Science 3 July 1992: Vol. 257. no. 5066, pp. 88 - 91 DOI: 10.1126/science.1621100

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Articles

NF-{kappa}B as a Critical Link Between Inflammation and Cancer.

M. Karin (2009)
Cold Spring Harb Perspect Biol 1, a000141
 |  Abstract »  |  Full Text »  |  PDF »

Perspective on post-menopausal osteoporosis: establishing an interdisciplinary understanding of the sequence of events from the molecular level to whole bone fractures.

L. M. McNamara (2009)
J R Soc Interface
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Osteoimmunology: Interactions of the Bone and Immune System.

J. Lorenzo, M. Horowitz, and Y. Choi (2008)
Endocr. Rev. 29, 403-440
 |  Abstract »  |  Full Text »  |  PDF »

Circulating Levels of Inflammatory Markers Predict Change in Bone Mineral Density and Resorption in Older Adults: A Longitudinal Study.

C. Ding, V. Parameswaran, R. Udayan, J. Burgess, and G. Jones (2008)
J. Clin. Endocrinol. Metab. 93, 1952-1958
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Polymorphisms in the interleukin-6 receptor gene are associated with bone mineral density and body mass index in Spanish postmenopausal women.

M Bustamante, X Nogues, L Mellibovsky, L Agueda, S Jurado, E Caceres, J Blanch, R Carreras, A Diez-Perez, D Grinberg, et al. (2007)
Eur. J. Endocrinol. 157, 677-684
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Stimulation of Cells Derived from Nifedipine-induced Gingival Overgrowth with Porphyromonas gingivalis, Lipopolysaccharide, and Interleukin-1{beta}.

H.-K. Lu, H.-P. Chou, C.-L. Li, M.-Y. Wang, and L.-F. Wang (2007)
Journal of Dental Research 86, 1100-1104
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p38 MAPK Signaling in Oral-related Diseases.

C.S. Patil and K.L. Kirkwood (2007)
Journal of Dental Research 86, 812-825
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The Complex Role of Estrogens in Inflammation.

R. H. Straub (2007)
Endocr. Rev. 28, 521-574
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Assessing Osteolysis with Use of High-Throughput Protein Chips.

A. S. Shanbhag, A. M. Kaufman, K. Hayata, and H. E. Rubash (2007)
J. Bone Joint Surg. Am. 89, 1081-1089
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A role for cell sex in stem cell-mediated skeletal muscle regeneration: female cells have higher muscle regeneration efficiency.

B. M. Deasy, A. Lu, J. C. Tebbets, J. M. Feduska, R. C. Schugar, J. B. Pollett, B. Sun, K. L. Urish, B. M. Gharaibeh, B. Cao, et al. (2007)
J. Cell Biol. 177, 73-86
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Effects of calcium supplementation on bone loss and fractures in congestive heart failure.

R. J A Frost, C. Sonne, U. Wehr, and H.-U. Stempfle (2007)
Eur. J. Endocrinol. 156, 309-314
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Estrogen receptor signaling protects against immune suppression by UV radiation exposure.

S. Widyarini, D. Domanski, N. Painter, and V. E. Reeve (2006)
PNAS 103, 12837-12842
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Bone Remodeling in Post-menopausal Osteoporosis.

U.H. Lerner (2006)
Journal of Dental Research 85, 584-595
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Tissue-specific expression of estrogen receptors and their role in the regulation of neutrophil infiltration in various organs following trauma-hemorrhage.

H.-P. Yu, T. Shimizu, Y.-C. Hsieh, T. Suzuki, M. A. Choudhry, M. G. Schwacha, and I. H. Chaudry (2006)
J. Leukoc. Biol. 79, 963-970
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Plasma Membrane-associated Sialidase Is Up-regulated in Renal Cell Carcinoma and Promotes Interleukin-6-induced Apoptosis Suppression and Cell Motility.

S. Ueno, S. Saito, T. Wada, K. Yamaguchi, M. Satoh, Y. Arai, and T. Miyagi (2006)
J. Biol. Chem. 281, 7756-7764
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Effects of Selective Testosterone and Estradiol Withdrawal on Skeletal Sensitivity to Parathyroid Hormone in Men.

H. Lee, J. S. Finkelstein, M. Miller, S. J. Comeaux, R. I. Cohen, and B. Z. Leder (2006)
J. Clin. Endocrinol. Metab. 91, 1069-1075
 |  Abstract »  |  Full Text »  |  PDF »

Can Systemic Diseases Co-induce (Not Just Exacerbate) Periodontitis? A Hypothetical "Two-hit" Model.

L.M. Golub, J.B. Payne, R.A. Reinhardt, and G. Nieman (2006)
Journal of Dental Research 85, 102-105
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Different Molecular Mechanisms Underlie Ethanol-Induced Bone Loss in Cycling and Pregnant Rats.

K. Shankar, M. Hidestrand, R. Haley, R. A. Skinner, W. Hogue, C.-H. Jo, P. Simpson, C. K. Lumpkin Jr., J. Aronson, T. M. Badger, et al. (2006)
Endocrinology 147, 166-178
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The pathophysiology of the growth plate in juvenile idiopathic arthritis.

V. E. MacRae, C. Farquharson, and S. F. Ahmed (2006)
Rheumatology 45, 11-19
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Combined Oral Contraceptives in Women with Systemic Lupus Erythematosus.

M. Petri, M. Y. Kim, K. C. Kalunian, J. Grossman, B. H. Hahn, L. R. Sammaritano, M. Lockshin, J. T. Merrill, H. M. Belmont, A. D. Askanase, et al. (2005)
N. Engl. J. Med. 353, 2550-2558
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IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice.

C. A. O'Brien, R. L. Jilka, Q. Fu, S. Stewart, R. S. Weinstein, and S. C. Manolagas (2005)
Am J Physiol Endocrinol Metab 289, E784-E793
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Low-Grade Inflammation and Estimates of Insulin Resistance during the Menstrual Cycle in Lean and Overweight Women.

C. A. Blum, B. Muller, P. Huber, M. Kraenzlin, C. Schindler, C. De Geyter, U. Keller, and J. J. Puder (2005)
J. Clin. Endocrinol. Metab. 90, 3230-3235
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Nuclear Factor-{kappa}B-Dependent Mechanisms in Breast Cancer Cells Regulate Tumor Burden and Osteolysis in Bone.

A. H. Gordon, R. J. O'Keefe, E. M. Schwarz, R. N. Rosier, and J. E. Puzas (2005)
Cancer Res. 65, 3209-3217
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Nongenotropic, Anti-Apoptotic Signaling of 1{alpha},25(OH)2-Vitamin D3 and Analogs through the Ligand Binding Domain of the Vitamin D Receptor in Osteoblasts and Osteocytes: MEDIATION BY Src, PHOSPHATIDYLINOSITOL 3-, AND JNK KINASES.

A. M. Vertino, C. M. Bula, J.-R. Chen, M. Almeida, L. Han, T. Bellido, S. Kousteni, A. W. Norman, and S. C. Manolagas (2005)
J. Biol. Chem. 280, 14130-14137
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Regulatory effects of estrogen on acute lung inflammation in mice.

C. L. Speyer, N. J. Rancilio, S. D. McClintock, J. D. Crawford, H. Gao, J. V. Sarma, and P. A. Ward (2005)
Am J Physiol Cell Physiol 288, C881-C890
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Cross-Talk between the Interleukin-6 and Prostaglandin E2 Signaling Systems Results in Enhancement of Osteoclastogenesis through Effects on the Osteoprotegerin/Receptor Activator of Nuclear Factor-{kappa}B (RANK) Ligand/RANK System.

X.-H. Liu, A. Kirschenbaum, S. Yao, and A. C. Levine (2005)
Endocrinology 146, 1991-1998
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Transient Versus Sustained Phosphorylation and Nuclear Accumulation of ERKs Underlie Anti-Versus Pro-apoptotic Effects of Estrogens.

J.-R. Chen, L. I. Plotkin, J. I. Aguirre, L. Han, R. L. Jilka, S. Kousteni, T. Bellido, and S. C. Manolagas (2005)
J. Biol. Chem. 280, 4632-4638
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Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor-{alpha}-deficient male and female mice.

V. Parikka, Z. Peng, T. Hentunen, J. Risteli, T. Elo, H K. Vaananen, and P. Harkonen (2005)
Eur. J. Endocrinol. 152, 301-314
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The Molecular Pharmacology of Estrogen Receptor Modulators: Implications for the Treatment of Breast Cancer.

D. P. McDonnell (2005)
Clin. Cancer Res. 11, 871s-877s
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Osteoprotegerin and osteopontin serum values in postmenopausal advanced breast cancer patients treated with anastrozole.

A Martinetti, E Bajetta, L Ferrari, N Zilembo, E Seregni, M Del Vecchio, R Longarini, I La Torre, L Toffolatti, D Paleari, et al. (2004)
Endocr. Relat. Cancer 11, 771-779
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Raloxifene Modulates Interleukin-6 and Tumor Necrosis Factor-{alpha} Synthesis in Vivo: Results from a Pilot Clinical Study.

W. Gianni, A. Ricci, P. Gazzaniga, M. Brama, M. Pietropaolo, S. Votano, F. Patane, A. M. Agliano, G. Spera, V. Marigliano, et al. (2004)
J. Clin. Endocrinol. Metab. 89, 6097-6099
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Menstrual and Reproductive Factors and Risk of Non-Hodgkin's Lymphoma among Connecticut Women.

Y. Zhang, T. R. Holford, B. Leaderer, P. Boyle, S. H. Zahm, B. Zhang, K. Zou, L. M. Morton, P. H. Owens, S. Flynn, et al. (2004)
Am. J. Epidemiol. 160, 766-773
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Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjogren's syndrome.

G.-J. Shim, M. Warner, H.-J. Kim, S. Andersson, L. Liu, J. Ekman, O. Imamov, M. E. Jones, E. R. Simpson, and J.-A. Gustafsson (2004)
PNAS 101, 12628-12633
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Estrogen Deficiency Accelerates Murine Autoimmune Arthritis Associated with Receptor Activator of Nuclear Factor-{kappa}B Ligand-Mediated Osteoclastogenesis.

T. Yoneda, N. Ishimaru, R. Arakaki, M. Kobayashi, T. Izawa, K. Moriyama, and Y. Hayashi (2004)
Endocrinology 145, 2384-2391
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Nitric Oxide Donor Increases Osteoprotegerin Production and Osteoclastogenesis Inhibitory Activity in Bone Marrow Stromal Cells from Ovariectomized Rats.

F.-S. Wang, C.-J. Wang, Y.-J. Chen, Y.-T. Huang, H.-C. Huang, P.-R. Chang, Y.-C. Sun, and K. D. Yang (2004)
Endocrinology 145, 2148-2156
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The Skeletal Effects of Glucocorticoid Excess Override Those of Orchidectomy in Mice.

R. S. Weinstein, D. Jia, C. C. Powers, S. A. Stewart, R. L. Jilka, A. M. Parfitt, and S. C. Manolagas (2004)
Endocrinology 145, 1980-1987
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Metacarpal Cortical Area and Risk of Coronary Heart Disease: The Framingham Study.

E. J. Samelson, D. P. Kiel, K. E. Broe, Y. Zhang, L. A. Cupples, M. T. Hannan, P. W. F. Wilson, D. Levy, S. A. Williams, and V. Vaccarino (2004)
Am. J. Epidemiol. 159, 589-595
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Beneficial effects of estrogen treatment in the HLA-B27 transgenic rat model of inflammatory bowel disease.

D. C. Harnish, L. M. Albert, Y. Leathurby, A. M. Eckert, A. Ciarletta, M. Kasaian, and J. C. Keith Jr. (2004)
Am J Physiol Gastrointest Liver Physiol 286, G118-G125
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Dexamethasone Enhances Osteoclast Formation Synergistically with Transforming Growth Factor-{beta} by Stimulating the Priming of Osteoclast Progenitors for Differentiation into Osteoclasts.

A. Takuma, T. Kaneda, T. Sato, S. Ninomiya, M. Kumegawa, and Y. Hakeda (2003)
J. Biol. Chem. 278, 44667-44674
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Bone Turnover in Prolonged Critical Illness: Effect of Vitamin D.

G. Van den Berghe, D. Van Roosbroeck, P. Vanhove, P. J. Wouters, L. De Pourcq, and R. Bouillon (2003)
J. Clin. Endocrinol. Metab. 88, 4623-4632
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Role of Monocytes in Atherogenesis.

B. OSTERUD and E. BJORKLID (2003)
Physiol Rev 83, 1069-1112
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Disruption of the estrogen receptor {beta} gene in mice causes myeloproliferative disease resembling chronic myeloid leukemia with lymphoid blast crisis.

G.-J. Shim, L. Wang, S. Andersson, N. Nagy, L. L. Kis, Q. Zhang, S. Makela, M. Warner, and J.-A. Gustafsson (2003)
PNAS 100, 6694-6699
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of Growth Factor/Cytokine Synthesis and Signaling by 1{alpha},25-Dihydroxyvitamin D3: Implications in Cell Growth and Differentiation.

A. Gurlek, M. R. Pittelkow, and R. Kumar (2002)
Endocr. Rev. 23, 763-786
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Characterization of an Antagonist Interleukin-6 Dimer by Stable Isotope Labeling, Cross-linking, and Mass Spectrometry.

T. Taverner, N. E. Hall, R. A. J. O'Hair, and R. J. Simpson (2002)
J. Biol. Chem. 277, 46487-46492
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Transcriptional Synergism on the pS2 Gene Promoter between a p160 Coactivator and Estrogen Receptor-{alpha} Depends on the Coactivator Subtype, the Type of Estrogen Response Element, and the Promoter Context.

T. Barkhem, L.-A. Haldosen, J.-A. Gustafsson, and S. Nilsson (2002)
Mol. Endocrinol. 16, 2571-2581
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IL-6, Leukemia Inhibitory Factor, and Oncostatin M Stimulate Bone Resorption and Regulate the Expression of Receptor Activator of NF-{kappa}B Ligand, Osteoprotegerin, and Receptor Activator of NF-{kappa}B in Mouse Calvariae.

P. Palmqvist, E. Persson, H. H. Conaway, and U. H. Lerner (2002)
J. Immunol. 169, 3353-3362
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Regulation of Receptor Activator of NF-kappa B Ligand-induced Osteoclastogenesis by Endogenous Interferon-beta (INF-beta ) and Suppressors of Cytokine Signaling (SOCS). THE POSSIBLE COUNTERACTING ROLE OF SOCSs IN IFN-beta -INHIBITED OSTEOCLAST FORMATION.

T. Hayashi, T. Kaneda, Y. Toyama, M. Kumegawa, and Y. Hakeda (2002)
J. Biol. Chem. 277, 27880-27886
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Receptor {alpha} Inhibits IL-1{beta} Induction of Gene Expression in the Mouse Liver.

M. J. Evans, K. Lai, L. J. Shaw, D. C. Harnish, and C. C. Chadwick (2002)
Endocrinology 143, 2559-2570
 |  Abstract »  |  Full Text »  |  PDF »

Biological activity of anastrozole in postmenopausal patients with advanced breast cancer: effects on estrogens and bone metabolism.

E. Bajetta, A. Martinetti, N. Zilembo, P. Pozzi, I. La Torre, L. Ferrari, E. Seregni, R. Longarini, G. Salvucci, and E. Bombardieri (2002)
Ann. Onc. 13, 1059-1066
 |  Abstract »  |  Full Text »  |  PDF »

Evidence that the IL-6/IL-6 Soluble Receptor Cytokine System Plays a Role in the Increased Skeletal Sensitivity to PTH in Estrogen-Deficient Women.

U. S. Masiukiewicz, M. Mitnick, B. I. Gulanski, and K. L. Insogna (2002)
J. Clin. Endocrinol. Metab. 87, 2892-2898
 |  Abstract »  |  Full Text »  |  PDF »

alpha 2-HS Glycoprotein/Fetuin, a Transforming Growth Factor-beta /Bone Morphogenetic Protein Antagonist, Regulates Postnatal Bone Growth and Remodeling.

M. Szweras, D. Liu, E. A. Partridge, J. Pawling, B. Sukhu, C. Clokie, W. Jahnen-Dechent, H. C. Tenenbaum, C. J. Swallow, M. D. Grynpas, et al. (2002)
J. Biol. Chem. 277, 19991-19997
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Shedding of the Interleukin-6 (IL-6) Receptor (gp80) Determines the Ability of IL-6 to Induce gp130 Phosphorylation in Human Osteoblasts.

C. Vermes, J. J. Jacobs, J. Zhang, G. Firneisz, K. A. Roebuck, and T. T. Glant (2002)
J. Biol. Chem. 277, 16879-16887
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Effect of Estrogen versus Testosterone on Circulating Osteoprotegerin and Other Cytokine Levels in Normal Elderly Men.

S. Khosla, E. J. Atkinson, C. R. Dunstan, and W. M. O'Fallon (2002)
J. Clin. Endocrinol. Metab. 87, 1550-1554
 |  Abstract »  |  Full Text »  |  PDF »

Relationship Between Interleukin-6 Production in the Lungs and Pulmonary Vascular Resistance in Patients With Congestive Heart Failure*.

N. Mabuchi, T. Tsutamoto, A. Wada, M. Ohnishi, K. Maeda, M. Hayashi, and M. Kinoshita (2002)
Chest 121, 1195-1202
 |  Abstract »  |  Full Text »  |  PDF »

Differential Response of Estrogen Receptors alpha and beta to SP500263, a Novel Potent Selective Estrogen Receptor Modulator.

H. Brady, M. Doubleday, L. M. Gayo-Fung, M. Hickman, S. Khammungkhune, A. Kois, S. Lipps, S. Pierce, N. Richard, G. Shevlin, et al. (2002)
Mol. Pharmacol. 61, 562-568
 |  Abstract »  |  Full Text »  |  PDF »

Changes in Proinflammatory Cytokine Activity after Menopause.

J. Pfeilschifter, R. Koditz, M. Pfohl, and H. Schatz (2002)
Endocr. Rev. 23, 90-119
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Estrogen Inhibition of PTH-Stimulated Osteoclast Formation and Attachment in Vitro: Involvement of Both PKA and PKC.

B.-Y. Liu, P.-W. Wu, F. R. Bringhurst, and J.-T. Wang (2002)
Endocrinology 143, 627-635
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Sex Steroids and Bone.

S.C. Manolagas, S. Kousteni, and R.L. Jilka (2002)
Recent Prog. Horm. Res. 57, 385-409
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen restores cellular immunity in injured male mice via suppression of interleukin-6 production.

K. A. N. Messingham, S. A. Heinrich, and E. J. Kovacs (2001)
J. Leukoc. Biol. 70, 887-895
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Reduces the Depth of Resorption Pits by Disturbing the Organic Bone Matrix Degradation Activity of Mature Osteoclasts.

V. Parikka, P. Lehenkari, M.-L. Sassi, J. Halleen, J. Risteli, P. Harkonen, and H. K. Vaananen (2001)
Endocrinology 142, 5371-5378
 |  Abstract »  |  Full Text »  |  PDF »

Altered Bax expression and decreased apoptosis in bone marrow cells of lupus-susceptible NZB/W mice.

M Nazareth, P Fanti, C Schwach, K Poppenberg, K Janis, and S M Aronica (2001)
Lupus 10, 785-793
 |  Abstract »  |  PDF »

IL-6 Negatively Regulates IL-11 Production in Vitro and in Vivo.

I. A. Nakchbandi, M. A. Mitnick, U. S. Masiukiewicz, B. h. Sun, and K. L. Insogna (2001)
Endocrinology 142, 3850-3856
 |  Abstract »  |  Full Text »  |  PDF »

Skeletal Effects of Developmental Lead Exposure in Rats.

M. J. J. Ronis, J. Aronson, G. G. Gao, W. Hogue, R. A. Skinner, T. M. Badger, and C. K. Lumpkin Jr. (2001)
Toxicol. Sci. 62, 321-329
 |  Abstract »  |  Full Text »  |  PDF »

Perspective: Nonreproductive Sites of Action of Reproductive Hormones.

S. C. Manolagas and S. Kousteni (2001)
Endocrinology 142, 2200-2204
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17{beta}-Estradiol Stimulates Expression of Osteoprotegerin by a Mouse Stromal Cell Line, ST-2, via Estrogen Receptor-{{alpha}}.

M. Saika, D. Inoue, S. Kido, and T. Matsumoto (2001)
Endocrinology 142, 2205-2212
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Characterization of a Novel Gene That Is Regulated by Estrogen and Is Associated with Mammary Gland Carcinogenesis.

D. Marcantonio, L. E. Chalifour, M. A. Alaoui-Jamali, L. Alpert, and H. T. Huynh (2001)
Endocrinology 142, 2409-2418
 |  Abstract »  |  Full Text »  |  PDF »

Serum Interleukin 6 Is a Major Predictor of Bone Loss in Women Specific to the First Decade Past Menopause.

C. Scheidt-Nave, H. Bismar, G. Leidig-Bruckner, H. Woitge, M. J. Seibel, R. Ziegler, and J. Pfeilschifter (2001)
J. Clin. Endocrinol. Metab. 86, 2032-2042
 |  Abstract »  |  Full Text »

The Effects of Particulate Wear Debris, Cytokines, and Growth Factors on the Functions of MG-63 Osteoblasts.

C. Vermes, R. Chandrasekaran, J. J. Jacobs, J. O. Galante, K. A. Roebuck, and T. T. Glant (2001)
J. Bone Joint Surg. Am. 83, 201
 |  Abstract »  |  Full Text »

The soluble interleukin 6 receptor: mechanisms of production and implications in disease.

S. A. JONES, S. HORIUCHI, N. TOPLEY, N. YAMAMOTO, and G. M. FULLER (2001)
FASEB J 15, 43-58
 |  Abstract »  |  Full Text »  |  PDF »

Sex Steroids and Bone.

J. E. Compston (2001)
Physiol Rev 81, 419-447
 |  Abstract »  |  Full Text »  |  PDF »

Serotonin Increases Interleukin-6 Synthesis in Human Vascular Smooth Muscle Cells.

T. Ito, U. Ikeda, M. Shimpo, K. Yamamoto, and K. Shimada (2000)
Circulation 102, 2522-2527
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Deficiency, Obesity, and Skeletal Abnormalities in Follicle-Stimulating Hormone Receptor Knockout (FORKO) Female Mice.

N. Danilovich, P. S. Babu, W. Xing, M. Gerdes, H. Krishnamurthy, and M. R. Sairam (2000)
Endocrinology 141, 4295-4308
 |  Abstract »  |  Full Text »  |  PDF »

Anti-interleukin 6 receptor antibody treatment in rheumatic disease.

N. Nishimoto, T. Kishimoto, and K. Yoshizaki (2000)
Ann Rheum Dis 59, i21-27
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Therapeutic Approaches to Bone Diseases.

G. A. Rodan and T. J. Martin (2000)
Science 289, 1508-1514
 |  Abstract »  |  Full Text »

Progression of Aortic Calcification Is Associated With Metacarpal Bone Loss During Menopause : A Population-Based Longitudinal Study.

A. E. Hak, H. A. P. Pols, A. M. van Hemert, A. Hofman, and J. C. M. Witteman (2000)
Arterioscler Thromb Vasc Biol 20, 1926-1931
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Modulates Parathyroid Hormone-Induced Interleukin-6 Production in Vivo and in Vitro.

U. S. Masiukiewicz, M. Mitnick, A. B. Grey, and K. L. Insogna (2000)
Endocrinology 141, 2526-2531
 |  Abstract »  |  Full Text »  |  PDF »

Altered bone marrow cell sensitivity in the lupus-prone NZB/W mouse: regulation of CFU-GM colony formation by estrogen, tamoxifen and thrombopoietin.

S M Aronica, A Dozier, P Fanti, and M Nazareth (2000)
Lupus 9, 271-277
 |  Abstract »  |  PDF »

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis.

S. C. Manolagas (2000)
Endocr. Rev. 21, 115-137
 |  Abstract »  |  Full Text »

Stimulation of Bone Formation in Vitro and in Rodents by Statins.

G. Mundy, R. Garrett, S. Harris, J. Chan, D. Chen, G. Rossini, B. Boyce, M. Zhao, and G. Gutierrez (1999)
Science 286, 1946-1949
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Editorial: Cell Number Versus Cell Vigor--What Really Matters to a Regenerating Skeleton?.

S. C. Manolagas (1999)
Endocrinology 140, 4377-4381
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The Expression of Interleukin-6 (IL-6), IL-6 Receptor, and gp130-Kilodalton Glycoprotein in the Rat Decidua and a Decidual Cell Line: Regulation by 17{beta}-Estradiol and Prolactin.

S. Deb, C. Tessier, A. Prigent-Tessier, U. Barkai, S. Ferguson-Gottschall, R. K. Srivastava, J. Faliszek, and G. Gibori (1999)
Endocrinology 140, 4442-4450
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A Role for Interleukin-6 in Parathyroid Hormone-Induced Bone Resorption in Vivo.

A. Grey, M.-A. Mitnick, U. Masiukiewicz, B.-H. Sun, S. Rudikoff, R. L. Jilka, S. C. Manolagas, and K. Insogna (1999)
Endocrinology 140, 4683-4690
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The Endocrinology of Aging.

H. M. Perry III (1999)
Clin. Chem. 45, 1369-1376
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Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption.

H. Yoshitake, S. R. Rittling, D. T. Denhardt, and M. Noda (1999)
PNAS 96, 8156-8160
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STAT3 Activation in Stromal/Osteoblastic Cells Is Required for Induction of the Receptor Activator of NF-kappa B Ligand and Stimulation of Osteoclastogenesis by gp130-utilizing Cytokines or Interleukin-1 but Not 1,25-Dihydroxyvitamin D3 or Parathyroid Hormone.

C. A. O'Brien, I. Gubrij, S.-C. Lin, R. L. Saylors, and S. C. Manolagas (1999)
J. Biol. Chem. 274, 19301-19308
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Estrogen Deficiency Accelerates Autoimmune Exocrinopathy in Murine Sjogren's Syndrome through Fas-Mediated Apoptosis.

N. Ishimaru, K. Saegusa, K. Yanagi, N. Haneji, I. Saito, and Y. Hayashi (1999)
Am. J. Pathol. 155, 173-181
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CD4+ T Cells and the Proinflammatory Cytokines Gamma Interferon and Interleukin-6 Contribute to Alveolar Bone Loss in Mice.

P. J. Baker, M. Dixon, R. T. Evans, L. Dufour, E. Johnson, and D. C. Roopenian (1999)
Infect. Immun. 67, 2804-2809
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Estrogen has rapid tissue-specific effects on rat bone.

R. T. Turner, L. S. Kidder, M. Zhang, S. A. Harris, K. C. Westerlind, A. Maran, and T. J. Wronski (1999)
J Appl Physiol 86, 1950-1958
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The Actions and Interactions of Sex Steroids and Growth Factors/Cytokines on the Skeleton.

T. C. Spelsberg, M. Subramaniam, B. L. Riggs, and S. Khosla (1999)
Mol. Endocrinol. 13, 819-828
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Role of the Osteoclast at the Bone-Implant Interface.

C. Minkin and V.C. Marinho (1999)
Advances in Dental Research 13, 49-56
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Amenorrheic Bone Loss.

K. K. Miller and A. Klibanski (1999)
J. Clin. Endocrinol. Metab. 84, 1775-1783
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Selective Effects of Genistein, a Soybean Isoflavone, on B-Lymphopoiesis and Bone Loss Caused by Estrogen Deficiency.

Y. Ishimi, C. Miyaura, M. Ohmura, Y. Onoe, T. Sato, Y. Uchiyama, M. Ito, X. Wang, T. Suda, and S. Ikegami (1999)
Endocrinology 140, 1893-1900
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Parathyroid Hormone-Related Protein (107-139) Stimulates Interleukin-6 Expression in Human Osteoblastic Cells.

F. DE MIGUEL, P. MARTINEZ-FERNANDEZ, C. GUILLEN, A. VALIN, A. RODRIGO, M. E. MARTINEZ, and P. ESBRIT (1999)
J. Am. Soc. Nephrol. 10, 796-803
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Platelet-derived Growth Factor Induces Interleukin-6 Transcription in Osteoblasts through the Activator Protein-1 Complex and Activating Transcription Factor-2.

N. Franchimont, D. Durant, S. Rydziel, and E. Canalis (1999)
J. Biol. Chem. 274, 6783-6789
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Walker 256/S Carcinosarcoma Causes Osteoporosis-like Changes through Ectopical Secretion of Luteinizing Hormone-releasing Hormone.

Y. Waki, M. Nomura, S. Kasugai, K. Ohya, and K.-i. Miyamoto (1999)
Cancer Res. 59, 1219-1224
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Macrophage Colony Stimulating-Factor Transcripts Are Differentially Regulated in Rat Bone-Marrow by Gender Hormones.

C. K. Lea, U. Sarma, and A. M. Flanagan (1999)
Endocrinology 140, 273-279
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Association of oestrogen receptor gene polymorphisms with age at onset of rheumatoid arthritis.

T. Ushiyama, K. Mori, K. Inoue, J. Huang, J. Nishioka, and S. Hukuda (1999)
Ann Rheum Dis 58, 7-10
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Soluble IL-6 Receptor Potentiates the Antagonistic Activity of Soluble gp130 on IL-6 Responses.

G. Muller-Newen, A. Kuster, U. Hemmann, R. Keul, U. Horsten, A. Martens, L. Graeve, J. Wijdenes, and P. C. Heinrich (1998)
J. Immunol. 161, 6347-6355
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Mode of Action of Interleukin-6 on Mature Osteoclasts. Novel Interactions with Extracellular Ca2+ Sensing in the Regulation of Osteoclastic Bone Resorption.

O. A. Adebanjo, B. S. Moonga, T. Yamate, L. Sun, C. Minkin, E. Abe, and M. Zaidi (1998)
J. Cell Biol. 142, 1347-1356
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Interleukin-13 Inhibits Cell Proliferation and Stimulates Interleukin-6 Formation in Isolated Human Osteoblasts.

A. Frost, K. B. Jonsson, H. Brändström, C. Ohlsson, S. Ljunghall, and O. Ljunggren (1998)
J. Clin. Endocrinol. Metab. 83, 3285-3289
 |  Abstract »  |  Full Text »

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