizuka, C. Nakajima, Y.-M. Iizuka, M. Takase, T. Kato, S. Noda, K. Tanaka, and O. Kanagawa (2007)
J. Immunol. 179, 1122-1128
 |  Abstract »  |  Full Text »  |  PDF »

Predictable {alpha}{beta} T-Cell Receptor Selection toward an HLA-B*3501-Restricted Human Cytomegalovirus Epitope.

R. M. Brennan, J. J. Miles, S. L. Silins, M. J. Bell, J. M. Burrows, and S. R. Burrows (2007)
J. Virol. 81, 7269-7273
 |  Abstract »  |  Full Text »  |  PDF »

Antitumor effects of HSV-TK engineered donor lymphocytes after allogeneic stem-cell transplantation.

F. Ciceri, C. Bonini, S. Marktel, E. Zappone, P. Servida, M. Bernardi, A. Pescarollo, A. Bondanza, J. Peccatori, S. Rossini, et al. (2007)
Blood 109, 4698-4707
 |  Abstract »  |  Full Text »  |  PDF »

Processing and MHC class I presentation of human cytomegalovirus pp65-derived peptides persist despite gpUS2-11-mediated immune evasion.

K. Besold, N. Frankenberg, S. Pepperl-Klindworth, J. Kuball, M. Theobald, G. Hahn, and B. Plachter (2007)
J. Gen. Virol. 88, 1429-1439
 |  Abstract »  |  Full Text »  |  PDF »

Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation.

J. P. Casazza, M. R. Betts, D. A. Price, M. L. Precopio, L. E. Ruff, J. M. Brenchley, B. J. Hill, M. Roederer, D. C. Douek, and R. A. Koup (2006)
J. Exp. Med. 203, 2865-2877
 |  Abstract »  |  Full Text »  |  PDF »

Viral Interference with B7-1 Costimulation: A New Role for Murine Cytomegalovirus Fc Receptor-1.

J. D. Mintern, E. J. Klemm, M. Wagner, M. E. Paquet, M. D. Napier, Y. M. Kim, U. H. Koszinowski, and H. L. Ploegh (2006)
J. Immunol. 177, 8422-8431
 |  Abstract »  |  Full Text »  |  PDF »

Generation of T Cell Help through a MHC Class I-Restricted TCR.

H. W. H. G. Kessels, K. Schepers, M. D. van den Boom, D. J. Topham, and T. N. M. Schumacher (2006)
J. Immunol. 177, 976-982
 |  Abstract »  |  Full Text »  |  PDF »

Secreted Proteins from Mycobacterium tuberculosis Gain Access to the Cytosolic MHC Class-I Antigen-Processing Pathway.

D. M. Lewinsohn, J. E. Grotzke, A. S. Heinzel, L. Zhu, P. J. Ovendale, M. Johnson, and M. R. Alderson (2006)
J. Immunol. 177, 437-442
 |  Abstract »  |  Full Text »  |  PDF »

Antibody-dependent cellular cytotoxicity (ADCC) is mediated by genetically modified antigen-specific human T lymphocytes.

B. Clemenceau, N. Congy-Jolivet, G. Gallot, R. Vivien, J. Gaschet, G. Thibault, and H. Vie (2006)
Blood 107, 4669-4677
 |  Abstract »  |  Full Text »  |  PDF »

Characterization and immunological analysis of the rhesus cytomegalovirus homologue (Rh112) of the human cytomegalovirus UL83 lower matrix phosphoprotein (pp65)..

Y. Yue, A. Kaur, S. S. Zhou, and P. A. Barry (2006)
J. Gen. Virol. 87, 777-787
 |  Abstract »  |  Full Text »  |  PDF »

Foxp3-Transduced Polyclonal Regulatory T Cells Protect against Chronic Renal Injury from Adriamycin.

Y. M. Wang, G. Y. Zhang, Y. Wang, M. Hu, H. Wu, D. Watson, S. Hori, I. E. Alexander, D. C.H. Harris, and S. I. Alexander (2006)
J. Am. Soc. Nephrol. 17, 697-706
 |  Abstract »  |  Full Text »  |  PDF »

Immunotherapeutic relief from persistent infections and amyloid disorders.

D. B. McGavern (2006)
Neurology 66, S59-S64
 |  Abstract »  |  Full Text »  |  PDF »

Human T Cells Armed with Her2/neu Bispecific Antibodies Divide, Are Cytotoxic, and Secrete Cytokines with Repeated Stimulation.

R. C. Grabert, L. P. Cousens, J. A. Smith, S. Olson, J. Gall, W. B. Young, P. A. Davol, and L. G. Lum (2006)
Clin. Cancer Res. 12, 569-576
 |  Abstract »  |  Full Text »  |  PDF »

Vaccine-Enhanced Donor Lymphocyte Infusion (veDLI).

J. D. Roback (2006)
Hematology 2006, 486-491
 |  Abstract »  |  Full Text »  |  PDF »

T-cell therapy for viral and fungal infections.

H. Einsele (2005)
Blood 106, 4023
 |  Full Text »  |  PDF »

CD1a-, b-, and c-Restricted TCRs Recognize Both Self and Foreign Antigens.

M. S. Vincent, X. Xiong, E. P. Grant, W. Peng, and M. B. Brenner (2005)
J. Immunol. 175, 6344-6351
 |  Abstract »  |  Full Text »  |  PDF »

Selection of T Cell Clones Expressing High-Affinity Public TCRs within Human Cytomegalovirus-Specific CD8 T Cell Responses.

L. Trautmann, M. Rimbert, K. Echasserieau, X. Saulquin, B. Neveu, J. Dechanet, V. Cerundolo, and M. Bonneville (2005)
J. Immunol. 175, 6123-6132
 |  Abstract »  |  Full Text »  |  PDF »

Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL.

N. R. Hegde, C. Dunn, D. M. Lewinsohn, M. A. Jarvis, J. A. Nelson, and D. C. Johnson (2005)
J. Exp. Med. 202, 1109-1119
 |  Abstract »  |  Full Text »  |  PDF »

Requirement for Neutralizing Antibodies to Control Bone Marrow Transplantation-Associated Persistent Viral Infection and to Reduce Immunopathology.

K. S. Lang, M. Recher, A. A. Navarini, S. Freigang, N. L. Harris, M. van den Broek, B. Odermatt, H. Hengartner, and R. M. Zinkernagel (2005)
J. Immunol. 175, 5524-5531
 |  Abstract »  |  Full Text »  |  PDF »

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers.

M. Cobbold, N. Khan, B. Pourgheysari, S. Tauro, D. McDonald, H. Osman, M. Assenmacher, L. Billingham, C. Steward, C. Crawley, et al. (2005)
J. Exp. Med. 202, 379-386
 |  Abstract »  |  Full Text »  |  PDF »

Repertoire, diversity, and differentiation of specific CD8 T cells are associated with immune protection against human cytomegalovirus disease.

K. Sacre, G. Carcelain, N. Cassoux, A.-M. Fillet, D. Costagliola, D. Vittecoq, D. Salmon, Z. Amoura, C. Katlama, and B. Autran (2005)
J. Exp. Med. 201, 1999-2010
 |  Abstract »  |  Full Text »  |  PDF »

Highly Protective In Vivo Function of Cytomegalovirus IE1 Epitope-Specific Memory CD8 T Cells Purified by T-Cell Receptor-Based Cell Sorting.

M.-F. Pahl-Seibert, M. Juelch, J. Podlech, D. Thomas, P. Deegen, M. J. Reddehase, and R. Holtappels (2005)
J. Virol. 79, 5400-5413
 |  Abstract »  |  Full Text »  |  PDF »

Molecular modification of idiotypes from B-cell lymphomas for expression in mature dendritic cells as a strategy to induce tumor-reactive CD4+ and CD8+ T-cell responses.

S. Muraro, A. Bondanza, M. Bellone, P. D. Greenberg, and C. Bonini (2005)
Blood 105, 3596-3604
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus (HIV)-Specific Gamma Interferon Secretion Directed against All Expressed HIV Genes: Relationship to Rate of CD4 Decline.

Y. Peretz, G. Alter, M.-P. Boisvert, G. Hatzakis, C. M. Tsoukas, and N. F. Bernard (2005)
J. Virol. 79, 4908-4917
 |  Abstract »  |  Full Text »  |  PDF »

HIV-1 Nef Disrupts Antigen Presentation Early in the Secretory Pathway.

M. R. Kasper, J. F. Roeth, M. Williams, T. M. Filzen, R. I. Fleis, and K. L. Collins (2005)
J. Biol. Chem. 280, 12840-12848
 |  Abstract »  |  Full Text »  |  PDF »

Generation of CMV-specific T lymphocytes using protein-spanning pools of pp65-derived overlapping pentadecapeptides for adoptive immunotherapy.

D. Trivedi, R. Y. Williams, R. J. O'Reilly, and G. Koehne (2005)
Blood 105, 2793-2801
 |  Abstract »  |  Full Text »  |  PDF »

The intensity of neutrophil infiltration controls the number of antigen-primed CD8 T cells recruited into cutaneous antigen challenge sites.

T. Engeman, A. V. Gorbachev, D. D. Kish, and R. L. Fairchild (2004)
J. Leukoc. Biol. 76, 941-949
 |  Abstract »  |  Full Text »  |  PDF »

Human CD62L- memory T cells are less responsive to alloantigen stimulation than CD62L+ naive T cells: potential for adoptive immunotherapy and allodepletion.

A. E. Foster, M. Marangolo, M. M. Sartor, S. I. Alexander, M. Hu, K. F. Bradstock, and D. J. Gottlieb (2004)
Blood 104, 2403-2409
 |  Abstract »  |  Full Text »  |  PDF »

Human Cytomegalovirus-Encoded Interleukin-10 Homolog Inhibits Maturation of Dendritic Cells and Alters Their Functionality.

W. L. W. Chang, N. Baumgarth, D. Yu, and P. A. Barry (2004)
J. Virol. 78, 8720-8731
 |  Abstract »  |  Full Text »  |  PDF »

Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection.

T. J. Manley, L. Luy, T. Jones, M. Boeckh, H. Mutimer, and S. R. Riddell (2004)
Blood 104, 1075-1082
 |  Abstract »  |  Full Text »  |  PDF »

Attenuated poxviruses generate clinically relevant frequencies of CMV-specific T cells.

Z. Wang, C. La Rosa, S. Mekhoubad, S. F. Lacey, M. C. Villacres, S. Markel, J. Longmate, J. D. I. Ellenhorn, R. F. Siliciano, C. Buck, et al. (2004)
Blood 104, 847-856
 |  Abstract »  |  Full Text »  |  PDF »

Identification of new Th peptides from the cytomegalovirus protein pp65 to design a peptide library for generation of CD4 T cell lines for cellular immunoreconstitution.

G. Li Pira, L. Bottone, F. Ivaldi, R. Pelizzoli, F. Del Galdo, L. Lozzi, L. Bracci, A. Loregian, G. Palu, R. De Palma, et al. (2004)
Int. Immunol. 16, 635-642
 |  Abstract »  |  Full Text »  |  PDF »

Rapid generation of combined CMV-specific CD4+ and CD8+ T-cell lines for adoptive transfer into recipients of allogeneic stem cell transplants.

G. Rauser, H. Einsele, C. Sinzger, D. Wernet, G. Kuntz, M. Assenmacher, J. D. M. Campbell, and M. S. Topp (2004)
Blood 103, 3565-3572
 |  Abstract »  |  Full Text »  |  PDF »

A Cytomegalovirus Inhibitor of Gamma Interferon Signaling Controls Immunoproteasome Induction.

S. Khan, A. Zimmermann, M. Basler, M. Groettrup, and H. Hengel (2004)
J. Virol. 78, 1831-1842
 |  Abstract »  |  Full Text »  |  PDF »

Human Cytomegalovirus Proteins pp65 and Immediate Early Protein 1 Are Common Targets for CD8+ T Cell Responses in Children with Congenital or Postnatal Human Cytomegalovirus Infection.

L. Gibson, G. Piccinini, D. Lilleri, M. G. Revello, Z. Wang, S. Markel, D. J. Diamond, and K. Luzuriaga (2004)
J. Immunol. 172, 2256-2264
 |  Abstract »  |  Full Text »  |  PDF »

Identification of novel CTL epitopes of CMV-pp65 presented by a variety of HLA alleles.

E. Kondo, Y. Akatsuka, K. Kuzushima, K. Tsujimura, S. Asakura, K. Tajima, Y. Kagami, Y. Kodera, M. Tanimoto, Y. Morishima, et al. (2004)
Blood 103, 630-638
 |  Abstract »  |  Full Text »  |  PDF »

Melanoma-Reactive Class I-Restricted Cytotoxic T Cell Clones Are Stimulated by Dendritic Cells Loaded with Synthetic Peptides, but Fail to Respond to Dendritic Cells Pulsed with Melanoma-Derived Heat Shock Proteins In Vitro.

K. Fleischer, B. Schmidt, W. Kastenmuller, D. H. Busch, I. Drexler, G. Sutter, M. Heike, C. Peschel, and H. Bernhard (2004)
J. Immunol. 172, 162-169
 |  Abstract »  |  Full Text »  |  PDF »

Antibody responses to rhesus cytomegalovirus glycoprotein B in naturally infected rhesus macaques.

Y. Yue, S. S. Zhou, and P. A. Barry (2003)
J. Gen. Virol. 84, 3371-3379
 |  Abstract »  |  Full Text »  |  PDF »

Dendritic Cells Pulsed with Polyomavirus BK Antigen Induce Ex Vivo Polyoma BK Virus-Specific Cytotoxic T-Cell Lines in Seropositive Healthy Individuals and Renal Transplant Recipients.

P. Comoli, S. Basso, A. Azzi, A. Moretta, R. De Santis, F. Del Galdo, R. De Palma, U. Valente, A. Nocera, F. Perfumo, et al. (2003)
J. Am. Soc. Nephrol. 14, 3197-3204
 |  Abstract »  |  Full Text »  |  PDF »

Mycobacterium tuberculosis-specific CD8+ T Cells Preferentially Recognize Heavily Infected Cells.

D. A. Lewinsohn, A. S. Heinzel, J. M. Gardner, L. Zhu, M. R. Alderson, and D. M. Lewinsohn (2003)
Am. J. Respir. Crit. Care Med. 168, 1346-1352
 |  Abstract »  |  Full Text »  |  PDF »

Immunodominance of an Antiviral Cytotoxic T Cell Response Is Shaped by the Kinetics of Viral Protein Expression.

H. C. Probst, K. Tschannen, A. Gallimore, M. Martinic, M. Basler, T. Dumrese, E. Jones, and M. F. van den Broek (2003)
J. Immunol. 171, 5415-5422
 |  Abstract »  |  Full Text »  |  PDF »

Prevention of Cytomegalovirus Disease in Recipients of Allogeneic Stem Cell Transplants.

E. Meijer, G. J. Boland, and L. F. Verdonck (2003)
Clin. Microbiol. Rev. 16, 647-657
 |  Abstract »  |  Full Text »  |  PDF »

Rapid expansion of cytomegalovirus-specific cytotoxic T lymphocytes by artificial antigen-presenting cells expressing a single HLA allele.

G. A. Papanicolaou, J.-B. Latouche, C. Tan, J. Dupont, J. Stiles, E. G. Pamer, and M. Sadelain (2003)
Blood 102, 2498-2505
 |  Abstract »  |  Full Text »  |  PDF »

Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation.

C. Arber, A. BitMansour, T. E. Sparer, J. P. Higgins, E. S. Mocarski, I. L. Weissman, J. A. Shizuru, and J. M. Y. Brown (2003)
Blood 102, 421-428
 |  Abstract »  |  Full Text »  |  PDF »

Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence.

S. Cavalieri, S. Cazzaniga, M. Geuna, Z. Magnani, C. Bordignon, L. Naldini, and C. Bonini (2003)
Blood 102, 497-505
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Reactivity of HLA-B*1801-Restricted T-Lymphocyte Clones with Target Cells Expressing Variants of the Human Cytomegalovirus 72kDa-IE1 Protein.

V. Prod'homme, C. Retiere, R. Valtcheva, M. Bonneville, and M.-M. Hallet (2003)
J. Virol. 77, 7139-7142
 |  Abstract »  |  Full Text »  |  PDF »

Memory Inflation: Continuous Accumulation of Antiviral CD8+ T Cells Over Time.

U. Karrer, S. Sierro, M. Wagner, A. Oxenius, H. Hengel, U. H. Koszinowski, R. E. Phillips, and P. Klenerman (2003)
J. Immunol. 170, 2022-2029
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of HLA-A*0201-Restricted T Cell Responses by Natural Polymorphism in the IE1315-324 Epitope of Human Cytomegalovirus.

V. Prod'homme, C. Retiere, B.-M. Imbert-Marcille, M. Bonneville, and M.-M. Hallet (2003)
J. Immunol. 170, 2030-2036
 |  Abstract »  |  Full Text »  |  PDF »

Survival and Tumor Localization of Adoptively Transferred Melan-A-Specific T Cells in Melanoma Patients.

N. Meidenbauer, J. Marienhagen, M. Laumer, S. Vogl, J. Heymann, R. Andreesen, and A. Mackensen (2003)
J. Immunol. 170, 2161-2169
 |  Abstract »  |  Full Text »  |  PDF »

Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation.

S. Marktel, Z. Magnani, F. Ciceri, S. Cazzaniga, S. R. Riddell, C. Traversari, C. Bordignon, and C. Bonini (2003)
Blood 101, 1290-1298
 |  Abstract »  |  Full Text »  |  PDF »

Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines.

I. Drexler, C. Staib, W. Kastenmuller, S. Stevanovic', B. Schmidt, F. A. Lemonnier, H.-G. Rammensee, D. H. Busch, H. Bernhard, V. Erfle, et al. (2003)
PNAS 100, 217-222
 |  Abstract »  |  Full Text »  |  PDF »

T cells take aim at cancer.

D. Pardoll (2002)
PNAS 99, 15840-15842
 |  Full Text »  |  PDF »

HLA-E-dependent Presentation of Mtb-derived Antigen to Human CD8+ T Cells.

A. S. Heinzel, J. E. Grotzke, R. A. Lines, D. A. Lewinsohn, A. L. McNabb, D. N. Streblow, V. M. Braud, H. J. Grieser, J. T. Belisle, and D. M. Lewinsohn (2002)
J. Exp. Med. 196, 1473-1481
 |  Abstract »  |  Full Text »  |  PDF »

Cytomegalovirus reactivation following allogeneic stem cell transplantation is associated with the presence of dysfunctional antigen-specific CD8+ T cells.

E. Ozdemir, L. S. St. John, G. Gillespie, S. Rowland-Jones, R. E. Champlin, J. J. Molldrem, and K. V. Komanduri (2002)
Blood 100, 3690-3697
 |  Abstract »  |  Full Text »  |  PDF »

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes.

M. E. Dudley, J. R. Wunderlich, P. F. Robbins, J. C. Yang, P. Hwu, D. J. Schwartzentruber, S. L. Topalian, R. Sherry, N. P. Restifo, A. M. Hubicki, et al. (2002)
Science 298, 850-854
 |  Abstract »  |  Full Text »  |  PDF »

Latent cytomegalovirus down-regulates major histocompatibility complex class II expression on myeloid progenitors.

B. Slobedman, E. S. Mocarski, A. M. Arvin, E. D. Mellins, and A. Abendroth (2002)
Blood 100, 2867-2873
 |  Abstract »  |  Full Text »  |  PDF »

Human Dendritic Cells Presenting Adenovirally Expressed Antigen Elicit Mycobacterium tuberculosis-Specific CD8+ T Cells.

D. A. Lewinsohn, R. A. Lines, and D. M. Lewinsohn (2002)
Am. J. Respir. Crit. Care Med. 166, 843-848
 |  Abstract »  |  Full Text »

NK Cell Activity During Human Cytomegalovirus Infection Is Dominated by US2-11-Mediated HLA Class I Down-Regulation.

C. S. Falk, M. Mach, D. J. Schendel, E. H. Weiss, I. Hilgert, and G. Hahn (2002)
J. Immunol. 169, 3257-3266
 |  Abstract »  |  Full Text »  |  PDF »

Efficient Generation of Antigen-Specific Cytotoxic T Cells Using Retrovirally Transduced CD40-Activated B Cells.

E. Kondo, M. S. Topp, H.-P. Kiem, Y. Obata, Y. Morishima, K. Kuzushima, M. Tanimoto, M. Harada, T. Takahashi, and Y. Akatsuka (2002)
J. Immunol. 169, 2164-2171
 |  Abstract »  |  Full Text »  |  PDF »

B cells immortalized by a mini-Epstein-Barr virus encoding a foreign antigen efficiently reactivate specific cytotoxic T cells.

A. Moosmann, N. Khan, M. Cobbold, C. Zentz, H.-J. Delecluse, G. Hollweck, A. D. Hislop, N. W. Blake, D. Croom-Carter, B. Wollenberg, et al. (2002)
Blood 100, 1755-1764
 |  Abstract »  |  Full Text »  |  PDF »

Processing and Presentation of Murine Cytomegalovirus pORFm164-Derived Peptide in Fibroblasts in the Face of All Viral Immunosubversive Early Gene Functions.

R. Holtappels, N. K. A. Grzimek, C. O. Simon, D. Thomas, D. Dreis, and M. J. Reddehase (2002)
J. Virol. 76, 6044-6053
 |  Abstract »  |  Full Text »  |  PDF »

Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy.

H. Einsele, E. Roosnek, N. Rufer, C. Sinzger, S. Riegler, J. Loffler, U. Grigoleit, A. Moris, H.-G. Rammensee, L. Kanz, et al. (2002)
Blood 99, 3916-3922
 |  Abstract »  |  Full Text »  |  PDF »

Direct Costimulation of Tumor-reactive CTL by Helper T Cells Potentiate Their Proliferation, Survival, and Effector Function.

R. L. Giuntoli II, J. Lu, H. Kobayashi, R. Kennedy, and E. Celis (2002)
Clin. Cancer Res. 8, 922-931
 |  Abstract »  |  Full Text »  |  PDF »

Identification of BING-4 Cancer Antigen Translated From an Alternative Open Reading Frame of a Gene in the Extended MHC Class II Region Using Lymphocytes From a Patient With a Durable Complete Regression Following Immunotherapy.

S. A. Rosenberg, P. Tong-On, Y. Li, J. P. Riley, M. El-Gamil, M. R. Parkhurst, and P. F. Robbins (2002)
J. Immunol. 168, 2402-2407
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of human cytomegalovirus peptide-specific CD8+ T-cell repertoire diversity following in vitro restimulation by antigen-pulsed dendritic cells.

K. Peggs, S. Verfuerth, A. Pizzey, J. Ainsworth, P. Moss, and S. Mackinnon (2002)
Blood 99, 213-223
 |  Abstract »  |  Full Text »  |  PDF »

Efficient identification of HLA-A*2402-restricted cytomegalovirus-specific CD8+ T-cell epitopes by a computer algorithm and an enzyme-linked immunospot assay.

K. Kuzushima, N. Hayashi, H. Kimura, and T. Tsurumi (2001)
Blood 98, 1872-1881
 |  Abstract »  |  Full Text »  |  PDF »

The Generation of Both T Killer and Th Cell Clones Specific for the Tumor-Associated Antigen HER2 Using Retrovirally Transduced Dendritic Cells.

C. Meyer zum Buschenfelde, J. Metzger, C. Hermann, N. Nicklisch, C. Peschel, and H. Bernhard (2001)
J. Immunol. 167, 1712-1719
 |  Abstract »  |  Full Text »  |  PDF »

Experimental Preemptive Immunotherapy of Murine Cytomegalovirus Disease with CD8 T-Cell Lines Specific for ppM83 and pM84, the Two Homologs of Human Cytomegalovirus Tegument Protein ppUL83 (pp65).

R. Holtappels, J. Podlech, N. K. A. Grzimek, D. Thomas, M.-F. Pahl-Seibert, and M. J. Reddehase (2001)
J. Virol. 75, 6584-6600
 |  Abstract »  |  Full Text »

Targeting Antigen in Mature Dendritic Cells for Simultaneous Stimulation of CD4+ and CD8+ T Cells.

C. Bonini, S. P. Lee, S. R. Riddell, and P. D. Greenberg (2001)
J. Immunol. 166, 5250-5257
 |  Abstract »  |  Full Text »  |  PDF »

Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation.

K. Cwynarski, J. Ainsworth, M. Cobbold, S. Wagner, P. Mahendra, J. Apperley, J. Goldman, C. Craddock, and P. A. H. Moss (2001)
Blood 97, 1232-1240
 |  Abstract »  |  Full Text »  |  PDF »

A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease.

D. C. Thomis, S. Marktel, C. Bonini, C. Traversari, M. Gilman, C. Bordignon, and T. Clackson (2001)
Blood 97, 1249-1257
 |  Abstract »  |  Full Text »  |  PDF »

Induction of cytomegalovirus (CMV)-specific T-cell responses using dendritic cells pulsed with CMV antigen: a novel culture system free of live CMV virions.

K. Peggs, S. Verfuerth, and S. Mackinnon (2001)
Blood 97, 994-1000
 |  Abstract »  |  Full Text »  |  PDF »

High-Avidity CTL Exploit Two Complementary Mechanisms to Provide Better Protection Against Viral Infection Than Low-Avidity CTL.

M. A. Derby, M. A. Alexander-Miller, R. Tse, and J. A. Berzofsky (2001)
J. Immunol. 166, 1690-1697
 |  Abstract »  |  Full Text »  |  PDF »

Substantial Differences in Specificity of HIV-Specific Cytotoxic T Cells in Acute and Chronic HIV Infection.

P. J.R. Goulder, M. A. Altfeld, E. S. Rosenberg, T. Nguyen, Y. Tang, R. L. Eldridge, M. M. Addo, S. He, J. S. Muckerjee, M. N. Phillips, et al. (2001)
J. Exp. Med. 193, 181-194
 |  Abstract »  |  Full Text »  |  PDF »

Classically Restricted Human CD8+ T Lymphocytes Derived from Mycobacterium tuberculosis-Infected Cells: Definition of Antigenic Specificity.

D. M. Lewinsohn, L. Zhu, V. J. Madison, D. C. Dillon, S. P. Fling, S. G. Reed, K. H. Grabstein, and M. R. Alderson (2001)
J. Immunol. 166, 439-446
 |  Abstract »  |  Full Text »  |  PDF »

Enrichment of Immediate-Early 1 (m123/pp89) Peptide-Specific CD8 T Cells in a Pulmonary CD62Llo Memory-Effector Cell Pool during Latent Murine Cytomegalovirus Infection of the Lungs.

R. Holtappels, M.-F. Pahl-Seibert, D. Thomas, and M. J. Reddehase (2000)
J. Virol. 74, 11495-11503
 |  Abstract »  |  Full Text »

Reversal of CD8+ T Cell Ignorance and Induction of Anti-Tumor Immunity by Peptide-Pulsed APC.

N. Dalyot-Herman, O. F. Bathe, and T. R. Malek (2000)
J. Immunol. 165, 6731-6737
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products